Rapid transport of radioactivity in goldfish optic nerve following injections of labelled glucosamine Academic Article Article uri icon

Overview

MeSH Major

  • Nerve Regeneration
  • Optic Nerve
  • Proteins

abstract

  • Tritiated glucosamine injected into the goldfish eye is incorporated into acid-insoluble and chloroform-methanol-extractable materials which are rapidly transported through the optic nerve to the contralateral optic tectum. TCA-soluble material is also transported. Glucosamine incorporation is inhibited by acetoxycycloheximide. In contrast to the labeling of both rapidly transported and slowly transported proteins by amino acids, glucosamine labels only the fast component. This suggests that labeling with amino sugars may be a specific way of demonstrating fast axoplasmic transport. © 1971.

publication date

  • April 16, 1971

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/0006-8993(71)90529-4

PubMed ID

  • 4104274

Additional Document Info

start page

  • 119

end page

  • 30

volume

  • 28

number

  • 1