IgA antibody to spermatozoa in seminal and prostatic fluids of a subfertile man Academic Article Article uri icon


MeSH Major

  • DNA
  • Genome-Wide Association Study
  • Nucleic Acid Amplification Techniques
  • Premature Birth
  • Specimen Handling


  • the mechanism of spontaneous sperm agglutination in the ejaculate of a subfertile man was investigated. Using enzyme-linked immunosorbent assays it was found that the patient's spermatozoa had a mean of 2.3 times more IgA bound to it than did spermatozoa from fertile men. IgA antibody to spermatozoa was also found in the patient's seminal fluid and prostatic fluid, but not in his serum. In this patient it appeared that agglutination was due to an IgA antibody to spermatozoa that was produced locally within the genital tract.

publication date

  • March 26, 1982



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1001/jama.247.7.1014

PubMed ID

  • 7057574

Additional Document Info

start page

  • 1014

end page

  • 5


  • 247


  • 7