contributor
- Sonnenberg, Gregory F Head of Basic Research 2022 -
Medicine-Gastroenterology and Hepatology
Academic Department
Overview
Research
administers grant
- (PQ1) Adaptive immune and microbial mechanisms regulating Lynch syndrome penetrance
- A randomized, placebo-controlled clinical trial examining the efficacy of Fecal Microbiota Transplantation (FMT) and subsequent dietary fiber in patients with moderate ulcerative colitis (MINDFUL)
- Biopharma Agreement
- CAP-IT Center for LNP RNA Immunoprevention
- CHASE-EIM: Cohort for Healing Arthritis, Skin, and Eye Extra-Intestinal Manifestations
- CTLA-4 regulation of intestinal health and inflammation
- Cancer Immune-Interception for Lynch Syndrome
- Clinical Outcomes in Alcohol-associated Liver Disease
- Colorectal Cancer Prevention by a novel EPA analogue TP-252 and naproxen in FAP and lynch syndrome models
- Core B: Human Hepatocyte and Discovery
- Defining a novel mechanism of mucosal healing
- Defining a novel regulator of innate lymphoid cells and intestinal health
- Defining a novel transcriptional regulator of intestinal health and inflammation
- Defining host-microbe interactions in cancer and immunotherapy
- Defining mechanisms of immune tolerance to the intestinal microbiota
- Delineating the role of genetic mutations in Hepatoblastoma development and phenotypes
- EA Pharma Research Collaboration Agreement
- Elucidating the Role of MALAT1 Somatic Driver Mutations in Colorectal Cancer
- Emerging Therapeutic Paradigms in Inflammatory Bowel Disease
- Enhancing Immune Regulation In Gene Therapy For Hemophilia
- Fiber-induced Metabolites Promote UC Healing
- GARDE: Scalable Clinical Decision Support for Individualized Cancer Risk Management
- Hyperbaric Oxygen Therapy for Ulcerative Colitis Patients Hospitalized for Moderate to Severe Flares: A Phase 3 Multi-Center, Randomized, Double-Blind, Sham-Controlled Trial
- Immune regulation of intestinal health and disease
- In search of an HBV cure: novel model systems and targets
- Innate immune regulation of host-microbe interactions
- Innate immune regulation of neuroinflammation
- Innate lymphoid cell regulation of the host-microbiota interactions in cancer
- Innate-like lymphocyte regulation of host-microbiota interactions in cancer
- Integrated high-throughput functional assays to identify ulcerative colitis causal risk variants
- Interleukin-2 regulation of mucosal inflammation
- Interrogation of a Novel Immuno-Regulatory Pathway in Colitis-Associated Cancer
- Investigating molecular mechanisms behind gut bacterial transamination and IBD
- Launching HBV with RNA to assess antiviral resistance and explore fundamental aspects of virus-host biology
- Leveraging the Gut Microbiome to Regulate Hepatic Gluconeogenesis
- Liquid biopsy for liver cancer surveillance
- Long Title: System-Level Capture of Family History Data to Assess Risk of Cancer and provide Longitudinal Care Coordination
- Microbiota, Metabolites, and Colon Neoplasia
- Mid-terminal human synthetic liver organogenesis
- Modeling Hepatoblastoma using pluripotent stem cell derived hepatocyte-like cells
- Modeling alcohol toxicity in human hepatocytes
- Molecular and clinical characterization of IBD patients naive or refractory to standard of care over time
- Multidisciplinary Research Training in Gastroenterology and Hepatology
- Multidisciplinary Research Training in Gastroenterology and Hepatology
- Neoantigen Vaccination for Lynch Syndrome Immunoprevention
- Novel mechanisms protecting the gut from TNF
- Optimization of the engineered 3D hepatic microenvironment enhances pluripotent stem cell derived hepatocyte
- PREVENT Cancer Preclinical Drug Development Program: Preclinical Efficacy and Intermediate Endpoint Biomarkers
- Pregnancy in Inflammatory Bowel Disease And Neonatal Outcomes (PIANO)
- Project 3: Mechanisms of Innate and Adaptive Immune Responses to AAV-FVIII Gene Transfer
- Regulation of Enteric Nervous System Function by Group 3 Innate Lymphoid Cells
- Regulation of gut damage and inflammation through insulin-like growth factor-1
- Role for TL1A in innate intestinal inflammation and colitis associated cancer
- Role of SARS-CoV-2 ion channel ORF3a in COVID-19-associated thrombosis
- Strategies and Therapies for Outcomes Prevention in Cirrhosis: The STOP-C Liver Cirrhosis Network
- TL1A Regulation of Group 3 Innate Lymphoid Cells in Colitis
- The role of the microbiome and Notch signaling in esophageal adenocarcinoma
- Them1 Inhibitors for the Management of Non-Alcoholic Fatty Liver Disease
- Thioesterase-mediated lipotoxicity in liver and thermogenic adipose tissue
- Towards a preventive cancer vaccine for children with constitutional mismatch repair deficiency
- Vaccines against Fusobacterium Nucleatum for FAP- and Lynch Syndrome-associated-Option
- Validating novel DNA repair deficient cancer therapy targets and small molecule compounds
- Value Proposition & Market" and "Applicability to Future Infectious Disease Threats