Glial-neural interaction demonstrated by the injection of Na+ and Li+ into cortical glia Academic Article uri icon

Overview

MeSH Major

  • Membrane Potentials
  • Neuroglia
  • Neurons

abstract

  • Injection of Na+ or Li+ into cortical glia evokes glial depolarization, discharge of adjacent neurons, and vascular pulsation. The effects can be explained by the extrusion of K+ from glia after cation injection, glial swelling, and the slow removal of the cation from glia. The data suggest that the reduced rate of reuptake of K+ into Na+-loaded glia results in epileptiform firing of neurons, and support the hypothesis that glia function to buffer the environment of neurons.

publication date

  • December 1977

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 831270

Additional Document Info

start page

  • 196

end page

  • 8

volume

  • 195

number

  • 4274