selected publications
- Spatial Mapping of Human Hematopoiesis at Single Cell Resolution Reveals Aging-Associated Topographic Remodeling. Blood. 2023 Academic Article GET IT
- Detection of Hybrid Fusion Transcripts, Aberrant Transcript Expression and Specific Single Nucleotide Variants in Acute Leukemia and Myeloid Disorders with Recurrent Gene Rearrangements. Pathobiology : journal of immunopathology, molecular and cellular biology. 2023 Academic Article GET IT
- Molecular profiling of the stroke-induced alterations in the cerebral microvasculature reveals promising therapeutic candidates. Proceedings of the National Academy of Sciences of the United States of America. 2023 Academic Article GET IT
- Current Landscape of Ancillary Diagnostic Testing in Chronic Lymphocytic Leukemia. Surgical pathology clinics. 2023 Review GET IT
- Clinicopathologic characteristics of myeloproliferative neoplasms with JAK2 exon 12 mutation. Leukemia research. 2023 Academic Article GET IT
- Acute Hemolytic Anemia After Hematopoietic Stem Cell Transplantation: An Unusual Invader. 2023 GET IT
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A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas.
The Journal of clinical investigation.
2022
Academic Article
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Times cited: 6 - A novel SF3B1 variant in a patient with MDS with ring sideroblasts. EJHaem. 2022 Academic Article GET IT
- Comparison of Multiple Clinical Testing Modalities for Assessment of NPM1-Mutant AML. Frontiers in oncology. 2021 Academic Article GET IT
- Clinical Laboratory Validation and Implementation of Quantitative, Real-Time PCR-based Detection of NPM1 Type A Mutation. Clinical laboratory. 2020 Academic Article GET IT
- NPM1 Biology in Myeloid Neoplasia. Current hematologic malignancy reports. 2020 Information Resource GET IT
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Evaluation of S1PR1, pSTAT3, S1PR2, FOXP1 Expression in Aggressive, Mature B Cell Lymphomas.
Journal of hematopathology.
2019
Academic Article
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Times cited: 3 -
A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.
Cell reports.
2017
Academic Article
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Times cited: 54 - MRD in AML: a role for detecting leukemic blasts at day 14 post-induction chemotherapy?. Leukemia & lymphoma. 2017 Article GET IT
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The cancer precision medicine knowledge base for structured clinical-grade mutations and interpretations.
Journal of the American Medical Informatics Association : JAMIA.
2017
Academic Article
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Times cited: 78 -
Utility of Genomic Analysis in Differentiating Synchronous and Metachronous Lung Adenocarcinomas from Primary Adenocarcinomas with Intrapulmonary Metastasis.
Translational oncology.
2017
Academic Article
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Times cited: 39 -
Molecular Pathology: Predictive, Prognostic, and Diagnostic Markers in Lymphoid Neoplasms.
Surgical pathology clinics.
2016
Information Resource
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Times cited: 2 -
Development and validation of a whole-exome sequencing test for simultaneous detection of point mutations, indels and copy-number alterations for precision cancer care.
NPJ genomic medicine.
2016
Academic Article
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Times cited: 62 -
Validation and Implementation of a Custom Next-Generation Sequencing Clinical Assay for Hematologic Malignancies.
The Journal of molecular diagnostics : JMD.
2016
Academic Article
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Times cited: 127 -
Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
Oncogene.
2016
Academic Article
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Times cited: 68 -
An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma.
Nature genetics.
2016
Academic Article
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Times cited: 200 -
MYC Immunohistochemistry to Identify MYC-Driven B-Cell Lymphomas in Clinical Practice.
American journal of clinical pathology.
2016
Academic Article
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Times cited: 21 - Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case. Cold Spring Harbor molecular case studies. 2015 Academic Article GET IT
- Myeloid neoplasm demonstrating a STAT5B-RARA rearrangement and genetic alterations associated with all-trans retinoic acid resistance identified by a custom next-generation sequencing assay. Cold Spring Harbor molecular case studies. 2015 Academic Article GET IT
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Critical role of sphingosine-1-phosphate receptor-2 in the disruption of cerebrovascular integrity in experimental stroke.
Nature communications.
2015
Academic Article
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Times cited: 120 -
Age-related clonal hematopoiesis associated with adverse outcomes.
The New England journal of medicine.
2014
Academic Article
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Times cited: 3062 -
Molecular classification of MYC-driven B-cell lymphomas by targeted gene expression profiling of fixed biopsy specimens.
The Journal of molecular diagnostics : JMD.
2014
Academic Article
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Times cited: 22 -
Cyclin C is a haploinsufficient tumour suppressor.
Nature cell biology.
2014
Academic Article
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Times cited: 111 -
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
The Journal of molecular diagnostics : JMD.
2014
Academic Article
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Times cited: 69 -
Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma.
Cancer discovery.
2014
Academic Article
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Times cited: 110 -
NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis.
The Journal of investigative dermatology.
2014
Academic Article
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Times cited: 275 -
The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells.
Genes & development.
2014
Academic Article
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Times cited: 45 -
An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Nature genetics.
2014
Academic Article
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Times cited: 303 -
Detection of MYD88 L265P in peripheral blood of patients with Waldenström's Macroglobulinemia and IgM monoclonal gammopathy of undetermined significance.
Leukemia.
2014
Academic Article
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Times cited: 70 -
Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry.
PloS one.
2013
Academic Article
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Times cited: 90 -
Critical role of sphingosine-1-phosphate receptor 2 (S1PR2) in acute vascular inflammation.
Blood.
2013
Academic Article
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Times cited: 130 -
MYC, a downstream target of BRD-NUT, is necessary and sufficient for the blockade of differentiation in NUT midline carcinoma.
Oncogene.
2013
Academic Article
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Times cited: 139 -
Sphingosine-1-phosphate receptor 1 in classical Hodgkin lymphoma: assessment of expression and role in cell migration.
Laboratory investigation; a journal of technical methods and pathology.
2013
Academic Article
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Times cited: 37 -
Acute myeloid leukemia and myelodysplastic syndromes after radiation therapy are similar to de novo disease and differ from other therapy-related myeloid neoplasms.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2012
Academic Article
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Times cited: 83 -
Immunohistochemical detection of MYC-driven diffuse large B-cell lymphomas.
PloS one.
2012
Academic Article
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Times cited: 140 -
Polycomb repressive complex 2 is required for MLL-AF9 leukemia.
Proceedings of the National Academy of Sciences of the United States of America.
2012
Academic Article
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Times cited: 181 -
Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease.
JAMA.
2011
Academic Article
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Times cited: 303 -
TCR-dependent transformation of mature memory phenotype T cells in mice.
The Journal of clinical investigation.
2011
Academic Article
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Times cited: 63 -
Carcinoma and multiple lymphomas in one patient: establishing the diagnoses and analyzing risk factors.
Journal of hematopathology.
2009
Academic Article
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Times cited: 2 -
Frequency of clinically occult intraepithelial and invasive neoplasia in reduction mammoplasty specimens: a study of 516 cases.
International journal of surgical pathology.
2008
Academic Article
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Times cited: 36 -
Melanoma on the move: the progression of melanoma: novel concepts with histologic correlates.
The American Journal of dermatopathology.
2004
Information Resource
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Times cited: 8 -
Platelet-derived growth factor (PDGF)-induced chemotaxis does not require the G protein-coupled receptor S1P1 in murine embryonic fibroblasts and vascular smooth muscle cells.
FEBS letters.
2003
Academic Article
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Times cited: 33 -
Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors.
Biochimica et biophysica acta.
2002
Information Resource
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Times cited: 265 -
Lysophospholipids--receptor revelations.
Science (New York, N.Y.).
2001
Information Resource
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Times cited: 465 -
Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration.
Circulation research.
2001
Academic Article
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Times cited: 151 -
Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate.
Cell.
1999
Academic Article
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Times cited: 826