Tryptoline formation by a preparation from brain with 5 methyltetrahydrofolic acid and tryptamine Academic Article uri icon

Overview

MeSH Major

  • Brain
  • Indoles
  • Tetrahydrofolates
  • Tissue Extracts
  • Tryptamines

abstract

  • An enzymatic preparation from human brain converts tryptamine to tryptoline (9H-1,2,3,4-tetrahydropyrido[3,4-b]indole) in the presence of 5-methyltetrahydrofolic acid. Similarly, N-methyltryptamine and 5-hydroxytryptamine yield 1-methyltryptoline and 5-hydroxytryptoline, respectively. Neither in vitro nor in vivo formation of these compounds by human tissues has been described.

publication date

  • December 1975

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 234627

Additional Document Info

start page

  • 853

end page

  • 5

volume

  • 187

number

  • 4179