Teratogenic effects of antileukemic chemotherapy Academic Article Article uri icon

Overview

MeSH Major

  • Polycythemia Vera
  • Thrombocythemia, Essential

abstract

  • The clinical teratogenicity of the new antileukemic chemotherapeutic agents administered to mothers early in the first trimester of pregnancy is not well defined. Cytarabine and thioguanine were given in identical doses to the same mother during the first trimester of two separate pregnancies. Both pregnancies resulted in viable babies, one with and one without congenital malformations. This case illustrates the highly unpredictable clinical effects on the fetus of chemotherapy early in pregnancy.

publication date

  • January 1981

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1001/archinte.141.4.514

PubMed ID

  • 7212895

Additional Document Info

start page

  • 514

end page

  • 5

volume

  • 141

number

  • 4