selected publications
- Single-cell ionic current phenotyping explains stem cell-derived cardiomyocyte action potential morphology. American journal of physiology. Heart and circulatory physiology. 2024 Academic Article GET IT
- Optimization of a Cardiomyocyte Model Illuminates Role of Increased INaL in Repolarization Reserve. American journal of physiology. Heart and circulatory physiology. 2023 Academic Article GET IT
- Rapid ionic current phenotyping (RICP) identifies mechanistic underpinnings of iPSC-CM AP heterogeneity. 2023 GET IT
- Diversity of Cells and Signals in the Cardiovascular System. The Journal of physiology. 2023 Academic Article GET IT
- An in silico-in vitro pipeline for drug cardiotoxicity screening identifies ionic proarrhythmia mechanisms. British journal of pharmacology. 2022 Academic Article GET IT
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Validation of quantitative measure of repolarization reserve as a novel marker of drug induced proarrhythmia.
Journal of molecular and cellular cardiology.
2020
Academic Article
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Times cited: 3 -
Light-Activated Dynamic Clamp Using iPSC-Derived Cardiomyocytes.
Biophysical journal.
2018
Academic Article
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Times cited: 21 -
Global Optimization of Ventricular Myocyte Model to Multi-Variable Objective Improves Predictions of Drug-Induced Torsades de Pointes.
Frontiers in physiology.
2017
Academic Article
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Times cited: 23 -
Regularity of beating of small clusters of embryonic chick ventricular heart-cells: experiment vs. stochastic single-channel population model.
Chaos (Woodbury, N.Y.).
2017
Academic Article
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Times cited: 5 -
Slow [Na+]i dynamics impacts arrhythmogenesis and spiral wave reentry in cardiac myocyte ionic model.
Chaos (Woodbury, N.Y.).
2017
Academic Article
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Times cited: 7 -
Differential roles of two delayed rectifier potassium currents in regulation of ventricular action potential duration and arrhythmia susceptibility.
The Journal of physiology.
2016
Academic Article
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Times cited: 26 -
Illuminating Myocyte-Fibroblast Homotypic and Heterotypic Gap Junction Dynamics Using Dynamic Clamp.
Biophysical journal.
2016
Academic Article
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Times cited: 15 -
Computational Approaches to Understanding the Role of Fibroblast-Myocyte Interactions in Cardiac Arrhythmogenesis.
BioMed research international.
2015
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Times cited: 14 -
Cell-specific cardiac electrophysiology models.
PLoS computational biology.
2015
Academic Article
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Times cited: 76 -
Voltage and calcium dynamics both underlie cellular alternans in cardiac myocytes.
Biophysical journal.
2014
Academic Article
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Times cited: 23 -
Dependence of phase-2 reentry and repolarization dispersion on epicardial and transmural ionic heterogeneity: a simulation study.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.
2014
Academic Article
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Times cited: 20 -
Kcne2 deletion creates a multisystem syndrome predisposing to sudden cardiac death.
Circulation. Cardiovascular genetics.
2014
Academic Article
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Times cited: 37 -
NHE isoform switching and KChIP2 upregulation in aging porcine atria.
PloS one.
2013
Academic Article
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Times cited: 2 -
Rapid genetic algorithm optimization of a mouse computational model: benefits for anthropomorphization of neonatal mouse cardiomyocytes.
Frontiers in physiology.
2012
Academic Article
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Times cited: 28 -
Nonlinear dynamics in cardiology.
Annual review of biomedical engineering.
2012
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Times cited: 48 -
Effects of electrical and structural remodeling on atrial fibrillation maintenance: a simulation study.
PLoS computational biology.
2012
Academic Article
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Times cited: 71 -
Feedback-control induced pattern formation in cardiac myocytes: a mathematical modeling study.
Journal of theoretical biology.
2010
Academic Article
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Times cited: 21 - Off-site control of repolarization alternans in cardiac fibers. Physical review. E, Statistical, nonlinear, and soft matter physics. 2010 Academic Article GET IT
- Pacing-induced spatiotemporal dynamics can be exploited to improve reentry termination efficacy. Physical review. E, Statistical, nonlinear, and soft matter physics. 2009 Academic Article GET IT
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Instability in action potential morphology underlies phase 2 reentry: a mathematical modeling study.
Heart rhythm.
2009
Academic Article
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Times cited: 25 - Resetting and termination of reentry in a loop-and-tail cardiac model. Physical review. E, Statistical, nonlinear, and soft matter physics. 2008 Academic Article GET IT
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A KCNE2 mutation in a patient with cardiac arrhythmia induced by auditory stimuli and serum electrolyte imbalance.
Cardiovascular research.
2007
Academic Article
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Times cited: 33 -
Action potential duration dispersion and alternans in simulated heterogeneous cardiac tissue with a structural barrier.
Biophysical journal.
2006
Academic Article
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Times cited: 23 -
An ionic model for rhythmic activity in small clusters of embryonic chick ventricular cells.
American journal of physiology. Heart and circulatory physiology.
2005
Academic Article
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Times cited: 30 -
Apparent discontinuities in the phase-resetting response of cardiac pacemakers.
Journal of theoretical biology.
2004
Academic Article
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Times cited: 34