Opportunistic infections and immune deficiency in homosexual men Academic Article uri icon

Overview

MeSH Major

  • Homosexuality
  • Immunologic Deficiency Syndromes
  • Infection

abstract

  • A syndrome of opportunistic infections and acquired immune deficiency occurred among four previously healthy homosexual men. Fever, leukopenia, and diminished delayed hypersensitivity were accompanied by various degrees of proctitis, perianal ulcerations, and lymphadenopathy. The infectious agents included Pneumocystis carinii, Cryptococcus neoformans, Candida albicans, herpes simplex virus, and cytomegalovirus. The immune deficiency was characterized as a persistent and profound selective decrease in the function as well as number of T lymphocytes of the helper/inducer subset and a possible activation of the suppressor/cytotoxic subset. Three patients died despite aggressive anti-infective therapy.

publication date

  • November 29, 1982

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 6283974

Additional Document Info

start page

  • 700

end page

  • 4

volume

  • 96

number

  • 6 I