The early pathophysiologic understanding of angina pectoris
American Heart Association
Caleb Hillier Parry of Bath and Allan Burns of Glasgow formulated explanations of angina pectoris that stand as brilliant early examples of pathophysiologic reasoning. These astute observers proposed the concept that symptomatic ischemic heart disease results from a dynamic imbalance of myocardial energy supply and demand. Their work forms the basis of our traditional understanding of effort-related chest pain in obstructive coronary artery disease. © 1981.
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