Measurement of liver blood flow in the dog using krypton-85 clearance: A comparison with electromagnetic flowmeter measurements Academic Article Article uri icon


MeSH Major

  • Echocardiography
  • Mitral Valve Insufficiency
  • Ultrasonography, Doppler


  • Blood flow in the superficial liver tissue was measured by recording the clearance rate of the β emissions of 85Kr following its injection into the portal vein. The flow values calculated from monoexponential clearance curves were compared to portal venous blood flow simultaneously recorded with a calibrated electromagnetic flow probe in six dogs whose hepatic artery had been ligated. The liver: blood partition coefficient of 85Kr was measured in these dogs and was found to be 0.91. There was a close correlation (r = 0.95) between the blood flow values obtained from the two techniques over a wide range of flow values. This shows that measurement of liver blood flow in the surface layers of the liver using the 85Kr clearance method provides a true reflection of the blood flow in the liver tissue as a whole. © 1978.

publication date

  • January 1978



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1016/0022-4804(78)90069-0

PubMed ID

  • 150474

Additional Document Info

start page

  • 147

end page

  • 53


  • 25


  • 2