Histiocytic Medullary Reticulosis: The Role of Phagocytosis in Pancytopenia Academic Article Article uri icon

Overview

MeSH Major

  • Abortifacient Agents, Nonsteroidal
  • Misoprostol

abstract

  • Three patients presented with histiocytic medullary reticulosis. A review of 49 additional patients allowed an evaluation of the hematological aspects of this disease. Hemolytic anemia, granulocytopenia, and thrombocytopenia commonly observed in this disorder may result from excessive phagocytosis of blood cells by abnormal histiocytes within medullary centers of bone and lymphoid tissue. In addition, these histiocytes may serve as a repository for sequestered erythrocytic iron and cholesterol. © 1968, American Medical Association. All rights reserved.

publication date

  • January 1968

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1001/archinte.1968.00300080031007

PubMed ID

  • 5671102

Additional Document Info

start page

  • 223

end page

  • 9

volume

  • 122

number

  • 3