Selected publications
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Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects.
Proceedings of the National Academy of Sciences of the United States of America.
2019
Academic Article
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Times cited: 11 -
Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis.
Nature Communications.
2018
Academic Article
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Times cited: 18 -
Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress.
DNA Repair.
2018
Academic Article
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Times cited: 3 -
Pre-replicative repair of oxidized bases maintains fidelity in mammalian genomes: The cowcatcher role of NEIL1 DNA glycosylase.
Genes.
2017
Academic Article
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Times cited: 4 -
Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex.
Nucleic Acids Research.
2017
Academic Article
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Times cited: 19 -
8-Oxoguanine DNA glycosylase1–driven DNA repair—A paradoxical role in lung aging.
Mechanisms of Ageing and Development.
2017
Academic Article
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Times cited: 9 -
Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis.
Oncotarget.
2017
Academic Article
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Times cited: 4 -
Chromatin-Bound Oxidized α-Synuclein Causes Strand Breaks in Neuronal Genomes in in vitro Models of Parkinson's Disease.
Journal of Alzheimer's Disease.
2017
Academic Article
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Times cited: 9 -
Chronic oxidative damage together with genome repair deficiency in the neurons is a double whammy for neurodegeneration: Is damage response signaling a potential therapeutic target?.
Mechanisms of Ageing and Development.
2017
Review
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Times cited: 7 -
DNA damage responses in central nervous system and age-associated neurodegeneration.
Mechanisms of Ageing and Development.
2017
Editorial Article
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Times cited: 4 -
Regulation of oxidized base damage repair by chromatin assembly factor 1 subunit A.
Nucleic Acids Research.
2017
Academic Article
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Times cited: 3 -
Depletion of tyrosyl DNA phosphodiesterase 2 activity enhances etoposide-mediated double-strand break formation and cell killing.
DNA Repair.
2016
Academic Article
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Times cited: 12 -
Scaffold attachment factor A (SAF-A) and Ku temporally regulate repair of radiation-induced clustered genome lesions.
Oncotarget.
2016
Academic Article
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Times cited: 5 -
Increased human AP endonuclease 1 level confers protection against the paternal age effect in mice.
Mutation Research - DNA Repair.
2015
Academic Article
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Times cited: 2 -
The C-terminal domain (CTD) of human DNA glycosylase NEIL1 is required for forming BERosome repair complex with DNA replication proteins at the replicating genome: Dominant negative function of the CTD.
Journal of Biological Chemistry.
2015
Academic Article
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Times cited: 21 -
New paradigms in the repair of oxidative damage in human genome: Mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins.
Cellular and Molecular Life Sciences.
2015
Review
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Times cited: 21 - A tribute in memory of Richard B. (Dick) Setlow (1921-2015). DNA Repair. 2015 In Process GET IT
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Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: Implications for the regulation of mitochondrial function.
Nucleic Acids Research.
2014
Academic Article
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Times cited: 36 -
New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases.
Biomolecules.
2014
Review
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Times cited: 18 -
Innate inflammation induced by the 8-oxoguanine DNA glycosylase-1-KRAS-NF-κB pathway.
Journal of Immunology.
2014
Academic Article
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Times cited: 53 -
Oxidative stress: An essential factor in the pathogenesis of gastrointestinal mucosal diseases.
Physiological Reviews.
2014
Review
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Times cited: 543 -
Systems approaches to modeling chronic mucosal inflammation.
BioMed Research International.
2013
Academic Article
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Times cited: 26 -
Deficiency in Repair of the Mitochondrial Genome Sensitizes Proliferating Myoblasts to Oxidative Damage.
PLoS ONE.
2013
Academic Article
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Times cited: 27 -
Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins.
Proceedings of the National Academy of Sciences of the United States of America.
2013
Academic Article
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Times cited: 53 -
Dual Regulatory Roles of Human AP-Endonuclease (APE1/Ref-1) in CDKN1A/p21 Expression.
PLoS ONE.
2013
Academic Article
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Times cited: 14 -
The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions.
Journal of Molecular Biology.
2013
Academic Article
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Times cited: 30 -
Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes.
Journal of Biological Chemistry.
2013
Academic Article
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Times cited: 47 -
The interaction between polynucleotide kinase phosphatase and the DNA repair protein XRCC1 is critical for repair of DNA alkylation damage and stable association at DNA damage sites.
Journal of Biological Chemistry.
2012
Academic Article
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Times cited: 19 -
Enhancement of NEIL1 protein-initiated oxidized DNA base excision repair by heterogeneous nuclear ribonucleoprotein U (hnRNP-U) via direct interaction.
Journal of Biological Chemistry.
2012
Academic Article
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Times cited: 29 -
Oxidized base damage and single-strand break repair in mammalian genomes: Role of disordered regions and posttranslational modifications in early enzymes.
Progress in Molecular Biology and Translational Science.
2012
Review
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Times cited: 36 -
Activation of Ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine.
Journal of Biological Chemistry.
2012
Academic Article
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Times cited: 76 -
Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interaction.
Journal of Neuroscience Research.
2012
Academic Article
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Times cited: 25 -
Regulation of mouse-renin gene by apurinic/apyrimidinic-endonuclease 1 (APE1/Ref-1) via recruitment of histone deacetylase 1 corepressor complex.
Journal of Hypertension.
2012
Academic Article
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Times cited: 11 -
Oxidative genome damage and its repair: Implications in aging and neurodegenerative diseases.
Mechanisms of Ageing and Development.
2012
Review
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Times cited: 86 -
Human DNA glycosylase NEIL1's interactions with downstream repair proteins is critical for efficient repair of oxidized DNA base damage and enhanced cell survival.
Biomolecules.
2012
Academic Article
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Times cited: 19 -
Does evening sun increase the risk of skin cancer?.
Proceedings of the National Academy of Sciences of the United States of America.
2011
Comment
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Times cited: 5 -
Impaired integrity of DNA after recovery from inflammation causes persistent dysfunction of colonic smooth muscle.
Gastroenterology.
2011
Academic Article
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Times cited: 16 -
Apoptosis induced by persistent single-strand breaks in mitochondrial genome: Critical role of EXOG (5′-exo/endonuclease) in their repair.
Journal of Biological Chemistry.
2011
Academic Article
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Times cited: 97 -
Fen1 mutations that specifically disrupt its interaction with PCNA cause aneuploidy-associated cancer.
Cell Research.
2011
Academic Article
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Times cited: 24 -
Oxidative genome damage and its repair in neurodegenerative diseases: Function of transition metals as a double-edged sword.
Journal of Alzheimer's Disease.
2011
Review
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Times cited: 41 -
Obesity and hepatosteatosis in mice with enhanced oxidative DNA damage processing in mitochondria.
American Journal of Pathology.
2011
Academic Article
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Times cited: 15 -
Preferential repair of oxidized base damage in the transcribed genes of mammalian cells.
Journal of Biological Chemistry.
2011
Academic Article
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Times cited: 84 -
Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1.
Oncogene.
2011
Academic Article
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Times cited: 72 -
Functions of disordered regions in mammalian early base excision repair proteins.
Cellular and Molecular Life Sciences.
2010
Review
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Times cited: 42 -
Specific inhibition of NEIL-initiated repair of oxidized base damage in human genome by copper and iron: Potential etiological linkage to neurodegenerative diseases.
Journal of Biological Chemistry.
2010
Academic Article
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Times cited: 37 -
RPA physically interacts with the human DNA glycosylase NEIL1 to regulate excision of oxidative DNA base damage in primer-template structures.
DNA Repair.
2010
Academic Article
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Times cited: 39 -
Age- and tissue-specific changes in mitochondrial and nuclear DNA base excision repair activity in mice: Susceptibility of skeletal muscles to oxidative injury.
Mechanisms of Ageing and Development.
2010
Academic Article
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Times cited: 44 -
DNA base excision repair: A recipe for survival.
2009
Chapter
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Times cited: 2 -
p53-mediated down-regulation of the human DNA repair gene O 6-methylguanine-DNA methyltransferase (MGMT) via interaction with Sp1 transcription factor.
Anticancer Research.
2009
Academic Article
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Times cited: 64 -
Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA.
Nucleic Acids Research.
2009
Academic Article
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Times cited: 82 -
Acetylation of Apurinic/Apyrimidinic Endonuclease-1 Regulates Helicobacter pylori-Mediated Gastric Epithelial Cell Apoptosis.
Gastroenterology.
2009
Academic Article
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Times cited: 36 -
Tumor necrosis factor (TNF)-α-induced IL-8 expression in gastric epithelial cells: Role of reactive oxygen species and AP endonuclease-1/redox factor (Ref)-1.
Cytokine.
2009
Academic Article
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Times cited: 21 -
Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein.
Antioxidants and Redox Signaling.
2009
Review
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Times cited: 153 -
Genome-Wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells.
Proteomics.
2009
Academic Article
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Times cited: 65 -
Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1.
Molecular and Cellular Biology.
2008
Academic Article
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Times cited: 85 -
Physical and functional interaction between human oxidized base-specific DNA glycosylase NEIL1 and flap endonuclease.
Journal of Biological Chemistry.
2008
Academic Article
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Times cited: 68 -
Long patch base excision repair in mammalian mitochondrial genomes.
Journal of Biological Chemistry.
2008
Academic Article
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Times cited: 107 -
Mutator phenotype of mammalian cells due to deficiency of NEIL1 DNA glycosylase, an oxidized base-specific repair enzyme.
DNA Repair.
2008
Academic Article
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Times cited: 22 -
Unusual Role of a Cysteine Residue in Substrate Binding and Activity of Human AP-Endonuclease 1.
Journal of Molecular Biology.
2008
Academic Article
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Times cited: 24 -
Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage.
Nucleic Acids Research.
2008
Academic Article
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Times cited: 80 -
Base-pairing properties of the oxidized cytosine derivative, 5-hydroxy uracil.
Biochemical and Biophysical Research Communications.
2008
Academic Article
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Times cited: 34 -
Interaction of the human DNA glycosylase NEIL1 with proliferating cell nuclear antigen: The potential for replication-associated repair of oxidized bases in mammalian genomes.
Journal of Biological Chemistry.
2008
Academic Article
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Times cited: 108 - A special issue on DNA damage responses and genome maintenance. Cell Research. 2008 Editorial Article GET IT
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APE1/Ref-1 regulates PTEN expression mediated by Egr-1.
Free Radical Research.
2008
Academic Article
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Times cited: 43 -
Discrimination of lesion removal of N-methylpurine-DNA glycosylase revealed by a potent neutralizing monoclonal antibody.
DNA Repair.
2008
Academic Article
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Times cited: 7 -
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells.
Cell Research.
2008
Review
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Times cited: 383 -
The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1.
Journal of Biological Chemistry.
2007
Academic Article
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Times cited: 81 -
MGMT: A personal perspective.
DNA Repair.
2007
Review
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Times cited: 32 -
Intracellular trafficking and regulation of mammalian AP-endonuclease 1 (APE1), an essential DNA repair protein.
DNA Repair.
2007
Academic Article
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Times cited: 74 -
The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates NEIL1 glycosylase.
Nucleic Acids Research.
2007
Academic Article
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Times cited: 55 -
NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells.
DNA Repair.
2006
Academic Article
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Times cited: 87 -
Interleukin-8 induction by Helicobacter pylori in gastric epithelial cells is dependent on apurinic/apyrimidinic endonuclease-1/redox factor-1.
Journal of Immunology.
2006
Academic Article
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Times cited: 28 -
Localization of superoxide anion production to mitochondrial electron transport chain in 3-NPA-treated cells.
Mitochondrion.
2006
Academic Article
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Times cited: 35 -
Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells.
Nucleic Acids Research.
2006
Academic Article
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Times cited: 106 -
Purification and Characterization of NEIL1 and NEIL2, Members of a Distinct Family of Mammalian DNA Glycosylases for Repair of Oxidized Bases.
Methods in Enzymology.
2006
Article
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Times cited: 20 - LVMH Recherche Symposium on mitochondria October 6th, 2005 Paris. Bioscience Reports. 2006 Academic Article GET IT
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Acetylation of human 8-oxoguanine-DNA glycosylase by p300 and its role in 8-oxoguanine repair in vivo.
Molecular and Cellular Biology.
2006
Academic Article
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Times cited: 117 -
Induction of the human oxidized base-specific DNA glycosylase NEIL1 by reactive oxygen species.
Journal of Biological Chemistry.
2005
Academic Article
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Times cited: 57 -
Effect of aging on intracellular distribution of abasic (AP) endonuclease 1 in the mouse liver.
Mechanisms of Ageing and Development.
2005
Academic Article
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Times cited: 29 -
Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1).
Nucleic Acids Research.
2005
Academic Article
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Times cited: 60 -
ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation.
Journal of Clinical Investigation.
2005
Academic Article
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Times cited: 258 -
Two essential but distinct functions of the mammalian abasic endonuclease.
Proceedings of the National Academy of Sciences of the United States of America.
2005
Academic Article
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Times cited: 169 -
Identification of a zinc finger domain in the human NEIL2 (Nei-like-2) protein.
Journal of Biological Chemistry.
2004
Academic Article
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Times cited: 27 -
Age-dependent modulation of DNA repair enzymes by covalent modification and subcellular distribution.
Mechanisms of Ageing and Development.
2004
Academic Article
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Times cited: 51 -
Stimulation of DNA glycosylase activity of OGG1 by NEIL1: Functional collaboration between two human DNA glycosylases.
Biochemistry.
2004
Academic Article
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Times cited: 55 -
Helicobacter pylori and H
2 O2 increase AP endonuclease-1/redox factor-1 expression in human gastric epithelial cells. Gastroenterology. 2004 Academic Article GET IT
Times cited: 71 -
Acetylation of the human DNA glycosylase NEIL2 and inhibition of its activity.
Nucleic Acids Research.
2004
Academic Article
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Times cited: 61 -
AP endonuclease-independent DNA base excision repair in human cells.
Molecular Cell.
2004
Academic Article
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Times cited: 327 -
The major role of human AP-endonuclease homolog Apn2 in repair of abasic sites in Schizosaccharomyces pombe.
Nucleic Acids Research.
2004
Academic Article
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Times cited: 31 -
Acetylation of Human AP-Endonuclease 1, A Critical Enzyme in DNA Repair and Transcription Regulation.
Methods in Enzymology.
2003
Article
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Times cited: 13 -
Repair of Oxidized Bases in DNA Bubble Structures by Human DNA Glycosylases NEIL1 and NEIL2.
Journal of Biological Chemistry.
2003
Academic Article
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Times cited: 249 -
Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene.
EMBO Journal.
2003
Academic Article
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Times cited: 139 -
Mammalian DNA base excision repair proteins: Their interactions and role in repair of oxidative DNA damage.
Toxicology.
2003
Article
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Times cited: 161 -
Reduced DNA double strand breaks in chlorambucil resistant cells are related to high DNA-PKcs activity and low oxidative stress.
Toxicology.
2003
Academic Article
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Times cited: 52 -
Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases.
Proceedings of the National Academy of Sciences of the United States of America.
2003
Academic Article
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Times cited: 93 -
CpG methylation-dependent repression of the human O6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration.
Carcinogenesis.
2003
Academic Article
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Times cited: 50 -
The discovery of a new family of mammalian enzymes for repair of oxidatively damaged DNA, and its physiological implications.
Carcinogenesis.
2003
Academic Article
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Times cited: 57 -
Solution structure of a DNA duplex containing 8-hydroxy-2′-deoxyguanosine opposite deoxyguanosine.
Journal of Molecular Biology.
2003
Academic Article
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Times cited: 19 -
Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions.
Journal of Biological Chemistry.
2002
Academic Article
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Times cited: 245 -
Binding of specific DNA base-pair mismatches by N-methylpurine-DNA glycosylase and its implication in initial damage recognition.
Journal of Molecular Biology.
2002
Academic Article
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Times cited: 22 -
Choreography of oxidative damage repair in mammalian genomes.
Free Radical Biology and Medicine.
2002
Article
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Times cited: 114 -
Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA.
Proceedings of the National Academy of Sciences of the United States of America.
2002
Academic Article
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Times cited: 376 -
Human AP-endonuclease 1 and hnRNP-L interact with a nCaRE-like repressor element in the AP-endonuclease 1 promoter.
Nucleic Acids Research.
2002
Academic Article
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Times cited: 62 -
Multifaceted resistance of gliomas to temozolomide.
Clinical Cancer Research.
2002
Academic Article
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Times cited: 92 - Preface. Progress in nucleic acid research and molecular biology. 2001 Editorial Article
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Session 4 DNA glycosylases: Specificity and mechanisms.
Progress in nucleic acid research and molecular biology.
2001
Review
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Times cited: 15 -
Oxidative DNA damage and 8-hydroxy-2-deoxyguanosine DNA glycosylase/apurinic lyase in human breast cancer.
Molecular Carcinogenesis.
2001
Academic Article
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Times cited: 59 -
Repair of hydantoins, one electron oxidation product of 8-oxoguanine, by DNA glycosylases of Escherichia coli.
Nucleic Acids Research.
2001
Academic Article
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Times cited: 90 -
Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: Potential coordination of the initial steps in base excision repair.
Nucleic Acids Research.
2001
Academic Article
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Times cited: 297 -
Multiple DNA glycosylases for repair of 8-oxoguanine and their potential in Vivo functions.
Progress in nucleic acid research and molecular biology.
2001
Article
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Times cited: 102 -
Spatial expression of a DNA repair gene, N-methylpurine-DNA glycosylase (MPG) during development in mice.
Anticancer Research.
2000
Academic Article
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Times cited: 16 -
Regulation of the human O6-methylguanine-DNA methyltransferase gene by transcriptional coactivators cAMP response element-binding protein-binding protein and p300.
Journal of Biological Chemistry.
2000
Academic Article
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Times cited: 47 -
Characterization of a novel 8-oxoguanine-DNA glycosylase activity in Escherichia coli and identification of the enzyme as endonuclease VIII.
Journal of Biological Chemistry.
2000
Academic Article
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Times cited: 83 -
Requirement for human AP endonuclease 1 for repair of 3'-blocking damage at DNA single-strand breaks induced by reactive oxygen species.
Carcinogenesis.
2000
Academic Article
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Times cited: 160 -
Deficiency of N-methylpurine-DNA-glycosylase expression in nonparenchymal cells, the target cell for vinyl chloride and vinyl fluoride.
Mutation Research - DNA Repair.
2000
Academic Article
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Times cited: 15 -
Mitochondrial DNA damage and a hypoxic response are induced by CoCl
2 in rat neuronal PC12 cells. Nucleic Acids Research. 2000 Academic Article GET IT
Times cited: 131 -
Mutation of a unique aspartate residue abolishes the catalytic activity but not substrate binding of the mouse N-methylpurine-DNA glycosylase (MPG).
Journal of Biological Chemistry.
2000
Academic Article
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Times cited: 7 -
DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination.
Nature.
2000
Academic Article
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Times cited: 479 -
Acquired alkylating drug resistance of a human ovarian carcinoma cell line is unaffected by altered levels of pro- and anti-apoptotic proteins.
Oncogene.
2000
Academic Article
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Times cited: 23 -
Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase μ.
Biochemical Pharmacology.
1999
Academic Article
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Times cited: 41 -
Intragenic suppression of an active site mutation in the human apurinic/apyrimidinic endonuclease.
Journal of Molecular Biology.
1999
Academic Article
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Times cited: 42 -
Activation of human O6-methylguanine-DNA methyltransferase gene by glucocorticoid hormone.
Oncogene.
1999
Academic Article
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Times cited: 61 -
APE/Ref-1 responses to ischemia in rat brain.
NeuroReport.
1998
Academic Article
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Times cited: 35 -
APE/Ref-1 responses to oxidative stress in aged rats.
Journal of Neuroscience Research.
1998
Academic Article
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Times cited: 55 -
The presence of two distinct 8-oxoguanine repair enzymes in human cells: Their potential complementary roles in preventing mutation.
Nucleic Acids Research.
1998
Academic Article
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Times cited: 155 -
Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites.
Genes and Development.
1998
Academic Article
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Times cited: 166 -
Regulation of expression of the DNA repair gene-O6-methylguanine-DNA methyltransferase via protein kinase C-mediated signaling.
Cancer Research.
1998
Academic Article
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Times cited: 79 -
Purification and characterization of human NTH1, a homolog of Escherichia coli endonuclease III.
Journal of Biological Chemistry.
1998
Academic Article
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Times cited: 204 -
Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals.
Proceedings of the National Academy of Sciences of the United States of America.
1998
Academic Article
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Times cited: 357 -
Deletion analysis of human AP-endonuclease: Minimum sequence required for the endonuclease activity.
Carcinogenesis.
1998
Academic Article
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Times cited: 71 -
Reversible folding of Ada protein (O6-methylguanine-DNA methyltransferase) of Escherichia coli.
Biochemistry.
1998
Academic Article
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Times cited: 3 -
Specific interaction of wild-type and truncated mouse N-methylpurine- DNA glycosylase with ethenoadenine-containing DNA.
Biochemistry.
1998
Academic Article
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Times cited: 51 -
Molecular cloning and characterization of the promoter of the human N-methylpurine-DNA glycosylase (MPG) gene.
Carcinogenesis.
1997
Academic Article
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Times cited: 8 -
Complexities of DNA Base Excision Repair in Mammalian Cells.
Molecules and Cells.
1997
Review
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Times cited: 122 -
Amplification of the DNA repair gene O6-methylguanine-DNA methyltransferase associated with resistance to alkylating drugs in a mammalian cell line.
Journal of Biological Chemistry.
1997
Academic Article
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Times cited: 20 -
Specific recognition of O6-methylguanine in DNA by active site mutants of human O6-methylguanine-DNA methyltransferase.
Biochemistry.
1997
Academic Article
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Times cited: 52 -
Quantitative reverse transcriptase polymerase chain reaction for measuring the N-methylpurine-DNA glycosylase mRNA level in rodent cells.
Analytical Biochemistry.
1997
Academic Article
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Times cited: 9 -
Mutations of O6-methylguanine-DNA methyltransferase gene in esophageal cancer tissue from Northern China.
International Journal of Cancer.
1997
Academic Article
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Times cited: 38 - Adaptive response in human cells: Induction of AP-Endonuclease by sublethal levels of reactive oxygen-species. FASEB Journal. 1996 Academic Article
-
Cloning and characterization of the mouse alpha globin cluster and a new hypervariable marker.
Mammalian Genome.
1996
Academic Article
GET IT
Times cited: 5 -
Induction of genes involved in dna alkylation repair in rat hepatoma cells.
FASEB Journal.
1996
Academic Article
Times cited: 1 - Minimum size of active human O6-methylguanine-dna methyltransference (MGMT); substrate binding parallels mgmt activity. FASEB Journal. 1996 Academic Article
- Promoter function of the human ap-endonuclease. FASEB Journal. 1996 Academic Article
- The domains of mammalian base excision repair enzyme w-methylpurine-dna glycosylase: Interaction, conformational change and role in dna-binding and damage recognition. FASEB Journal. 1996 Academic Article
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Negative regulation of the major human AP-endonuclease, a multifunctional protein.
Biochemistry.
1996
Academic Article
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Times cited: 68 -
Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes.
Carcinogenesis.
1996
Academic Article
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Times cited: 105 -
The domains of mammalian base excision repair enzyme N-methylpurine-DNA glycosylase. Interaction, conformational change, and role in DNA binding and damage recognition.
Journal of Biological Chemistry.
1996
Academic Article
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Times cited: 20 -
Distinct substrate preference of human and mouse N-methylpurine-DNA glycosylases.
Carcinogenesis.
1996
Academic Article
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Times cited: 39 -
DNA repair and its regulatory pathways in cancer pharmacology.
Medecine sciences : M/S.
1996
Academic Article
Times cited: 3 -
A comparative study of the biochemical properties of human and mouse recombinant O6-methylguanine-DNA methyltransferases.
Carcinogenesis.
1995
Academic Article
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Times cited: 15 -
Enhanced host cell reactivation capacity and expression of DNA repair genes in human breast cancer cells resistant to bi-functional alkylating agents.
Mutation Research - DNA Repair.
1995
Academic Article
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Times cited: 32 -
Structural Organization of the Mouse DNA Repair Gene, N-Methylpurine-DNA Glycosylase.
DNA and Cell Biology.
1995
Academic Article
GET IT
Times cited: 21 -
Purification and biochemical characterization of recombinant N-methylpurine-DNA glycosylase of the mouse.
Biochemistry.
1994
Academic Article
GET IT
Times cited: 48 -
Cloning of a marsupial DNA photolyase gene and the lack of related nucleotide sequences in placental mammals.
Nucleic Acids Research.
1994
Academic Article
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Times cited: 73 -
1,N6-ethenoadenine is preferred over 3-methyladenine as substrate by a cloned human N-methylpurine-DNA glycosylase (3-methyladenine-DNA glycosylase).
Biochemistry.
1994
Academic Article
GET IT
Times cited: 92 -
Repair of 8-hydroxyguanine in DNA by mammalian N-methylpurine-DNA glycosylase.
Proceedings of the National Academy of Sciences of the United States of America.
1993
Academic Article
GET IT
Times cited: 134 -
Brain and liver targeted overexpression of O6-methylguanine DNA methyltransferase in transgenic mice.
Carcinogenesis.
1993
Academic Article
GET IT
Times cited: 15 -
Regulation of repair of alkylation damage in mammalian genomes.
Progress in nucleic acid research and molecular biology.
1993
Review
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Times cited: 181 -
Cytosine methylation and suppression of O6-methylguanine-DNA methyltransferase expression in human rhabdomyosarcoma cell lines and xenografts.
Oncology Research.
1992
Academic Article
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Times cited: 34 -
Overexpression of human DNA repair protein N-methylpurine-DNA glycosylase results in the increased removal of N-methylpurines in DNA without a concomitant increase in resistance to alkylating agents in chinese hamster ovary cells.
Carcinogenesis.
1992
Academic Article
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Times cited: 65 -
Characterization of cDNA encoding mouse DNA repair protein O6- methylguanine-DNA methyltransferase and high-level expression of the wild- type and mutant proteins in Escherichia coli.
Biochemistry.
1992
Academic Article
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Times cited: 26 -
Chromosomal localization of human O6-methylguanine-DNA methyltransferase (MGMT) gene by in situ hybridization.
Mutagenesis.
1992
Academic Article
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Times cited: 45 -
Correlation between DNA methylation and expression of O6-methylguanine-DNA methyltransferase gene in cultured human tumor cells.
Mutation Research - DNA Repair.
1992
Academic Article
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Times cited: 42 -
Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase.
Journal of Biological Chemistry.
1991
Academic Article
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Times cited: 129 -
Inducibility of the DNA repair gene encoding O6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments.
Molecular and Cellular Biology.
1991
Academic Article
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Times cited: 125 -
Characterization of the promoter region of the human O6-methylguanine-DNA methyltransferase gene.
Nucleic Acids Research.
1991
Academic Article
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Times cited: 129 -
Mutations induced by ionizing radiation in a plasmid replicated in human cells. I. Similar, nonrandom distribution of mutations in unirradiated and X-irradiated DNA.
Radiation Research.
1991
Academic Article
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Times cited: 36 -
Mutations induced by ionizing radiation in a plasmid replicated in human cells. II. Sequence analysis of α-particle-induced point mutations.
Radiation Research.
1991
Academic Article
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Times cited: 25 -
Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in chinese hamster cells: The role of MGMT in protection against the genotoxic effects of alkylating agents.
Carcinogenesis.
1991
Academic Article
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Times cited: 235 -
Expression of O6-methylguanine-DNA methyltransferase in malignant human glioma cell lines.
Carcinogenesis.
1991
Academic Article
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Times cited: 39 -
The origin of O6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells transfected with human DNA.
Mutation Research - DNA Repair.
1991
Academic Article
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Times cited: 4 -
Structural and immunological comparison of indigenous human O6-methylguanine-DNA methyltransferase with that encoded by a cloned cDNA.
Journal of Biological Chemistry.
1991
Academic Article
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Times cited: 22 -
The origin of O6-methylguanine-DNA methyltransferase in Chinese hamster overy cells transfected with human DNA.
Mutation Research - DNA Repair.
1991
Academic Article
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Times cited: 14 -
The role of O6-alkylguanine in cell killing and mutagenesis in chinese hamster ovary cells.
Carcinogenesis.
1991
Academic Article
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Times cited: 38 -
Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine.
Proceedings of the National Academy of Sciences of the United States of America.
1990
Academic Article
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Times cited: 261 -
N‐methyl‐N‐nitrosourea‐lnduced mutations in a shuttle plasmid replicated in human cells.
Molecular Carcinogenesis.
1990
Academic Article
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Times cited: 18 -
Physicochemical studies of human O6‐methylguanine‐DNA methyltransferase.
European Journal of Biochemistry.
1990
Academic Article
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Times cited: 35 -
Age-dependent modulation of tissue-specific repair activity for 3-methyladenine and O6-methylguanine in DNA in inbred mice.
Mechanisms of Ageing and Development.
1989
Academic Article
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Times cited: 44 -
O6-Alkylguanine-DNA alkyltransferase and sensitivity to procarbazine in human brain-tumor xenografts.
Journal of Neurosurgery.
1989
Academic Article
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Times cited: 137 -
Site-directed mutation of the Escherichia coli ada gene: Effects of substitution of methyl acceptor cysteine-321 by histidine in Ada protein.
Journal of Bacteriology.
1989
Academic Article
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Times cited: 13 -
Mutagenic potential of modified DNA precursors in vivo: Fate of O6-methyldeoxyguanosine triphosphate in Chinese hamster ovary cells.
Indian Journal of Biochemistry and Biophysics.
1988
Academic Article
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Times cited: 5 -
Rapid, large-scale purification and characterization of 'ada protein' (06 methylguanine-DNA methyltransferase) of E.coli.
Nucleic Acids Research.
1988
Academic Article
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Times cited: 22 -
High-level expression of the cloned ada gene of Escherichia coli by deletion of its regulatory sequence.
Gene.
1988
Academic Article
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Times cited: 5 -
Effect of polyvalent metal ions on the reactivity of human o-methylguanine-dna methyltransferase.
Carcinogenesis.
1988
Academic Article
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Times cited: 22 -
Tissue-specific variation in repair activity for 3-methyladenine in DNA in two stocks of mice.
Mutation Research - DNA Repair.
1988
Academic Article
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Times cited: 19 -
Role of carcinogen-modified deoxynucleotide precursors in mutagenesis.
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis.
1988
Academic Article
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Times cited: 14 -
Function of Lys-166 of Rhodospirillum rubrum ribulosebisphosphate carboxylase/oxygenase as examined by site-directed mutagenesis.
Journal of Biological Chemistry.
1987
Academic Article
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Times cited: 39 -
Purification and some properties of human DNA-O6-methylguanine methyltransferase.
Journal of Biosciences.
1987
Academic Article
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Times cited: 20 - Site-directed mutagenesis to determine essential residues of ribulose-bisphosphate carboxylase of Rhodospirillum rubrum. Journal of Biosciences. 1987 Academic Article GET IT
-
Controversies in basic science: Do carcinogen-modified deoxynucleotide precursors contribute to cellular mutagenesis?.
Cancer Investigation.
1987
Academic Article
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Times cited: 8 -
Nonessentiality of histidine 291 of Rhodospirillum rubrum ribulose-bisphosphate carboxylase/oxygenase as determined by site-directed mutagenesis.
Journal of Biological Chemistry.
1986
Academic Article
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Times cited: 36 -
Cell cycle-dependent modulation of o-methylguanine-dna methyltransferse in c3h/10t1/2 cells.
Carcinogenesis.
1986
Academic Article
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Times cited: 25 -
Proteins tightly associated with the termini of replicative form DNA of Kilham rat virus, an autonomous parvovirus.
Proceedings of the National Academy of Sciences of the United States of America.
1985
Academic Article
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Times cited: 7 -
Structure of the capsid of Kilham rat virus from small-angle neutron scattering.
Biochemistry.
1984
Academic Article
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Times cited: 4 -
Kinetics of incorporation of O6-methyldeoxyguanosine monophosphate during in vitro DNA synthesis.
Biochemistry.
1984
Academic Article
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Times cited: 28 -
Lack of induction of o-methylguanine-dna methyltransferase in mammalian cells treated with n-methyl-n' -nitro-n-nitrosoguanidine.
Carcinogenesis.
1984
Academic Article
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Times cited: 51 -
Autonomous parvovirus LuIII encapsidates equal amounts of plus and minus DNA strands.
Journal of Virology.
1984
Academic Article
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Times cited: 16 -
Base-pairing properties of O6-methylguanine in template DNA during in vitro DNA replication.
Journal of Biological Chemistry.
1984
Academic Article
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Times cited: 130 - Characterization of proteins tightly associated with replicative form DNA of Kilham rat virus. Federation Proceedings. 1984 Academic Article
-
O6-Methylguanine-DNA methyltransferase in human cells.
Mutation Research DNA Repair Reports.
1984
Academic Article
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Times cited: 75 -
Distribution of restriction enzyme sites in the bovine parvovirus genome and comparison to other autonomous parvoviruses.
Journal of General Virology.
1983
Academic Article
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Times cited: 2 -
Repair of O6-methylguanine in DNA by demethylation is lacking in Mer- human tumor cell strains.
Carcinogenesis.
1983
Academic Article
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Times cited: 153 -
Replication and Demethylation of O
6 -Methylguanine in DNA. Progress in nucleic acid research and molecular biology. 1983 Academic Article GET IT
Times cited: 4 -
Electron microscopic comparison of the sequences of single-stranded genomes of mammalian parvoviruses by heteroduplex mapping.
Journal of Molecular Biology.
1983
Academic Article
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Times cited: 4 -
Purification and properties of O6-methylguanine-DNA transmethylase from rat liver.
Journal of Biological Chemistry.
1983
Academic Article
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Times cited: 217 -
Quantitation of O6-methylguanine-DNA methyltransferase in HeLa cells.
Mutation Research Letters.
1983
Academic Article
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Times cited: 52 -
Comparative physicochemical and biological properties of two strains of Kilham rat virus, a non-defective parvovirus.
Journal of General Virology.
1982
Academic Article
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Times cited: 8 -
Mutagenesis of bacteriophage T7 in vitro by incorporation of O6-methylguanine during DNA synthesis.
Proceedings of the National Academy of Sciences of the United States of America.
1982
Academic Article
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Times cited: 47 -
O6-Methylguanine-DNA methyltransferase in wild-type and ada mutants of Escherichia coli.
Journal of Bacteriology.
1982
Academic Article
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Times cited: 43 -
Calibration of denaturing agarose gels for molecular weight estimation of DNA: Size determination of the single‐stranded genomes of parvoviruses.
Electrophoresis.
1982
Academic Article
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Times cited: 2 -
Restriction map of the single-stranded DNA genome of Kilham rat virus strain 171, a nondefective parvovirus.
Journal of Virology.
1981
Academic Article
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Times cited: 3 -
DNA replication in viruses.
Annual Review of Genetics.
1980
Review
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Times cited: 7 -
Demethylation of O6-methylguanine synthetic DNA polymer by an inducible activity in Escherichia coli.
Biochemical and Biophysical Research Communications.
1980
Academic Article
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Times cited: 133 -
Comparison of specific binding sites for Escherichia coli RNA polymerase with naturally occurring hairpin regions in single-stranded DNA of coliphage M13.
Journal of Biological Chemistry.
1978
Academic Article
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Times cited: 2 -
Structure of nascent replicative form DNA of coliphage M13.
Proceedings of the National Academy of Sciences of the United States of America.
1978
Academic Article
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Times cited: 1 -
Isolation and characterization of naturally occurring hairpin structures in single-stranded DNA of coliphage M13.
Biochemical and Biophysical Research Communications.
1977
Academic Article
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Times cited: 1 -
Base-unpaired regions in supercoiled replicative form DNA of coliphage M13.
Journal of Biological Chemistry.
1977
Academic Article
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Times cited: 25 -
Electron microscopic studies of bacteriophage M13 DNA replication.
Journal of Virology.
1977
Academic Article
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Times cited: 7 -
The role of DNA polymerase I-associated 5′-exonuclease in replication of coliphage M13 replicative-form DNA.
Biochemical and Biophysical Research Communications.
1977
Academic Article
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Times cited: 1 -
The Role of Escherichia coli dnaA Gene and Its Integrative Suppression in M 13 Coliphage DNA Synthesis.
European Journal of Biochemistry.
1976
Academic Article
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Times cited: 5 -
Strand separation of DNA induced by ultraviolet irradiation in vitro.
BBA Section Nucleic Acids And Protein Synthesis.
1974
Academic Article
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Times cited: 14 - Transcriptional control of M13 phage DNA replication. Basic life sciences. 1974 Academic Article GET IT
-
Role of dna genes of Escherichia coli in M13 phage replication.
Virology.
1973
Academic Article
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Times cited: 7 -
Inhibition of M13 phage synthesis by rifampicin in some rifampicin-resistant Escherichia coli mutants.
Virology.
1972
Academic Article
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Times cited: 1 -
Susceptibility of E. coli K-12 to actinomycin D after Infection with phage M13.
Nature.
1970
Academic Article
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Times cited: 4 -
Increased fragility of Escherichia coli after infection with bacteriophage M13.
Journal of Virology.
1970
Academic Article
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Times cited: 12 -
Denaturation of DNA after X-irradiation in vitro.
Biochemical and Biophysical Research Communications.
1970
Academic Article
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Times cited: 6 -
Enzymic synthesis of deoxyribonucleic acid. XXII. Replication of a circular single-stranded DNA template by DNA polymerase of Escherichia coli.
Journal of Molecular Biology.
1967
Academic Article
Times cited: 6 -
Biophysical properties of RNA from turnip yellow mosaic virus.
Journal of Molecular Biology.
1965
Academic Article
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Times cited: 18 -
Interaction of polyamines with turnip yellow mosaic virus RNA.
Biochemical and Biophysical Research Communications.
1963
Academic Article
Times cited: 10 -
Lecithin-splitting enzyme of Vibrio E1 Tor.
Nature.
1961
Academic Article
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Times cited: 1