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Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.
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- TET1 is a tumor suppressor of hematopoietic malignancy. Nature immunology. 2015 Academic Article GET IT
- Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia. Cancer cell. 2015 Academic Article GET IT
- miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a. Blood. 2015 Academic Article GET IT
Notch pathway activation targets AML-initiating cell homeostasis and differentiation.
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TET family proteins and their role in stem cell differentiation and transformation.
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