Moonsoo Jin   Associate Professor of Biomedical Engineering in Radiology

Our research interests lie broadly in cancer immunotherapy and nanotechnology for early, sensitive detection of cancer and inflammation, and toward improved therapy through site-specific delivery of therapeutics. For these goals, we develop biomolecules (antibodies, nucleic acids, and other proteins), nano-sized particles, and engineered immune cells (T and NK cells), and validate these components in animal model of human diseases for their ability to detect and treat disease. We employ a variety of imaging techniques (whole body optical imaging, MRI, PET) to evaluate real-time distribution and targeted localization of particles and cells.

Current research topics include:

  • Global, unbiased mining of human antibodies maintaining natural pairing of Ig heavy and light chains
  • Engineering diagnostic and therapeutic nanoparticles toward cancer to allow image-guided drug delivery
  • Engineering of T/NK cells to recognize tumors through chimeric antigen receptor and magnetism-guided localization

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Background

Contact

Primary Email

  • moj2005@med.cornell.edu

Other

Primary Affiliation

  • Weill Cornell Medical College, Cornell University