Richard A Friedman   Professor of Clinical Psychiatry

Phone
  • +1 212 746 5775

 

 

Dr. Friedman is Professor of Clinical Psychiatry at Weill Cornell Medical College and Director of the Psychopharmacology Clinic in the Department of Psychiatry. Dr. Friedman has a particular interest and expertise in the psychopharmacology and neurobiology of mood disorders, and in particular, treatment-resistant depression.

Recently, he has done research in the military’s use of various psychotropic medications in active duty troops during the Iraq and Afghanistan wars and is now extending this research to the veteran population. 

Dr. Friedman is actively involved in teaching and training psychiatric residents and is the Director of Student Mental Health at Weill Cornell Medical College. He has also done research in depressive disorders, including studies of new medications for depression and large collaborative study of the genetics and neurobiology of bipolar disorder. 

Dr. Friedman has authored publications in the New England Journal of Medicine, the Journal of the American Medical Association and the American Journal of Psychiatry, among others. He is also a contributing Op-Ed writer at the New York Times  where he writes on mental health, addiction, human behavior, and neuroscience.

Treatment of Chronic Depression

The current aims of Dr. Friedman's research are:

  1. To evaluate the efficacy of various antidepressant medications in the treatment of chronic depression.
  2. To study the effectiveness of long-term maintenance antidepressant treatment in chronic depression.
  3. To study the neurobiology of chronic depression.
  4. To study the social and occupational impairments of chronic depression.

Dr. Friedman is currently conducting the following clinical studies:

  • A double blind comparison of sertraline versus imipramine for "double depression" (i.e., dysthymia with major depression) and chronic major depression for both short and long-term treatment.

  • A double blind long-term study of desipramine versus placebo for dysthymia and other forms of chronic depression.

  • A tryptophan depletion paradigm, which acutely lowers brain serotonin levels, to study the role of serotonin in chronic depression.

Future plans include a study to simultaneously examine brain activity with MRI, behavior, and serotonin functions in patients with chronic depression.

Publications

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Selected publications

  • Antidepressants' black-box warning--10 years later.  The New England journal of medicine2014 Academic Article GET IT
    Times cited: 18
  • Antidepressants' black-box warning--10 years laterThe New England journal of medicine2014 Academic Article GET IT
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  • How should the psychiatric profession respond to the recent mass killings?The American journal of psychiatry2013 Editorial Article GET IT
    Times cited: 4
  • Grief, depression, and the DSM-5.  The New England journal of medicine2012 Academic Article GET IT
    Times cited: 34
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  • Role of physicians and mental health professionals in discussions of public figuresJAMA : the journal of the American Medical Association2008 Academic Article GET IT
  • Expanding the black box - depression, antidepressants, and the risk of suicide.  The New England journal of medicine2007 Academic Article GET IT
    Times cited: 74
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  • Uncovering an epidemic--screening for mental illness in teens.  The New England journal of medicine2006 Academic Article GET IT
    Times cited: 49
  • Violence and mental illness--how strong is the link?The New England journal of medicine2006 Academic Article GET IT
    Times cited: 67
  • The changing face of teenage drug abuse--the trend toward prescription drugs.  The New England journal of medicine2006 Academic Article GET IT
    Times cited: 73
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  • Disseminated intravascular coagulation and acute myoglobinuric renal failure: a consequence of the serotonergic syndrome.  Journal of clinical psychopharmacology1991 Academic Article GET IT
    Times cited: 22
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Research

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Grants awarded

  • Comparative Effectiveness of a Second Generation Antipsychotic or a Mood Stabilizer for Bipolar Disorder  awarded by Agency for Healthcare Research & Quality Key Personnel 2010 - 2013

Background

Contact

Primary Email

  • rafriedm@med.cornell.edu

Other

Primary Affiliation

  • Weill Cornell Medical College, Cornell University