Bioengineering aspects of heart valve replacement Academic Article Article uri icon


MeSH Major

  • Antineoplastic Agents
  • Biological Availability
  • Geriatric Assessment
  • Neoplasms


  • Biomedical engineering inputs have been important in the design, development and testing of substitute heart valves as well as in the pre- and post-operative management of patients with cardiac valve disease. This paper is a review of heart valve replacement whose goal is the enhancement of future bioengineering contributions. We review the approach to the patient with valvular heart disease, and the sources of early and late postoperative pathology with emphasis on complications of the prostheses used. Major significant problem areas relate to the noninvasive evaluation of cardiovascular function (both before and after surgery), device design, hemodynamics, and the need for thromboresistant and durable materials.

publication date

  • May 1982



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1007/BF02367460

PubMed ID

  • 6763846

Additional Document Info

start page

  • 97

end page

  • 128


  • 10


  • 3