The impact of total parenteral nutrition on liver function tests in patients with cancer Academic Article Article uri icon


MeSH Major

  • Dependovirus
  • Factor VIII
  • Genetic Therapy
  • Genetic Variation
  • Genetic Vectors
  • Hemophilia A


  • In 143 patients undergoing 199 cycles of total parenteral nutrition (TPN), alkaline phosphatase (AP), serum glutamic-oxaloacetic transaminase (SGOT), serum glutamic-pyruvic transaminase (SGPT), direct bilirubin (DB), total bilirubin (TB), and lactic dehydrogenase (LDH) were measured and recorded before initiating TPN and weekly for seven weeks or until TPN was discontinued. Patterns of change were elevations and then plateaued. Direct bilirubin, TB and LDH showed no significant change. The patterns were independent of patient age, amount of fat emulsion administered, tumor burden, and nonprotein calorie to basal energy expenditure ratio.

publication date

  • January 1982



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1002/1097-0142(19820315)49:6<1249::AID-CNCR2820490629>3.0.CO;2-D

PubMed ID

  • 6800631

Additional Document Info

start page

  • 1249

end page

  • 57


  • 49


  • 6