Nuclear magnetic resonance in cancer, XII: Application of nmr malignancy index to human lung tumours Academic Article Article uri icon


MeSH Major

  • Amniotic Fluid
  • Fetal Therapies
  • Prenatal Diagnosis


  • Sixty specimens of human lung tissue from 52 individuals were inspected at 22.5 MHz by proton magnetic resonance techniques. The purpose of the study was to evaluate the diagnostic capabilities of the nuclear magnetic resonance (NMR) technique for the diagnosis of malignancy. The combination of two NMR parameters (spin-lattice (T1) and spin-spin (T2) relaxation times) into a malignancy index yielded 3 cases of overlap between the two populations of tissue. The mean and standard deviations obtained were 1.966 +/- 0.262 for normal tissue, and 2.925 +/- 0.864 for malignant specimens. In addition, analysis of the electrolyte and water content of the tissues confirm that factors other than specimen water content influence the relaxation time.

publication date

  • January 1977



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1038/bjc.1977.183

PubMed ID

  • 911662

Additional Document Info

start page

  • 235

end page

  • 42


  • 36


  • 2