Corticosteroid therapy in patients with cerebral tumors: benefits, mechanisms, problems, practicalities Review uri icon

Overview

MeSH Major

  • Adrenal Cortex Hormones
  • Brain Neoplasms

abstract

  • A short review of corticosteroid therapy in brain tumor patients is presented, including a short historical review and outline of clinical trials. The following aspects are dealt with: (1) The mechanisms of benefit: brain fluid compartments, the effect on brain tissue water, the affects on cerebrospinal fluid and brain blood volume, the effects on systemic sodium and water balance, the antitumor effect; (2) the problems in therapy; (3) practicalities: the dosage and administration, the drug-drug interactions and complications.

publication date

  • December 1975

Research

keywords

  • Review

Identity

Language

  • eng

PubMed ID

  • 795033

Additional Document Info

start page

  • 49

end page

  • 56

volume

  • 2

number

  • 1