MATERIALS DEGENERATION CAUSING LATE FAILURE OF MECHANICAL HEART VALVE PROSTHESES: PROBLEMS AND PROMISE. Academic Article uri icon

Overview

MeSH Major

  • Heart Valve Prosthesis Implantation
  • Image Enhancement
  • Magnetic Resonance Imaging, Cine
  • Mitral Valve
  • Mitral Valve Insufficiency

abstract

  • Materials degradation with resultant clinically significant valvular dysfunction has been an important late complication of cardiac valvular replacement with mechanical prostheses. Major mechanisms of failure are related to either lipid absorption by silicone elastomers or abrasive wear of polymers. In a review of the necropsies of 99 patients dying late after cardiac valvular replacement, two cases of fatal valve deterioration were encountered, one involving each of the above failure modes. By scanning electron microscopy and analytical surface profilometry, seven contemporary heart valve prostheses recovered frm this series were examined. All of them had no clinical or pathological evidence of degeneration/dysfunction, contained pyrolytic carbon components and had been in-situ for 30 months or longer. Results of this analysis suggest that progressive deterioration by abrasive wear of pyrolytic carbon heart valves will not be a significant problem.

publication date

  • December 1980

Research

keywords

  • Academic Article

Additional Document Info

start page

  • 269

end page

  • 282