Special characteristics of cellular immune function in normal individuals of the HLA-DR3 type Academic Article Article uri icon

Overview

MeSH Major

  • Rheumatology
  • Societies, Medical

abstract

  • Studies with a number of tests of in vitro cellular immune function have shown differences between DR3-positive normal individuals and those of other DR types. Increased Ig synthesis and decreased Con A-induced suppression were the most striking changes observed in this preliminary investigation. Further studies especially with additional suppressor cell assays appear waranted. The possibilities that such changes play a significant role in the development of diseases associated with the DR3 phenotype is discussed. © 1982.

publication date

  • January 1982

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/0090-1229(82)90113-1

PubMed ID

  • 6213340

Additional Document Info

start page

  • 269

end page

  • 74

volume

  • 23

number

  • 2