selected publications
- FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1. Molecular cell. 2023 Academic Article GET IT
- Decreased Enterobacteriaceae translocation due to gut microbiota remodeling mediates the alleviation of premature aging by a high-fat diet. Aging cell. 2022 Academic Article GET IT
- Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression. Nature communications. 2022 Academic Article GET IT
- Suppression of nuclear GSK3 signaling promotes serine/one-carbon metabolism and confers metabolic vulnerability in lung cancer cells. Science advances. 2022 Academic Article GET IT
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mTORC1 promotes cell growth via m6A-dependent mRNA degradation.
Molecular cell.
2021
Academic Article
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Times cited: 47 -
mTORC1-chaperonin CCT signaling regulates m6A RNA methylation to suppress autophagy.
Proceedings of the National Academy of Sciences of the United States of America.
2021
Academic Article
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Times cited: 44 -
mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-Dependent Foxk1 Phosphorylation.
Molecular cell.
2018
Academic Article
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Times cited: 95 -
Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling.
Cell.
2017
Academic Article
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Times cited: 147 -
Loss of Transcription Factor CREBH Accelerates Diet-Induced Atherosclerosis in Ldlr-/- Mice.
Arteriosclerosis, thrombosis, and vascular biology.
2016
Academic Article
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Times cited: 18 -
CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis.
Scientific reports.
2016
Academic Article
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Times cited: 53 -
IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis.
Molecular and cellular biology.
2015
Academic Article
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Times cited: 22