HLA frequencies in amyotrophic lateral sclerosis Academic Article uri icon

Overview

MeSH Major

  • Amyotrophic Lateral Sclerosis
  • HLA Antigens

abstract

  • Our study of the distribution of HLA-A, -B, and -C in patients with amyotrophic lateral sclerosis (ALS) found no statistically significant deviation. We found a trend, however, toward a decrease in HLA-A9, as we had reported previously, and toward an increase in HLA-Bw35 and -Cw4. The worldwide incidence of ALS is uniform except in Guam and on Japan's Kii peninsula, and published reports from many countries, including Guam, show no consistent deviation in HLA frequencies related to ALS.

publication date

  • January 1982

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 7073543

Additional Document Info

start page

  • 270

end page

  • 1

volume

  • 39

number

  • 5