Pseudomonas aeruginosa endocarditis in a heroin addict was cured with polymyxin B sulfate, gentamicin sulfate and carbenicillin therapy. There are 46 published reports of pseudomonas endocarditis but only 5 well documented cases of successful treatment. Previous cardiac surgery had been carried out in 60 percent of recently reported cases, and 20 percent of all cases occurred after the use of intravenously administered narcotic agents or medication. Other predisposing conditions included skin infection and gastrointestinal or genitourinary tract infection or surgery. The suggested antibiotic regimen for pseudomonas endocarditis should include polymyxin B, gentamicin and probably carbenicillin in maximal tolerated doses for a minimal period of 6 to 8 weeks. © 1973 Dun • Donnelley Publishing corporation 666 Fifth Avenue, New York, New York 10019 All rights reserved.
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