The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.
Times cited: 785
- let-7 Overexpression leads to an increased fraction of cells in G2/M, direct down-regulation of Cdc34, and stabilization of Wee1 kinase in primary fibroblasts. The Journal of biological chemistry. 2009 Academic Article GET IT
An immunohistochemical method for identifying fibroblasts in formalin-fixed, paraffin-embedded tissue.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
Times cited: 53