The role of DNA polymerase I-associated 5′-exonuclease in replication of coliphage M13 replicative-form DNA
Arthroplasty, Replacement, Knee
The conversion of both parental- and progeny-nascent open circular M13 RF DNA into covalently closed RF I is drastically reduced in an E. coli mutant deficient in the 5′ → 3′ exonuclease associated with DNA polymerase I. The nascent progeny RF DNA also contains a significant proportion of fragments of smaller than unit length. © 1977.
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