selected publications
- FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1. Molecular cell. 2023 Academic Article GET IT
- Decreased Enterobacteriaceae translocation due to gut microbiota remodeling mediates the alleviation of premature aging by a high-fat diet. Aging cell. 2022 Academic Article GET IT
- Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment. Science signaling. 2022 Review GET IT
- Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression. Nature communications. 2022 Academic Article GET IT
- Suppression of nuclear GSK3 signaling promotes serine/one-carbon metabolism and confers metabolic vulnerability in lung cancer cells. Science advances. 2022 Academic Article GET IT
- SPATA4 improves aging-induced metabolic dysfunction through promotion of preadipocyte differentiation and adipose tissue expansion. Aging cell. 2020 Academic Article GET IT
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Protective Effects of SIRT6 Overexpression against DSS-Induced Colitis in Mice.
Cells.
2020
Academic Article
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Times cited: 18 -
A high-fat diet reverses metabolic disorders and premature aging by modulating insulin and IGF1 signaling in SIRT6 knockout mice.
Aging cell.
2020
Academic Article
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Times cited: 21 -
Pooled CRISPR Screens in Drosophila Cells.
Current protocols in molecular biology.
2019
Academic Article
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Times cited: 10 -
Aging Biomarkers and Novel Targets for Anti-Aging Interventions.
Advances in experimental medicine and biology.
2019
Article
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Times cited: 3 -
A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila.
Developmental cell.
2018
Academic Article
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Times cited: 83 -
Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in Drosophila cells.
eLife.
2018
Academic Article
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Times cited: 49 -
Overexpressed SIRT6 attenuates cisplatin-induced acute kidney injury by inhibiting ERK1/2 signaling.
Kidney international.
2018
Academic Article
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Times cited: 36 -
Aging Kidney and Aging-Related Disease.
Advances in experimental medicine and biology.
2018
Article
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Times cited: 5 -
Improved detection of synthetic lethal interactions in Drosophila cells using variable dose analysis (VDA).
Proceedings of the National Academy of Sciences of the United States of America.
2017
Academic Article
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Times cited: 5 -
Calorie restriction-induced SIRT6 activation delays aging by suppressing NF-κB signaling.
Cell cycle (Georgetown, Tex.).
2016
Academic Article
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Times cited: 85 -
Resveratrol Protects against High-Fat Diet Induced Renal Pathological Damage and Cell Senescence by Activating SIRT1.
Biological & pharmaceutical bulletin.
2016
Academic Article
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Times cited: 17