Transglutaminase is essential in receptor-mediated endocytosis of α2-macroglobulin and polypeptide hormones Academic Article uri icon

Overview

MeSH Major

  • Fractures, Compression
  • Lumbar Vertebrae
  • Spinal Fractures
  • Thoracic Vertebrae

abstract

  • The receptor-mediated endocytosis of alpha 2-macroglobulin can be inhibited by a diverse group of chemical compounds all of which share the property of being inhibitors of one form of cellular transglutaminase. The present results strongly suggest that protein cross-linking may be essential for receptor-mediated endocytosis of some protein and polypeptide hormones.

publication date

  • December 1980

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1038/283162a0

Additional Document Info

start page

  • 162

end page

  • 7

volume

  • 283

number

  • 5743