Spin label study of erythrocyte membrane fluidity in myotonic and Duchenne muscular dystrophy and congenital myotonia
Amyotrophic Lateral Sclerosis
INTACT erythrocyte membranes from patients with myotonic muscular dystrophy (MMD) have been shown by spin labelling (review of method in ref. 1) to have greater membrane surface fluidity than normal2,3. We have now evaluated the specificity of this phenomenon. We used erythrocytes from patients with MMD, and also from patients with Duchenne muscular dystrophy (DMD), as a model of dystrophy with no myotonia, and from patients with congenital myotonia (CM) as a model of myotonia without dystrophy. © 1976 Nature Publishing Group.
Digital Object Identifier (DOI)
Additional Document Info
has global citation frequency