PLoS ONE

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Development and validation of a prognostic model predicting symptomatic hemorrhagic transformation in acute ischemic stroke at scale in the OHDSI network. 15:e0226718. 2020
Characterizing herpes simplex virus type 1 and type 2 seroprevalence declines and epidemiological association in the United States. 14. 2019
Aberrant gene expression by Sertoli cells in infertile men with Sertoli cell-only syndrome. 14. 2019
Developing a dynamic HIV transmission model for 6 U.S. cities: An evidence synthesis. 14. 2019
Dynamic modelling of an ACADS genotype in fatty acid oxidation - Application of cellular models for the analysis of common genetic variants. 14. 2019
Impact of HIV-1 infection on the IGF-1 axis and angiogenic factors in pregnant Cameroonian women receiving antiretroviral therapy. 14:e0215825. 2019
Pharmacodynamic study of radium-223 in men with bone metastatic castration resistant prostate cancer. 14. 2019
Herpes simplex virus type 1 epidemiology in Latin America and the Caribbean: Systematic review and meta-analytics. 14. 2019
Optimizing the production and affinity purification of HIV-1 envelope glycoprotein SOSIP trimers from transiently transfected CHO cells. 14. 2019
Retinoids induce antagonism between FOXO3A and FOXM1 transcription factors in human oral squamous cell carcinoma (OSCC) cells. 14. 2019
The impact of bariatric surgery on asthma control differs among obese individuals with reported prior or current asthma, with or without metabolic syndrome. 14. 2019
Validation of publicly-available software used in analyzing NGS data for HIV-1 drug resistance mutations and transmission networks in a Washington, DC, Cohort. 14. 2019
A non-randomized trial to assess the safety, tolerability, and pharmacokinetics of posaconazole oral suspension in immunocompromised children with neutropenia. 14. 2019
Genetic and epigenetic profiling of the infertile male. 14:e0214275. 2019
An efficient and cost-effective method for purification of small sized DNAs and RNAs from human urine. 14:e0210813. 2019
Community health workers trained to conduct verbal autopsies provide better mortality measures than existing surveillance: Results from a cross-sectional study in rural western Uganda. 14:e0211482. 2019
PCSK9 loss-of-function variants and risk of infection and sepsis in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort. 14:e0210808. 2019
Reproducibility of pharmacogenetics findings for paclitaxel in a heterogeneous population of patients with lung cancer. 14:e0212097. 2019
(-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells. 14. 2019
An augmented reality system for image guidance of transcatheter procedures for structural heart disease. 14. 2019
Association of electroretinography with visual outcomes after ophthalmic artery chemosurgery for retinoblastoma in ICRb D and E eyes. 14. 2019
Corneal nerve and endothelial cell damage in patients with transient ischemic attack and minor ischemic stroke. 14:e0213319. 2019
Dengue and chikungunya seroprevalence among Qatari nationals and immigrants residing in Qatar. 14. 2019
Effects of AM80 compared to AC261066 in a high fat diet mouse model of liver disease. 14. 2019
Extracellular matrix turnover and inflammation in chemically-induced TMJ arthritis mouse models. 14:e0223244. 2019
Genetic codes optimized as a traveling salesman problem. 14. 2019
Impact of CodY protein on metabolism, sporulation and virulence in Clostridioides difficile ribotype 027. 14. 2019
Male sexual dysfunction in obesity: The role of sex hormones and small fibre neuropathy. 14:e0221992. 2019
Mechanical effects of MitraClip on leaflet stress and myocardial strain in functional mitral regurgitation - A finite element modeling study. 14:e0223472. 2019
Molecular characterization of viruses associated with encephalitis in São Paulo, Brazil. 14. 2019
Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization. 14. 2019
Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action. 14. 2019
Potential causes of early death among admitted newborns in a rural Tanzanian hospital. 14:e0222935. 2019
Revisiting aneuploidy profile of surgically retrieved spermatozoa by whole exome sequencing molecular karyotype. 14. 2019
Use of topical versus injectable anaesthesia for ShangRing circumcisions in men and boys in Kenya: Results from a randomized controlled trial. 14. 2019
Virome capture sequencing does not identify active viral infection in unicentric and idiopathic multicentric Castleman disease. 14. 2019
Increased Alzheimer’s risk during the menopause transition: A 3-year longitudinal brain imaging study. 13:e0207885. 2018
Multiple configurations of EGFR exon 20 resistance mutations after first- and third-generation EGFR TKI treatment affect treatment options in NSCLC. 13:e0208097. 2018
Ablation of nasal-associated lymphoid tissue does not affect focal ischemic brain injury in mice. 13:e0205470. 2018
Implementation of a novel continuous fetal Doppler (Moyo) improves quality of intrapartum fetal heart rate monitoring in a resource-limited tertiary hospital in Tanzania: An observational study. 13:e0205698. 2018
Region-specific susceptibility change in cognitively impaired patients with diabetes mellitus. 13:e0205797. 2018
Tissue engineering the human auricle by auricular chondrocyte-mesenchymal stem cell co-implantation. 13:e0202356. 2018
Adult mortality trends in Qatar, 1989-2015: National population versus migrants. 13:e0203996. 2018
Evaluation of surfactant proteins A, B, C, and D in articular cartilage, synovial membrane and synovial fluid of healthy as well as patients with osteoarthritis and rheumatoid arthritis. 13:e0203502. 2018
Exome sequencing-based identification of novel type 2 diabetes risk allele loci in the Qatari population. 13:e0199837. 2018
Integrating the skin and blood transcriptomes and serum proteome in hidradenitis suppurativa reveals complement dysregulation and a plasma cell signature. 13:e0203672. 2018
An in-vivo pilot study into the effects of FDG-mNP in cancer in mice. 13:e0202482. 2018
Comparison of two different methods of image analysis for the assessment of microglial activation in patients with multiple sclerosis using (R)-[N-methyl-carbon-11] PK11195. 13:e0201289. 2018
Post-hospital mortality in children aged 2-12 years in Tanzania: A prospective cohort study. 13:e0202334. 2018
Predicting death and lost to follow-up among adults initiating antiretroviral therapy in resource-limited settings: Derivation and external validation of a risk score in Haiti. 13:e0201945. 2018
Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer. 13:e0199012. 2018
The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis. 13:e0200486. 2018
AR negative triple negative or “Quadruple Negative” breast cancers in African American women have an enriched basal and immune signature. 13:e0196909. 2018
Anatomic measurements of cerebral venous sinuses in idiopathic intracranial hypertension patients. 13:e0196275. 2018
Association of functional and structural social support with medication adherence among individuals treated for coronary heart disease risk factors: Findings from the REasons for Geographic and Racial Differences in Stroke (REGARDS) study. 13:e0198578. 2018
Children with type 1 diabetes who experienced a honeymoon phase had significantly lower LDL cholesterol 5 years after diagnosis. 13:e0196912. 2018
Growth patterns of survivors of retinoblastoma treated with ophthalmic artery chemosurgery. 13:e0197052. 2018
Impact of left ventricular diastolic function and survival in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement. 13:e0196031. 2018
TMSOTf assisted synthesis of 2’-deoxy-2’-[¹⁸F] fluoro-β-D-arabinofuranosylcytosine ([¹⁸F] FAC). 13:e0196784. 2018
Ten-year experience with ophthalmic artery chemosurgery: Ocular and recurrence-free survival. 13:e0197081. 2018
Whole blood transcriptional profiles as a prognostic tool in complete and incomplete Kawasaki Disease. 13:e0197858. 2018
Aspirin use and long-term rates of sepsis: A population-based cohort study. 13:e0194829. 2018
Mild cognitive dysfunction of caregivers and its association with care recipients’ end-of-life plans and preferences. 13:e0196147. 2018
Pharmacogenetic landscape of metabolic syndrome components drug response in Tunisia and comparison with worldwide populations. 13:e0194842. 2018
Readmission prediction via deep contextual embedding of clinical concepts. 13:e0195024. 2018
Temporal evolution of HIV sero-discordancy patterns among stable couples in sub-Saharan Africa. 13:e0196613. 2018
Total retinal detachments due to retinoblastoma: Outcomes following intraarterial chemotherapy/ophthalmic artery chemosurgery. 13:e0195395. 2018
A care bundle including antenatal corticosteroids reduces preterm infant mortality in Tanzania a low resource country. 13:e0193146. 2018
Peripheral neuropathy in patients with multiple sclerosis. 13:e0193270. 2018
Racial disparities in the prevalence and control of hypertension among a cohort of HIV-infected patients in the southeastern United States. 13:e0194940. 2018
The influence of age, anthropometric and metabolic variables on LDIFLARE and corneal confocal microscopy in healthy individuals. 13:e0193452. 2018
Why west? Comparisons of clinical, genetic and molecular features of infants with and without spasms. 13:e0193599. 2018
Synthesis, stabilization, and characterization of the MR1 ligand precursor 5-amino-6-D-ribitylaminouracil (5-A-RU). 13. 2018
The nonlinear relationship between cerebrospinal fluid Aβ42 and tau in preclinical Alzheimer’s disease. 13:e0191240. 2018
Electrocardiographic left atrial abnormality and silent vascular brain injury: The Northern Manhattan Study. 13:e0203774. 2018
Is obstructive sleep apnea associated with difficult airway? Evidence from a systematic review and meta-analysis of prospective and retrospective cohort studies. 13:e0204904. 2018
Lower serum IgA is associated with COPD exacerbation risk in SPIROMICS. 13:e0194924. 2018
Predictors of death including quality of positive pressure ventilation during newborn resuscitation and the relationship to outcome at seven days in a rural Tanzanian hospital. 13:e0202641. 2018
Preliminary study of tumor heterogeneity in imaging predicts two year survival in pancreatic cancer patients. 12:e0188022. 2017
Association between diabetes mellitus and active tuberculosis: A systematic review and meta-analysis. 12:e0187967. 2017
Membrane order in the plasma membrane and endocytic recycling compartment. 12:e0188041. 2017
Treatment with solubilized Silk-Derived Protein (SDP) enhances rabbit corneal epithelial wound healing. 12:e0188154. 2017
HIV protease inhibitor-induced cardiac dysfunction and fibrosis is mediated by platelet-derived TGF-β1 and can be suppressed by exogenous carbon monoxide. 12:e0187185. 2017
Perimenopause and emergence of an Alzheimer’s bioenergetic phenotype in brain and periphery. 12:e0185926. 2017
Total disc replacement using tissue-engineered intervertebral discs in the canine cervical spine. 12:e0185716. 2017
XX Disorder of Sex Development is associated with an insertion on chromosome 9 and downregulation of RSPO1 in dogs (Canis lupus familiaris). 12:e0186331. 2017
Multiplanar strain quantification for assessment of right ventricular dysfunction and non-ischemic fibrosis among patients with ischemic mitral regurgitation. 12:e0185657. 2017
SIRT1 is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis. 12:e0185236. 2017
The effect of HIV infection and HCV viremia on inflammatory mediators and hepatic injury—The Women’s Interagency HIV Study. 12:e0181004. 2017
Time to publication of oncology trials and why some trials are never published. 12:e0184025. 2017
Variability in objective and subjective measures affects baseline values in studies of patients with COPD. 12:e0184606. 2017
Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors. 12:e0180541. 2017
Carbon nanotubes exhibit fibrillar pharmacology in primates. 12:e0183902. 2017
Corneal confocal microscopy is a rapid reproducible ophthalmic technique for quantifying corneal nerve abnormalities. 12:e0183040. 2017
D-cycloserine improves synaptic transmission in an animal mode of Rett syndrome. 12:e0183026. 2017
Expression of PD-L1 and other immunotherapeutic targets in thymic epithelial tumors. 12:e0182665. 2017
The prevalence and incidence of active syphilis in women in Morocco, 1995-2016: Model-based estimation and implications for STI surveillance. 12:e0181498. 2017
Delineation of the role of chromatin assembly and the Rtt101^Mms1 E3 ubiquitin ligase in DNA damage checkpoint recovery in budding yeast. 12:e0180556. 2017
Diagnostic utility of corneal confocal microscopy and intra-epidermal nerve fibre density in diabetic neuropathy. 12:e0180175. 2017
Effects of exogenous glucagon-like peptide-2 and distal bowel resection on intestinal and systemic adaptive responses in rats. 12:e0181453. 2017
Effects of oxidative and thermal stresses on stress granule formation in human induced pluripotent stem cells. 12:e0182059. 2017
Enriched environment and stress exposure influence splenic B lymphocyte composition. 12:e0180771. 2017
Tumor Necrosis Factor dynamically regulates the mRNA stabilome in rheumatoid arthritis fibroblast-like synoviocytes. 12:e0179762. 2017
A phase i study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors. 12:e0178593. 2017
Migrants, healthy worker effect, and mortality trends in the Gulf Cooperation Council countries. 12:e0179711. 2017
Successful implementation of helping babies survive and helping mothers survive programs-An utstein formula for newborn and maternal survival. 12:e0178073. 2017
The association between various smoking behaviors, cotinine biomarkers and skin autofluorescence, a marker for advanced glycation end product accumulation. 12:e0179330. 2017
Total control of fat cells from adipogenesis to apoptosis using a xanthene analog. 12:e0179158. 2017
Treatment with macrolides and glucocorticosteroids in severe communityacquired pneumonia: A post-hoc exploratory analysis of a randomized controlled trial. 12:e0178022. 2017
A predictive model for lack of partial clinical remission in new-onset pediatric type 1 diabetes. 12:e0176860. 2017
Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation. 12:e0176562. 2017
Inflammatory biomarkers as predictors of heart failure in women without obstructive coronary artery disease: A report from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE). 12:e0177684. 2017
Risk factors for hepatitis C seropositivity among young people who inject drugs in New York City: Implications for prevention. 12:e0177341. 2017
SIRT1 is a positive regulator of the master osteoblast transcription factor, RUNX2. 12:e0178520. 2017
Antimicrobial-resistant infections among postpartum women at a Ugandan referral hospital. 12:e0175456. 2017
MAIT cells are reduced in frequency and functionally impaired in human T lymphotropic virus type 1 infection: Potential clinical implications. 12:e0175345. 2017
Outcomes after antiretroviral therapy during the expansion of HIV services in Haiti. 12:e0175521. 2017
Sliding scale HCG trigger yields equivalent pregnancy outcomes and reduces ovarian hyperstimulation syndrome: Analysis of 10,427 IVF-ICSI cycles. 12:e0176019. 2017
Distance in cancer gene expression from stem cells predicts patient survival. 12:e0173589. 2017
Right atrial volume by cardiovascular magnetic resonance predicts mortality in patients with heart failure with reduced ejection fraction. 12:e0173245. 2017
Waterpipe smoking induces epigenetic changes in the small airway epithelium. 12:e0171112. 2017
A cyclin-dependent kinase inhibitor, dinaciclib in preclinical treatment models of thyroid cancer. 12:e0172315. 2017
Chemotherapy induces adaptive drug resistance and metastatic potentials via phenotypic CXCR4-expressing cell state transition in ovarian cancer. 12:e0171044. 2017
Patient experience with outpatient encounters at public hospitals in Shanghai: Examining different aspects of physician services and implications of overcrowding. 12:e0171684. 2017
A low peripheral blood CD4/CD8 ratio is associated with pulmonary emphysema in HIV. 12:e0170857. 2017
Assessment of corneal sensation, innervation and retinal nerve fiber layer in patients treated with multiple intravitreal ranibizumab injections. 12:e0170271. 2017
Could circumcision of HIV-positive males benefit voluntary medical male circumcision programs in Africa? Mathematical modeling analysis. 12:e0170641. 2017
HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers. 12:e0181886. 2017
Human Papillomavirus (HPV) infection: Molecular epidemiology, genotyping, seroprevalence and associated risk factors among Arab women in Qatar. 12:e0169197. 2017
Imaging radiation-induced gastrointestinal, bone marrow injury and recovery kinetics using ¹⁸F-FDG PET. 12:e0169082. 2017
Mesenchymal cell reprogramming in experimental MPL^W515L mouse model of myelofibrosis. 12:e0166014. 2017
Rare synaptogenesis-impairing mutations in SLITRK5 are associated with obsessive compulsive disorder. 12:e0169994. 2017
Relationship between clinical parameters and brain structure in sporadic amyotrophic lateral sclerosis patients according to onset type: A voxel-based morphometric study. 12:e0168424. 2017
Review and analysis of publication trends over three decades in three high impact medicine journals. 12:e0170056. 2017
The Systematic Evaluation of Identifying the Infarct Related Artery Utilizing Cardiac Magnetic Resonance in Patients Presenting with ST-Elevation Myocardial Infarction. 12:e0169108. 2017
The burden of mental disorders in the eastern mediterranean region, 1990-2013. 12:e0169575. 2017
The phage lysin PlySs2 Decolonizes Streptococcus suis from murine intranasal mucosa. 12:e0169180. 2017
Direct unequal cleavages: Embryo developmental competence, genetic constitution and clinical outcome. 11:e0166398. 2016
Lymph node transplantation decreases swelling and restores immune responses in a transgenic model of lymphedema. 11:e0168259. 2016
Structural mapping and functional characterization of zebrafish class B G-protein coupled receptor (GPCR) with dual ligand selectivity towards GLP-1 and glucagon. 11:e0167718. 2016
CDH1 missense variant c.1679C>G (p. T560R) completely disrupts normal splicing through creation of a novel 5′ splice site. 11:e0165654. 2016
How do qataris source health information?. 11:e0166250. 2016
Identifying maternal constraints on fetal growth and subsequent perinatal outcomes using a multiple embryo implantation model. 11:e0166222. 2016
P16^INK4aexpression and immunologic aging in chronic HIV infection. 11:e0166759. 2016
Quantitative multi-parametric magnetic resonance imaging of tumor response to photodynamic therapy. 11:e0165759. 2016
Anti-epidermal growth factor receptor gene therapy for glioblastoma. 11. 2016
Integrated left ventricular global transcriptome and proteome profiling in human end-stage dilated cardiomyopathy. 11:e0162669. 2016
Resolution of pulsatile tinnitus after venous sinus stenting in patients with Idiopathic Intracranial Hypertension. 11:e0164466. 2016
The transcriptional signature of active tuberculosis reflects symptom status in extra-pulmonary and pulmonary tuberculosis. 11:e0162220. 2016
Circulating plasma levels of MicroRNA-21 and MicroRNA-221 are potential diagnostic markers for primary intrahepatic cholangiocarcinoma. 11:e0163699. 2016
Detection of IgG Anti-leishmania antigen by flow cytometry as a diagnostic test for cutaneous leishmaniasis. 11. 2016
Microbial characterization of Qatari Barchans and Dunes. 11:e0161836. 2016
Novel metabolic abnormalities in the tricarboxylic acid cycle in peripheral cells from huntington's disease patients. 11. 2016
Obligatory role of EP1 receptors in the increase in cerebral blood flow produced by hypercapnia in the mice. 11:e0163329. 2016
Quantitation of murine stroma and selective purification of the human tumor component of patient-derived xenografts for genomic analysis. 11. 2016
Tumor-infiltrating macrophages in post-transplant, relapsed classical Hodgkin lymphoma are donor-derived. 11:e0163559. 2016
Validation of the Arabic version of calgary depression scale for schizophrenia. 11. 2016
ATmprss2-CreER^T2 knock-in mouse model for cancer genetic studies on prostate and colon. 11:e0161084. 2016
HIV-1-specific antibody response and function after DNA prime and recombinant adenovirus 5 boost HIV vaccine in HIV-infected subjects. 11:e0160341. 2016
SWEF proteins distinctly control maintenance and differentiation of hematopoietic stem cells. 11:e0161060. 2016
Six-SOMAmer index relating to immune, protease and angiogenic functions predicts progression in IPF. 11:e0159878. 2016
Spontaneous changes in taste sensitivity of single units recorded over consecutive days in the brainstem of the awake rat. 11:e0160143. 2016
Multiparametric classification of skin from osteogenesis imperfecta patients and controls by quantitative magnetic resonance microimaging. 11:e0157891. 2016
PARP inhibitors in clinical use induce genomic instability in normal human cells. 11:e0159341. 2016
Pitavastatin differentially modulates MicroRNA-Associated cholesterol transport proteins in macrophages. 11:e0159130. 2016
Sepsis caused by extended-spectrum beta-lactamase (ESBL)-positive K. pneumoniae and E. coli: Comparison of severity of sepsis, delay of anti-infective therapy and ESBL genotype. 11:e0158039. 2016
Significance of epicardial and intrathoracic adipose tissue volume among type 1 diabetes patients in the DCCT/EDIC: A pilot study. 11:e0159958. 2016
Type 2 diabetes risk allele loci in the Qatari population. 11:e0156834. 2016
Association between placental lesions, cytokines and angiogenic factors in pregnant women with preeclampsia. 11:e0157584. 2016
Malaria parasite clag3, a protein linked to nutrient channels, participates in high molecular weight membrane-associated complexes in the infected erythrocyte. 11:e0157390. 2016
Protective effect of dual-strain probiotics in preterm infants: A multi-center time series analysis. 11:e0158136. 2016
Simultaneous bilateral ophthalmic artery chemosurgery for bilateral retinoblastoma (tandem therapy). 11:e0156806. 2016
Specific metabolic markers are associated with future waist-gaining phenotype in women. 11:e0157733. 2016
Abdominal obesity, race and chronic kidney disease in young adults: Results from NHANES 1999-2010. 11:e0153588. 2016
Analysis of thrombophilia test ordering practices at an academic center: A proposal for appropriate testing to reduce harm and cost. 11:e0155326. 2016
Impact of the sensory neurons on melanoma growth in vivo. 11:e0156095. 2016
Neonatal mortality of planned home birth in the United States in relation to professional certification of birth attendants. 11:e0155721. 2016
Overcoming resistance of cancer cells to PARP-1 inhibitors with three different drug combinations. 11:e0155711. 2016
The commercial antibodies widely used to measure H3 K56 acetylation are non-specific in human and drosophila cells. 11:e0155409. 2016
A single amino acid substitution prevents recognition of a dominant human aquaporin-4 determinant in the context of HLA-DRB1-03:01 by a murine TCR. 11:e0152720. 2016
Body site is a more determinant factor than human population diversity in the healthy skin microbiome. 11:e0151990. 2016
Genetic influences on metabolite levels: A comparison across metabolomic platforms. 11:e0153672. 2016
Ghrelin inhibits post-operative adhesions via blockage of the TGF-β signaling pathway. 11:e0153968. 2016
Molecular Self-Assembly strategy for generating catalytic hybrid polypeptides. 11:e0153700. 2016
The pharmacogenetic footprint of ACE inhibition: A population-based metabolomics study. 11:e0153163. 2016
CHOP chemotherapy for aggressive non-Hodgkin lymphoma with and without HIV in the antiretroviral therapy era in Malawi. 11:e0150445. 2016
Comparative effectiveness of etanercept and adalimumab in patient reported outcomes and injection-related tolerability. 11:e0149781. 2016
Diagnosis of HIV-Associated oral lesions in relation to early versus delayed antiretroviral therapy: Results from the CIPRA HT001 Trial. 11:e0150656. 2016
Parameterization for in-silico modeling of ion channel interactions with drugs. 11:e0150761. 2016
Polarity-dependent misperception of subjective visual vertical during and after transcranial direct current stimulation (tDCS). 11:e0152331. 2016
Shedding light on the nature of seminal round cells. 11:e0151640. 2016
The role of biliary carcinoembryonic antigen-related cellular adhesion molecule 6 (CEACAM6) a sa biomarker in cholangiocarcinoma. 11:e0150195. 2016
Topotecan delivery to the optic nerve after ophthalmic artery chemosurgery. 11:e0151343. 2016
α1-Syntrophin variant identified in drug-induced long QT syndrome increases late sodium current. 11:e0152355. 2016
Analysis of transcriptional signatures in response to listeria monocytogenes infection reveals temporal changes that result from type i interferon signaling. 11:e0150251. 2016
Association of Forced Vital Capacity with the Developmental Gene NCOR2. 11:e0147388. 2016
Do case rates affect physicians' clinical practice in radiation oncology?: An observational study. 11:e0149449. 2016
Modeling the cost effectiveness of neuroimaging-based treatment of acute wake-up stroke. 11:e0148106. 2016
Morphological and hemodynamic discriminators for rupture status in posterior communicating artery aneurysms. 11:e0149906. 2016
Non-classical monocytes and monocyte chemoattractant protein-1 (MCP-1) correlate with coronary artery calcium progression in chronically HIV-1 infected adults on stable antiretroviral therapy. 11. 2016
Trends in CD4 count testing, retention in Pre-ART care, and ART initiation rates over the first decade of expansion of HIV services in Haiti. 11:e0146903. 2016
Intra-arterial chemotherapy (ophthalmic artery chemosurgery) for group D retinoblastoma. 11:e0146582. 2016
Targeted curing of all lysogenic bacteriophage from streptococcus pyogenes using a novel counter-selection technique. 11:e0146408. 2016
A germline variant on chromosome 4q31.1 associates with susceptibility to developing colon cancer metastasis. 11:e0146435. 2016
Serum biomarkers associated with clinical outcomes fail to predict brain metastases in patients with stage IV non-small cell lung cancers. 11:e0146063. 2016
The influence of tissue ischemia time on RNA integrity and patient-derived xenografts (PDX) engraftment rate in a non-small cell lung cancer (NSCLC) Biobank. 11:e0145100. 2016
Alterations in Lipid and Inositol Metabolisms in Two Dopaminergic Disorders. 11:e0147129. 2016
Anticipatory posturing of the vocal tract reveals dissociation of speech movement plans from linguistic units. 11:e0146813. 2016
Are early relapses in advanced-stage ovarian cancer doomed to a poor prognosis?. 11:e0147787. 2016
Association of right ventricular pressure and volume overload with non-ischemic septal fibrosis on cardiac magnetic resonance. 11:e0147349. 2016
Frequent Users of Hospital Emergency Departments in Korea Characterized by Claims Data from the National Health Insurance: A Cross Sectional Study. 11:e0147450. 2016
KS-detect validation of solar thermal PCR for the diagnosis of kaposi's sarcoma using pseudo-biopsy samples. 11:e0147636. 2016
Optical imaging of PARP1 in response to radiation in oral squamous cell carcinoma. 11:e0147752. 2016
SsDNA aptamer specifically targets and selectively delivers cytotoxic drug doxorubicin to HepG2 Cells. 11:e0147674. 2016
Advanced unilateral retinoblastoma: The impact of ophthalmic artery chemosurgery on Enucleation rate and patient survival at MSKCC. 10:e0145436. 2015
Comprehensible predictive modeling using regularized logistic regression and comorbidity based features. 10:e0144439. 2015
Development and validation of a gene-based model for outcome prediction in germ cell tumors using a combined genomic and expression profiling approach. 10:e0142846. 2015
Elimination of chromosomal Island SpyCIM1 from Streptococcus pyogenes strain SF370 reverses the mutator phenotype and alters global transcription. 10:e0145884. 2015
Investigating voluntary medical male circumcision program efficiency gains through subpopulation prioritization: Insights from application to Zambia. 10:e0145729. 2015
Risk of ischemic stroke after intracranial hemorrhage in patients with atrial fibrillation. 10:e0145579. 2015
Serum metabolite biomarkers discriminate healthy smokers from COPD smokers. 10:e0143937. 2015
Chronic diseases in North-West Tanzania and Southern Uganda. Public perceptions of terminologies, aetiologies, symptoms and preferred management. 10:e0142194. 2015
Whole exome sequencing of rapid autopsy tumors and xenograft models reveals possible driver mutations underlying tumor progression. 10:e0142631. 2015
Bilayer effects of antimalarial compounds. 10:e0142401. 2015
IRF4-dependent and IRF4-independent pathways contribute to DC dysfunction in lupus. 10:e0141927. 2015
A reevaluation of the voluntary medical male circumcision scale-up plan in Zimbabwe. 10:e0140818. 2015
Quality control measures over 30 years in a multicenter clinical study: Results from the Diabetes Control and Complications Trial / Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study. 10:e0141286. 2015
A Versatile Strategy for Production of Membrane Proteins with Diverse Topologies: Application to Investigation of Bacterial Homologues of Human Divalent Metal Ion and Nucleoside Transporters. 10:e0143010. 2015
A second look at the association between gender and mortality on antiretroviral therapy. 10:e0142101. 2015
Use of tethered enzymes as a platform technology for rapid analyte detection. 10:e0142326. 2015
Corneal sensitivity and dry eye symptoms in patients with keratoconus. 10:e0141621. 2015
Distinct transcript isoforms of the atypical chemokine receptor 1 (ACKR1) / Duffy Antigen Receptor for Chemokines (DARC) gene are expressed in lymphoblasts and altered isoform levels are associated with genetic ancestry and the duffy-null allele. 10:e0140098. 2015
Estimating sampling selection bias in human genetics: A phenomenological approach. 10:e0140146. 2015
Corneal confocal microscopy detects small fibre neuropathy in patients with upper gastrointestinal cancer and nerve regeneration in chemotherapy induced peripheral neuropathy. 10:e0139394. 2015
Tissue-specific enrichment of lymphoma risk loci in regulatory elements. 10:e0139360. 2015
The role of flexible loops in folding, trafficking and activity of equilibrative nucleoside transporters. 10:e0136779. 2015
Evaluation of in vitro activity of the class i PI3K inhibitor buparlisib (BKM120) in pediatric bone and soft tissue sarcomas. 10:e0133610. 2015
TMPyP4, a stabilizer of nucleic acid secondary structure, is a novel acetylcholinesterase inhibitor. 10:e0139167. 2015
Combined effects of flow diverting strategies and parent artery curvature on aneurysmal hemodynamics: A CFD study. 10:e0138648. 2015
Severe nephrotoxic nephritis following conditional and kidney-specific knockdown of stanniocalcin-1. 10:e0138440. 2015
A Multiplex PCR/LDR Assay for the simultaneous identification of category a infectious pathogens: Agents of viral hemorrhagic fever and Variola virus. 10:e0138484. 2015
Heterogeneous disease trajectories explain variable radiographic, function and quality of life outcomes in the Canadian Early Arthritis Cohort (CATCH). 10:e0135327. 2015
The effect of tear supplementation on ocular surface sensations during the interblink interval in patients with dry eye. 10:e0135629. 2015
Glucose metabolism disorders, HIV and antiretroviral therapy among tanzanian adults. 10:e0134410. 2015
Phase II trial of sorafenib in patients with chemotherapy refractory metastatic esophageal and gastroesophageal (GE) junction cancer. 10:e0134731. 2015
Measurement of lipid accumulation in Chlorella vulgaris via flow cytometry and liquid-state ¹H NMR spectroscopy for development of an NMR-traceable flow cytometry protocol. 10:e0134846. 2015
Prothrombin time and activated Partial Thromboplastin Time testing: A comparative effectiveness study in a million-patient sample. 10:e0133317. 2015
Knowledge, attitudes, practices and beliefs about Medical Male Circumcision (MMC) among a sample of health care providers in Haiti. 10:e0134667. 2015
Cholangiocarcinoma: Correlation between molecular profiling and imaging phenotypes. 10:e0132953. 2015
Predictors of clinical success in the treatment of patients with methicillin- resistant staphylococcus aureus (MRSA) Nosocomial pneumonia (NP). 10:e0131932. 2015
Reduced right ventricular function predicts long-term cardiac re-hospitalization after cardiac surgery. 10:e0132808. 2015
The validity of claims-based algorithms to identify serious hypersensitivity reactions and osteonecrosis of the jaw. 10:e0131601. 2015
Dual transcriptomic profiling of host and microbiota during health and disease in pediatric asthma. 10:e0131819. 2015
Targeting homologous recombination in Notch-driven C. elegans stem cell and human tumors. 10:e0127862. 2015
Social network analysis for program implementation. 10:e0131712. 2015
Tumor-targeted human T cells expressing CD28-based chimeric antigen receptors circumvent CTLA-4 inhibition. 10:e0130518. 2015
Defining the value of future research to identify the preferred treatment of meniscal tear in the presence of knee osteoarthritis. 10:e0130256. 2015
Improved intraoperative visualization of nerves through a myelin-binding fluorophore and dual-mode laparoscopic imaging. 10:e0130276. 2015
Seneca valley virus 3Cpro substrate optimization yields efficient substrates for use in peptide-prodrug therapy. 10:e0129103. 2015
Multiplexing of ChIP-seq samples in an optimized experimental condition has minimal impact on peak detection. 10:e0129350. 2015
Proton pump inhibitor usage and the risk of myocardial infarction in the general population. 10:e0124653. 2015
Expression of HIF-1α and markers of angiogenesis are not significantly different in triple negative breast cancer compared to other breast cancer molecular subtypes: Implications for future therapy. 10:e0129356. 2015
Identification of reprogrammed myeloid cell transcriptomes in NSCLC. 10:e0129123. 2015
Th2 cytokines inhibit lymphangiogenesis. 10:e0126908. 2015
Consider the source: Adolescents and adults similarly follow older adult advice more than peer advice. 10:e0128047. 2015
Colonization history, host distribution, anthropogenic influence and landscape features shape populations of white pine blister rust, an invasive alien tree pathogen. 10. 2015
The group 3 innate lymphoid cell defect in aryl hydrocarbon receptor deficient mice is associated with T cell hyperactivation during intestinal infection. 10:e0128335. 2015
Identification of DRG-1 as a melanoma-associated antigen recognized by CD4+ Th1 cells. 10:e0124094. 2015
Identification of Rv3852 as an agrimophol-binding protein in mycobacterium tuberculosis. 10:e0126211. 2015
Expression of the carboxy-terminal portion of MUC16/CA125 induces transformation and tumor invasion. 10:e0126633. 2015
Mitochondrial Mutations in Subjects with Psychiatric Disorders. 10:e0127280. 2015
Newly exerted T cell pressures on mutated epitopes following transmission help maintain consensus HIV-1 sequences. 10:e0120787. 2015
Protein expression profiles characterize distinct features of mouse cerebral cortices at different developmental stages. 10:e0125608. 2015
Characterization of bacterial and fungal microbiome in children with Hirschsprung disease with and without a history of enterocolitis:A multicenter study. 10:e0124172. 2015
Interrogating a multifactorial model of breast conserving therapy with clinical data. 10:e0125006. 2015
Side-by-side comparison of commonly used biomolecules that differ in size and affinity on tumor uptake and internalization. 10:e0124440. 2015
A novel small-molecule inhibitor targeting CREB-CBP complex possesses anti-cancer effects along with cell cycle regulation, autophagy suppression and endoplasmic reticulum stress. 10:e0122628. 2015
Cell signaling-based classifier predicts response to induction therapy in elderly patients with acute myeloid leukemia. 10:e0118485. 2015
Persistence of smoking-induced dysregulation of MiRNA expression in the small airway epithelium despite smoking cessation. 10:e0120824. 2015
The p53R172H mutant does not enhance hepatocellular carcinoma development and progression. 10:e0123816. 2015
Reversible linkage of two distinct small molecule inhibitors of myc generates a dimeric inhibitor with improved potency that is active in myc over-expressing cancer cell lines. 10:e0121793. 2015
Systems biology analysis merging phenotype, metabolomic and genomic data identifies Non-SMC Condensin I Complex, Subunit G (NCAPG) and cellular maintenance processes as major contributors to genetic variability in Bovine feed efficiency. 10:e0124574. 2015
Characterization of tetratricopeptide repeat-containing proteins critical for cilia formation and function. 10:e0124378. 2015
Corneal confocal microscopy detects neuropathy in patients with type 1 diabetes without retinopathy or microalbuminuria. 10:e0123517. 2015
Analyses of the transcriptome and metabolome demonstrate that HIF1α mediates altered tumor metabolism in clear cell renal cell carcinoma. 10:e0120649. 2015
Assessing associations between the AURKAHMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers. 10:e0120020. 2015
Folate receptor-a (FOLR1) expression and function in triple negative tumors. 10. 2015
Folate receptor-α (FOLR1) expression and function in triple negative tumors. 10. 2015
Gut microbiota and tacrolimus dosing in kidney transplantation. 10:e0122399. 2015
Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression. 10:e0120295. 2015
Small RNA sequencing for profiling MicroRNAs in long-term preserved formalin-fixed and paraffin-embedded non-small cell lung cancer tumor specimens. 10:e0121521. 2015
Gp120/CD4 blocking antibodies are frequently elicited in ART-naïve chronically HIV-1 infected individuals. 10:e0120648. 2015
Placental expression of miR-517a/b and miR-517c contributes to trophoblast dysfunction and preeclampsia. 10:e0122707. 2015
Colorectal mucus binds DC-SIGN and inhibits HIV-1 trans-infection of CD4+ T-lymphocytes. 10:e0122020. 2015
Inherited variation at MC1R and histological characteristics of primary melanoma. 10:e0119920. 2015
Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor- beta1 in pulmonary fibrosis. 10:e0121246. 2015
Hedgehog Signaling Pathway Is Active in GBM with GLI1 mRNA Expression Showing a Single Continuous Distribution Rather than Discrete High/Low Clusters. 10:e0116390. 2015
Recall of briefly presented chess positions and its relation to chess skill. 10:e0118756. 2015
Influence of intraaortic balloon pump counterpulsation on transesophageal echocardiography derived determinants of diastolic function. 10:e0118788. 2015
Is metabolic syndrome predictive of prevalence, extent, and risk of coronary artery disease beyond its components? results from the multinational coronary ct angiography evaluation for clinical outcome: An international multicenter registry (confirm). 10:e0118998. 2015
Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway. 10. 2015
Expression of Ror2 mediates invasive phenotypes in renal cell carcinoma. 9:e116101. 2014
Patterns in place of cancer death in the state of qatar: A population-based study. 9:e109615. 2014
A simplified score to quantify comorbidity in COPD. 9:e114438. 2014
An integrative computational approach for prioritization of genomic variants. 9:e114903. 2014
Mesothelin expression in triple negative breast carcinomas correlates significantly with basal-like phenotype, distant metastases and decreased survival. 9:e114900. 2014
Combined Ablation and Resection (CARe) as an effective parenchymal sparing treatment for extensive colorectal liver metastases. 9:e114404. 2014
The Charlson comorbidity index can be used prospectively to identify patients who will incur high future costs. 9:e112479. 2014
The role of lipotoxicity in smoke cardiomyopathy. 9:e113739. 2014
Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network. 9:e111301. 2014
Intracytoplasmic Sperm Injection (ICSI) in extreme cases of male infertility. 9:e113671. 2014
Mechanistic insight into the Th1-biased immune response to recombinant subunit vaccines delivered by probiotic bacteria-derived outer membrane vesicles. 9:e112802. 2014
Sleeping beauty mouse models identify candidate genes involved in gliomagenesis. 9:e113489. 2014
Endothelial cells provide a notch-dependent pro-tumoral niche for enhancing breast cancer survival, stemness and pro-metastatic properties. 9:e112424. 2014
Identification of molecular pathways facilitating Glioma cell invasion in situ. 9:e111783. 2014
Evaluation of toll-like receptor 2 and 4 RNA expression and the cytokine profile in postmenopausal women with metabolic syndrome. 9:e109259. 2014
Human equilibrative nucleoside transporter-1 knockdown tunes cellular mechanics through epithelial-mesenchymal transition in pancreatic cancer cells. 9:e107973. 2014
MRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon cancer patients in randomized CALGB 89803 trial. 9:e108483. 2014
Risk factors for severe neutropenia following intra-arterial chemotherapy for intra-ocular retinoblastoma. 9:e108692. 2014
Evaluation of intereye corneal asymmetry in patients with keratoconus. A Scheimpflug imaging study. 9:e108882. 2014
A multicenter phase l/ll study of obatoclax mesylate administered as a 3- Or 24-hour infusion in older patients with previously untreated acute myeloid leukemia. 9:e108694. 2014
Talpid3-binding centrosomal protein Cep120 is required for centriole duplication and proliferation of cerebellar granule neuron progenitors. 9:e107943. 2014
Accurate identification of ALK positive lung carcinoma patients: Novel FDA-cleared automated fluorescence in situ hybridization scanning system and ultrasensitive immunohistochemistry. 9:e107200. 2014
Conserved microsatellites in ants enable population genetic and colony pedigree studies across a wide range of species. 9:e107334. 2014
Health effects of lesion localization in multiple sclerosis: Spatial registration and confounding adjustment. 9. 2014
Knock out of S1P3 receptor signaling attenuates inflammation and fibrosis in bleomycin-induced lung Injury Mice Model. 9:e106792. 2014
A recommendation for revised dose calibrator measurement procedures for 89Zr and 124I. 9:e106868. 2014
Genitourinary defects associated with genomic deletions in 2p15 encompassing OTX1. 9:e107028. 2014
How accurate is MOLLI T1 mapping in vivo? Validation by spin echo methods. 9:e107327. 2014
Interleukin-4 regulates eomesodermin in CD8⁺ T cell development and differentiation. 9:e106659. 2014
Population structure of mountain pine beetle symbiont Leptographium longiclavatum and the implication on the multipartite beetle-fungi relationships. 9. 2014
Survival after acute hemodialysis in Pennsylvania, 2005-2007: A retrospective cohort study. 9:e105083. 2014
Remodeling of the methylation landscape in breast cancer metastasis. 9:e103896. 2014
Gene expression analysis of children with acute hematogenous osteomyelitis caused by methicillin-resistant staphylococcus aureus: Correlation with clinical severity of illness. 9:e103523. 2014
SIRT2 deficiency modulates macrophage polarization and susceptibility to experimental colitis. 9:e103573. 2014
Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism. 9:e102978. 2014
Both canonical and non-canonical Wnt signaling independently promote stem cell growth in mammospheres. 9:e101800. 2014
Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer. 9:e102495. 2014
Genetic variation in DNA repair pathways and risk of non-Hodgkin's lymphoma. 9:e101685. 2014
Cost-effectiveness of the "Helping Babies Breathe" program in a Missionary Hospital in rural Tanzania. 9:e102080. 2014
The roles of individual mammalian argonautes in RNA interference in vivo. 9:e101749. 2014
Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas. 9:e101010. 2014
cAMP control of HCN2 channel Mg2+ block reveals loose coupling between the cyclic nucleotide-gating ring and the pore. 9:e101236. 2014
Sugar-sweetened beverage intake and cancer recurrence and survival in CALGB 89803 (Alliance). 9:e99816. 2014
Multiparametric MRI analysis for the identification of high intensity focused ultrasound-treated tumor tissue. 9:e99936. 2014
Rat middle cerebral artery occlusion is not a suitable model for the study of stroke-induced spontaneous infections. 9:e99169. 2014
Ubiquitin Specific Protease 26 (USP26) expression analysis in human testicular and extragonadal tissues indicates diverse action of USP26 in cell differentiation and tumorigenesis. 9:e98638. 2014
Development of a novel multiplex PCR assay to detect functional subtypes of KIR3DL1 alleles. 9:e99543. 2014
P wave area for quantitative electrocardiographic assessment of left atrial remodeling. 9:e99178. 2014
Multi-compartment T2 relaxometry using a spatially constrained multi-Gaussian model. 9:e98391. 2014
Wnt signaling activates Shh signaling in early postnatal intervertebral discs, and re-activates Shh signaling in old discs in the mouse. 9:e98444. 2014
Continuous quality improvement in daily clinical practice: A proof of concept study. 9:e97066. 2014
Identification of the key differential transcriptional responses of human whole blood following TLR2 or TLR4 ligation in-vitro. 9:e97702. 2014
Safety, pharmacokinetic, and functional effects of the Nogo-A monoclonal antibody in amyotrophic lateral sclerosis: A randomized, first-in-human clinical trial. 9:e97803. 2014
The hepatitis C cascade of care: Identifying priorities to improve clinical outcomes. 9:e97317. 2014
Mucosal immunization with integrase-defective lentiviral vectors protects against influenza virus challenge in mice. 9:e97270. 2014
Simplification to abacavir/lamivudine + atazanavir maintains viral suppression and improves bone and renal biomarkers in ASSURE, a randomized, open label, non-inferiority trial. 9:e96187. 2014
Intermediate-type vancomycin resistance (VISA) in genetically-distinct staphylococcus aureus isolates is linked to specific, reversible metabolic alterations. 9:e97137. 2014
Baseline natural killer and T cell populations correlation with virologic outcome after regimen simplification to atazanavir/ritonavir alone (ACTG 5201). 9:e95524. 2014
Continuing a cancer treatment despite tumor growth may be valuable: Sunitinib in renal cell carcinoma as example. 9:e96316. 2014
Loss of function of TET2 cooperates with constitutively active KIT in murine and human models of mastocytosis. 9:e96209. 2014
Brain without anatomy: Construction and comparison of fully network-driven structural MRI connectomes. 9:e96196. 2014
A comparison of supervised machine learning algorithms and feature vectors for MS lesion segmentation using multimodal structural MRI. 9. 2014
Inhibition of breast cancer metastasis suppressor 1 promotes a mesenchymal phenotype in lung epithelial cells that express oncogenic k-rasv12and loss of p53. 9:e95869. 2014
Conditional reverse tet-transactivator mouse strains for the efficient induction of tre-regulated transgenes in mice. 9:e95236. 2014
Mapping the genetic architecture of gene regulation in whole blood. 9:e93844. 2014
Activation of GPER-1 estradiol receptor downregulates production of testosterone in isolated rat leydig cells and adult human testis. 9:e92425. 2014
Completely ES cell-derived mice produced by tetraploid complementation using inner cell mass (ICM) deficient blastocysts. 9:e94730. 2014
Micro-environment causes reversible changes in DNA methylation and mRNA expression profiles in patient-derived glioma stem cells. 9:e94045. 2014
Emphysema predicts hospitalisation and incident airflow obstruction among older smokers: A prospective cohort study. 9:e93221. 2014
Metabolic signatures of cultured human adipocytes from metabolically healthy versus unhealthy obese individuals. 9:e93148. 2014
Discovering aptamers by cell-SELEX against human soluble growth factors ectopically expressed on yeast cell surface. 9:e93052. 2014
The association between adiposity, mental well-being, and quality of life in extreme obesity. 9:e92859. 2014
Early Clostridium difficile infection during allogeneic hematopoietic stem cell transplantation. 9:e90158. 2014
Pregnancy differentially impacts performance of latent tuberculosis diagnostics in a high-burden setting. 9:e92308. 2014
Vaccination against endogenous retrotransposable element consensus sequences does not protect rhesus macaques from SIVsmE660 infection and replication. 9:e92012. 2014
Endotoxin-induced monocytic microparticles have contrasting effects on endothelial inflammatory responses. 9:e91597. 2014
Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection. 9. 2014
Identification of novel CELSR1 mutations in spina bifida. 9:e92207. 2014
Signaling role of prokineticin 2 on the estrous cycle of female mice. 9:e90860. 2014
Psychological stress and 30-day all-cause hospital readmission in acute coronary syndrome patients: An observational cohort study. 9:e91477. 2014
Putative transcriptomic biomarkers in the inflammatory cytokine pathway differentiate major depressive disorder patients from control subjects and bipolar disorder patients. 9. 2014
An active learning approach for rapid characterization of endothelial cells in human tumors. 9:e90495. 2014
Correlation between genotypic and phenotypic testing for resistance to rifampin in Mycobacterium tuberculosis clinical isolates in Haiti: Investigation of cases with discrepant susceptibility results. 9:e90569. 2014
Dual mode action of mangiferin in mouse liver under high fat diet. 9:e90137. 2014
The warmer the weather, the more gram-negative bacteria - Impact of temperature on clinical isolates in intensive care units. 9:e91105. 2014
IL-17 induces an expanded range of downstream genes in reconstituted human epidermis model. 9:e90284. 2014
Monocytes expand with immune dysregulation and is associated with insulin resistance in older individuals with chronic HIV. 9. 2014
Impact of antiretroviral therapy on renal function among HIV-infected tanzanian adults: A retrospective cohort study. 9:e89573. 2014
Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase. 9:e89938. 2014
Self-gated free-breathing 3D coronary CINE imaging with simultaneous water and fat visualization. 9:e89315. 2014
Cannabinoid neuromodulation in the adult early visual cortex. 9:e87362. 2014
Self-reported history of childhood smoking is associated with an increased risk for peripheral arterial disease independent of lifetime smoking burden. 9:e88972. 2014
Transient mild hyperthermia induces e-selectin mediated localization of mesoporous silicon vectors in solid tumors. 9:e86489. 2014
Healthcare worker perceived barriers to early initiation of antiretroviral and tuberculosis therapy among tanzanian inpatients. 9:e87584. 2014
Estimating risk of C. difficile transmission from PCR positive but cytotoxin negative cases. 9:e88262. 2014
Integration of sequence data from a consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene. 9:e87645. 2014
Drug-induced trafficking of P-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C. 9:e88154. 2014
Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2. 9:e88051. 2014
The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes. 9:e87941. 2014
A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events. 9:e87361. 2014
Trkb signaling in pericytes is required for cardiac microvessel stabilization. 9:e87406. 2014
Metabolomic derangements are associated with mortality in critically ill adult patients. 9:e87538. 2014
Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells. 9:e79987. 2014
Urine microRNA as potential biomarkers of autosomal dominant polycystic kidney disease progression: Description of miRNA profiles at baseline. 9:e86856. 2014
Regulatory T cell ablation causes acute T cell lymphopenia. 9:e86762. 2014
Composition and function of T cell subpopulations are slow to change despite effective antiretroviral treatment of HIV disease. 9:e85613. 2014
Electroretinogram monitoring of dose-dependent toxicity after ophthalmic artery chemosurgery in retinoblastoma eyes: Six year review. 9:e84247. 2014
Intraflagellar transport gene expression associated with short cilia in smoking and COPD. 9:e85453. 2014
Interleukin-21 is a critical regulator of CD4 and CD8 T cell survival during priming under interleukin-2 deprivation conditions. 9:e85882. 2014
Pyruvate protects pathogenic spirochetes from H2O2 killing. 9. 2014
A CACNA1C variant associated with reduced voltage-dependent inactivation, increased Ca<inf>V</inf>1.2 channel window current, and arrhythmogenesis. 9:e106982. 2014
Enhanced immunogenicity of HIV-1 envelope gp140 proteins fused to APRIL. 9:e107683. 2014
Circulating tumor cells from prostate cancer patients interact with E-selectin under physiologic blood flow. 8:e85143. 2013
Myeloid cell sirtuin-1 expression does not alter host immune responses to gram-negative endotoxemia or gram-positive bacterial infection. 8:e84481. 2013
Growth pattern analysis of murine lung neoplasms by advanced semi-automated quantification of micro-CT images. 8:e83806. 2013
Microfluidic generated EGF-gradients induce chemokinesis of transplantable retinal progenitor cells via the JAK/STAT and PI3kinase signaling pathways. 8:e83906. 2013
Barriers to malaria control among marginalized tribal communities: A qualitative study. 8:e81966. 2013
Molecular mechanisms mediating a deficit in recall of fear extinction in adult mice exposed to cocaine in utero. 8:e84165. 2013
The impact of a diabetes local enhanced service on quality outcome framework diabetes outcomes. 8:e83738. 2013
The sodium/proline transporter PutP of Helicobacter pylori. 8:e83576. 2013
Enhanced responses to tumor immunization following total body irradiation are time-dependent. 8:e82496. 2013
CD86 is an activation receptor for nk cell cytotoxicity against tumor cells. 8:e83913. 2013
Gene expression profiles accurately predict outcome following liver resection in patients with metastatic colorectal cancer. 8:e81680. 2013
Lack of RNase L attenuates macrophage functions. 8:e81269. 2013
Central role for MCP-1/CCL2 in injury-induced inflammation revealed by in vitro, in silico, and clinical studies. 8:e79804. 2013
Colorimetric and longitudinal analysis of leukocoria in recreational photographs of children with retinoblastoma.. 8:e76677. 2013
Correlated spontaneous activity persists in adult retina and is suppressed by inhibitory inputs.. 8:e77658. 2013
IKKα/CHUK regulates extracellular matrix remodeling independent of its kinase activity to facilitate articular chondrocyte differentiation.. 8:e73024. 2013
Risk factors associated with the community-acquired colonization of extended-spectrum beta-lactamase (ESBL) positive Escherichia Coli. an exploratory case-control study.. 8:e74323. 2013
A machine learning approach to automated structural network analysis: Application to neonatal encephalopathy. 8:e78824. 2013
Polymorphisms in alcohol metabolism genes ADH1B and ALDH2, alcohol consumption and colorectal cancer. 8:e80158. 2013
Persistence of hepatitis C virus during and after otherwise clinically successful treatment of chronic hepatitis C with standard pegylated interferon α-2b and ribavirin therapy. 8:e80078. 2013
Analysis of morphological parameters to differentiate rupture status in anterior communicating artery aneurysms. 8:e79635. 2013
Quantifying cancer absolute risk and cancer mortality in the presence of competing events after a myotonic dystrophy diagnosis. 8:e79851. 2013
DOK2 inhibits EGFR-mutated lung adenocarcinoma. 8:e79526. 2013
Eukaryotic Initiation Factor 2α - a Downstream Effector of Mammalian Target of Rapamycin - Modulates DNA Repair and Cancer Response to Treatment. 8:e77260. 2013
Metformin Targets the Metabolic Achilles Heel of Human Pancreatic Cancer Stem Cells. 8:e76518. 2013
M.tuberculosis Mutants Lacking Oxygenated Mycolates Show Increased Immunogenicity and Protective Efficacy as Compared to M. bovis BCG Vaccine in an Experimental Mouse Model. 8:e76442. 2013
Isolation of Clostridium perfringens Type B in an Individual at First Clinical Presentation of Multiple Sclerosis Provides Clues for Environmental Triggers of the Disease. 8:e76359. 2013
Activation Associated ERK1/2 Signaling Impairments in CD8⁺ T Cells Co-Localize with Blunted Polyclonal and HIV-1 Specific Effector Functions in Early Untreated HIV-1 Infection. 8. 2013
Identification of Genes Potentially Regulated by Human Polynucleotide Phosphorylase (hPNPase^old-35) Using Melanoma as a Model. 8. 2013
Utility of a Histone Deacetylase Inhibitor (PXD101) for Thyroid Cancer Treatment. 8:e77684. 2013
Targeted Exome Sequencing Integrated with Clinicopathological Information Reveals Novel and Rare Mutations in Atypical, Suspected and Unknown Cases of Alport Syndrome or Proteinuria. 8. 2013
CATP-6, a C. elegans Ortholog of ATP13A2 PARK9, Positively Regulates GEM-1, an SLC16A Transporter. 8:e77202. 2013
An Animal Explant Model for the Study of Human Cutaneous Squamous Cell Carcinoma. 8:e76156. 2013
Identification of Leptospira interrogans Phospholipase C as a Novel Virulence Factor Responsible for Intracellular Free Calcium Ion Elevation during Macrophage Death. 8:e75652. 2013
Simulation of Platelet, Thrombus and Erythrocyte Hydrodynamic Interactions in a 3D Arteriole with In Vivo Comparison. 8:e76949. 2013
SQSTM1/p62 Interacts with HDAC6 and Regulates Deacetylase Activity. 8:e76016. 2013
Meaning Making in Cancer Survivors: A Focus Group Study. 8:e76089. 2013
Small Molecule Injection into Single-Cell C. elegans Embryos via Carbon-Reinforced Nanopipettes. 8:e75712. 2013
IL-1Β Enriched Monocytes Mount Massive IL-6 Responses to Common Inflammatory Triggers among Chronically HIV-1 Infected Adults on Stable Anti-Retroviral Therapy at Risk for Cardiovascular Disease. 8. 2013
Deficiency in Repair of the Mitochondrial Genome Sensitizes Proliferating Myoblasts to Oxidative Damage. 8:e75201. 2013
Duration of Anti-Tuberculosis Therapy and Timing of Antiretroviral Therapy Initiation: Association with Mortality in HIV-Related Tuberculosis. 8:e74057. 2013
Interferon Signature in the Blood in Inflammatory Common Variable Immune Deficiency. 8:e74893. 2013
An Absolute Risk Model to Identify Individuals at Elevated Risk for Pancreatic Cancer in the General Population. 8:e72311. 2013
HIV-1 Envelope Glycoprotein Resistance to Monoclonal Antibody 2G12 Is Subject-Specific and Context-Dependent in Macaques and Humans. 8:e75277. 2013
High Correlation of the Response of Upper and Lower Lobe Small Airway Epithelium to Smoking. 8:e72669. 2013
Factors Secreted by Endothelial Progenitor Cells Enhance Neurorepair Responses after Cerebral Ischemia in Mice. 8:e73244. 2013
Spectrum of Ocular Manifestations in CLN2-Associated Batten (Jansky-Bielschowsky) Disease Correlate with Advancing Age and Deteriorating Neurological Function. 8:e73128. 2013
Carboplatin +/- Topotecan Ophthalmic Artery Chemosurgery for Intraocular Retinoblastoma. 8:e72441. 2013
Tissue plasminogen activator in trabecular meshwork attenuates steroid induced outflow resistance in mice. 8:e72447. 2013
Deep Tissue Injury in Development of Pressure Ulcers: A Decrease of Inflammasome Activation and Changes in Human Skin Morphology in Response to Aging and Mechanical Load. 8:e69223. 2013
Obesity Impairs Lymphatic Fluid Transport and Dendritic Cell Migration to Lymph Nodes. 8:e70703. 2013
An Investigation into the Strength of the Association and Agreement Levels between Subjective and Objective Sleep Duration in Adolescents. 8:e72406. 2013
Development of a New Approach to Aid in Visual Identification of Murine iPS Colonies Using a Fuzzy Logic Decision Support System. 8:e70605. 2013
Adenoviral Transduction of Human Acid Sphingomyelinase into Neo-Angiogenic Endothelium Radiosensitizes Tumor Cure. 8:e69025. 2013
Association between Bone Mineral Density and Incidence of Breast Cancer. 8:e70980. 2013
Chemoirradiation for Glioblastoma Multiforme: The National Cancer Institute Experience. 8:e70745. 2013
Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers. 8:e70630. 2013
TP53 and Let-7a micro-RNA Regulate K-Ras Activity in HCT116 Colorectal Cancer Cells. 8:e70604. 2013
Mortality Trends in Women and Men Presenting with Acute Coronary Syndrome: Insights from a 20-Year Registry. 8:e70066. 2013
The Relative Expression of Mig6 and EGFR Is Associated with Resistance to EGFR Kinase Inhibitors. 8:e68966. 2013
NF-κB Regulates Mesenchymal Transition for the Induction of Non-Small Cell Lung Cancer Initiating Cells. 8:e68597. 2013
Whole Cell Screen for Inhibitors of pH Homeostasis in Mycobacterium tuberculosis. 8:e68942. 2013
An Apparent Lack of Epidemiologic Association between Hepatitis C Virus Knowledge and the Prevalence of Hepatitis C Infection in a National Survey in Egypt. 8:e69803. 2013
Mutations in Planar Cell Polarity Gene SCRIB Are Associated with Spina Bifida. 8:e69262. 2013
Optimizing Nasal Potential Difference Analysis for CFTR Modulator Development: Assessment of Ivacaftor in CF Subjects with the G551D-CFTR Mutation. 8:e66955. 2013
Targeting the Giant Cell Tumor Stromal Cell: Functional Characterization and a Novel Therapeutic Strategy. 8:e69101. 2013
Transient Combination Therapy Targeting the Immune Synapse Abrogates T Cell Responses and Prolongs Allograft Survival in Mice. 8:e69397. 2013
p16 Stimulates CDC42-Dependent Migration of Hepatocellular Carcinoma Cells. 8:e69389. 2013
High-Sensitivity C-Reactive Protein and Risk of Sepsis. 8:e69232. 2013
The Role of Cancer-Testis Antigens as Predictive and Prognostic Markers in Non-Small Cell Lung Cancer. 8:e67876. 2013
HIV-1 Autologous Antibody Neutralization Associates with Mother to Child Transmission. 8:e69274. 2013
Dual Regulatory Roles of Human AP-Endonuclease (APE1/Ref-1) in CDKN1A/p21 Expression. 8:e68467. 2013
Triglyceride/HDL Ratio as a Screening Tool for Predicting Success at Reducing Anti-Diabetic Medications Following Weight Loss. 8:e69285. 2013
Assessment of SLX4 Mutations in Hereditary Breast Cancers. 8. 2013
Comparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein Trimers. 8:e67484. 2013
An HIV-1 Envelope Glycoprotein Trimer with an Embedded IL-21 Domain Activates Human B Cells. 8:e67309. 2013
Application of Multiplexed Kinase Inhibitor Beads to Study Kinome Adaptations in Drug-Resistant Leukemia. 8:e66755. 2013
Discovery and Validation of a Prostate Cancer Genomic Classifier that Predicts Early Metastasis Following Radical Prostatectomy. 8:e66855. 2013
Exogenous Glucose Administration Impairs Glucose Tolerance and Pancreatic Insulin Secretion during Acute Sepsis in Non-Diabetic Mice. 8:e67716. 2013
Tumorspheres but Not Adherent Cells Derived from Retinoblastoma Tumors Are of Malignant Origin. 8:e63519. 2013
Two Distinct Categories of Focal Deletions in Cancer Genomes. 8:e66264. 2013
Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry. 8:e67306. 2013
Markers of Celiac Disease and Gluten Sensitivity in Children with Autism. 8:e66155. 2013
Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts. 8:e66371. 2013
Glutamine Supplementation Alleviates Vasculopathy and Corrects Metabolic Profile in an In Vivo Model of Endothelial Cell Dysfunction. 8:e65458. 2013
Fibulin-2 Is a Driver of Malignant Progression in Lung Adenocarcinoma. 8:e67054. 2013
A Role for Uric Acid and the Nalp3 Inflammasome in Antiphospholipid Antibody-Induced IL-1β Production by Human First Trimester Trophoblast. 8:e65237. 2013
Caregiver Evaluation of the Quality of End-Of-Life Care (CEQUEL) Scale: The Caregiver's Perception of Patient Care Near Death. 8:e66066. 2013
α-Lipoic Acid Antioxidant Treatment Limits Glaucoma-Related Retinal Ganglion Cell Death and Dysfunction. 8:e65389. 2013
A Multi-System Approach Assessing the Interaction of Anticonvulsants with P-gp. 8:e64854. 2013
Fatty Acid Synthase Is a Key Target in Multiple Essential Tumor Functions of Prostate Cancer: Uptake of Radiolabeled Acetate as a Predictor of the Targeted Therapy Outcome. 8:e64570. 2013
Pulsed Electromagnetic Fields Increased the Anti-Inflammatory Effect of A2A and A3 Adenosine Receptors in Human T/C-28a2 Chondrocytes and hFOB 1.19 Osteoblasts. 8. 2013
Stimulus-Evoked Calcium Transients in Somatosensory Cortex Are Temporarily Inhibited by a Nearby Microhemorrhage. 8:e65663. 2013
Age-Specific Gene Expression Signatures for Breast Tumors and Cross-Species Conserved Potential Cancer Progression Markers in Young Women. 8:e63204. 2013
Clinical Adjuvant Combinations Stimulate Potent B-Cell Responses In Vitro by Activating Dermal Dendritic Cells. 8:e63785. 2013
In silico Driven Redesign of a Clinically Relevant Antibody for the Treatment of GD2 Positive Tumors. 8:e63359. 2013
Gold Nanoparticle Delivery of Modified CpG Stimulates Macrophages and Inhibits Tumor Growth for Enhanced Immunotherapy. 8:e63550. 2013
A DTI-Based Template-Free Cortical Connectome Study of Brain Maturation. 8:e63310. 2013
Increased Tc22 and Treg/CD8 Ratio Contribute to Aggressive Growth of Transplant Associated Squamous Cell Carcinoma. 8:e62154. 2013
Variability of HIV-1 Genomes among Children and Adolescents from São Paulo, Brazil. 8:e62552. 2013
A Novel Approach for Characterizing Microsatellite Instability in Cancer Cells. 8:e63056. 2013
Age-Specific Signatures of Glioblastoma at the Genomic, Genetic, and Epigenetic Levels. 8:e62982. 2013
Prominin 1/CD133 Endothelium Sustains Growth of Proneural Glioma. 8:e62150. 2013
Gastrointestinal Stromal Tumors, Somatic Mutations and Candidate Genetic Risk Variants. 8:e62119. 2013
Design and Initial Results of a Multi-Phase Randomized Trial of Ceftriaxone in Amyotrophic Lateral Sclerosis. 8:e61177. 2013
EZH2 Mutations Are Related to Low Blast Percentage in Bone Marrow and -7/del(7q) in De Novo Acute Myeloid Leukemia. 8:e61341. 2013
Genome-Wide RNAi Screening Identifies Genes Inhibiting the Migration of Glioblastoma Cells. 8:e61915. 2013
Recombinant Human Growth Hormone and Rosiglitazone for Abdominal Fat Accumulation in HIV-Infected Patients with Insulin Resistance: A Randomized, Double-Blind, Placebo-Controlled, Factorial Trial. 8:e61160. 2013
CD19 CAR-Targeted T Cells Induce Long-Term Remission and B Cell Aplasia in an Immunocompetent Mouse Model of B Cell Acute Lymphoblastic Leukemia. 8:e61338. 2013
Whole Genome and Transcriptome Sequencing of a B3 Thymoma. 8. 2013
FXR Agonist INT-747 Upregulates DDAH Expression and Enhances Insulin Sensitivity in High-Salt Fed Dahl Rats. 8:e60653. 2013
Chimeric HIV-1 Envelope Glycoproteins with Potent Intrinsic Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Activity*. 8:e60126. 2013
Impaired Endothelial Progenitor Cell Mobilization and Dysfunctional Bone Marrow Stroma in Diabetes Mellitus. 8:e60357. 2013
Derivation of Multivariate Syndromic Outcome Metrics for Consistent Testing across Multiple Models of Cervical Spinal Cord Injury in Rats. 8:e59712. 2013
A Synergetic Screening Approach with Companion Effector for Combination Therapy: Application to Retinoblastoma. 8:e59156. 2013
Phase II Study Evaluating 2 Dosing Schedules of Oral Foretinib (GSK1363089), cMET/VEGFR2 Inhibitor, in Patients with Metastatic Gastric Cancer. 8:e54014. 2013
United States Acculturation and Cancer Patients' End-of-Life Care. 8:e58663. 2013
Emergence and Diversification of Dengue 2 Cosmopolitan Genotype in Pakistan, 2011. 8:e56391. 2013
Ablation of BRaf Impairs Neuronal Differentiation in the Postnatal Hippocampus and Cerebellum. 8:e58259. 2013
Fmr1 Transcript Isoforms: Association with Polyribosomes; Regional and Developmental Expression in Mouse Brain. 8:e58296. 2013
Long-Term Post-Stroke Changes Include Myelin Loss, Specific Deficits in Sensory and Motor Behaviors and Complex Cognitive Impairment Detected Using Active Place Avoidance. 8:e57503. 2013
Children's Medicines in Tanzania: A National Survey of Administration Practices and Preferences. 8:e58303. 2013
Targeted Deletion of Fibrinogen Like Protein 1 Reveals a Novel Role in Energy Substrate Utilization. 8:e58084. 2013
Effect of Linezolid on Clinical Severity and Pulmonary Cytokines in a Murine Model of Influenza A and Staphylococcus aureus Coinfection. 8:e57483. 2013
CD57 Expression and Cytokine Production by T Cells in Lesional and Unaffected Skin from Patients with Psoriasis. 8:e52144. 2013
Cell-Type-Specific Predictive Network Yields Novel Insights into Mouse Embryonic Stem Cell Self-Renewal and Cell Fate. 8:e56810. 2013
Early and Efficient Detection of Mycobacterium tuberculosis in Sputum by Microscopic Observation of Broth Cultures. 8:e57527. 2013
Action Initiation in the Human Dorsal Anterior Cingulate Cortex. 8:e55247. 2013
Detection of Amyloid Plaques Targeted by Bifunctional USPIO in Alzheimer's Disease Transgenic Mice Using Magnetic Resonance Microimaging. 8:e57097. 2013
NHE isoform switching and KChIP2 upregulation in aging porcine atria. 8:e82951. 2013
Identification of Special AT-Rich Sequence Binding Protein 1 as a Novel Tumor Antigen Recognized by CD8⁺ T Cells: Implication for Cancer Immunotherapy. 8:e56730. 2013
Adenovirus-Based Vaccine with Epitopes Incorporated in Novel Fiber Sites to Induce Protective Immunity against Pseudomonas aeruginosa. 8:e56996. 2013
High-Fidelity Tissue Engineering of Patient-Specific Auricles for Reconstruction of Pediatric Microtia and Other Auricular Deformities. 8:e56506. 2013
N-3 Fatty Acid Rich Triglyceride Emulsions Are Neuroprotective after Cerebral Hypoxic-Ischemic Injury in Neonatal Mice. 8:e56233. 2013
Functional Pathway Analysis Using SCNP of FLT3 Receptor Pathway Deregulation in AML Provides Prognostic Information Independent from Mutational Status. 8:e56714. 2013
Latitudinal Variations in Seasonal Activity of Influenza and Respiratory Syncytial Virus (RSV): A Global Comparative Review. 8:e54445. 2013
Proton Pump Inhibitor Use in the U.S. Ambulatory Setting, 2002-2009. 8:e56060. 2013
Intravenous tPA Therapy Does Not Worsen Acute Intracerebral Hemorrhage in Mice. 8. 2013
Candidate Sequence Variants and Fetal Hemoglobin in Children with Sickle Cell Disease Treated with Hydroxyurea. 8:e55709. 2013
The Quiescin Sulfhydryl Oxidase (hQSOX1b) Tunes the Expression of Resistin-Like Molecule Alpha (RELM-α or mFIZZ1) in a Wheat Germ Cell-Free Extract. 8:e55621. 2013
Accumulation of Intraneuronal β-Amyloid 42 Peptides Is Associated with Early Changes in Microtubule-Associated Protein 2 in Neurites and Synapses. 8:e51965. 2013
Genetic and Pharmacological Targeting of CSF-1/CSF-1R Inhibits Tumor-Associated Macrophages and Impairs BRAF-Induced Thyroid Cancer Progression. 8:e54302. 2013
Understanding the Potential Impact of a Combination HIV Prevention Intervention in a Hyper-Endemic Community. 8:e54575. 2013
A Virtual Retina for Studying Population Coding. 8:e53363. 2013
A Homogeneous, High-Throughput Assay for Phosphatidylinositol 5-Phosphate 4-Kinase with a Novel, Rapid Substrate Preparation. 8:e54127. 2013
Variability of Inducible Expression across the Hematopoietic System of Tetracycline Transactivator Transgenic Mice. 8:e54009. 2013
Human Embryonic Stem Cell Derived Mesenchymal Progenitors Express Cardiac Markers but Do Not Form Contractile Cardiomyocytes. 8. 2013
Long-Term In Vivo Imaging of Multiple Organs at the Single Cell Level. 8:e52087. 2013
A Critical Regulatory Role for Macrophage Migration Inhibitory Factor in Hyperoxia-Induced Injury in the Developing Murine Lung. 8. 2013
The impact of insurance status on the outcomes after aneurysmal subarachnoid hemorrhage.. 8:e78047. 2013
In Vivo Imaging Enables High Resolution Preclinical Trials on Patients' Leukemia Cells Growing in Mice. 7:e52798. 2012
Depressive Symptoms and Cardiovascular Health by the American Heart Association's Definition in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study. 7:e52771. 2012
How Have We Diagnosed Early-Stage Lung Cancer without Radiographic Screening? A Contemporary Single-Center Experience. 7:e52313. 2012
Differential Expression of CD96 Surface Molecule Represents CD8⁺T Cells with Dissimilar Effector Function during HIV-1 Infection. 7:e51696. 2012
Associations between Antibodies to a Panel of Plasmodium falciparum Specific Antigens and Response to Sub-Optimal Antimalarial Therapy in Kampala, Uganda. 7:e52571. 2012
MR Imaging Features of Gadofluorine-Labeled Matrix-Associated Stem Cell Implants in Cartilage Defects. 7:e49971. 2012
Reduced Proficiency in Homologous Recombination Underlies the High Sensitivity of Embryonal Carcinoma Testicular Germ Cell Tumors to Cisplatin and Poly (ADP-Ribose) Polymerase Inhibition. 7:e51563. 2012
Oligo- and Polymetastatic Progression in Lung Metastasis(es) Patients Is Associated with Specific MicroRNAs. 7:e50141. 2012
Histone Demethylase Jumonji D3 (JMJD3) as a Tumor Suppressor by Regulating p53 Protein Nuclear Stabilization. 7:e51407. 2012
A Synthetic Form of Frizzled 8-Associated Antiproliferative Factor Enhances p53 Stability through USP2a and MDM2. 7:e50392. 2012
Exome sequencing of only seven Qataris identifies potentially deleterious variants in the Qatari population.. 7:e47614. 2012
G-cimp status prediction of glioblastoma samples using mRNA expression data.. 7:e47839. 2012
Immunohistochemical detection of MYC-driven diffuse large B-cell lymphomas.. 7:e33813. 2012
Bifidobacterium breve with α-Linolenic Acid and Linoleic Acid Alters Fatty Acid Metabolism in the Maternal Separation Model of Irritable Bowel Syndrome. 7:e48159. 2012
CD4+ Cells Regulate Fibrosis and Lymphangiogenesis in Response to Lymphatic Fluid Stasis. 7:e49940. 2012
Dysregulation of IRP1-Mediated Iron Metabolism Causes Gamma Ray-specific Radioresistance in Leukemia Cells. 7:e48841. 2012
Somatic Mutations of PIK3R1 Promote Gliomagenesis. 7:e49466. 2012
Simultaneous Detection and Differentiation of Human Papillomavirus Genotypes 6, 11, 16 and 18 by AllGlo Quadruplex Quantitative PCR. 7:e48972. 2012
Caprylic Triglyceride as a Novel Therapeutic Approach to Effectively Improve the Performance and Attenuate the Symptoms Due to the Motor Neuron Loss in ALS Disease. 7:e49191. 2012
The Relative Influences of Phosphometabolites and pH on Action Potential Morphology during Myocardial Reperfusion: A Simulation Study. 7:e47117. 2012
Pregnancy Induces Transcriptional Activation of the Peripheral Innate Immune System and Increases Oxidative DNA Damage among Healthy Third Trimester Pregnant Women. 7:e46736. 2012
Chronic Medical Conditions and Risk of Sepsis. 7:e48307. 2012
BCL2A1a Over-Expression in Murine Hematopoietic Stem and Progenitor Cells Decreases Apoptosis and Results in Hematopoietic Transformation. 7:e48267. 2012
Utility of a PI3K/mTOR Inhibitor (NVP-BEZ235) for Thyroid Cancer Therapy. 7:e46726. 2012
Computational Modeling Reveals Dendritic Origins of GABAA-Mediated Excitation in CA1 Pyramidal Neurons. 7. 2012
Efficiency of Immunotoxin Cytotoxicity Is Modulated by the Intracellular Itinerary. 7:e47320. 2012
Autoantibodies Produced at the Site of Tissue Damage Provide Evidence of Humoral Autoimmunity in Inclusion Body Myositis. 7:e46709. 2012
Regulation of a Vascular Plexus by gata4 Is Mediated in Zebrafish through the Chemokine sdf1a. 7:e46844. 2012
AZD1480 Blocks Growth and Tumorigenesis of RET- Activated Thyroid Cancer Cell Lines. 7:e46869. 2012
Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy. 7:e46191. 2012
A High Degree of LINE-1 Hypomethylation Is a Unique Feature of Early-Onset Colorectal Cancer. 7:e45357. 2012
Age-Related Expansion of Tim-3 Expressing T Cells in Vertically HIV-1 Infected Children. 7:e45733. 2012
Extended Spectrum Beta-Lactamase-Producing Enterobacteriaceae in International Travelers and Non-Travelers in New York City. 7:e45141. 2012
Identification of Prostate-Specific G-Protein Coupled Receptor as a Tumor Antigen Recognized by CD8⁺ T Cells for Cancer Immunotherapy. 7:e45756. 2012
Combined, Sequential Intravenous and Intra-Arterial Chemotherapy (Bridge Chemotherapy) for Young Infants with Retinoblastoma. 7:e44322. 2012
Human Lung Cancer Cells Grown in an Ex Vivo 3D Lung Model Produce Matrix Metalloproteinases Not Produced in 2D Culture. 7. 2012
Quantitative Analysis of Monocyte Subpopulations in Murine Atherosclerotic Plaques by Multiphoton Microscopy. 7:e44823. 2012
An Integrated Genomic and Expression Analysis of 7q Deletion in Splenic Marginal Zone Lymphoma. 7:e44997. 2012
Graft versus Host Disease in the Bone Marrow, Liver and Thymus Humanized Mouse Model. 7:e44664. 2012
Complex Structure of Engineered Modular Domains Defining Molecular Interaction between ICAM-1 and Integrin LFA-1. 7:e44124. 2012
Early Reduction of Microglia Activation by Irradiation in a Model of Chronic Glaucoma. 7:e43602. 2012
A comparison of EGFR mutation testing methods in lung carcinoma: Direct sequencing, real-time PCR and immunohistochemistry. 7:e43842. 2012
Imaging characteristics, tissue distribution, and spread of a novel oncolytic vaccinia virus carrying the human sodium iodide symporter. 7:e41647. 2012
Comparison of 6q25 breast cancer hits from Asian and European genome wide association studies in the Breast Cancer Association consortium (BCAC). 7:e42380. 2012
Human endogenous retrovirus expression is inversely associated with chronic immune activation in HIV-1 infection. 7:e41021. 2012
Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits. 7:e42756. 2012
GLI2 regulates TGF-β1 in human CD4+ T cells: Implications in cancer and HIV pathogenesis. 7:e40874. 2012
Regulation of nuclear factor κB (NF-κB) transcriptional activity via p65 acetylation by the chaperonin containing TCP1 (CCT). 7:e42020. 2012
Development of a high-throughput assay for identifying inhibitors of TBK1 and IKKε. 7:e41494. 2012
Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation. 7:e41865. 2012
Inflammation drives dysbiosis and bacterial invasion in murine models of ileal Crohn's Disease. 7:e41594. 2012
Activation of soluble adenylyl cyclase protects against secretagogue stimulated zymogen activation in rat pancreaic acinar cells. 7:e41320. 2012
Multi-center evaluation of post-operative morbidity and mortality after optimal cytoreductive surgery for advanced ovarian cancer. 7:e39415. 2012
Comparison of wtc dust size on macrophage inflammatory cytokine release in vivo and in vitro. 7:e40016. 2012
Clinical application of cine-MRI in the visual assessment of mitral regurgitation compared to echocardiography and cardiac catheterization. 7:e40491. 2012
Genome-wide detection of genes targeted by Non-Ig somatic hypermutation in lymphoma. 7:e40332. 2012
Mouse transgenesis in a single locus with independent regulation for multiple fluorophores. 7:e40511. 2012
Four loci explain 83% of size variation in the horse. 7:e39929. 2012
Limitations of the human reference genome for personalized genomics. 7:e40294. 2012
Impact of combined mTOR and MEK inhibition in uveal melanoma is driven by tumor genotype. 7:e40439. 2012
A novel survival-based tissue microarray of pancreatic cancer validates muc1 and mesothelin as biomarkers. 7:e40157. 2012
Masstrix reloaded: Combined analysis and visualization of tran-scriptome and metabolome data. 7. 2012
Tim-3 negatively regulates cytotoxicity in exhausted CD8⁺T cells in HIV infection. 7:e40146. 2012
Absence of Ca²⁺-induced mitochondrial permeability transition but presence of bongkrekate-sensitive nucleotide exchange in C. crangon and P. serratus. 7:e39839. 2012
Breast cancer risk and 6q22.33: Combined results from breast cancer association consortium and consortium of investigators on modifiers of brca1/2. 7:e35706. 2012
Influence of HAART on alternative reading frame immune responses over the course of HIV-1 infection. 7:e39311. 2012
Radiation impairs perineural invasion by modulating the nerve microenvironment. 7:e39925. 2012
Γ-H2AX kinetics as a novel approach to high content screening for small molecule radiosensitizers. 7:e38465. 2012
Body fat free mass is associated with the serum metabolite profile in a population-based study. 7:e40009. 2012
Phase II trial of concurrent sunitinib and image-guided radiotherapy for oligometastases. 7:e36979. 2012
Characterization of Plasmodium falciparum Adenylyl Cyclase-β and its role in Erythrocytic stage parasites. 7:e39769. 2012
Fast, automated implementation of temporally precise blind deconvolution of multiphasic excitatory postsynaptic currents. 7:e38198. 2012
Line-scanning particle image velocimetry: An optical approach for quantifying a wide range of blood flow speeds in live animals. 7:e38590. 2012
Statistics of weighted brain networks reveal hierarchical organization and gaussian degree distribution. 7:e35029. 2012
Untargeted plasma metabolite profiling reveals the broad systemic consequences of xanthine oxidoreductase inactivation in mice. 7:e37149. 2012
DNA fragmentation simulation method (FSM) and fragment size matching improve aCGH performance of FFPE tissues. 7:e38881. 2012
Host genes related to Paneth cells and xenobiotic metabolism are associated with shifts in human ileum-associated microbial composition. 7:e30044. 2012
A BAX/BAK and cyclophilin D-independent intrinsic apoptosis pathway. 7:e37782. 2012
Mesenchymal cell interaction with ovarian cancer cells triggers pro-metastatic properties. 7:e38340. 2012
Multiple SNPs in intron 41 of thyroglobulin gene are associated with autoimmune thyroid disease in the Japanese population. 7:e37501. 2012
M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection. 7. 2012
Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) γ activators and Pan-PPAR partial agonists. 7:e36297. 2012
Innate immune response of human Plasmacytoid dendritic cells to poxvirus infection is subverted by vaccinia E3 via its Z-DNA/RNA binding domain. 7:e36823. 2012
The role of TNF-α in mice with type 1- and 2- diabetes. 7:e33254. 2012
Loss of the urothelial differentiation marker FOXA1 is associated with high grade, late stage bladder cancer and increased tumor proliferation. 7. 2012
Cardiomyopathy and response to enzyme replacement therapy in a male mouse model for fabry disease. 7:e33743. 2012
Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders. 7. 2012
Concordant signaling pathways produced by pesticide exposure in mice correspond to pathways identified in human parkinson's disease. 7:e36191. 2012
Functional characterization of circulating tumor cells with a prostate-cancer-specific microfluidic device. 7:e35976. 2012
Shh signaling from the nucleus pulposus is required for the postnatal growth and differentiation of the mouse intervertebral disc. 7:e35944. 2012
Ophthalmic artery chemosurgery for less advanced intraocular retinoblastoma: Five year review. 7:e34120. 2012
Assigning backbone NMR resonances for full length tau isoforms: Efficient compromise between manual assignments and reduced dimensionality. 7:e34679. 2012
Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screening. 7:e34414. 2012
Jc virus t-antigen regulates glucose metabolic pathways in brain tumor cells. 7. 2012
Repertoire enhancement with adoptively transferred female lymphocytes controls the growth of pre-implanted murine prostate cancer. 7:e35222. 2012
Host immune transcriptional profiles reflect the variability in clinical disease manifestations in patients with staphylococcus aureus infections. 7:e34390. 2012
Changes in prefrontal-limbic function in major depression after 15 months of long-term psychotherapy. 7:e33745. 2012
Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients. 7:e32345. 2012
Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: Relationship to HER2/neu expression in human and mouse. 7:e33421. 2012
Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors. 7:e34354. 2012
Acute histologic chorioamnionitis at term: Nearly always noninfectious. 7:e31819. 2012
Normalization of the lymph node T cell stromal microenvironment in lpr/lpr mice is associated with SU5416-induced reduction in autoantibodies. 7:e32828. 2012
Intentional weight loss and dose reductions of anti-diabetic medications - a retrospective cohort study. 7:e32395. 2012
Interleukin-1 stimulates ADAM17 through a mechanism independent of its cytoplasmic domain or phosphorylation at threonine 735. 7. 2012
The effect of the visual context in the recognition of symbolic gestures. 7:e29644. 2012
Quantitative modeling of Cerenkov light production efficiency from medical radionuclides. 7:e31402. 2012
Improved control of tuberculosis and activation of macrophages in mice lacking protein kinase R. 7:e30512. 2012
Towards the "baby connectome": Mapping the structural connectivity of the newborn brain. 7:e31029. 2012
Transcriptional analysis of shewanella oneidensis MR-1 with an electrode compared to Fe(III)citrate or oxygen as terminal electron acceptor. 7:e30827. 2012
Novel use of surveillance data to detect HIV-infected persons with sustained high viral load and durable virologic suppression in New York City. 7:e29679. 2012
Transcription factor FoxO1 is essential for enamel biomineralization. 7:e30357. 2012
Novel strategy for selection of monoclonal antibodies against highly conserved antigens: Phage library panning against ephrin-B2 displayed on yeast. 7:e30680. 2012
Circulating angiopoietin-2 as a biomarker in ANCA-associated vasculitis. 7:e30197. 2012
Association of differentiation state of CD4+ T cells and disease progression in HIV-1 perinatally infected children. 7:e29154. 2012
Protein phosphatase 2A mediates dormancy of glioblastoma multiforme-derived tumor stem-like cells during hypoxia. 7:e30059. 2012
Intra- and inter-tumor heterogeneity of BRAF V600Emutations in primary and metastatic melanoma. 7:e29336. 2012
Copy number variation analysis of matched ovarian primary tumors and peritoneal metastasis. 6:e28561. 2011
Socioeconomic status and incident type 2 diabetes mellitus: Data from the women's health study. 6:e27670. 2011
Endemic acinetobacter baumannii in a New York hospital. 6:e28566. 2011
A brain region-specific predictive gene map for autism derived by profiling a reference gene set. 6:e28431. 2011
Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense. 6:e28149. 2011
SHIV-162P3 infection of rhesus macaques given maraviroc gel vaginally does not involve resistant viruses. 6. 2011
Novel Retinoic Acid Receptor Alpha Agonists for Treatment of Kidney Disease. 6:e27945. 2011
Endoplasmic reticulum remodeling tunes IP3-dependent Ca2+ release sensitivity. 6:e27928. 2011
Fitness conferred by BCR-ABL kinase domain mutations determines the risk of pre-existing resistance in chronic myeloid leukemia. 6:e27682. 2011
Stat3 mediates expression of autotaxin in breast cancer. 6:e27851. 2011
Crosstalk between ROS homeostasis and secondary metabolism in s. natalensis atcc 27448: Modulation of pimaricin production by intracellular ros. 6:e27472. 2011
An Inter-Laboratory validation of a real time PCR assay to measure host excretion of bacterial pathogens, particularly of Mycobacterium bovis. 6:e27369. 2011
Serum microRNA expression profile distinguishes enterovirus 71 and coxsackievirus 16 infections in patients with hand-foot-and-mouth disease. 6:e27071. 2011
Excess circulating alternatively activated myeloid (M2) cells accelerate ALS progression while inhibiting experimental autoimmune encephalomyelitis. 6:e26921. 2011
An in vivo platform for tumor biomarker assessment. 6:e26722. 2011
C-kit-mediated functional positioning of stem cells to their niches is essential for maintenance and regeneration of adult hematopoiesis. 6:e26918. 2011
Cortical microhemorrhages cause local inflammation but do not trigger widespread dendrite degeneration. 6:e26612. 2011
Purinergic signaling induces cyclooxygenase-1-dependent prostanoid synthesis in microglia: Roles in the outcome of excitotoxic brain injury. 6:e25916. 2011
A system for performing high throughput assays of synaptic function. 6:e25999. 2011
Rem2-targeted shRNAs reduce frequency of miniature excitatory postsynaptic currents without altering voltage-gated Ca 2+ currents. 6:e25741. 2011
A time-series method for automated measurement of changes in mitotic and interphase duration from time-lapse movies. 6:e25511. 2011
Transgene excision has no impact on in vivo integration of human iPS derived neural precursors. 6:e24687. 2011
The wiring economy principle: Connectivity determines anatomy in the human brain. 6:e14832. 2011
Altered development of NKT cells, γδ T cells, CD8 T cells and NK cells in a PLZF deficient patient. 6:e24441. 2011
SMURF1 amplification promotes invasiveness in pancreatic cancer. 6:e23924. 2011
Loss of cytoplasmic CDK1 predicts poor survival in human lung cancer and confers chemotherapeutic resistance. 6:e23849. 2011
The Candida albicans Ku70 modulates telomere length and structure by regulating both telomerase and recombination. 6:e23732. 2011
Adherence of pharmaceutical advertisements in medical journals to FDA guidelines and content for safe prescribing. 6:e23336. 2011
The accuracy of the electrocardiogram during exercise stress test based on heart size. 6:e23044. 2011
Hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network. 6:e22649. 2011
A phase iia randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade RAD5 HIV-1 vaccine boost in healthy adults (HVTN204). 6:e21225. 2011
Oral microbiome profiles: 16s rRNA pyrosequencing and microarray assay comparison. 6:e22788. 2011
Biologic phenotyping of the human small airway epithelial response to cigarette smoking. 6:e22798. 2011
Frequency domain analysis reveals external periodic fluctuations can generate sustained p53 oscillation. 6:e22852. 2011
Imaging of alkaline phosphatase activity in bone tissue. 6:e22608. 2011
An integrative view of mechanisms underlying generalized Apike-And-Wave epileptic seizures and its implication on optimal therapeutic treatments. 6:e22440. 2011
Catalytic and non-catalytic roles for the mono-ADP-ribosyltransferase arr in the mycobacterial DNA damage response. 6:e21807. 2011
P16 INK4a positively regulates cyclin D1 and E2F1 through negative control of auf1. 6:e21111. 2011
Immunodominance of HIV-1 specific CD8+ T-cell responses is related to disease progression rate in vertically infected adolescents. 6:e21135. 2011
Out-of-frame T cell receptor beta transcripts are eliminated by multiple pathways In Vivo. 6:e21627. 2011
Rex shunt preoperative imaging: Diagnostic capability of imaging modalities. 6:e22222. 2011
War and bereavement: Consequences for mental and physical distress. 6:e22140. 2011
Differences between human plasma and serum metabolite profiles. 6:e21230. 2011
Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation. 6:e21611. 2011
Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression. 6:e20605. 2011
Detection of intra-tumor self antigen recognition during melanoma tumor progression in mice using advanced multimode confocal/two photon microscope. 6:e21214. 2011
MicroRNA expression and clinical outcome of small cell lung cancer. 6. 2011
Mitochondrial ceramide-rich macrodomains functionalize bax upon irradiation. 6:e19783. 2011
Human endogenous retrovirus K106 (HERV-k106) was infectious after the emergence of anatomically modern humans. 6:e20234. 2011
A tri-marker proliferation index predicts biochemical recurrence after surgery for prostate cancer. 6:e20293. 2011
Estimating survival in patients with operable skeletal metastases: An application of a Bayesian belief network. 6:e19956. 2011
Multizone paper platform for 3D cell cultures. 6:e18940. 2011
Bacterial transmembrane proteins that lack N-terminal signal sequences. 6:e19421. 2011
The human airway epithelial basal cell transcriptome. 6:e18378. 2011
Resistance of renal cell carcinoma to sorafenib is mediated by potentially reversible gene expression. 6:e19144. 2011
Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice. 6. 2011
Th17 cells and activated dendritic cells are increased in vitiligo lesions. 6:e18907. 2011
Assessment of cardiovascular fibrosis using novel fluorescent probes. 6:e19097. 2011
Multiplexed immunoassay panel identifies novel CSF biomarkers for alzheimer's disease diagnosis and prognosis. 6:e18850. 2011
Down-regulation of the canonical wnt β-catenin pathway in the airway epithelium of healthy smokers and smokers with COPD. 6:e14793. 2011
Inhibition of anaplastic lymphoma kinase (ALK) activity provides a therapeutic approach for CLTC-ALK-positive human diffuse large B cell lymphomas. 6:e18436. 2011
Dopaminergic Neuronal loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2. 6:e18568. 2011
A computational framework discovers new copy number variants with functional importance. 6:e17539. 2011
Multiple cancer/testis antigens are preferentially expressed in hormone-receptor negative and high-grade breast cancers. 6:e17876. 2011
Evaluating research and impact: A bibliometric analysis of research by the NIH/NIAID HIV/AIDS clinical trials networks. 6:e17428. 2011
Lipid nanocapsules loaded with Rhenium-188 reduce tumor progression in a rat hepatocellular carcinoma model. 6:e16926. 2011
MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors. 6:e17449. 2011
Phosphodiesterase 4 inhibition reduces innate immunity and improves isoniazid clearance of Mycobacterium tuberculosis in the lungs of infected mice. 6:e17091. 2011
Critical role of neuropeptides B/W receptor 1 signaling in social behavior and fear memory. 6:e16972. 2011
Mechanisms of lymphatic regeneration after tissue transfer. 6:e17201. 2011
Prediction of associations between microRNAs and gene expression in glioma biology. 6:e14681. 2011
Rituximab therapy reduces organ-specific T cell responses and ameliorates experimental autoimmune encephalomyelitis. 6:e17103. 2011
Discovery of novel human breast cancer micrornas from deep sequencing data by analysis of pri-microrna secondary structures. 6:e16403. 2011
A one-dimensional continuum elastic model for membrane-embedded gramicidin dimer dissociation. 6:e15563. 2011
The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter. 6:e16350. 2011
Optimizing tactics for use of the U.S. antiviral strategic national stockpile for pandemic influenza. 6. 2011
DNA methylation of the first exon is tightly linked to transcriptional silencing. 6:e14524. 2011
Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-Deficient PDGF-driven murine glioblastoma. 6:e14545. 2011
Identification and Validation of Novel Cerebrospinal Fluid Biomarkers for Staging Early Alzheimer's Disease. 6:e16032. 2011
Aptamer-based multiplexed proteomic technology for biomarker discovery. 5:e15004. 2010
O-Glycosylation regulates ubiquitination and degradation of the anti-inflammatory protein A20 to accelerate atherosclerosis in diabetic ApoE-null mice. 5:e14240. 2010
Duplication of the slit3 locus on 5q35.1 predisposes to major depressive disorder. 5:e15463. 2010
Improving a mother to child HIV transmission programme through health system redesign: Quality improvement, protocol adjustment and resource addition. 5:e13891. 2010
Metabolic footprint of diabetes: A multiplatform metabolomics study in an epidemiological setting. 5:e13953. 2010
Notch and MAML-1 Complexation do not detectably alter the DNA binding specificity of the transcription factor CSL. 5:e15034. 2010
A phase II trial of sorafenib in metastatic melanoma with tissue correlates. 5:e15588. 2010
Adaptation of group A Streptococcus to human amniotic fluid. 5. 2010
Altered auditory BOLD response to conspecific birdsong in zebra finches with stuttered syllables. 5:e14415. 2010
An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma. 5:e9863. 2010
Genome-wide screen for Mycobacterium tuberculosis genes that regulate host immunity. 5:e15120. 2010
Large-scale discovery and characterization of protein regulatory motifs in eukaryotes. 5:e14444. 2010
MicroRNA-Related Cofilin Abnormality in Alzheimer's Disease. 5:e15546. 2010
Prolonged Application of High Fluid Shear to Chondrocytes Recapitulates Gene Expression Profiles Associated with Osteoarthritis. 5:e15174. 2010
Simultaneous analysis of multiple mycobacterium tuberculosis knockdown mutants in vitro and in vivo. 5:e15667. 2010
The complete chloroplast genome sequence of date palm (Phoenix dactylifera L.).. 5:e12762. 2010
A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-α and MIP1-β, a lack of IL-17, and a Th1-bias in males. 5:e15412. 2010
A new mouse model to explore therapies for preeclampsia. 5:e13663. 2010
Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown. 5:e13568. 2010
Identification of De Novo copy number variants associated with human disorders of sexual development. 5:e15392. 2010
MicroRNA-integrated and network-embedded gene selection with diffusion distance. 5:e13748. 2010
Nitrate respiration protects hypoxic Mycobacterium tuberculosisagainst acid- and reactive nitrogen species stresses. 5:e13356. 2010
Phosphatidylinositol 5-phosphate links dehydration stress to the activity of ARABIDOPSIS TRITHORAX-LIKE factor ATX1. 5:e13396. 2010
Splice isoforms of the polyglutamine disease protein ataxin-3 exhibit similar enzymatic yet different aggregation properties. 5:e13695. 2010
Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition. 5:e12707. 2010
Alphavirus replicon particles expressing TRP-2 provide potent therapeutic effect on melanoma through activation of humoral and cellular immunity. 5:1-8. 2010
Clostridium perfringens epsilon toxin targets granule cells in the mouse cerebellum and stimulates glutamate release. 5. 2010
Frequent MAGE mutations in human melanoma. 5:1-7. 2010
Harnessing naturally occurring tumor immunity: A clinical vaccine trial in prostate cancer. 5:1-12. 2010
Human MicroRNA oncogenes and tumor suppressors show significantly different biological patterns: From functions to targets. 5:1-7. 2010
Induction of ER stress in macrophages of tuberculosis granulomas. 5:e12772. 2010
Skewed distribution of circulating activated natural killer T (NKT) cells in patients with common variable immunodeficiency disorders (CVID). 5:1-8. 2010
Cholesterol pathways affected by small molecules that decrease sterol levels in niemann-pick type C mutant cells. 5:e12788. 2010
Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease. 5. 2010
Endothelial membrane remodeling is obligate for anti-angiogenic radiosensitization during tumor radiosurgery. 5:e12310. 2010
Bayesian linkage analysis of categorical traits for arbitrary pedigree designs. 5:e12307. 2010
Deletion of Nhlh2 results in a defective torpor response and reduced beta adrenergic receptor expression in adipose tissue. 5:e12324. 2010
Portable, battery-operated, low-cost, bright field and fluorescence microscope. 5:e11890. 2010
Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer. 5. 2010
Integrative genome comparison of primary and metastatic melanomas. 5:e10770. 2010
Molecular targeting of carbonic anhydrase ix in mice with hypoxic HT29 colorectal tumor xenografts. 5:e10857. 2010
Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation. 5:e10436. 2010
Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin. 5:e10504. 2010
Genetic analysis of the early natural history of epithelial ovarian carcinoma. 5:e10358. 2010
A forward chemical screen in zebrafish identifies a retinoic acid derivative with receptor specificity. 5:e10004. 2010
Evaluation of the Psoriasis Transcriptome across Different Studies by Gene Set Enrichment Analysis (GSEA). 5:e10247. 2010
Rapid Progressing Allele HLA-B35 Px Restricted Anti-HIV-1 CD8+ T Cells Recognize Vestigial CTL Epitopes. 5:e10249. 2010
The onconeural antigen cdr2 is a novel APC/C target that acts in mitosis to regulate C-Myc target genes in mammalian tumor cells. 5:e10045. 2010
Clinically relevant characterization of lung adenocarcinoma subtypes based on cellular pathways: An international validation study. 5:e11712. 2010
Proinflammatory phenotype and increased caveolin-1 in alveolar macrophages with silenced CFTR mRNA. 5:e11004. 2010
Rates and reasons for early change of first HAART in HIV-1-infected patients in 7 sites throughout the Caribbean and Latin America. 5:e10490. 2010
The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways. 5:e9633. 2010
The shifting demographic landscape of pandemic influenza. 5:e9360. 2010
Prolonged graft survival in older recipient mice is determined by impaired effector T-cell but intact regulatory T-cell responses. 5:e9232. 2010
Measuring the pharmacodynamic effects of a novel Hsp90 inhibitor on HER2/ neu expression in mice using 89Zr-DFO-trastuzumab. 5:e8859. 2010
A phase II trial of the epothilone B analog ixabepilone (BMS-247550) in patients with metastatic melanoma. 5:e8714. 2010
Human CD4⁺ memory T cells can become CD4⁺IL-9 ⁺ T cells. 5:e8706. 2010
Prokayrotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis. 5:e8589. 2010
Intelligence in Williams Syndrome is related to STX1A, which encodes a component of the presynaptic SNARE complex.. 5:e10292. 2010
Cross Species Genomic Analysis Identifies a Mouse Model as Undifferentiated Pleomorphic Sarcoma/Malignant Fibrous Histiocytoma. 4:e8075. 2009
Down regulation of genes involved in T cell polarity and motility during the induction of heart allograft tolerance by allochimeric MHC I. 4:e8020. 2009
Long-term stability of visual pattern selective responses of monkey temporal lobe neurons. 4:e8222. 2009
Modulation of cell surface protein free thiols: A potential novel mechanism of action of the sesquiterpene lactone parthenolide. 4:e8115. 2009
Self-reported and actual beta-blocker prescribing for heart failure patients: Physician predictors. 4:e8522. 2009
Smoking is associated with shortened airway Cilia. 4:e8157. 2009
Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis. 4:e7955. 2009
Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations. 4:e7752. 2009
Origins of an intrinsic hippocampal EEG pattern. 4:e7761. 2009
Metabolomic profiling in LRRK2-related Parkinson's disease. 4:e7551. 2009
Enteric neural crest differentiation in ganglioneuromas implicates hedgehog signaling in peripheral neuroblastic tumor pathogenesis. 4:e7491. 2009
Physico-chemical evaluation of rationally designed melanins as novel nature-inspired radioprotectors. 4:e7229. 2009
Rhabdomyolysis in community acquired bacterial sepsis - A retrospective cohort study. 4:e7182. 2009
Empirical study of data sharing by authors publishing in PLoS journals. 4:e7078. 2009
Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders. 4:e7100. 2009
Comparison of the immunomodulatory properties of three probiotic strains of Lactobacilli using complex culture systems: Prediction for in vivo efficacy. 4:e7056. 2009
NAChRs mediate human embryonic stem cell-derived endothelial cells: Proliferation, apoptosis, and angiogenesis. 4:e7040. 2009
Activation of PyMT in β cells induces irreversible hyperplasia, but oncogene-dependent acinar cell carcinomas when activated in pancreatic progenitors. 4:e6932. 2009
Systems-level modeling of cancer-fibroblast interaction. 4:e6888. 2009
The influence of radiographic phenotype and smoking status on peripheral blood biomarker patterns in chronic obstructive pulmonary disease. 4:e6865. 2009
Identification of a human cyclin D1-derived peptide that induces human cytotoxic CD4 T cells. 4:e6730. 2009
Multiparameter phospho-flow analysis of lymphocytes in early rheumatoid arthritis: Implications for diagnosis and monitoring drug therapy. 4:e6703. 2009
A decreased frequency of regulatory T cells in patients with common variable immunodeficiency. 4:e6269. 2009
Transcriptome adaptation of group B Streptococcus to growth in human amniotic fluid. 4:e6114. 2009
Intragraft selection of the T cell receptor repertoire by class I MHC sequences in tolerant recipients. 4:e6076. 2009
p63 promotes cell survival through fatty acid synthase. 4:e5877. 2009
Tolerance to the neuron-specific paraneoplastic HuD antigen. 4:e5739. 2009
Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription. 4:e5757. 2009
Latherin: A surfactant protein of horse sweat and saliva. 4. 2009
Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo. 4:e5683. 2009
Challenges for routine health system data management in a large public programme to prevent mother-to-child HIV transmission in South Africa. 4:e5483. 2009
Enhanced monocyte response and decreased central memory T cells in children with invasive Staphylococcus aureus infections. 4:e5446. 2009
Uncovering the genetic landscape for multiple sleep-wake traits. 4:e5161. 2009
Qualitative and quantitative detection of Chlamydophila pneumoniae DNA in cerebrospinal fluid from multiple sclerosis patients and controls. 4:e5200. 2009
Pattern-selection based power analysis and discrimination of low- and high-grade myelodysplastic syndromes study using SNP arrays. 4:e5054. 2009
Real-time imaging of HIF-1α stabilization and degredation. 4:e5077. 2009
Genome-wide hypomethylation in head and neck cancer is more pronounced in HPV-negative tumors and is associated with genomic instability. 4:e4941. 2009
HIV-1 epidemic in the Caribbean is dominated by subtype B. 4:e4814. 2009
Imaging of lymph node micrometastases using an oncolytic herpes virus and [18F]FEAU PET. 4:e4789. 2009
Human T cell leukemia virus reactivation with progression of adult T-cell leukemia-lymphoma. 4:e4420. 2009
High CD8+ T cell activation marks a less differentiated HIV-1 specific CD8+ T cell response that is not altered by suppression of viral replication. 4. 2009
PECAM-independent thioglycollate peritonitis is associated with a locus on murine chromosome 2. 4:e4316. 2009
IGFBP3 colocalizes with and regulates hypocretin (orexin). 4:e4254. 2009
PEG minocycline-liposomes ameliorate CNS autoimmune disease. 4:e4151. 2009
PINK1 Defect Causes Mitochondrial Dysfunction, Proteasomal Deficit and a-Synuclein Aggregation in Cell Culture Models of Parkinson's Disease. 4:e4597. 2009
BRAF activation initiates but does not maintain invasive prostate adenocarcinoma. 3:e3949. 2008
Oncologic trogocytosis of an original stromal cells induces chemoresistance of ovarian tumours. 3:e3894. 2008
Non-natural and photo-reactive amino acids as biochemical probes of immune function. 3:e3938. 2008
Metabolic profiling reveals distinct variations linked to nicotine consumption in humans - First results from the KORA study. 3:e3863. 2008
Improving outcomes in infants of HIV-infected women in a developing country setting. 3:e3723. 2008
HIV-specific T-cells accumulate in the liver in HCV/HIV co-infection. 3:e3454. 2008
Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. 3:e3316. 2008
Somatic 'soluble' adenylyl cyclase isoforms are unaffected in Sacytm1Lex/Sacytm1Lex 'knockout' mice. 3:e3251. 2008
Functional copy-number alterations in cancer. 3:e3179. 2008
Breast tumor cells with P13K mutation or HER2 amplification are selectively addicted to Akt signaling. 3:e3065. 2008
Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth. 3:e2916. 2008
Meta-analysis of microarray studies reveals a novel hematopoietic progenitor cell signature and demonstrates feasibility of inter-platform data integration. 3:e2965. 2008
Principles of glomerular organization in the human olfactory bulb - Implications for odor processing. 3:e2640. 2008
Immunogenecity of modified alkane polymers is mediated through TLR1/2 activation. 3:e2438. 2008
A tissue biomarker panel predicting systemic progression after PSA recurrence post-definitive prostate cancer therapy. 3:e2318. 2008
Genital herpes has played a more important role than any other sexually transmitted infection in driving HIV prevalence in Africa. 3:e2230. 2008
Understanding the impact of male circumcision interventions on the spread of HIV in southern Africa. 3:e2212. 2008
Ionic mechanisms of endogenous bursting in CA3 hippocampal pyramidal neurons: A model study. 3:e2056. 2008
An integrative genomic and epigenomic approach for the study of transcriptional regulation. 3:e1882. 2008
Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP. 3:e1746. 2008
Ganglion cell adaptability: Does the coupling of horizontal cells play a role?. 3:e1714. 2008
Integration of gene dosage and gene expression in non-small cell lung cancer, identification of HSP90 as potential target. 3:e0001722. 2008
Mitogen-activated protein kinases regulate susceptibility to ventilator-induced lung injury. 3:e1601. 2008
Nucleoside analogue reverse transcriptase inhibitors differentially inhibit human LINE-1 retrotransposition. 3:e1547. 2008
Microbial patterns signaling via toll-like receptors 2 and 5 contribute to epithelial repair, growth and survival. 3:e1393. 2008
Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway. 2:e1337. 2007
The complete genome sequence and analysis of the epsilonproteobacterium Arcobacter butzleri. 2:e1358. 2007
Id1 restrains p21 expression to control endothelial progenitor cell formation. 2:e1338. 2007
Amyotrophic lateral sclerosis: An emerging era of collaboratie gene discovery. 2:e1254. 2007
Therapeutic strategy for acute spinal cord contusion injury: cell elimination combined with microsurgical intervention.. 2:e565. 2007
HIV-1/HSV-2 co-infected adults in early HIV-1 infection have elevated CD4+ T cell counts. 2:e1080. 2007
Optimal signal processing in small stochastic biochemical networks. 2:e1077. 2007
PET imaging of soluble yttrium-86-labeled carbon nanotubes in mice. 2:e907. 2007
Development of new mouse lung tumor models expressing EGFR T790M mutants associated with clinical resistance to kinase inhibitors. 2:e810. 2007
Simple sequence repeats provide a substrate for phenotypic variation in the Neurospora crassa circadian clock. 2:e795. 2007
Long-term impact of radiation on the stem cell and oligodendrocyte precursors in the brain. 2:e588. 2007
Ionizing radiation changes the electronic properties of melanin and enhances the growth of melanized fungi. 2:e457. 2007
Calculation of the free energy and cooperativity of protein folding. 2:e446. 2007
Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4. 2:e426. 2007
XSelective alpha-particle mediated depletion of tumor vasculature with vascular normalization. 2:e267. 2007
Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape. 2:e225. 2007
Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removal. 1:e102. 2006
Correction: Type 2 diabetes risk allele loci in the Qatari population (PLoS ONE (2016) 11:7 (e0156834) DOI: 10.1371/journal.pone.0156834). 11:e0161910. 2016
Correction: Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes. 11:e0160293. 2016
Elevation of non-classical (CD14^+/low CD16⁺⁺ ) monocytes is associated with increased albuminuria and urine TGF-β1in HIV-infected individuals on stable antiretroviral therapy. 11. 2016
Correction: Mitochondrial ceramide-rich macrodomains functionalize bax upon irradiation. 10:e0146210. 2015
Correction: Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice. 10. 2015
Correction: Folate receptor-α (FOLR1) expression and function in triple negative tumors. 10:e0127133. 2015
Correction: Continuing a cancer treatment despite tumor growth may be valuable: Sunitinib in renal cell carcinoma as example (PLoS ONE (2014) 9, 5 (e96316) DOI: 10.1371/journal.pone.0096316). 9. 2014
Correction: Simplification to abacavir/lamivudine + atazanavir maintains viral suppression and improves bone and renal biomarkers in ASSURE, a randomized, open label, non-inferiority trial (PLoS ONE (2014) 9, 5 (e96187) DOI: 10.1371/journal.pone.0096187). 9. 2014
Correction: Signaling role of prokineticin 2 on the estrous cycle of female mice (PLoS ONE (2014) 9, 3 (e90860) DOI:10.1371/journal.pone.0090860). 9. 2014
Correction: A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events (PLoS ONE (2014) 9, 1 (e87361) DOI: 10.1371/journal.pone.0087361). 9. 2014
Correction: Microfluidic generated EGF-Gradients induce chemokinesis of transplantable retinal progenitor cells via the JAK/STAT and PI3Kinase signaling pathways (PLoS ONE). 9. 2014
Correction: Oligo- and polymetastatic progression in lung metastasis(es) patients is associated with specific microRNAs (PLoS ONE). 8. 2013
Correction: Computational modeling reveals dendritic origins of GABA A-mediated excitation in CA1 pyramidal neurons (PLoS ONE). 8. 2013
Correction: CD4+ cells regulate fibrosis and lymphangiogenesis in response to lymphatic fluid stasis (PLoS ONE). 8. 2013
Correction: Graft versus host disease in the bone marrow, liver and thymus humanized mouse model. (PLoS ONE (2012) 7, 9 (e44664) DOI:10.1371/journal.pone. 0044664). 8. 2013
Very severe anemia and one year mortality outcome after hospitalization in Tanzanian children: A prospective cohort study 2019
An international consensus definition of the wish to hasten death and its related factors 2016
Hepatitis C virus viremic rate in the Middle East and North Africa: Systematic synthesis, meta-analyses, and meta-regressions 2017
Cost-effectiveness of adjunct non-pharmacological interventions for osteoarthritis of the knee 2017
Increased mortality in metal-on-metal versus non-metal-on-metal primary total hip arthroplasty at 10 years and longer follow-up: A systematic review and meta-analysis 2016
Hepatitis C virus epidemiology in Djibouti, Somalia, Sudan, and Yemen: Systematic review and meta-analysis 2016
Validation of the stop-bang questionnaire as a screening tool for obstructive sleep apnea among different populations: A systematic review and meta-Analysis 2015
Prevalence of prostate cancer clinical states and mortality in the United States: Estimates using a dynamic progression model 2015
Local anesthetic peripheral nerve block adjuvants for prolongation of analgesia: A systematic qualitative review 2015
The epidemiology of hepatitis C virus in the fertile crescent: Systematic review and meta-analysis 2015
The effectiveness of different interventions to promote poison prevention behaviours in households with children: A network meta-analysis 2015
Control group design, contamination and drop-out in exercise oncology trials: A systematic review 2015
The epidemiology of hepatitis C virus in the maghreb region: Systematic review and Meta-analyses 2015
Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function 2014
Influence of control group on effect size in trials of acupuncture for chronic pain: A secondary analysis of an individual patient data meta-analysis 2014
Genetic polymorphisms of XRCC1 and leukemia risk: A meta-analysis of 19 case-control studies 2013
Characteristics of Acupuncture Treatment Associated with Outcome: An Individual Patient Meta-Analysis of 17,922 Patients with Chronic Pain in Randomised Controlled Trials 2013
The effects of dietary intervention on HIV dyslipidaemia: A systematic review and meta-analysis 2012

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