Function of cryopreserved human effector cells in antibody-dependent, cell-mediated cytotoxicity Academic Article uri icon

Overview

MeSH Major

  • Antibody-Dependent Cell Cytotoxicity
  • Freezing
  • Lymphocytes

abstract

  • Cells active in an ADCC model were studied for their ability to withstand cryopreservation. For this model, we used the [3H]proline microcytotoxicity assay with fibroblast target cells and a serum containing lymphocyte-dependent antibody reactive with the alloantigens on those target cells. Human blood effector cells active in this system can be successfully cryopreserved with minor dimunition in function with standard techniques and concentrations between 9 and 12% DMSO.

publication date

  • December 1978

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 748801

Additional Document Info

start page

  • 93

end page

  • 5

volume

  • Monogr. 49