Mass spectrometric identification and selected ion monitoring quantitation of γ-amino-butyric acid (GABA) in human lumbar cerebrospinal fluid Academic Article uri icon

Overview

MeSH Major

  • gamma-Aminobutyric Acid

abstract

  • The authors present here an unequivocal confirmation of the identification of GABA in human lumbar CSF by reporting complete mass spectral data. An SIM assay for quantitating this compound in such samples is also described. The quantitative procedure, which has been applied to the measurement of the GABA concentration in small volumes of human CSF, is of note because it lends itself to incorporation into the SIM procedures used to quantitate other acidic and neutral compounds in CSF without the expenditure of additional sample.

publication date

  • December 1978

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 151733

Additional Document Info

start page

  • 1119

end page

  • 22

volume

  • 31

number

  • 4