Steroid 5α reductase deficiency in man: an inherited form of male pseudohermaphroditism Academic Article uri icon

Overview

MeSH Major

  • Disorders of Sex Development
  • Oxidoreductases

abstract

  • In male pseudohermaphrodites born with ambiguity of the external genitalia but with marked virilization at puberty, biochemical evaluation reveals a marked decrease in plasma dihydrotestosterone secondary to a decrease in steroid 5alpha-reductase activity. In utero the decrease in dihydrotestosterone results in incomplete masculinization of the external genitalia. Inheritance is autosomal recessive.

publication date

  • December 1974

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 4432067

Additional Document Info

start page

  • 1213

end page

  • 5

volume

  • 186

number

  • 4170