Randomized trial of standard therapy with or without poly I:C in patients with superficial bladder cancer Academic Article Article uri icon


MeSH Major

  • Acquired Immunodeficiency Syndrome


  • Thirty-two patients with superficial urinary bladder tumors were stratified for four variables and randomized after complete transurethral resection and/or fulguration of tumor to receive standard therapy with or without intravenous Poly I:C. Cystoscopies were performed at three- to four-month intervals for up to 48 months. While there was no statistically significant difference in the tumor recurrence rates in the two groups during the first year, a significant increase (P = 0.003) in survival at four years was observed between the Poly I:C group and the control group. The difficulties in evaluating the efficacy of anti-neoplastic agents in the treatment of superficial bladder tumors are discussed.

publication date

  • January 1981



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1002/1097-0142(19811115)48:10<2154::AID-CNCR2820481006>3.0.CO;2-X

PubMed ID

  • 7028242

Additional Document Info

start page

  • 2154

end page

  • 7


  • 48


  • 10