The role of bone marrow aspiration and biopsy in detecting marrow involvement by nonhematologic malignancies Academic Article Article uri icon


MeSH Major

  • Cardiovascular Diseases
  • Genetic Variation
  • Indians, North American
  • Mannose-Binding Lectin


  • A review of the records of the Memorial Sloan-Kettering Cancer Center identified 291 adult patients with nonhematologic malignancies who had undergone simultaneous bone marrow aspiration and biopsy from the same anatomic site. In 236 cases both samples were negative for tumor whereas in 39 both were positive. The biopsy was positive in three patients with a negative aspirate whereas in three others to aspirate was positive with a negative biopsy. The higher rate of tumor detection on aspirate in comparison with previous reports may be due to a thorough initial screening provided by technologists. Both aspiration and biopsy appear to be indicated for full evaluation of bone marrow in cancer patients.

publication date

  • January 1976



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1002/1097-0142(197612)38:6<2401::AID-CNCR2820380628>3.0.CO;2-F

PubMed ID

  • 1000472

Additional Document Info

start page

  • 2401

end page

  • 3


  • 38


  • 6