Break-induced replication sparks CGG-repeat instability Academic Article uri icon

Overview

abstract

    • © 2018, The Publisher. The mechanism underlying CCG-repeat expansions in patients with fragile X premutation is not well understood. Using a new experimental system in mammalian cells, a study in this issue reports that break-induced replication has a role in CGG-repeat instability.

publication date

  • 2018

Identity

Digital Object Identifier (DOI)

    • 10.1038/s41594-018-0103-z

PubMed ID

    • 30061599