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OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.
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- A positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeast. PLoS genetics. 2012 Academic Article GET IT
- Chemical genetic screen for AMPKα2 substrates uncovers a network of proteins involved in mitosis. Molecular cell. 2011 Academic Article GET IT
RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF.
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- Combining chemical genetics and proteomics to identify protein kinase substrates. Proceedings of the National Academy of Sciences of the United States of America. 2005 Academic Article GET IT