PLoS ONE Journal

Overview

publication venue for

• Aberrant gene expression by Sertoli cells in infertile men with Sertoli cell-only syndrome.  14. 2019
• Developing a dynamic HIV transmission model for 6 U.S. cities: An evidence synthesis.  14. 2019
• Dynamic modelling of an ACADS genotype in fatty acid oxidation - Application of cellular models for the analysis of common genetic variants.  14. 2019
• Pharmacodynamic study of radium-223 in men with bone metastatic castration resistant prostate cancer.  14. 2019
• Herpes simplex virus type 1 epidemiology in Latin America and the Caribbean: Systematic review and meta-analytics.  14. 2019
• Optimizing the production and affinity purification of HIV-1 envelope glycoprotein SOSIP trimers from transiently transfected CHO cells.  14. 2019
• Retinoids induce antagonism between FOXO3A and FOXM1 transcription factors in human oral squamous cell carcinoma (OSCC) cells.  14. 2019
• The impact of bariatric surgery on asthma control differs among obese individuals with reported prior or current asthma, with or without metabolic syndrome.  14. 2019
• Validation of publicly-available software used in analyzing NGS data for HIV-1 drug resistance mutations and transmission networks in a Washington, DC, Cohort.  14. 2019
• A non-randomized trial to assess the safety, tolerability, and pharmacokinetics of posaconazole oral suspension in immunocompromised children with neutropenia.  14. 2019
• Genetic and epigenetic profiling of the infertile male.  14:e0214275. 2019
• An efficient and cost-effective method for purification of small sized DNAs and RNAs from human urine.  14:e0210813. 2019
• Community health workers trained to conduct verbal autopsies provide better mortality measures than existing surveillance: Results from a cross-sectional study in rural western Uganda.  14:e0211482. 2019
• PCSK9 loss-of-function variants and risk of infection and sepsis in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort.  14:e0210808. 2019
• Association of electroretinography with visual outcomes after ophthalmic artery chemosurgery for retinoblastoma in ICRb D and E eyes.  14. 2019
• Corneal nerve and endothelial cell damage in patients with transient ischemic attack and minor ischemic stroke.  14:e0213319. 2019
• Dengue and chikungunya seroprevalence among Qatari nationals and immigrants residing in Qatar.  14. 2019
• Effects of AM80 compared to AC261066 in a high fat diet mouse model of liver disease.  14. 2019
• Impact of CodY protein on metabolism, sporulation and virulence in Clostridioides difficile ribotype 027.  14. 2019
• Molecular characterization of viruses associated with encephalitis in São Paulo, Brazil.  14. 2019
• Revisiting aneuploidy profile of surgically retrieved spermatozoa by whole exome sequencing molecular karyotype.  14. 2019
• Increased Alzheimer’s risk during the menopause transition: A 3-year longitudinal brain imaging study.  13:e0207885. 2018
• Ablation of nasal-associated lymphoid tissue does not affect focal ischemic brain injury in mice.  13:e0205470. 2018
• Implementation of a novel continuous fetal Doppler (Moyo) improves quality of intrapartum fetal heart rate monitoring in a resource-limited tertiary hospital in Tanzania: An observational study.  13:e0205698. 2018
• Region-specific susceptibility change in cognitively impaired patients with diabetes mellitus.  13:e0205797. 2018
• Tissue engineering the human auricle by auricular chondrocyte-mesenchymal stem cell co-implantation.  13:e0202356. 2018
• Adult mortality trends in Qatar, 1989-2015: National population versus migrants.  13:e0203996. 2018
• Evaluation of surfactant proteins A, B, C, and D in articular cartilage, synovial membrane and synovial fluid of healthy as well as patients with osteoarthritis and rheumatoid arthritis.  13:e0203502. 2018
• Exome sequencing-based identification of novel type 2 diabetes risk allele loci in the Qatari population.  13:e0199837. 2018
• Integrating the skin and blood transcriptomes and serum proteome in hidradenitis suppurativa reveals complement dysregulation and a plasma cell signature.  13:e0203672. 2018
• An in-vivo pilot study into the effects of FDG-mNP in cancer in mice.  13:e0202482. 2018
• Comparison of two different methods of image analysis for the assessment of microglial activation in patients with multiple sclerosis using (R)-[N-methyl-carbon-11] PK11195.  13:e0201289. 2018
• Post-hospital mortality in children aged 2-12 years in Tanzania: A prospective cohort study.  13:e0202334. 2018
• Predicting death and lost to follow-up among adults initiating antiretroviral therapy in resource-limited settings: Derivation and external validation of a risk score in Haiti.  13:e0201945. 2018
• Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer.  13:e0199012. 2018
• The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis.  13:e0200486. 2018
• AR negative triple negative or “Quadruple Negative” breast cancers in African American women have an enriched basal and immune signature.  13:e0196909. 2018
• Anatomic measurements of cerebral venous sinuses in idiopathic intracranial hypertension patients.  13:e0196275. 2018
• Association of functional and structural social support with medication adherence among individuals treated for coronary heart disease risk factors: Findings from the REasons for Geographic and Racial Differences in Stroke (REGARDS) study.  13:e0198578. 2018
• Growth patterns of survivors of retinoblastoma treated with ophthalmic artery chemosurgery.  13:e0197052. 2018
• Impact of left ventricular diastolic function and survival in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement.  13:e0196031. 2018
• TMSOTf assisted synthesis of 2’-deoxy-2’-[¹⁸F] fluoro-β-D-arabinofuranosylcytosine ([¹⁸F] FAC).  13:e0196784. 2018
• Ten-year experience with ophthalmic artery chemosurgery: Ocular and recurrence-free survival.  13:e0197081. 2018
• Whole blood transcriptional profiles as a prognostic tool in complete and incomplete Kawasaki Disease.  13:e0197858. 2018
• Aspirin use and long-term rates of sepsis: A population-based cohort study.  13:e0194829. 2018
• Mild cognitive dysfunction of caregivers and its association with care recipients’ end-of-life plans and preferences.  13:e0196147. 2018
• Pharmacogenetic landscape of metabolic syndrome components drug response in Tunisia and comparison with worldwide populations.  13:e0194842. 2018
• Readmission prediction via deep contextual embedding of clinical concepts.  13:e0195024. 2018
• Temporal evolution of HIV sero-discordancy patterns among stable couples in sub-Saharan Africa.  13:e0196613. 2018
• Total retinal detachments due to retinoblastoma: Outcomes following intraarterial chemotherapy/ophthalmic artery chemosurgery.  13:e0195395. 2018
• A care bundle including antenatal corticosteroids reduces preterm infant mortality in Tanzania a low resource country.  13:e0193146. 2018
• Peripheral neuropathy in patients with multiple sclerosis.  13:e0193270. 2018
• Racial disparities in the prevalence and control of hypertension among a cohort of HIV-infected patients in the southeastern United States.  13:e0194940. 2018
• The influence of age, anthropometric and metabolic variables on LDIFLARE and corneal confocal microscopy in healthy individuals.  13:e0193452. 2018
• Why west? Comparisons of clinical, genetic and molecular features of infants with and without spasms.  13:e0193599. 2018
• Synthesis, stabilization, and characterization of the MR1 ligand precursor 5-amino-6-D-ribitylaminouracil (5-A-RU).  13. 2018
• The nonlinear relationship between cerebrospinal fluid Aβ42 and tau in preclinical Alzheimer’s disease.  13:e0191240. 2018
• Electrocardiographic left atrial abnormality and silent vascular brain injury: The Northern Manhattan Study.  13:e0203774. 2018
• Is obstructive sleep apnea associated with difficult airway? Evidence from a systematic review and meta-analysis of prospective and retrospective cohort studies.  13:e0204904. 2018
• Lower serum IgA is associated with COPD exacerbation risk in SPIROMICS.  13:e0194924. 2018
• Predictors of death including quality of positive pressure ventilation during newborn resuscitation and the relationship to outcome at seven days in a rural Tanzanian hospital.  13:e0202641. 2018
• Preliminary study of tumor heterogeneity in imaging predicts two year survival in pancreatic cancer patients.  12:e0188022. 2017
• Association between diabetes mellitus and active tuberculosis: A systematic review and meta-analysis.  12:e0187967. 2017
• Membrane order in the plasma membrane and endocytic recycling compartment.  12:e0188041. 2017
• Treatment with solubilized Silk-Derived Protein (SDP) enhances rabbit corneal epithelial wound healing.  12:e0188154. 2017
• HIV protease inhibitor-induced cardiac dysfunction and fibrosis is mediated by platelet-derived TGF-β1 and can be suppressed by exogenous carbon monoxide.  12:e0187185. 2017
• Perimenopause and emergence of an Alzheimer’s bioenergetic phenotype in brain and periphery.  12:e0185926. 2017
• Total disc replacement using tissue-engineered intervertebral discs in the canine cervical spine.  12:e0185716. 2017
• XX Disorder of Sex Development is associated with an insertion on chromosome 9 and downregulation of RSPO1 in dogs (Canis lupus familiaris).  12:e0186331. 2017
• Multiplanar strain quantification for assessment of right ventricular dysfunction and non-ischemic fibrosis among patients with ischemic mitral regurgitation.  12:e0185657. 2017
• SIRT1 is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis.  12:e0185236. 2017
• The effect of HIV infection and HCV viremia on inflammatory mediators and hepatic injury—The Women’s Interagency HIV Study.  12:e0181004. 2017
• Time to publication of oncology trials and why some trials are never published.  12:e0184025. 2017
• Variability in objective and subjective measures affects baseline values in studies of patients with COPD.  12:e0184606. 2017
• Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.  12:e0180541. 2017
• Carbon nanotubes exhibit fibrillar pharmacology in primates.  12:e0183902. 2017
• Corneal confocal microscopy is a rapid reproducible ophthalmic technique for quantifying corneal nerve abnormalities.  12:e0183040. 2017
• D-cycloserine improves synaptic transmission in an animal mode of Rett syndrome.  12:e0183026. 2017
• Expression of PD-L1 and other immunotherapeutic targets in thymic epithelial tumors.  12:e0182665. 2017
• The prevalence and incidence of active syphilis in women in Morocco, 1995-2016: Model-based estimation and implications for STI surveillance.  12:e0181498. 2017
• Delineation of the role of chromatin assembly and the Rtt101^Mms1 E3 ubiquitin ligase in DNA damage checkpoint recovery in budding yeast.  12:e0180556. 2017
• Diagnostic utility of corneal confocal microscopy and intra-epidermal nerve fibre density in diabetic neuropathy.  12:e0180175. 2017
• Effects of exogenous glucagon-like peptide-2 and distal bowel resection on intestinal and systemic adaptive responses in rats.  12:e0181453. 2017
• Effects of oxidative and thermal stresses on stress granule formation in human induced pluripotent stem cells.  12:e0182059. 2017
• Enriched environment and stress exposure influence splenic B lymphocyte composition.  12:e0180771. 2017
• Tumor Necrosis Factor dynamically regulates the mRNA stabilome in rheumatoid arthritis fibroblast-like synoviocytes.  12:e0179762. 2017
• A phase i study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors.  12:e0178593. 2017
• Migrants, healthy worker effect, and mortality trends in the Gulf Cooperation Council countries.  12:e0179711. 2017
• Successful implementation of helping babies survive and helping mothers survive programs-An utstein formula for newborn and maternal survival.  12:e0178073. 2017
• The association between various smoking behaviors, cotinine biomarkers and skin autofluorescence, a marker for advanced glycation end product accumulation.  12:e0179330. 2017
• Total control of fat cells from adipogenesis to apoptosis using a xanthene analog.  12:e0179158. 2017
• Treatment with macrolides and glucocorticosteroids in severe communityacquired pneumonia: A post-hoc exploratory analysis of a randomized controlled trial.  12:e0178022. 2017
• Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation.  12:e0176562. 2017
• Inflammatory biomarkers as predictors of heart failure in women without obstructive coronary artery disease: A report from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE).  12:e0177684. 2017
• Risk factors for hepatitis C seropositivity among young people who inject drugs in New York City: Implications for prevention.  12:e0177341. 2017
• SIRT1 is a positive regulator of the master osteoblast transcription factor, RUNX2.  12:e0178520. 2017
• Antimicrobial-resistant infections among postpartum women at a Ugandan referral hospital.  12:e0175456. 2017
• MAIT cells are reduced in frequency and functionally impaired in human T lymphotropic virus type 1 infection: Potential clinical implications.  12:e0175345. 2017
• Outcomes after antiretroviral therapy during the expansion of HIV services in Haiti.  12:e0175521. 2017
• Sliding scale HCG trigger yields equivalent pregnancy outcomes and reduces ovarian hyperstimulation syndrome: Analysis of 10,427 IVF-ICSI cycles.  12:e0176019. 2017
• Distance in cancer gene expression from stem cells predicts patient survival.  12:e0173589. 2017
• Right atrial volume by cardiovascular magnetic resonance predicts mortality in patients with heart failure with reduced ejection fraction.  12:e0173245. 2017
• Waterpipe smoking induces epigenetic changes in the small airway epithelium.  12:e0171112. 2017
• A cyclin-dependent kinase inhibitor, dinaciclib in preclinical treatment models of thyroid cancer.  12:e0172315. 2017
• Chemotherapy induces adaptive drug resistance and metastatic potentials via phenotypic CXCR4-expressing cell state transition in ovarian cancer.  12:e0171044. 2017
• Patient experience with outpatient encounters at public hospitals in Shanghai: Examining different aspects of physician services and implications of overcrowding.  12:e0171684. 2017
• A low peripheral blood CD4/CD8 ratio is associated with pulmonary emphysema in HIV.  12:e0170857. 2017
• Assessment of corneal sensation, innervation and retinal nerve fiber layer in patients treated with multiple intravitreal ranibizumab injections.  12:e0170271. 2017
• Could circumcision of HIV-positive males benefit voluntary medical male circumcision programs in Africa? Mathematical modeling analysis.  12:e0170641. 2017
• HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers.  12:e0181886. 2017
• Human Papillomavirus (HPV) infection: Molecular epidemiology, genotyping, seroprevalence and associated risk factors among Arab women in Qatar.  12:e0169197. 2017
• Imaging radiation-induced gastrointestinal, bone marrow injury and recovery kinetics using ¹⁸F-FDG PET.  12:e0169082. 2017
• Mesenchymal cell reprogramming in experimental MPL^W515L mouse model of myelofibrosis.  12:e0166014. 2017
• Rare synaptogenesis-impairing mutations in SLITRK5 are associated with obsessive compulsive disorder.  12:e0169994. 2017
• Relationship between clinical parameters and brain structure in sporadic amyotrophic lateral sclerosis patients according to onset type: A voxel-based morphometric study.  12:e0168424. 2017
• Review and analysis of publication trends over three decades in three high impact medicine journals.  12:e0170056. 2017
• The Systematic Evaluation of Identifying the Infarct Related Artery Utilizing Cardiac Magnetic Resonance in Patients Presenting with ST-Elevation Myocardial Infarction.  12:e0169108. 2017
• The burden of mental disorders in the eastern mediterranean region, 1990-2013.  12:e0169575. 2017
• The phage lysin PlySs2 Decolonizes Streptococcus suis from murine intranasal mucosa.  12:e0169180. 2017
• The prevalence and metabolic characteristics of polycystic ovary syndrome in the Qatari population.  12:e0181467. 2017
• Direct unequal cleavages: Embryo developmental competence, genetic constitution and clinical outcome.  11:e0166398. 2016
• Lymph node transplantation decreases swelling and restores immune responses in a transgenic model of lymphedema.  11:e0168259. 2016
• Structural mapping and functional characterization of zebrafish class B G-protein coupled receptor (GPCR) with dual ligand selectivity towards GLP-1 and glucagon.  11:e0167718. 2016
• CDH1 missense variant c.1679C>G (p. T560R) completely disrupts normal splicing through creation of a novel 5′ splice site.  11:e0165654. 2016
• How do qataris source health information?.  11:e0166250. 2016
• Identifying maternal constraints on fetal growth and subsequent perinatal outcomes using a multiple embryo implantation model.  11:e0166222. 2016
• P16^INK4aexpression and immunologic aging in chronic HIV infection.  11:e0166759. 2016
• Anti-epidermal growth factor receptor gene therapy for glioblastoma.  11. 2016
• Integrated left ventricular global transcriptome and proteome profiling in human end-stage dilated cardiomyopathy.  11:e0162669. 2016
• Resolution of pulsatile tinnitus after venous sinus stenting in patients with Idiopathic Intracranial Hypertension.  11:e0164466. 2016
• The transcriptional signature of active tuberculosis reflects symptom status in extra-pulmonary and pulmonary tuberculosis.  11:e0162220. 2016
• Circulating plasma levels of MicroRNA-21 and MicroRNA-221 are potential diagnostic markers for primary intrahepatic cholangiocarcinoma.  11:e0163699. 2016
• Detection of IgG Anti-leishmania antigen by flow cytometry as a diagnostic test for cutaneous leishmaniasis.  11. 2016
• Microbial characterization of Qatari Barchans and Dunes.  11:e0161836. 2016
• Novel metabolic abnormalities in the tricarboxylic acid cycle in peripheral cells from huntington's disease patients.  11. 2016
• Obligatory role of EP1 receptors in the increase in cerebral blood flow produced by hypercapnia in the mice.  11:e0163329. 2016
• Quantitation of murine stroma and selective purification of the human tumor component of patient-derived xenografts for genomic analysis.  11. 2016
• Tumor-infiltrating macrophages in post-transplant, relapsed classical Hodgkin lymphoma are donor-derived.  11:e0163559. 2016
• Validation of the Arabic version of calgary depression scale for schizophrenia.  11. 2016
• ATmprss2-CreER^T2 knock-in mouse model for cancer genetic studies on prostate and colon.  11:e0161084. 2016
• HIV-1-specific antibody response and function after DNA prime and recombinant adenovirus 5 boost HIV vaccine in HIV-infected subjects.  11:e0160341. 2016
• SWEF proteins distinctly control maintenance and differentiation of hematopoietic stem cells.  11:e0161060. 2016
• Six-SOMAmer index relating to immune, protease and angiogenic functions predicts progression in IPF.  11:e0159878. 2016
• Spontaneous changes in taste sensitivity of single units recorded over consecutive days in the brainstem of the awake rat.  11:e0160143. 2016
• Multiparametric classification of skin from osteogenesis imperfecta patients and controls by quantitative magnetic resonance microimaging.  11:e0157891. 2016
• PARP inhibitors in clinical use induce genomic instability in normal human cells.  11:e0159341. 2016
• Pitavastatin differentially modulates MicroRNA-Associated cholesterol transport proteins in macrophages.  11:e0159130. 2016
• Sepsis caused by extended-spectrum beta-lactamase (ESBL)-positive K. pneumoniae and E. coli: Comparison of severity of sepsis, delay of anti-infective therapy and ESBL genotype.  11:e0158039. 2016
• Significance of epicardial and intrathoracic adipose tissue volume among type 1 diabetes patients in the DCCT/EDIC: A pilot study.  11:e0159958. 2016
• Type 2 diabetes risk allele loci in the Qatari population.  11:e0156834. 2016
• Association between placental lesions, cytokines and angiogenic factors in pregnant women with preeclampsia.  11:e0157584. 2016
• Malaria parasite clag3, a protein linked to nutrient channels, participates in high molecular weight membrane-associated complexes in the infected erythrocyte.  11:e0157390. 2016
• Protective effect of dual-strain probiotics in preterm infants: A multi-center time series analysis.  11:e0158136. 2016
• Simultaneous bilateral ophthalmic artery chemosurgery for bilateral retinoblastoma (tandem therapy).  11:e0156806. 2016
• Specific metabolic markers are associated with future waist-gaining phenotype in women.  11:e0157733. 2016
• Abdominal obesity, race and chronic kidney disease in young adults: Results from NHANES 1999-2010.  11:e0153588. 2016
• Impact of the sensory neurons on melanoma growth in vivo.  11:e0156095. 2016
• Neonatal mortality of planned home birth in the United States in relation to professional certification of birth attendants.  11:e0155721. 2016
• Overcoming resistance of cancer cells to PARP-1 inhibitors with three different drug combinations.  11:e0155711. 2016
• The commercial antibodies widely used to measure H3 K56 acetylation are non-specific in human and drosophila cells.  11:e0155409. 2016
• A single amino acid substitution prevents recognition of a dominant human aquaporin-4 determinant in the context of HLA-DRB1-03:01 by a murine TCR.  11:e0152720. 2016
• Body site is a more determinant factor than human population diversity in the healthy skin microbiome.  11:e0151990. 2016
• Genetic influences on metabolite levels: A comparison across metabolomic platforms.  11:e0153672. 2016
• Ghrelin inhibits post-operative adhesions via blockage of the TGF-β signaling pathway.  11:e0153968. 2016
• Molecular Self-Assembly strategy for generating catalytic hybrid polypeptides.  11:e0153700. 2016
• The pharmacogenetic footprint of ACE inhibition: A population-based metabolomics study.  11:e0153163. 2016
• CHOP chemotherapy for aggressive non-Hodgkin lymphoma with and without HIV in the antiretroviral therapy era in Malawi.  11:e0150445. 2016
• Comparative effectiveness of etanercept and adalimumab in patient reported outcomes and injection-related tolerability.  11:e0149781. 2016
• Diagnosis of HIV-Associated oral lesions in relation to early versus delayed antiretroviral therapy: Results from the CIPRA HT001 Trial.  11:e0150656. 2016
• Parameterization for in-silico modeling of ion channel interactions with drugs.  11:e0150761. 2016
• Polarity-dependent misperception of subjective visual vertical during and after transcranial direct current stimulation (tDCS).  11:e0152331. 2016
• Shedding light on the nature of seminal round cells.  11:e0151640. 2016
• The role of biliary carcinoembryonic antigen-related cellular adhesion molecule 6 (CEACAM6) a sa biomarker in cholangiocarcinoma.  11:e0150195. 2016
• Topotecan delivery to the optic nerve after ophthalmic artery chemosurgery.  11:e0151343. 2016
• α1-Syntrophin variant identified in drug-induced long QT syndrome increases late sodium current.  11:e0152355. 2016
• Analysis of transcriptional signatures in response to listeria monocytogenes infection reveals temporal changes that result from type i interferon signaling.  11:e0150251. 2016
• Association of Forced Vital Capacity with the Developmental Gene NCOR2.  11:e0147388. 2016
• Do case rates affect physicians' clinical practice in radiation oncology?: An observational study.  11:e0149449. 2016
• Modeling the cost effectiveness of neuroimaging-based treatment of acute wake-up stroke.  11:e0148106. 2016
• Morphological and hemodynamic discriminators for rupture status in posterior communicating artery aneurysms.  11:e0149906. 2016
• Trends in CD4 count testing, retention in Pre-ART care, and ART initiation rates over the first decade of expansion of HIV services in Haiti.  11:e0146903. 2016
• Intra-arterial chemotherapy (ophthalmic artery chemosurgery) for group D retinoblastoma.  11:e0146582. 2016
• Targeted curing of all lysogenic bacteriophage from streptococcus pyogenes using a novel counter-selection technique.  11:e0146408. 2016
• A germline variant on chromosome 4q31.1 associates with susceptibility to developing colon cancer metastasis.  11:e0146435. 2016
• Serum biomarkers associated with clinical outcomes fail to predict brain metastases in patients with stage IV non-small cell lung cancers.  11:e0146063. 2016
• The influence of tissue ischemia time on RNA integrity and patient-derived xenografts (PDX) engraftment rate in a non-small cell lung cancer (NSCLC) Biobank.  11:e0145100. 2016
• Alterations in Lipid and Inositol Metabolisms in Two Dopaminergic Disorders.  11:e0147129. 2016
• Anticipatory posturing of the vocal tract reveals dissociation of speech movement plans from linguistic units.  11:e0146813. 2016
• Are early relapses in advanced-stage ovarian cancer doomed to a poor prognosis?.  11:e0147787. 2016
• Association of right ventricular pressure and volume overload with non-ischemic septal fibrosis on cardiac magnetic resonance.  11:e0147349. 2016
• Frequent Users of Hospital Emergency Departments in Korea Characterized by Claims Data from the National Health Insurance: A Cross Sectional Study.  11:e0147450. 2016
• KS-detect validation of solar thermal PCR for the diagnosis of kaposi's sarcoma using pseudo-biopsy samples.  11:e0147636. 2016
• Optical imaging of PARP1 in response to radiation in oral squamous cell carcinoma.  11:e0147752. 2016
• SsDNA aptamer specifically targets and selectively delivers cytotoxic drug doxorubicin to HepG2 Cells.  11:e0147674. 2016
• Advanced unilateral retinoblastoma: The impact of ophthalmic artery chemosurgery on Enucleation rate and patient survival at MSKCC.  10:e0145436. 2015
• Comprehensible predictive modeling using regularized logistic regression and comorbidity based features.  10:e0144439. 2015
• Development and validation of a gene-based model for outcome prediction in germ cell tumors using a combined genomic and expression profiling approach.  10:e0142846. 2015
• Elimination of chromosomal Island SpyCIM1 from Streptococcus pyogenes strain SF370 reverses the mutator phenotype and alters global transcription.  10:e0145884. 2015
• Investigating voluntary medical male circumcision program efficiency gains through subpopulation prioritization: Insights from application to Zambia.  10:e0145729. 2015
• Risk of ischemic stroke after intracranial hemorrhage in patients with atrial fibrillation.  10:e0145579. 2015
• Serum metabolite biomarkers discriminate healthy smokers from COPD smokers.  10:e0143937. 2015
• Chronic diseases in North-West Tanzania and Southern Uganda. Public perceptions of terminologies, aetiologies, symptoms and preferred management.  10:e0142194. 2015
• Whole exome sequencing of rapid autopsy tumors and xenograft models reveals possible driver mutations underlying tumor progression.  10:e0142631. 2015
• Bilayer effects of antimalarial compounds.  10:e0142401. 2015
• IRF4-dependent and IRF4-independent pathways contribute to DC dysfunction in lupus.  10:e0141927. 2015
• A reevaluation of the voluntary medical male circumcision scale-up plan in Zimbabwe.  10:e0140818. 2015
• Quality control measures over 30 years in a multicenter clinical study: Results from the Diabetes Control and Complications Trial / Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study.  10:e0141286. 2015
• A Versatile Strategy for Production of Membrane Proteins with Diverse Topologies: Application to Investigation of Bacterial Homologues of Human Divalent Metal Ion and Nucleoside Transporters.  10:e0143010. 2015
• A second look at the association between gender and mortality on antiretroviral therapy.  10:e0142101. 2015
• Use of tethered enzymes as a platform technology for rapid analyte detection.  10:e0142326. 2015
• Corneal sensitivity and dry eye symptoms in patients with keratoconus.  10:e0141621. 2015
• Distinct transcript isoforms of the atypical chemokine receptor 1 (ACKR1) / Duffy Antigen Receptor for Chemokines (DARC) gene are expressed in lymphoblasts and altered isoform levels are associated with genetic ancestry and the duffy-null allele.  10:e0140098. 2015
• Estimating sampling selection bias in human genetics: A phenomenological approach.  10:e0140146. 2015
• Corneal confocal microscopy detects small fibre neuropathy in patients with upper gastrointestinal cancer and nerve regeneration in chemotherapy induced peripheral neuropathy.  10:e0139394. 2015
• Tissue-specific enrichment of lymphoma risk loci in regulatory elements.  10:e0139360. 2015
• The role of flexible loops in folding, trafficking and activity of equilibrative nucleoside transporters.  10:e0136779. 2015
• Evaluation of in vitro activity of the class i PI3K inhibitor buparlisib (BKM120) in pediatric bone and soft tissue sarcomas.  10:e0133610. 2015
• TMPyP4, a stabilizer of nucleic acid secondary structure, is a novel acetylcholinesterase inhibitor.  10:e0139167. 2015
• Combined effects of flow diverting strategies and parent artery curvature on aneurysmal hemodynamics: A CFD study.  10:e0138648. 2015
• Severe nephrotoxic nephritis following conditional and kidney-specific knockdown of stanniocalcin-1.  10:e0138440. 2015
• A Multiplex PCR/LDR Assay for the simultaneous identification of category a infectious pathogens: Agents of viral hemorrhagic fever and Variola virus.  10:e0138484. 2015
• Heterogeneous disease trajectories explain variable radiographic, function and quality of life outcomes in the Canadian Early Arthritis Cohort (CATCH).  10:e0135327. 2015
• The effect of tear supplementation on ocular surface sensations during the interblink interval in patients with dry eye.  10:e0135629. 2015
• Glucose metabolism disorders, HIV and antiretroviral therapy among tanzanian adults.  10:e0134410. 2015
• Phase II trial of sorafenib in patients with chemotherapy refractory metastatic esophageal and gastroesophageal (GE) junction cancer.  10:e0134731. 2015
• Measurement of lipid accumulation in Chlorella vulgaris via flow cytometry and liquid-state ¹H NMR spectroscopy for development of an NMR-traceable flow cytometry protocol.  10:e0134846. 2015
• Prothrombin time and activated Partial Thromboplastin Time testing: A comparative effectiveness study in a million-patient sample.  10:e0133317. 2015
• Knowledge, attitudes, practices and beliefs about Medical Male Circumcision (MMC) among a sample of health care providers in Haiti.  10:e0134667. 2015
• Cholangiocarcinoma: Correlation between molecular profiling and imaging phenotypes.  10:e0132953. 2015
• Predictors of clinical success in the treatment of patients with methicillin- resistant staphylococcus aureus (MRSA) Nosocomial pneumonia (NP).  10:e0131932. 2015
• Reduced right ventricular function predicts long-term cardiac re-hospitalization after cardiac surgery.  10:e0132808. 2015
• The validity of claims-based algorithms to identify serious hypersensitivity reactions and osteonecrosis of the jaw.  10:e0131601. 2015
• Targeting homologous recombination in Notch-driven C. elegans stem cell and human tumors.  10:e0127862. 2015
• Social network analysis for program implementation.  10:e0131712. 2015
• Tumor-targeted human T cells expressing CD28-based chimeric antigen receptors circumvent CTLA-4 inhibition.  10:e0130518. 2015
• Common genetic variation in cellular transport genes and epithelial ovarian cancer (EOC) risk.  10:e0128106. 2015
• Defining the value of future research to identify the preferred treatment of meniscal tear in the presence of knee osteoarthritis.  10:e0130256. 2015
• Improved intraoperative visualization of nerves through a myelin-binding fluorophore and dual-mode laparoscopic imaging.  10:e0130276. 2015
• Seneca valley virus 3C^pro substrate optimization yields efficient substrates for use in peptide-prodrug therapy.  10:e0129103. 2015
• Multiplexing of ChIP-seq samples in an optimized experimental condition has minimal impact on peak detection.  10:e0129350. 2015
• Proton pump inhibitor usage and the risk of myocardial infarction in the general population.  10:e0124653. 2015
• Expression of HIF-1α and markers of angiogenesis are not significantly different in triple negative breast cancer compared to other breast cancer molecular subtypes: Implications for future therapy.  10:e0129356. 2015
• Identification of reprogrammed myeloid cell transcriptomes in NSCLC.  10:e0129123. 2015
• Th2 cytokines inhibit lymphangiogenesis.  10:e0126908. 2015
• Consider the source: Adolescents and adults similarly follow older adult advice more than peer advice.  10:e0128047. 2015
• Colonization history, host distribution, anthropogenic influence and landscape features shape populations of white pine blister rust, an invasive alien tree pathogen.  10. 2015
• The group 3 innate lymphoid cell defect in aryl hydrocarbon receptor deficient mice is associated with T cell hyperactivation during intestinal infection.  10:e0128335. 2015
• Identification of DRG-1 as a melanoma-associated antigen recognized by CD4⁺ Th1 cells.  10:e0124094. 2015
• Identification of Rv3852 as an agrimophol-binding protein in mycobacterium tuberculosis.  10:e0126211. 2015
• Expression of the carboxy-terminal portion of MUC16/CA125 induces transformation and tumor invasion.  10:e0126633. 2015
• Mitochondrial Mutations in Subjects with Psychiatric Disorders.  10:e0127280. 2015
• Newly exerted T cell pressures on mutated epitopes following transmission help maintain consensus HIV-1 sequences.  10:e0120787. 2015
• Protein expression profiles characterize distinct features of mouse cerebral cortices at different developmental stages.  10:e0125608. 2015
• Characterization of bacterial and fungal microbiome in children with Hirschsprung disease with and without a history of enterocolitis:A multicenter study.  10:e0124172. 2015
• Interrogating a multifactorial model of breast conserving therapy with clinical data.  10:e0125006. 2015
• Side-by-side comparison of commonly used biomolecules that differ in size and affinity on tumor uptake and internalization.  10:e0124440. 2015
• A novel small-molecule inhibitor targeting CREB-CBP complex possesses anti-cancer effects along with cell cycle regulation, autophagy suppression and endoplasmic reticulum stress.  10:e0122628. 2015
• Cell signaling-based classifier predicts response to induction therapy in elderly patients with acute myeloid leukemia.  10:e0118485. 2015
• Persistence of smoking-induced dysregulation of MiRNA expression in the small airway epithelium despite smoking cessation.  10:e0120824. 2015
• The p53^R172H mutant does not enhance hepatocellular carcinoma development and progression.  10:e0123816. 2015
• Reversible linkage of two distinct small molecule inhibitors of myc generates a dimeric inhibitor with improved potency that is active in myc over-expressing cancer cell lines.  10:e0121793. 2015
• Systems biology analysis merging phenotype, metabolomic and genomic data identifies Non-SMC Condensin I Complex, Subunit G (NCAPG) and cellular maintenance processes as major contributors to genetic variability in Bovine feed efficiency.  10:e0124574. 2015
• Characterization of tetratricopeptide repeat-containing proteins critical for cilia formation and function.  10:e0124378. 2015
• Corneal confocal microscopy detects neuropathy in patients with type 1 diabetes without retinopathy or microalbuminuria.  10:e0123517. 2015
• Analyses of the transcriptome and metabolome demonstrate that HIF1α mediates altered tumor metabolism in clear cell renal cell carcinoma.  10:e0120649. 2015
• Assessing associations between the AURKAHMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers.  10:e0120020. 2015
• Folate receptor-a (FOLR1) expression and function in triple negative tumors.  10. 2015
• Folate receptor-α (FOLR1) expression and function in triple negative tumors.  10. 2015
• Gut microbiota and tacrolimus dosing in kidney transplantation.  10:e0122399. 2015
• Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression.  10:e0120295. 2015
• Small RNA sequencing for profiling MicroRNAs in long-term preserved formalin-fixed and paraffin-embedded non-small cell lung cancer tumor specimens.  10:e0121521. 2015
• Gp120/CD4 blocking antibodies are frequently elicited in ART-naïve chronically HIV-1 infected individuals.  10:e0120648. 2015
• Placental expression of miR-517a/b and miR-517c contributes to trophoblast dysfunction and preeclampsia.  10:e0122707. 2015
• Colorectal mucus binds DC-SIGN and inhibits HIV-1 trans-infection of CD4+ T-lymphocytes.  10:e0122020. 2015
• Inherited variation at MC1R and histological characteristics of primary melanoma.  10:e0119920. 2015
• Aspartame sensitivity? A double blind randomised crossover study.  10:e0116212. 2015
• Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor- beta1 in pulmonary fibrosis.  10:e0121246. 2015
• Hedgehog Signaling Pathway Is Active in GBM with GLI1 mRNA Expression Showing a Single Continuous Distribution Rather than Discrete High/Low Clusters.  10:e0116390. 2015
• Recall of briefly presented chess positions and its relation to chess skill.  10:e0118756. 2015
• Influence of intraaortic balloon pump counterpulsation on transesophageal echocardiography derived determinants of diastolic function.  10:e0118788. 2015
• Is metabolic syndrome predictive of prevalence, extent, and risk of coronary artery disease beyond its components? results from the multinational coronary ct angiography evaluation for clinical outcome: An international multicenter registry (confirm).  10:e0118998. 2015
• Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway.  10. 2015
• Expression of Ror2 mediates invasive phenotypes in renal cell carcinoma.  9:e116101. 2014
• Patterns in place of cancer death in the state of qatar: A population-based study.  9:e109615. 2014
• A simplified score to quantify comorbidity in COPD.  9:e114438. 2014
• An integrative computational approach for prioritization of genomic variants.  9:e114903. 2014
• Mesothelin expression in triple negative breast carcinomas correlates significantly with basal-like phenotype, distant metastases and decreased survival.  9:e114900. 2014
• Combined Ablation and Resection (CARe) as an effective parenchymal sparing treatment for extensive colorectal liver metastases.  9:e114404. 2014
• The Charlson comorbidity index can be used prospectively to identify patients who will incur high future costs.  9:e112479. 2014
• The role of lipotoxicity in smoke cardiomyopathy.  9:e113739. 2014
• Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network.  9:e111301. 2014
• Intracytoplasmic Sperm Injection (ICSI) in extreme cases of male infertility.  9:e113671. 2014
• Mechanistic insight into the Th1-biased immune response to recombinant subunit vaccines delivered by probiotic bacteria-derived outer membrane vesicles.  9:e112802. 2014
• Sleeping beauty mouse models identify candidate genes involved in gliomagenesis.  9:e113489. 2014
• Endothelial cells provide a notch-dependent pro-tumoral niche for enhancing breast cancer survival, stemness and pro-metastatic properties.  9:e112424. 2014
• Identification of molecular pathways facilitating Glioma cell invasion in situ.  9:e111783. 2014
• Evaluation of toll-like receptor 2 and 4 RNA expression and the cytokine profile in postmenopausal women with metabolic syndrome.  9:e109259. 2014
• Human equilibrative nucleoside transporter-1 knockdown tunes cellular mechanics through epithelial-mesenchymal transition in pancreatic cancer cells.  9:e107973. 2014
• MRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon cancer patients in randomized CALGB 89803 trial.  9:e108483. 2014
• Risk factors for severe neutropenia following intra-arterial chemotherapy for intra-ocular retinoblastoma.  9:e108692. 2014
• Evaluation of intereye corneal asymmetry in patients with keratoconus. A Scheimpflug imaging study.  9:e108882. 2014
• A multicenter phase l/ll study of obatoclax mesylate administered as a 3- Or 24-hour infusion in older patients with previously untreated acute myeloid leukemia.  9:e108694. 2014
• Talpid3-binding centrosomal protein Cep120 is required for centriole duplication and proliferation of cerebellar granule neuron progenitors.  9:e107943. 2014
• Accurate identification of ALK positive lung carcinoma patients: Novel FDA-cleared automated fluorescence in situ hybridization scanning system and ultrasensitive immunohistochemistry.  9:e107200. 2014
• Conserved microsatellites in ants enable population genetic and colony pedigree studies across a wide range of species.  9:e107334. 2014
• Health effects of lesion localization in multiple sclerosis: Spatial registration and confounding adjustment.  9. 2014
• Knock out of S1P3 receptor signaling attenuates inflammation and fibrosis in bleomycin-induced lung Injury Mice Model.  9:e106792. 2014
• A recommendation for revised dose calibrator measurement procedures for 89Zr and 124I.  9:e106868. 2014
• Genitourinary defects associated with genomic deletions in 2p15 encompassing OTX1.  9:e107028. 2014
• How accurate is MOLLI T1 mapping in vivo? Validation by spin echo methods.  9:e107327. 2014
• Interleukin-4 regulates eomesodermin in CD8⁺ T cell development and differentiation.  9:e106659. 2014
• Population structure of mountain pine beetle symbiont Leptographium longiclavatum and the implication on the multipartite beetle-fungi relationships.  9. 2014
• Remodeling of the methylation landscape in breast cancer metastasis.  9:e103896. 2014
• Gene expression analysis of children with acute hematogenous osteomyelitis caused by methicillin-resistant staphylococcus aureus: Correlation with clinical severity of illness.  9:e103523. 2014
• SIRT2 deficiency modulates macrophage polarization and susceptibility to experimental colitis.  9:e103573. 2014
• Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism.  9:e102978. 2014
• Both canonical and non-canonical Wnt signaling independently promote stem cell growth in mammospheres.  9:e101800. 2014
• Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer.  9:e102495. 2014
• Genetic variation in DNA repair pathways and risk of non-Hodgkin's lymphoma.  9:e101685. 2014
• Cost-effectiveness of the "Helping Babies Breathe" program in a Missionary Hospital in rural Tanzania.  9:e102080. 2014
• The roles of individual mammalian argonautes in RNA interference in vivo.  9:e101749. 2014
• Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas.  9:e101010. 2014
• cAMP control of HCN2 channel Mg2+ block reveals loose coupling between the cyclic nucleotide-gating ring and the pore.  9:e101236. 2014
• Sugar-sweetened beverage intake and cancer recurrence and survival in CALGB 89803 (Alliance).  9:e99816. 2014
• Rat middle cerebral artery occlusion is not a suitable model for the study of stroke-induced spontaneous infections.  9:e99169. 2014
• Ubiquitin Specific Protease 26 (USP26) expression analysis in human testicular and extragonadal tissues indicates diverse action of USP26 in cell differentiation and tumorigenesis.  9:e98638. 2014
• Development of a novel multiplex PCR assay to detect functional subtypes of KIR3DL1 alleles.  9:e99543. 2014
• P wave area for quantitative electrocardiographic assessment of left atrial remodeling.  9:e99178. 2014
• Multi-compartment T2 relaxometry using a spatially constrained multi-Gaussian model.  9:e98391. 2014
• Wnt signaling activates Shh signaling in early postnatal intervertebral discs, and re-activates Shh signaling in old discs in the mouse.  9:e98444. 2014
• Continuous quality improvement in daily clinical practice: A proof of concept study.  9:e97066. 2014
• Identification of the key differential transcriptional responses of human whole blood following TLR2 or TLR4 ligation in-vitro.  9:e97702. 2014
• Safety, pharmacokinetic, and functional effects of the Nogo-A monoclonal antibody in amyotrophic lateral sclerosis: A randomized, first-in-human clinical trial.  9:e97803. 2014
• The hepatitis C cascade of care: Identifying priorities to improve clinical outcomes.  9:e97317. 2014
• Mucosal immunization with integrase-defective lentiviral vectors protects against influenza virus challenge in mice.  9:e97270. 2014
• Simplification to abacavir/lamivudine + atazanavir maintains viral suppression and improves bone and renal biomarkers in ASSURE, a randomized, open label, non-inferiority trial.  9:e96187. 2014
• Intermediate-type vancomycin resistance (VISA) in genetically-distinct staphylococcus aureus isolates is linked to specific, reversible metabolic alterations.  9:e97137. 2014
• Exome-wide association study of endometrial cancer in a multiethnic population.  9:e97045. 2014
• Baseline natural killer and T cell populations correlation with virologic outcome after regimen simplification to atazanavir/ritonavir alone (ACTG 5201).  9:e95524. 2014
• Continuing a cancer treatment despite tumor growth may be valuable: Sunitinib in renal cell carcinoma as example.  9:e96316. 2014
• Loss of function of TET2 cooperates with constitutively active KIT in murine and human models of mastocytosis.  9:e96209. 2014
• Brain without anatomy: Construction and comparison of fully network-driven structural MRI connectomes.  9:e96196. 2014
• A comparison of supervised machine learning algorithms and feature vectors for MS lesion segmentation using multimodal structural MRI.  9. 2014
• Inhibition of breast cancer metastasis suppressor 1 promotes a mesenchymal phenotype in lung epithelial cells that express oncogenic k-rasv12and loss of p53.  9:e95869. 2014
• Conditional reverse tet-transactivator mouse strains for the efficient induction of tre-regulated transgenes in mice.  9:e95236. 2014
• Mapping the genetic architecture of gene regulation in whole blood.  9:e93844. 2014
• Activation of GPER-1 estradiol receptor downregulates production of testosterone in isolated rat leydig cells and adult human testis.  9:e92425. 2014
• Completely ES cell-derived mice produced by tetraploid complementation using inner cell mass (ICM) deficient blastocysts.  9:e94730. 2014
• Micro-environment causes reversible changes in DNA methylation and mRNA expression profiles in patient-derived glioma stem cells.  9:e94045. 2014
• Emphysema predicts hospitalisation and incident airflow obstruction among older smokers: A prospective cohort study.  9:e93221. 2014
• Metabolic signatures of cultured human adipocytes from metabolically healthy versus unhealthy obese individuals.  9:e93148. 2014
• Discovering aptamers by cell-SELEX against human soluble growth factors ectopically expressed on yeast cell surface.  9:e93052. 2014
• The association between adiposity, mental well-being, and quality of life in extreme obesity.  9:e92859. 2014
• Early Clostridium difficile infection during allogeneic hematopoietic stem cell transplantation.  9:e90158. 2014
• Pregnancy differentially impacts performance of latent tuberculosis diagnostics in a high-burden setting.  9:e92308. 2014
• Vaccination against endogenous retrotransposable element consensus sequences does not protect rhesus macaques from SIVsmE660 infection and replication.  9:e92012. 2014
• Endotoxin-induced monocytic microparticles have contrasting effects on endothelial inflammatory responses.  9:e91597. 2014
• Identification of novel CELSR1 mutations in spina bifida.  9:e92207. 2014
• Signaling role of prokineticin 2 on the estrous cycle of female mice.  9:e90860. 2014
• Psychological stress and 30-day all-cause hospital readmission in acute coronary syndrome patients: An observational cohort study.  9:e91477. 2014
• An active learning approach for rapid characterization of endothelial cells in human tumors.  9:e90495. 2014
• Correlation between genotypic and phenotypic testing for resistance to rifampin in Mycobacterium tuberculosis clinical isolates in Haiti: Investigation of cases with discrepant susceptibility results.  9:e90569. 2014
• Dual mode action of mangiferin in mouse liver under high fat diet.  9:e90137. 2014
• The warmer the weather, the more gram-negative bacteria - Impact of temperature on clinical isolates in intensive care units.  9:e91105. 2014
• IL-17 induces an expanded range of downstream genes in reconstituted human epidermis model.  9:e90284. 2014
• Impact of antiretroviral therapy on renal function among HIV-infected tanzanian adults: A retrospective cohort study.  9:e89573. 2014
• Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase.  9:e89938. 2014
• Self-gated free-breathing 3D coronary CINE imaging with simultaneous water and fat visualization.  9:e89315. 2014
• Cannabinoid neuromodulation in the adult early visual cortex.  9:e87362. 2014
• Self-reported history of childhood smoking is associated with an increased risk for peripheral arterial disease independent of lifetime smoking burden.  9:e88972. 2014
• Transient mild hyperthermia induces e-selectin mediated localization of mesoporous silicon vectors in solid tumors.  9:e86489. 2014
• Healthcare worker perceived barriers to early initiation of antiretroviral and tuberculosis therapy among tanzanian inpatients.  9:e87584. 2014
• Estimating risk of C. difficile transmission from PCR positive but cytotoxin negative cases.  9:e88262. 2014
• Integration of sequence data from a consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene.  9:e87645. 2014
• Drug-induced trafficking of P-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C.  9:e88154. 2014
• Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2.  9:e88051. 2014
• A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events.  9:e87361. 2014
• Trkb signaling in pericytes is required for cardiac microvessel stabilization.  9:e87406. 2014
• Metabolomic derangements are associated with mortality in critically ill adult patients.  9:e87538. 2014
• Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells.  9:e79987. 2014
• Urine microRNA as potential biomarkers of autosomal dominant polycystic kidney disease progression: Description of miRNA profiles at baseline.  9:e86856. 2014
• Regulatory T cell ablation causes acute T cell lymphopenia.  9:e86762. 2014
• Composition and function of T cell subpopulations are slow to change despite effective antiretroviral treatment of HIV disease.  9:e85613. 2014
• Electroretinogram monitoring of dose-dependent toxicity after ophthalmic artery chemosurgery in retinoblastoma eyes: Six year review.  9:e84247. 2014
• Intraflagellar transport gene expression associated with short cilia in smoking and COPD.  9:e85453. 2014
• Interleukin-21 is a critical regulator of CD4 and CD8 T cell survival during priming under interleukin-2 deprivation conditions.  9:e85882. 2014
• Pyruvate protects pathogenic spirochetes from H2O2 killing.  9. 2014
• A CACNA1C variant associated with reduced voltage-dependent inactivation, increased Ca<inf>V</inf>1.2 channel window current, and arrhythmogenesis.  9:e106982. 2014
• Enhanced immunogenicity of HIV-1 envelope gp140 proteins fused to APRIL.  9:e107683. 2014
• Circulating tumor cells from prostate cancer patients interact with E-selectin under physiologic blood flow.  8:e85143. 2013
• Myeloid cell sirtuin-1 expression does not alter host immune responses to gram-negative endotoxemia or gram-positive bacterial infection.  8:e84481. 2013
• Growth pattern analysis of murine lung neoplasms by advanced semi-automated quantification of micro-CT images.  8:e83806. 2013
• Microfluidic generated EGF-gradients induce chemokinesis of transplantable retinal progenitor cells via the JAK/STAT and PI3kinase signaling pathways.  8:e83906. 2013
• Barriers to malaria control among marginalized tribal communities: A qualitative study.  8:e81966. 2013
• Molecular mechanisms mediating a deficit in recall of fear extinction in adult mice exposed to cocaine in utero.  8:e84165. 2013
• The impact of a diabetes local enhanced service on quality outcome framework diabetes outcomes.  8:e83738. 2013
• The sodium/proline transporter PutP of Helicobacter pylori.  8:e83576. 2013
• Enhanced responses to tumor immunization following total body irradiation are time-dependent.  8:e82496. 2013
• CD86 is an activation receptor for nk cell cytotoxicity against tumor cells.  8:e83913. 2013
• Gene expression profiles accurately predict outcome following liver resection in patients with metastatic colorectal cancer.  8:e81680. 2013
• Lack of RNase L attenuates macrophage functions.  8:e81269. 2013
• Central role for MCP-1/CCL2 in injury-induced inflammation revealed by in vitro, in silico, and clinical studies.  8:e79804. 2013
• Colorimetric and longitudinal analysis of leukocoria in recreational photographs of children with retinoblastoma..  8:e76677. 2013
• Correlated spontaneous activity persists in adult retina and is suppressed by inhibitory inputs..  8:e77658. 2013
• IKKα/CHUK regulates extracellular matrix remodeling independent of its kinase activity to facilitate articular chondrocyte differentiation..  8:e73024. 2013
• Risk factors associated with the community-acquired colonization of extended-spectrum beta-lactamase (ESBL) positive Escherichia Coli. an exploratory case-control study..  8:e74323. 2013
• A machine learning approach to automated structural network analysis: Application to neonatal encephalopathy.  8:e78824. 2013
• Polymorphisms in alcohol metabolism genes ADH1B and ALDH2, alcohol consumption and colorectal cancer.  8:e80158. 2013
• Persistence of hepatitis C virus during and after otherwise clinically successful treatment of chronic hepatitis C with standard pegylated interferon α-2b and ribavirin therapy.  8:e80078. 2013
• Analysis of morphological parameters to differentiate rupture status in anterior communicating artery aneurysms.  8:e79635. 2013
• Quantifying cancer absolute risk and cancer mortality in the presence of competing events after a myotonic dystrophy diagnosis.  8:e79851. 2013
• DOK2 inhibits EGFR-mutated lung adenocarcinoma.  8:e79526. 2013
• Eukaryotic Initiation Factor 2α - a Downstream Effector of Mammalian Target of Rapamycin - Modulates DNA Repair and Cancer Response to Treatment.  8:e77260. 2013
• Metformin Targets the Metabolic Achilles Heel of Human Pancreatic Cancer Stem Cells.  8:e76518. 2013
• M.tuberculosis Mutants Lacking Oxygenated Mycolates Show Increased Immunogenicity and Protective Efficacy as Compared to M. bovis BCG Vaccine in an Experimental Mouse Model.  8:e76442. 2013
• Isolation of Clostridium perfringens Type B in an Individual at First Clinical Presentation of Multiple Sclerosis Provides Clues for Environmental Triggers of the Disease.  8:e76359. 2013
• Identification of Genes Potentially Regulated by Human Polynucleotide Phosphorylase (hPNPase^old-35) Using Melanoma as a Model.  8. 2013
• Utility of a Histone Deacetylase Inhibitor (PXD101) for Thyroid Cancer Treatment.  8:e77684. 2013
• Targeted Exome Sequencing Integrated with Clinicopathological Information Reveals Novel and Rare Mutations in Atypical, Suspected and Unknown Cases of Alport Syndrome or Proteinuria.  8. 2013
• CATP-6, a C. elegans Ortholog of ATP13A2 PARK9, Positively Regulates GEM-1, an SLC16A Transporter.  8:e77202. 2013
• An Animal Explant Model for the Study of Human Cutaneous Squamous Cell Carcinoma.  8:e76156. 2013
• Identification of Leptospira interrogans Phospholipase C as a Novel Virulence Factor Responsible for Intracellular Free Calcium Ion Elevation during Macrophage Death.  8:e75652. 2013
• Simulation of Platelet, Thrombus and Erythrocyte Hydrodynamic Interactions in a 3D Arteriole with In Vivo Comparison.  8:e76949. 2013
• Meaning Making in Cancer Survivors: A Focus Group Study.  8:e76089. 2013
• Small Molecule Injection into Single-Cell C. elegans Embryos via Carbon-Reinforced Nanopipettes.  8:e75712. 2013
• Deficiency in Repair of the Mitochondrial Genome Sensitizes Proliferating Myoblasts to Oxidative Damage.  8:e75201. 2013
• Duration of Anti-Tuberculosis Therapy and Timing of Antiretroviral Therapy Initiation: Association with Mortality in HIV-Related Tuberculosis.  8:e74057. 2013
• Interferon Signature in the Blood in Inflammatory Common Variable Immune Deficiency.  8:e74893. 2013
• An Absolute Risk Model to Identify Individuals at Elevated Risk for Pancreatic Cancer in the General Population.  8:e72311. 2013
• HIV-1 Envelope Glycoprotein Resistance to Monoclonal Antibody 2G12 Is Subject-Specific and Context-Dependent in Macaques and Humans.  8:e75277. 2013
• High Correlation of the Response of Upper and Lower Lobe Small Airway Epithelium to Smoking.  8:e72669. 2013
• Factors Secreted by Endothelial Progenitor Cells Enhance Neurorepair Responses after Cerebral Ischemia in Mice.  8:e73244. 2013
• Spectrum of Ocular Manifestations in CLN2-Associated Batten (Jansky-Bielschowsky) Disease Correlate with Advancing Age and Deteriorating Neurological Function.  8:e73128. 2013
• Carboplatin +/- Topotecan Ophthalmic Artery Chemosurgery for Intraocular Retinoblastoma.  8:e72441. 2013
• Tissue plasminogen activator in trabecular meshwork attenuates steroid induced outflow resistance in mice.  8:e72447. 2013
• Deep Tissue Injury in Development of Pressure Ulcers: A Decrease of Inflammasome Activation and Changes in Human Skin Morphology in Response to Aging and Mechanical Load.  8:e69223. 2013
• Obesity Impairs Lymphatic Fluid Transport and Dendritic Cell Migration to Lymph Nodes.  8:e70703. 2013
• An Investigation into the Strength of the Association and Agreement Levels between Subjective and Objective Sleep Duration in Adolescents.  8:e72406. 2013
• Adenoviral Transduction of Human Acid Sphingomyelinase into Neo-Angiogenic Endothelium Radiosensitizes Tumor Cure.  8:e69025. 2013
• Association between Bone Mineral Density and Incidence of Breast Cancer.  8:e70980. 2013
• Chemoirradiation for Glioblastoma Multiforme: The National Cancer Institute Experience.  8:e70745. 2013
• Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers.  8:e70630. 2013
• TP53 and Let-7a micro-RNA Regulate K-Ras Activity in HCT116 Colorectal Cancer Cells.  8:e70604. 2013
• Mortality Trends in Women and Men Presenting with Acute Coronary Syndrome: Insights from a 20-Year Registry.  8:e70066. 2013
• The Relative Expression of Mig6 and EGFR Is Associated with Resistance to EGFR Kinase Inhibitors.  8:e68966. 2013
• NF-κB Regulates Mesenchymal Transition for the Induction of Non-Small Cell Lung Cancer Initiating Cells.  8:e68597. 2013
• Whole Cell Screen for Inhibitors of pH Homeostasis in Mycobacterium tuberculosis.  8:e68942. 2013
• An Apparent Lack of Epidemiologic Association between Hepatitis C Virus Knowledge and the Prevalence of Hepatitis C Infection in a National Survey in Egypt.  8:e69803. 2013
• Mutations in Planar Cell Polarity Gene SCRIB Are Associated with Spina Bifida.  8:e69262. 2013
• Optimizing Nasal Potential Difference Analysis for CFTR Modulator Development: Assessment of Ivacaftor in CF Subjects with the G551D-CFTR Mutation.  8:e66955. 2013
• Targeting the Giant Cell Tumor Stromal Cell: Functional Characterization and a Novel Therapeutic Strategy.  8:e69101. 2013
• Transient Combination Therapy Targeting the Immune Synapse Abrogates T Cell Responses and Prolongs Allograft Survival in Mice.  8:e69397. 2013
• p16 Stimulates CDC42-Dependent Migration of Hepatocellular Carcinoma Cells.  8:e69389. 2013
• High-Sensitivity C-Reactive Protein and Risk of Sepsis.  8:e69232. 2013
• The Role of Cancer-Testis Antigens as Predictive and Prognostic Markers in Non-Small Cell Lung Cancer.  8:e67876. 2013
• HIV-1 Autologous Antibody Neutralization Associates with Mother to Child Transmission.  8:e69274. 2013
• Dual Regulatory Roles of Human AP-Endonuclease (APE1/Ref-1) in CDKN1A/p21 Expression.  8:e68467. 2013
• Triglyceride/HDL Ratio as a Screening Tool for Predicting Success at Reducing Anti-Diabetic Medications Following Weight Loss.  8:e69285. 2013
• Indolent Small Intestinal CD4+ T-cell Lymphoma Is a Distinct Entity with Unique Biologic and Clinical Features.  8:e68343. 2013
• Assessment of SLX4 Mutations in Hereditary Breast Cancers.  8. 2013
• Comparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein Trimers.  8:e67484. 2013
• An HIV-1 Envelope Glycoprotein Trimer with an Embedded IL-21 Domain Activates Human B Cells.  8:e67309. 2013
• Application of Multiplexed Kinase Inhibitor Beads to Study Kinome Adaptations in Drug-Resistant Leukemia.  8:e66755. 2013
• Discovery and Validation of a Prostate Cancer Genomic Classifier that Predicts Early Metastasis Following Radical Prostatectomy.  8:e66855. 2013
• Tumorspheres but Not Adherent Cells Derived from Retinoblastoma Tumors Are of Malignant Origin.  8:e63519. 2013
• Two Distinct Categories of Focal Deletions in Cancer Genomes.  8:e66264. 2013
• Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry.  8:e67306. 2013
• Markers of Celiac Disease and Gluten Sensitivity in Children with Autism.  8:e66155. 2013
• Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts.  8:e66371. 2013
• Glutamine Supplementation Alleviates Vasculopathy and Corrects Metabolic Profile in an In Vivo Model of Endothelial Cell Dysfunction.  8:e65458. 2013
• Fibulin-2 Is a Driver of Malignant Progression in Lung Adenocarcinoma.  8:e67054. 2013
• A Role for Uric Acid and the Nalp3 Inflammasome in Antiphospholipid Antibody-Induced IL-1β Production by Human First Trimester Trophoblast.  8:e65237. 2013
• Caregiver Evaluation of the Quality of End-Of-Life Care (CEQUEL) Scale: The Caregiver's Perception of Patient Care Near Death.  8:e66066. 2013
• α-Lipoic Acid Antioxidant Treatment Limits Glaucoma-Related Retinal Ganglion Cell Death and Dysfunction.  8:e65389. 2013
• A Multi-System Approach Assessing the Interaction of Anticonvulsants with P-gp.  8:e64854. 2013
• Fatty Acid Synthase Is a Key Target in Multiple Essential Tumor Functions of Prostate Cancer: Uptake of Radiolabeled Acetate as a Predictor of the Targeted Therapy Outcome.  8:e64570. 2013
• Pulsed Electromagnetic Fields Increased the Anti-Inflammatory Effect of A2A and A3 Adenosine Receptors in Human T/C-28a2 Chondrocytes and hFOB 1.19 Osteoblasts.  8. 2013
• Stimulus-Evoked Calcium Transients in Somatosensory Cortex Are Temporarily Inhibited by a Nearby Microhemorrhage.  8:e65663. 2013
• Age-Specific Gene Expression Signatures for Breast Tumors and Cross-Species Conserved Potential Cancer Progression Markers in Young Women.  8:e63204. 2013
• Clinical Adjuvant Combinations Stimulate Potent B-Cell Responses In Vitro by Activating Dermal Dendritic Cells.  8:e63785. 2013
• In silico Driven Redesign of a Clinically Relevant Antibody for the Treatment of GD2 Positive Tumors.  8:e63359. 2013
• Gold Nanoparticle Delivery of Modified CpG Stimulates Macrophages and Inhibits Tumor Growth for Enhanced Immunotherapy.  8:e63550. 2013
• A DTI-Based Template-Free Cortical Connectome Study of Brain Maturation.  8:e63310. 2013
• Increased Tc22 and Treg/CD8 Ratio Contribute to Aggressive Growth of Transplant Associated Squamous Cell Carcinoma.  8:e62154. 2013
• Variability of HIV-1 Genomes among Children and Adolescents from São Paulo, Brazil.  8:e62552. 2013
• A Novel Approach for Characterizing Microsatellite Instability in Cancer Cells.  8:e63056. 2013
• Age-Specific Signatures of Glioblastoma at the Genomic, Genetic, and Epigenetic Levels.  8:e62982. 2013
• Prominin 1/CD133 Endothelium Sustains Growth of Proneural Glioma.  8:e62150. 2013
• Gastrointestinal Stromal Tumors, Somatic Mutations and Candidate Genetic Risk Variants.  8:e62119. 2013
• Design and Initial Results of a Multi-Phase Randomized Trial of Ceftriaxone in Amyotrophic Lateral Sclerosis.  8:e61177. 2013
• EZH2 Mutations Are Related to Low Blast Percentage in Bone Marrow and -7/del(7q) in De Novo Acute Myeloid Leukemia.  8:e61341. 2013
• Genome-Wide RNAi Screening Identifies Genes Inhibiting the Migration of Glioblastoma Cells.  8:e61915. 2013
• Recombinant Human Growth Hormone and Rosiglitazone for Abdominal Fat Accumulation in HIV-Infected Patients with Insulin Resistance: A Randomized, Double-Blind, Placebo-Controlled, Factorial Trial.  8:e61160. 2013
• CD19 CAR-Targeted T Cells Induce Long-Term Remission and B Cell Aplasia in an Immunocompetent Mouse Model of B Cell Acute Lymphoblastic Leukemia.  8:e61338. 2013
• FXR Agonist INT-747 Upregulates DDAH Expression and Enhances Insulin Sensitivity in High-Salt Fed Dahl Rats.  8:e60653. 2013
• Chimeric HIV-1 Envelope Glycoproteins with Potent Intrinsic Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Activity*.  8:e60126. 2013
• Impaired Endothelial Progenitor Cell Mobilization and Dysfunctional Bone Marrow Stroma in Diabetes Mellitus.  8:e60357. 2013
• Derivation of Multivariate Syndromic Outcome Metrics for Consistent Testing across Multiple Models of Cervical Spinal Cord Injury in Rats.  8:e59712. 2013
• A Synergetic Screening Approach with Companion Effector for Combination Therapy: Application to Retinoblastoma.  8:e59156. 2013
• Phase II Study Evaluating 2 Dosing Schedules of Oral Foretinib (GSK1363089), cMET/VEGFR2 Inhibitor, in Patients with Metastatic Gastric Cancer.  8:e54014. 2013
• United States Acculturation and Cancer Patients' End-of-Life Care.  8:e58663. 2013
• Emergence and Diversification of Dengue 2 Cosmopolitan Genotype in Pakistan, 2011.  8:e56391. 2013
• Ablation of BRaf Impairs Neuronal Differentiation in the Postnatal Hippocampus and Cerebellum.  8:e58259. 2013
• Fmr1 Transcript Isoforms: Association with Polyribosomes; Regional and Developmental Expression in Mouse Brain.  8:e58296. 2013
• Long-Term Post-Stroke Changes Include Myelin Loss, Specific Deficits in Sensory and Motor Behaviors and Complex Cognitive Impairment Detected Using Active Place Avoidance.  8:e57503. 2013
• Children's Medicines in Tanzania: A National Survey of Administration Practices and Preferences.  8:e58303. 2013
• Targeted Deletion of Fibrinogen Like Protein 1 Reveals a Novel Role in Energy Substrate Utilization.  8:e58084. 2013
• Effect of Linezolid on Clinical Severity and Pulmonary Cytokines in a Murine Model of Influenza A and Staphylococcus aureus Coinfection.  8:e57483. 2013
• CD57 Expression and Cytokine Production by T Cells in Lesional and Unaffected Skin from Patients with Psoriasis.  8:e52144. 2013
• Cell-Type-Specific Predictive Network Yields Novel Insights into Mouse Embryonic Stem Cell Self-Renewal and Cell Fate.  8:e56810. 2013
• Early and Efficient Detection of Mycobacterium tuberculosis in Sputum by Microscopic Observation of Broth Cultures.  8:e57527. 2013
• Detection of Amyloid Plaques Targeted by Bifunctional USPIO in Alzheimer's Disease Transgenic Mice Using Magnetic Resonance Microimaging.  8:e57097. 2013
• NHE isoform switching and KChIP2 upregulation in aging porcine atria.  8:e82951. 2013
• Identification of Special AT-Rich Sequence Binding Protein 1 as a Novel Tumor Antigen Recognized by CD8⁺ T Cells: Implication for Cancer Immunotherapy.  8:e56730. 2013
• Adenovirus-Based Vaccine with Epitopes Incorporated in Novel Fiber Sites to Induce Protective Immunity against Pseudomonas aeruginosa.  8:e56996. 2013
• High-Fidelity Tissue Engineering of Patient-Specific Auricles for Reconstruction of Pediatric Microtia and Other Auricular Deformities.  8:e56506. 2013
• N-3 Fatty Acid Rich Triglyceride Emulsions Are Neuroprotective after Cerebral Hypoxic-Ischemic Injury in Neonatal Mice.  8:e56233. 2013
• Functional Pathway Analysis Using SCNP of FLT3 Receptor Pathway Deregulation in AML Provides Prognostic Information Independent from Mutational Status.  8:e56714. 2013
• Latitudinal Variations in Seasonal Activity of Influenza and Respiratory Syncytial Virus (RSV): A Global Comparative Review.  8:e54445. 2013
• Proton Pump Inhibitor Use in the U.S. Ambulatory Setting, 2002-2009.  8:e56060. 2013
• Intravenous tPA Therapy Does Not Worsen Acute Intracerebral Hemorrhage in Mice.  8. 2013
• Candidate Sequence Variants and Fetal Hemoglobin in Children with Sickle Cell Disease Treated with Hydroxyurea.  8:e55709. 2013
• The Quiescin Sulfhydryl Oxidase (hQSOX1b) Tunes the Expression of Resistin-Like Molecule Alpha (RELM-α or mFIZZ1) in a Wheat Germ Cell-Free Extract.  8:e55621. 2013
• Accumulation of Intraneuronal β-Amyloid 42 Peptides Is Associated with Early Changes in Microtubule-Associated Protein 2 in Neurites and Synapses.  8:e51965. 2013
• Genetic and Pharmacological Targeting of CSF-1/CSF-1R Inhibits Tumor-Associated Macrophages and Impairs BRAF-Induced Thyroid Cancer Progression.  8:e54302. 2013
• Understanding the Potential Impact of a Combination HIV Prevention Intervention in a Hyper-Endemic Community.  8:e54575. 2013
• A Virtual Retina for Studying Population Coding.  8:e53363. 2013
• A Homogeneous, High-Throughput Assay for Phosphatidylinositol 5-Phosphate 4-Kinase with a Novel, Rapid Substrate Preparation.  8:e54127. 2013
• Variability of Inducible Expression across the Hematopoietic System of Tetracycline Transactivator Transgenic Mice.  8:e54009. 2013
• Human Embryonic Stem Cell Derived Mesenchymal Progenitors Express Cardiac Markers but Do Not Form Contractile Cardiomyocytes.  8. 2013
• Long-Term In Vivo Imaging of Multiple Organs at the Single Cell Level.  8:e52087. 2013
• A Critical Regulatory Role for Macrophage Migration Inhibitory Factor in Hyperoxia-Induced Injury in the Developing Murine Lung.  8. 2013
• The impact of insurance status on the outcomes after aneurysmal subarachnoid hemorrhage..  8:e78047. 2013
• In Vivo Imaging Enables High Resolution Preclinical Trials on Patients' Leukemia Cells Growing in Mice.  7:e52798. 2012
• SRC-2 Coactivator Deficiency Decreases Functional Reserve in Response to Pressure Overload of Mouse Heart.  7:e53395. 2012
• Depressive Symptoms and Cardiovascular Health by the American Heart Association's Definition in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study.  7:e52771. 2012
• Differential Expression of CD96 Surface Molecule Represents CD8⁺T Cells with Dissimilar Effector Function during HIV-1 Infection.  7:e51696. 2012
• Associations between Antibodies to a Panel of Plasmodium falciparum Specific Antigens and Response to Sub-Optimal Antimalarial Therapy in Kampala, Uganda.  7:e52571. 2012
• MR Imaging Features of Gadofluorine-Labeled Matrix-Associated Stem Cell Implants in Cartilage Defects.  7:e49971. 2012
• Reduced Proficiency in Homologous Recombination Underlies the High Sensitivity of Embryonal Carcinoma Testicular Germ Cell Tumors to Cisplatin and Poly (ADP-Ribose) Polymerase Inhibition.  7:e51563. 2012
• Oligo- and Polymetastatic Progression in Lung Metastasis(es) Patients Is Associated with Specific MicroRNAs.  7:e50141. 2012
• Histone Demethylase Jumonji D3 (JMJD3) as a Tumor Suppressor by Regulating p53 Protein Nuclear Stabilization.  7:e51407. 2012
• A Synthetic Form of Frizzled 8-Associated Antiproliferative Factor Enhances p53 Stability through USP2a and MDM2.  7:e50392. 2012
• Exome sequencing of only seven Qataris identifies potentially deleterious variants in the Qatari population..  7:e47614. 2012
• G-cimp status prediction of glioblastoma samples using mRNA expression data..  7:e47839. 2012
• Immunohistochemical detection of MYC-driven diffuse large B-cell lymphomas..  7:e33813. 2012
• Bifidobacterium breve with α-Linolenic Acid and Linoleic Acid Alters Fatty Acid Metabolism in the Maternal Separation Model of Irritable Bowel Syndrome.  7:e48159. 2012
• CD4+ Cells Regulate Fibrosis and Lymphangiogenesis in Response to Lymphatic Fluid Stasis.  7:e49940. 2012
• Dysregulation of IRP1-Mediated Iron Metabolism Causes Gamma Ray-specific Radioresistance in Leukemia Cells.  7:e48841. 2012
• Somatic Mutations of PIK3R1 Promote Gliomagenesis.  7:e49466. 2012
• Simultaneous Detection and Differentiation of Human Papillomavirus Genotypes 6, 11, 16 and 18 by AllGlo Quadruplex Quantitative PCR.  7:e48972. 2012
• The Biological Variation of N-Terminal Pro-Brain Natriuretic Peptide in Postmenopausal Women with Type 2 Diabetes: A Case Control Study.  7:e47191. 2012
• Caprylic Triglyceride as a Novel Therapeutic Approach to Effectively Improve the Performance and Attenuate the Symptoms Due to the Motor Neuron Loss in ALS Disease.  7:e49191. 2012
• The Relative Influences of Phosphometabolites and pH on Action Potential Morphology during Myocardial Reperfusion: A Simulation Study.  7:e47117. 2012
• Pregnancy Induces Transcriptional Activation of the Peripheral Innate Immune System and Increases Oxidative DNA Damage among Healthy Third Trimester Pregnant Women.  7:e46736. 2012
• Chronic Medical Conditions and Risk of Sepsis.  7:e48307. 2012
• BCL2A1a Over-Expression in Murine Hematopoietic Stem and Progenitor Cells Decreases Apoptosis and Results in Hematopoietic Transformation.  7:e48267. 2012
• Utility of a PI3K/mTOR Inhibitor (NVP-BEZ235) for Thyroid Cancer Therapy.  7:e46726. 2012
• Computational Modeling Reveals Dendritic Origins of GABAA-Mediated Excitation in CA1 Pyramidal Neurons.  7. 2012
• Efficiency of Immunotoxin Cytotoxicity Is Modulated by the Intracellular Itinerary.  7:e47320. 2012
• Autoantibodies Produced at the Site of Tissue Damage Provide Evidence of Humoral Autoimmunity in Inclusion Body Myositis.  7:e46709. 2012
• Regulation of a Vascular Plexus by gata4 Is Mediated in Zebrafish through the Chemokine sdf1a.  7:e46844. 2012
• AZD1480 Blocks Growth and Tumorigenesis of RET- Activated Thyroid Cancer Cell Lines.  7:e46869. 2012
• Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy.  7:e46191. 2012
• A High Degree of LINE-1 Hypomethylation Is a Unique Feature of Early-Onset Colorectal Cancer.  7:e45357. 2012
• Age-Related Expansion of Tim-3 Expressing T Cells in Vertically HIV-1 Infected Children.  7:e45733. 2012
• Extended Spectrum Beta-Lactamase-Producing Enterobacteriaceae in International Travelers and Non-Travelers in New York City.  7:e45141. 2012
• Identification of Prostate-Specific G-Protein Coupled Receptor as a Tumor Antigen Recognized by CD8⁺ T Cells for Cancer Immunotherapy.  7:e45756. 2012
• Combined, Sequential Intravenous and Intra-Arterial Chemotherapy (Bridge Chemotherapy) for Young Infants with Retinoblastoma.  7:e44322. 2012
• Human Lung Cancer Cells Grown in an Ex Vivo 3D Lung Model Produce Matrix Metalloproteinases Not Produced in 2D Culture.  7. 2012
• Quantitative Analysis of Monocyte Subpopulations in Murine Atherosclerotic Plaques by Multiphoton Microscopy.  7:e44823. 2012
• An Integrated Genomic and Expression Analysis of 7q Deletion in Splenic Marginal Zone Lymphoma.  7:e44997. 2012
• Graft versus Host Disease in the Bone Marrow, Liver and Thymus Humanized Mouse Model.  7:e44664. 2012
• Complex Structure of Engineered Modular Domains Defining Molecular Interaction between ICAM-1 and Integrin LFA-1.  7:e44124. 2012
• Early Reduction of Microglia Activation by Irradiation in a Model of Chronic Glaucoma.  7:e43602. 2012
• A comparison of EGFR mutation testing methods in lung carcinoma: Direct sequencing, real-time PCR and immunohistochemistry.  7:e43842. 2012
• Imaging characteristics, tissue distribution, and spread of a novel oncolytic vaccinia virus carrying the human sodium iodide symporter.  7:e41647. 2012
• Comparison of 6q25 breast cancer hits from Asian and European genome wide association studies in the Breast Cancer Association consortium (BCAC).  7:e42380. 2012
• Human endogenous retrovirus expression is inversely associated with chronic immune activation in HIV-1 infection.  7:e41021. 2012
• Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.  7:e42756. 2012
• GLI2 regulates TGF-β1 in human CD4+ T cells: Implications in cancer and HIV pathogenesis.  7:e40874. 2012
• Regulation of nuclear factor κB (NF-κB) transcriptional activity via p65 acetylation by the chaperonin containing TCP1 (CCT).  7:e42020. 2012
• Development of a high-throughput assay for identifying inhibitors of TBK1 and IKKε.  7:e41494. 2012
• Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation.  7:e41865. 2012
• Inflammation drives dysbiosis and bacterial invasion in murine models of ileal Crohn's Disease.  7:e41594. 2012
• Activation of soluble adenylyl cyclase protects against secretagogue stimulated zymogen activation in rat pancreaic acinar cells.  7:e41320. 2012
• Multi-center evaluation of post-operative morbidity and mortality after optimal cytoreductive surgery for advanced ovarian cancer.  7:e39415. 2012
• Comparison of wtc dust size on macrophage inflammatory cytokine release in vivo and in vitro.  7:e40016. 2012
• Clinical application of cine-MRI in the visual assessment of mitral regurgitation compared to echocardiography and cardiac catheterization.  7:e40491. 2012
• Genome-wide detection of genes targeted by Non-Ig somatic hypermutation in lymphoma.  7:e40332. 2012
• Mouse transgenesis in a single locus with independent regulation for multiple fluorophores.  7:e40511. 2012
• Four loci explain 83% of size variation in the horse.  7:e39929. 2012
• Limitations of the human reference genome for personalized genomics.  7:e40294. 2012
• Impact of combined mTOR and MEK inhibition in uveal melanoma is driven by tumor genotype.  7:e40439. 2012
• A novel survival-based tissue microarray of pancreatic cancer validates muc1 and mesothelin as biomarkers.  7:e40157. 2012
• Masstrix reloaded: Combined analysis and visualization of tran-scriptome and metabolome data.  7. 2012
• Tim-3 negatively regulates cytotoxicity in exhausted CD8⁺T cells in HIV infection.  7:e40146. 2012
• Absence of Ca²⁺-induced mitochondrial permeability transition but presence of bongkrekate-sensitive nucleotide exchange in C. crangon and P. serratus.  7:e39839. 2012
• Breast cancer risk and 6q22.33: Combined results from breast cancer association consortium and consortium of investigators on modifiers of brca1/2.  7:e35706. 2012
• Influence of HAART on alternative reading frame immune responses over the course of HIV-1 infection.  7:e39311. 2012
• Radiation impairs perineural invasion by modulating the nerve microenvironment.  7:e39925. 2012
• Γ-H2AX kinetics as a novel approach to high content screening for small molecule radiosensitizers.  7:e38465. 2012
• Body fat free mass is associated with the serum metabolite profile in a population-based study.  7:e40009. 2012
• Phase II trial of concurrent sunitinib and image-guided radiotherapy for oligometastases.  7:e36979. 2012
• Characterization of Plasmodium falciparum Adenylyl Cyclase-β and its role in Erythrocytic stage parasites.  7:e39769. 2012
• Fast, automated implementation of temporally precise blind deconvolution of multiphasic excitatory postsynaptic currents.  7:e38198. 2012
• Line-scanning particle image velocimetry: An optical approach for quantifying a wide range of blood flow speeds in live animals.  7:e38590. 2012
• Statistics of weighted brain networks reveal hierarchical organization and gaussian degree distribution.  7:e35029. 2012
• Untargeted plasma metabolite profiling reveals the broad systemic consequences of xanthine oxidoreductase inactivation in mice.  7:e37149. 2012
• DNA fragmentation simulation method (FSM) and fragment size matching improve aCGH performance of FFPE tissues.  7:e38881. 2012
• Host genes related to Paneth cells and xenobiotic metabolism are associated with shifts in human ileum-associated microbial composition.  7:e30044. 2012
• A BAX/BAK and cyclophilin D-independent intrinsic apoptosis pathway.  7:e37782. 2012
• Mesenchymal cell interaction with ovarian cancer cells triggers pro-metastatic properties.  7:e38340. 2012
• Multiple SNPs in intron 41 of thyroglobulin gene are associated with autoimmune thyroid disease in the Japanese population.  7:e37501. 2012
• M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection.  7. 2012
• Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) γ activators and Pan-PPAR partial agonists.  7:e36297. 2012
• Innate immune response of human Plasmacytoid dendritic cells to poxvirus infection is subverted by vaccinia E3 via its Z-DNA/RNA binding domain.  7:e36823. 2012
• The role of TNF-α in mice with type 1- and 2- diabetes.  7:e33254. 2012
• Loss of the urothelial differentiation marker FOXA1 is associated with high grade, late stage bladder cancer and increased tumor proliferation.  7. 2012
• Cardiomyopathy and response to enzyme replacement therapy in a male mouse model for fabry disease.  7:e33743. 2012
• Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders.  7. 2012
• Concordant signaling pathways produced by pesticide exposure in mice correspond to pathways identified in human parkinson's disease.  7:e36191. 2012
• Functional characterization of circulating tumor cells with a prostate-cancer-specific microfluidic device.  7:e35976. 2012
• Shh signaling from the nucleus pulposus is required for the postnatal growth and differentiation of the mouse intervertebral disc.  7:e35944. 2012
• Ophthalmic artery chemosurgery for less advanced intraocular retinoblastoma: Five year review.  7:e34120. 2012
• Assigning backbone NMR resonances for full length tau isoforms: Efficient compromise between manual assignments and reduced dimensionality.  7:e34679. 2012
• Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screening.  7:e34414. 2012
• Repertoire enhancement with adoptively transferred female lymphocytes controls the growth of pre-implanted murine prostate cancer.  7:e35222. 2012
• Host immune transcriptional profiles reflect the variability in clinical disease manifestations in patients with staphylococcus aureus infections.  7:e34390. 2012
• Changes in prefrontal-limbic function in major depression after 15 months of long-term psychotherapy.  7:e33745. 2012
• Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients.  7:e32345. 2012
• Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: Relationship to HER2/neu expression in human and mouse.  7:e33421. 2012
• Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors.  7:e34354. 2012
• Acute histologic chorioamnionitis at term: Nearly always noninfectious.  7:e31819. 2012
• Normalization of the lymph node T cell stromal microenvironment in lpr/lpr mice is associated with SU5416-induced reduction in autoantibodies.  7:e32828. 2012
• Intentional weight loss and dose reductions of anti-diabetic medications - a retrospective cohort study.  7:e32395. 2012
• Interleukin-1 stimulates ADAM17 through a mechanism independent of its cytoplasmic domain or phosphorylation at threonine 735.  7. 2012
• The effect of the visual context in the recognition of symbolic gestures.  7:e29644. 2012
• Quantitative modeling of Cerenkov light production efficiency from medical radionuclides.  7:e31402. 2012
• Improved control of tuberculosis and activation of macrophages in mice lacking protein kinase R.  7:e30512. 2012
• Towards the "baby connectome": Mapping the structural connectivity of the newborn brain.  7:e31029. 2012
• Transcriptional analysis of shewanella oneidensis MR-1 with an electrode compared to Fe(III)citrate or oxygen as terminal electron acceptor.  7:e30827. 2012
• Novel use of surveillance data to detect HIV-infected persons with sustained high viral load and durable virologic suppression in New York City.  7:e29679. 2012
• Transcription factor FoxO1 is essential for enamel biomineralization.  7:e30357. 2012
• Novel strategy for selection of monoclonal antibodies against highly conserved antigens: Phage library panning against ephrin-B2 displayed on yeast.  7:e30680. 2012
• Circulating angiopoietin-2 as a biomarker in ANCA-associated vasculitis.  7:e30197. 2012
• Association of differentiation state of CD4+ T cells and disease progression in HIV-1 perinatally infected children.  7:e29154. 2012
• Protein phosphatase 2A mediates dormancy of glioblastoma multiforme-derived tumor stem-like cells during hypoxia.  7:e30059. 2012
• Intra- and inter-tumor heterogeneity of BRAF V600Emutations in primary and metastatic melanoma.  7:e29336. 2012
• Copy number variation analysis of matched ovarian primary tumors and peritoneal metastasis.  6:e28561. 2011
• Socioeconomic status and incident type 2 diabetes mellitus: Data from the women's health study.  6:e27670. 2011
• Endemic acinetobacter baumannii in a New York hospital.  6:e28566. 2011
• A brain region-specific predictive gene map for autism derived by profiling a reference gene set.  6:e28431. 2011
• Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense.  6:e28149. 2011
• SHIV-162P3 infection of rhesus macaques given maraviroc gel vaginally does not involve resistant viruses.  6. 2011
• Novel Retinoic Acid Receptor Alpha Agonists for Treatment of Kidney Disease.  6:e27945. 2011
• Endoplasmic reticulum remodeling tunes IP3-dependent Ca2+ release sensitivity.  6:e27928. 2011
• Fitness conferred by BCR-ABL kinase domain mutations determines the risk of pre-existing resistance in chronic myeloid leukemia.  6:e27682. 2011
• Stat3 mediates expression of autotaxin in breast cancer.  6:e27851. 2011
• An Inter-Laboratory validation of a real time PCR assay to measure host excretion of bacterial pathogens, particularly of Mycobacterium bovis.  6:e27369. 2011
• Serum microRNA expression profile distinguishes enterovirus 71 and coxsackievirus 16 infections in patients with hand-foot-and-mouth disease.  6:e27071. 2011
• Excess circulating alternatively activated myeloid (M2) cells accelerate ALS progression while inhibiting experimental autoimmune encephalomyelitis.  6:e26921. 2011
• An in vivo platform for tumor biomarker assessment.  6:e26722. 2011
• C-kit-mediated functional positioning of stem cells to their niches is essential for maintenance and regeneration of adult hematopoiesis.  6:e26918. 2011
• Cortical microhemorrhages cause local inflammation but do not trigger widespread dendrite degeneration.  6:e26612. 2011
• Purinergic signaling induces cyclooxygenase-1-dependent prostanoid synthesis in microglia: Roles in the outcome of excitotoxic brain injury.  6:e25916. 2011
• A system for performing high throughput assays of synaptic function.  6:e25999. 2011
• Rem2-targeted shRNAs reduce frequency of miniature excitatory postsynaptic currents without altering voltage-gated Ca 2+ currents.  6:e25741. 2011
• A time-series method for automated measurement of changes in mitotic and interphase duration from time-lapse movies.  6:e25511. 2011
• Transgene excision has no impact on in vivo integration of human iPS derived neural precursors.  6:e24687. 2011
• Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers.  6:e24987. 2011
• The wiring economy principle: Connectivity determines anatomy in the human brain.  6:e14832. 2011
• Altered development of NKT cells, γδ T cells, CD8 T cells and NK cells in a PLZF deficient patient.  6:e24441. 2011
• SMURF1 amplification promotes invasiveness in pancreatic cancer.  6:e23924. 2011
• Sodium coupled bicarbonate influx regulates intracellular and apical pH in cultured rat caput epididymal epithelium.  6:e22283. 2011
• Loss of cytoplasmic CDK1 predicts poor survival in human lung cancer and confers chemotherapeutic resistance.  6:e23849. 2011
• The Candida albicans Ku70 modulates telomere length and structure by regulating both telomerase and recombination.  6:e23732. 2011
• Adherence of pharmaceutical advertisements in medical journals to FDA guidelines and content for safe prescribing.  6:e23336. 2011
• The accuracy of the electrocardiogram during exercise stress test based on heart size.  6:e23044. 2011
• Hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network.  6:e22649. 2011
• A phase iia randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade RAD5 HIV-1 vaccine boost in healthy adults (HVTN204).  6:e21225. 2011
• Oral microbiome profiles: 16s rRNA pyrosequencing and microarray assay comparison.  6:e22788. 2011
• Biologic phenotyping of the human small airway epithelial response to cigarette smoking.  6:e22798. 2011
• Frequency domain analysis reveals external periodic fluctuations can generate sustained p53 oscillation.  6:e22852. 2011
• Imaging of alkaline phosphatase activity in bone tissue.  6:e22608. 2011
• An integrative view of mechanisms underlying generalized Apike-And-Wave epileptic seizures and its implication on optimal therapeutic treatments.  6:e22440. 2011
• Catalytic and non-catalytic roles for the mono-ADP-ribosyltransferase arr in the mycobacterial DNA damage response.  6:e21807. 2011
• P16 INK4a positively regulates cyclin D1 and E2F1 through negative control of auf1.  6:e21111. 2011
• Immunodominance of HIV-1 specific CD8+ T-cell responses is related to disease progression rate in vertically infected adolescents.  6:e21135. 2011
• Out-of-frame T cell receptor beta transcripts are eliminated by multiple pathways In Vivo.  6:e21627. 2011
• Rex shunt preoperative imaging: Diagnostic capability of imaging modalities.  6:e22222. 2011
• War and bereavement: Consequences for mental and physical distress.  6:e22140. 2011
• Differences between human plasma and serum metabolite profiles.  6:e21230. 2011
• Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation.  6:e21611. 2011
• Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression.  6:e20605. 2011
• Detection of intra-tumor self antigen recognition during melanoma tumor progression in mice using advanced multimode confocal/two photon microscope.  6:e21214. 2011
• Mitochondrial ceramide-rich macrodomains functionalize bax upon irradiation.  6:e19783. 2011
• Human endogenous retrovirus K106 (HERV-k106) was infectious after the emergence of anatomically modern humans.  6:e20234. 2011
• A tri-marker proliferation index predicts biochemical recurrence after surgery for prostate cancer.  6:e20293. 2011
• Estimating survival in patients with operable skeletal metastases: An application of a Bayesian belief network.  6:e19956. 2011
• Multizone paper platform for 3D cell cultures.  6:e18940. 2011
• The human airway epithelial basal cell transcriptome.  6:e18378. 2011
• Resistance of renal cell carcinoma to sorafenib is mediated by potentially reversible gene expression.  6:e19144. 2011
• Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice.  6. 2011
• Th17 cells and activated dendritic cells are increased in vitiligo lesions.  6:e18907. 2011
• Assessment of cardiovascular fibrosis using novel fluorescent probes.  6:e19097. 2011
• Down-regulation of the canonical wnt β-catenin pathway in the airway epithelium of healthy smokers and smokers with COPD.  6:e14793. 2011
• Inhibition of anaplastic lymphoma kinase (ALK) activity provides a therapeutic approach for CLTC-ALK-positive human diffuse large B cell lymphomas.  6:e18436. 2011
• Dopaminergic Neuronal loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2.  6:e18568. 2011
• A computational framework discovers new copy number variants with functional importance.  6:e17539. 2011
• Multiple cancer/testis antigens are preferentially expressed in hormone-receptor negative and high-grade breast cancers.  6:e17876. 2011
• Evaluating research and impact: A bibliometric analysis of research by the NIH/NIAID HIV/AIDS clinical trials networks.  6:e17428. 2011
• Lipid nanocapsules loaded with Rhenium-188 reduce tumor progression in a rat hepatocellular carcinoma model.  6:e16926. 2011
• MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors.  6:e17449. 2011
• Phosphodiesterase 4 inhibition reduces innate immunity and improves isoniazid clearance of Mycobacterium tuberculosis in the lungs of infected mice.  6:e17091. 2011
• Critical role of neuropeptides B/W receptor 1 signaling in social behavior and fear memory.  6:e16972. 2011
• Mechanisms of lymphatic regeneration after tissue transfer.  6:e17201. 2011
• Prediction of associations between microRNAs and gene expression in glioma biology.  6:e14681. 2011
• Rituximab therapy reduces organ-specific T cell responses and ameliorates experimental autoimmune encephalomyelitis.  6:e17103. 2011
• Discovery of novel human breast cancer micrornas from deep sequencing data by analysis of pri-microrna secondary structures.  6:e16403. 2011
• The obesity-associated polymorphisms FTO rs9939609 and MC4R rs17782313 and endometrial cancer risk in non-Hispanic white women.  6:e16756. 2011
• A one-dimensional continuum elastic model for membrane-embedded gramicidin dimer dissociation.  6:e15563. 2011
• The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter.  6:e16350. 2011
• Optimizing tactics for use of the U.S. antiviral strategic national stockpile for pandemic influenza.  6. 2011
• DNA methylation of the first exon is tightly linked to transcriptional silencing.  6:e14524. 2011
• Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-Deficient PDGF-driven murine glioblastoma.  6:e14545. 2011
• Aptamer-based multiplexed proteomic technology for biomarker discovery.  5:e15004. 2010
• O-Glycosylation regulates ubiquitination and degradation of the anti-inflammatory protein A20 to accelerate atherosclerosis in diabetic ApoE-null mice.  5:e14240. 2010
• Duplication of the slit3 locus on 5q35.1 predisposes to major depressive disorder.  5:e15463. 2010
• Improving a mother to child HIV transmission programme through health system redesign: Quality improvement, protocol adjustment and resource addition.  5:e13891. 2010
• Metabolic footprint of diabetes: A multiplatform metabolomics study in an epidemiological setting.  5:e13953. 2010
• Notch and MAML-1 Complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.  5:e15034. 2010
• A phase II trial of sorafenib in metastatic melanoma with tissue correlates.  5:e15588. 2010
• Adaptation of group A Streptococcus to human amniotic fluid.  5. 2010
• Altered auditory BOLD response to conspecific birdsong in zebra finches with stuttered syllables.  5:e14415. 2010
• An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma.  5:e9863. 2010
• Genome-wide screen for Mycobacterium tuberculosis genes that regulate host immunity.  5:e15120. 2010
• Large-scale discovery and characterization of protein regulatory motifs in eukaryotes.  5:e14444. 2010
• MicroRNA-Related Cofilin Abnormality in Alzheimer's Disease.  5:e15546. 2010
• Prolonged Application of High Fluid Shear to Chondrocytes Recapitulates Gene Expression Profiles Associated with Osteoarthritis.  5:e15174. 2010
• Simultaneous analysis of multiple mycobacterium tuberculosis knockdown mutants in vitro and in vivo.  5:e15667. 2010
• The complete chloroplast genome sequence of date palm (Phoenix dactylifera L.)..  5:e12762. 2010
• A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-α and MIP1-β, a lack of IL-17, and a Th1-bias in males.  5:e15412. 2010
• A new mouse model to explore therapies for preeclampsia.  5:e13663. 2010
• Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown.  5:e13568. 2010
• Identification of De Novo copy number variants associated with human disorders of sexual development.  5:e15392. 2010
• MicroRNA-integrated and network-embedded gene selection with diffusion distance.  5:e13748. 2010
• Nitrate respiration protects hypoxic Mycobacterium tuberculosisagainst acid- and reactive nitrogen species stresses.  5:e13356. 2010
• Phosphatidylinositol 5-phosphate links dehydration stress to the activity of ARABIDOPSIS TRITHORAX-LIKE factor ATX1.  5:e13396. 2010
• Splice isoforms of the polyglutamine disease protein ataxin-3 exhibit similar enzymatic yet different aggregation properties.  5:e13695. 2010
• Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition.  5:e12707. 2010
• Alphavirus replicon particles expressing TRP-2 provide potent therapeutic effect on melanoma through activation of humoral and cellular immunity.  5:1-8. 2010
• Clostridium perfringens epsilon toxin targets granule cells in the mouse cerebellum and stimulates glutamate release.  5. 2010
• Frequent MAGE mutations in human melanoma.  5:1-7. 2010
• Harnessing naturally occurring tumor immunity: A clinical vaccine trial in prostate cancer.  5:1-12. 2010
• Human MicroRNA oncogenes and tumor suppressors show significantly different biological patterns: From functions to targets.  5:1-7. 2010
• Induction of ER stress in macrophages of tuberculosis granulomas.  5:e12772. 2010
• Skewed distribution of circulating activated natural killer T (NKT) cells in patients with common variable immunodeficiency disorders (CVID).  5:1-8. 2010
• Cholesterol pathways affected by small molecules that decrease sterol levels in niemann-pick type C mutant cells.  5:e12788. 2010
• Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease.  5. 2010
• Endothelial membrane remodeling is obligate for anti-angiogenic radiosensitization during tumor radiosurgery.  5:e12310. 2010
• Bayesian linkage analysis of categorical traits for arbitrary pedigree designs.  5:e12307. 2010
• Deletion of Nhlh2 results in a defective torpor response and reduced beta adrenergic receptor expression in adipose tissue.  5:e12324. 2010
• Portable, battery-operated, low-cost, bright field and fluorescence microscope.  5:e11890. 2010
• Integrative genome comparison of primary and metastatic melanomas.  5:e10770. 2010
• Molecular targeting of carbonic anhydrase ix in mice with hypoxic HT29 colorectal tumor xenografts.  5:e10857. 2010
• Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation.  5:e10436. 2010
• Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin.  5:e10504. 2010
• Genetic analysis of the early natural history of epithelial ovarian carcinoma.  5:e10358. 2010
• A forward chemical screen in zebrafish identifies a retinoic acid derivative with receptor specificity.  5:e10004. 2010
• Evaluation of the Psoriasis Transcriptome across Different Studies by Gene Set Enrichment Analysis (GSEA).  5:e10247. 2010
• Intelligence in williams syndrome is related to STX1A, which encodes a component of the presynaptic SNARE complex.  5:e10292. 2010
• Rapid Progressing Allele HLA-B35 Px Restricted Anti-HIV-1 CD8+ T Cells Recognize Vestigial CTL Epitopes.  5:e10249. 2010
• The onconeural antigen cdr2 is a novel APC/C target that acts in mitosis to regulate C-Myc target genes in mammalian tumor cells.  5:e10045. 2010
• Clinically relevant characterization of lung adenocarcinoma subtypes based on cellular pathways: An international validation study.  5:e11712. 2010
• Proinflammatory phenotype and increased caveolin-1 in alveolar macrophages with silenced CFTR mRNA.  5:e11004. 2010
• Rates and reasons for early change of first HAART in HIV-1-infected patients in 7 sites throughout the Caribbean and Latin America.  5:e10490. 2010
• The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways.  5:e9633. 2010
• The shifting demographic landscape of pandemic influenza.  5:e9360. 2010
• Prolonged graft survival in older recipient mice is determined by impaired effector T-cell but intact regulatory T-cell responses.  5:e9232. 2010
• Measuring the pharmacodynamic effects of a novel Hsp90 inhibitor on HER2/ neu expression in mice using 89Zr-DFO-trastuzumab.  5:e8859. 2010
• A phase II trial of the epothilone B analog ixabepilone (BMS-247550) in patients with metastatic melanoma.  5:e8714. 2010
• Human CD4⁺ memory T cells can become CD4⁺IL-9 ⁺ T cells.  5:e8706. 2010
• Prokayrotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis.  5:e8589. 2010
• Intelligence in Williams Syndrome is related to STX1A, which encodes a component of the presynaptic SNARE complex..  5:e10292. 2010
• Cross Species Genomic Analysis Identifies a Mouse Model as Undifferentiated Pleomorphic Sarcoma/Malignant Fibrous Histiocytoma.  4:e8075. 2009
• Down regulation of genes involved in T cell polarity and motility during the induction of heart allograft tolerance by allochimeric MHC I.  4:e8020. 2009
• Induction of ovarian leiomyosarcomas in mice by conditional inactivation of Brca1 and p53.  4:e8404. 2009
• Long-term stability of visual pattern selective responses of monkey temporal lobe neurons.  4:e8222. 2009
• Modulation of cell surface protein free thiols: A potential novel mechanism of action of the sesquiterpene lactone parthenolide.  4:e8115. 2009
• Self-reported and actual beta-blocker prescribing for heart failure patients: Physician predictors.  4:e8522. 2009
• Smoking is associated with shortened airway Cilia.  4:e8157. 2009
• Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis.  4:e7955. 2009
• Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations.  4:e7752. 2009
• Origins of an intrinsic hippocampal EEG pattern.  4:e7761. 2009
• Metabolomic profiling in LRRK2-related Parkinson's disease.  4:e7551. 2009
• Enteric neural crest differentiation in ganglioneuromas implicates hedgehog signaling in peripheral neuroblastic tumor pathogenesis.  4:e7491. 2009
• Physico-chemical evaluation of rationally designed melanins as novel nature-inspired radioprotectors.  4:e7229. 2009
• Rhabdomyolysis in community acquired bacterial sepsis - A retrospective cohort study.  4:e7182. 2009
• Empirical study of data sharing by authors publishing in PLoS journals.  4:e7078. 2009
• Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders.  4:e7100. 2009
• Comparison of the immunomodulatory properties of three probiotic strains of Lactobacilli using complex culture systems: Prediction for in vivo efficacy.  4:e7056. 2009
• NAChRs mediate human embryonic stem cell-derived endothelial cells: Proliferation, apoptosis, and angiogenesis.  4:e7040. 2009
• Activation of PyMT in β cells induces irreversible hyperplasia, but oncogene-dependent acinar cell carcinomas when activated in pancreatic progenitors.  4:e6932. 2009
• Systems-level modeling of cancer-fibroblast interaction.  4:e6888. 2009
• The influence of radiographic phenotype and smoking status on peripheral blood biomarker patterns in chronic obstructive pulmonary disease.  4:e6865. 2009
• Identification of a human cyclin D1-derived peptide that induces human cytotoxic CD4 T cells.  4:e6730. 2009
• Multiparameter phospho-flow analysis of lymphocytes in early rheumatoid arthritis: Implications for diagnosis and monitoring drug therapy.  4:e6703. 2009
• A decreased frequency of regulatory T cells in patients with common variable immunodeficiency.  4:e6269. 2009
• Structure/function analysis of PARP-1 in oxidative and nitrosative stress-induced monomeric ADPR formation.  4:e6339. 2009
• Transcriptome adaptation of group B Streptococcus to growth in human amniotic fluid.  4:e6114. 2009
• Intragraft selection of the T cell receptor repertoire by class I MHC sequences in tolerant recipients.  4:e6076. 2009
• p63 promotes cell survival through fatty acid synthase.  4:e5877. 2009
• Tolerance to the neuron-specific paraneoplastic HuD antigen.  4:e5739. 2009
• Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription.  4:e5757. 2009
• Latherin: A surfactant protein of horse sweat and saliva.  4. 2009
• Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo.  4:e5683. 2009
• Challenges for routine health system data management in a large public programme to prevent mother-to-child HIV transmission in South Africa.  4:e5483. 2009
• Enhanced monocyte response and decreased central memory T cells in children with invasive Staphylococcus aureus infections.  4:e5446. 2009
• Qualitative and quantitative detection of Chlamydophila pneumoniae DNA in cerebrospinal fluid from multiple sclerosis patients and controls.  4:e5200. 2009
• Pattern-selection based power analysis and discrimination of low- and high-grade myelodysplastic syndromes study using SNP arrays.  4:e5054. 2009
• Real-time imaging of HIF-1α stabilization and degredation.  4:e5077. 2009
• Genome-wide hypomethylation in head and neck cancer is more pronounced in HPV-negative tumors and is associated with genomic instability.  4:e4941. 2009
• HIV-1 epidemic in the Caribbean is dominated by subtype B.  4:e4814. 2009
• Imaging of lymph node micrometastases using an oncolytic herpes virus and [18F]FEAU PET.  4:e4789. 2009
• Human T cell leukemia virus reactivation with progression of adult T-cell leukemia-lymphoma.  4:e4420. 2009
• PECAM-independent thioglycollate peritonitis is associated with a locus on murine chromosome 2.  4:e4316. 2009
• IGFBP3 colocalizes with and regulates hypocretin (orexin).  4:e4254. 2009
• PEG minocycline-liposomes ameliorate CNS autoimmune disease.  4:e4151. 2009
• BRAF activation initiates but does not maintain invasive prostate adenocarcinoma.  3:e3949. 2008
• Oncologic trogocytosis of an original stromal cells induces chemoresistance of ovarian tumours.  3:e3894. 2008
• Non-natural and photo-reactive amino acids as biochemical probes of immune function.  3:e3938. 2008
• Metabolic profiling reveals distinct variations linked to nicotine consumption in humans - First results from the KORA study.  3:e3863. 2008
• Improving outcomes in infants of HIV-infected women in a developing country setting.  3:e3723. 2008
• HIV-specific T-cells accumulate in the liver in HCV/HIV co-infection.  3:e3454. 2008
• Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease.  3:e3316. 2008
• Somatic 'soluble' adenylyl cyclase isoforms are unaffected in Sacytm1Lex/Sacytm1Lex 'knockout' mice.  3:e3251. 2008
• Functional copy-number alterations in cancer.  3:e3179. 2008
• Breast tumor cells with P13K mutation or HER2 amplification are selectively addicted to Akt signaling.  3:e3065. 2008
• Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth.  3:e2916. 2008
• Meta-analysis of microarray studies reveals a novel hematopoietic progenitor cell signature and demonstrates feasibility of inter-platform data integration.  3:e2965. 2008
• Principles of glomerular organization in the human olfactory bulb - Implications for odor processing.  3:e2640. 2008
• Immunogenecity of modified alkane polymers is mediated through TLR1/2 activation.  3:e2438. 2008
• A tissue biomarker panel predicting systemic progression after PSA recurrence post-definitive prostate cancer therapy.  3:e2318. 2008
• Genital herpes has played a more important role than any other sexually transmitted infection in driving HIV prevalence in Africa.  3:e2230. 2008
• Understanding the impact of male circumcision interventions on the spread of HIV in southern Africa.  3:e2212. 2008
• Ionic mechanisms of endogenous bursting in CA3 hippocampal pyramidal neurons: A model study.  3:e2056. 2008
• An integrative genomic and epigenomic approach for the study of transcriptional regulation.  3:e1882. 2008
• Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP.  3:e1746. 2008
• Ganglion cell adaptability: Does the coupling of horizontal cells play a role?.  3:e1714. 2008
• Mitogen-activated protein kinases regulate susceptibility to ventilator-induced lung injury.  3:e1601. 2008
• Nucleoside analogue reverse transcriptase inhibitors differentially inhibit human LINE-1 retrotransposition.  3:e1547. 2008
• Microbial patterns signaling via toll-like receptors 2 and 5 contribute to epithelial repair, growth and survival.  3:e1393. 2008
• Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway.  2:e1337. 2007
• The complete genome sequence and analysis of the epsilonproteobacterium Arcobacter butzleri.  2:e1358. 2007
• Id1 restrains p21 expression to control endothelial progenitor cell formation.  2:e1338. 2007
• Amyotrophic lateral sclerosis: An emerging era of collaboratie gene discovery.  2:e1254. 2007
• Therapeutic strategy for acute spinal cord contusion injury: cell elimination combined with microsurgical intervention..  2:e565. 2007
• HIV-1/HSV-2 co-infected adults in early HIV-1 infection have elevated CD4+ T cell counts.  2:e1080. 2007
• Optimal signal processing in small stochastic biochemical networks.  2:e1077. 2007
• PET imaging of soluble yttrium-86-labeled carbon nanotubes in mice.  2:e907. 2007
• Development of new mouse lung tumor models expressing EGFR T790M mutants associated with clinical resistance to kinase inhibitors.  2:e810. 2007
• Simple sequence repeats provide a substrate for phenotypic variation in the Neurospora crassa circadian clock.  2:e795. 2007
• Long-term impact of radiation on the stem cell and oligodendrocyte precursors in the brain.  2:e588. 2007
• Ionizing radiation changes the electronic properties of melanin and enhances the growth of melanized fungi.  2:e457. 2007
• Calculation of the free energy and cooperativity of protein folding.  2:e446. 2007
• Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4.  2:e426. 2007
• XSelective alpha-particle mediated depletion of tumor vasculature with vascular normalization.  2:e267. 2007
• Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape.  2:e225. 2007
• Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removal.  1:e102. 2006
• Correction: Type 2 diabetes risk allele loci in the Qatari population (PLoS ONE (2016) 11:7 (e0156834) DOI: 10.1371/journal.pone.0156834).  11:e0161910. 2016
• Correction: Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes.  11:e0160293. 2016
• Correction: Mitochondrial ceramide-rich macrodomains functionalize bax upon irradiation.  10:e0146210. 2015
• Correction: Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice.  10. 2015
• Correction: Folate receptor-α (FOLR1) expression and function in triple negative tumors.  10:e0127133. 2015
• Correction: Continuing a cancer treatment despite tumor growth may be valuable: Sunitinib in renal cell carcinoma as example (PLoS ONE (2014) 9, 5 (e96316) DOI: 10.1371/journal.pone.0096316).  9. 2014
• Correction: Simplification to abacavir/lamivudine + atazanavir maintains viral suppression and improves bone and renal biomarkers in ASSURE, a randomized, open label, non-inferiority trial (PLoS ONE (2014) 9, 5 (e96187) DOI: 10.1371/journal.pone.0096187).  9. 2014
• Correction: Signaling role of prokineticin 2 on the estrous cycle of female mice (PLoS ONE (2014) 9, 3 (e90860) DOI:10.1371/journal.pone.0090860).  9. 2014
• Correction: A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events (PLoS ONE (2014) 9, 1 (e87361) DOI: 10.1371/journal.pone.0087361).  9. 2014
• Correction: Microfluidic generated EGF-Gradients induce chemokinesis of transplantable retinal progenitor cells via the JAK/STAT and PI3Kinase signaling pathways (PLoS ONE).  9. 2014
• Correction: Oligo- and polymetastatic progression in lung metastasis(es) patients is associated with specific microRNAs (PLoS ONE).  8. 2013
• Correction: Computational modeling reveals dendritic origins of GABA A-mediated excitation in CA1 pyramidal neurons (PLoS ONE).  8. 2013
• Correction: CD4+ cells regulate fibrosis and lymphangiogenesis in response to lymphatic fluid stasis (PLoS ONE).  8. 2013
• Correction: Graft versus host disease in the bone marrow, liver and thymus humanized mouse model. (PLoS ONE (2012) 7, 9 (e44664) DOI:10.1371/journal.pone. 0044664).  8. 2013
• An international consensus definition of the wish to hasten death and its related factors 2016
• Hepatitis C virus viremic rate in the Middle East and North Africa: Systematic synthesis, meta-analyses, and meta-regressions 2017
• Cost-effectiveness of adjunct non-pharmacological interventions for osteoarthritis of the knee 2017
• Increased mortality in metal-on-metal versus non-metal-on-metal primary total hip arthroplasty at 10 years and longer follow-up: A systematic review and meta-analysis 2016
• Hepatitis C virus epidemiology in Djibouti, Somalia, Sudan, and Yemen: Systematic review and meta-analysis 2016
• Validation of the stop-bang questionnaire as a screening tool for obstructive sleep apnea among different populations: A systematic review and meta-Analysis 2015
• Prevalence of prostate cancer clinical states and mortality in the United States: Estimates using a dynamic progression model 2015
• Local anesthetic peripheral nerve block adjuvants for prolongation of analgesia: A systematic qualitative review 2015
• The epidemiology of hepatitis C virus in the fertile crescent: Systematic review and meta-analysis 2015
• The effectiveness of different interventions to promote poison prevention behaviours in households with children: A network meta-analysis 2015
• Control group design, contamination and drop-out in exercise oncology trials: A systematic review 2015
• The epidemiology of hepatitis C virus in the maghreb region: Systematic review and Meta-analyses 2015
• Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function 2014
• Influence of control group on effect size in trials of acupuncture for chronic pain: A secondary analysis of an individual patient data meta-analysis 2014
• Genetic polymorphisms of XRCC1 and leukemia risk: A meta-analysis of 19 case-control studies 2013
• Characteristics of Acupuncture Treatment Associated with Outcome: An Individual Patient Meta-Analysis of 17,922 Patients with Chronic Pain in Randomised Controlled Trials 2013
• The effects of dietary intervention on HIV dyslipidaemia: A systematic review and meta-analysis 2012

Identity

ISO Abbreviation

• PLoS One

Linking ISSN

• 1932-6203

Electronic International Standard Serial Number (EISSN)

• 1932-6203