Loda, Massimo

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Blocking lipid synthesis induces DNA damage in prostate cancer and increases cell death caused by PARP inhibition. Science signaling. 2024 Academic Article GET IT
Canonical AREs are tumor suppressive regulatory elements in the prostate. 2024 GET IT
Author Correction: An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB. 2024 GET IT
Semi-Supervised, Attention-Based Deep Learning for Predicting TMPRSS2:ERG Fusion Status in Prostate Cancer Using Whole Slide Images. Molecular cancer research : MCR. 2024 Academic Article GET IT
Distinct mesenchymal cell states mediate prostate cancer progression. Nature communications. 2024 Academic Article GET IT
Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity. Cancer research. 2023 Academic Article GET IT
Linking African ancestral substructure to prostate cancer health disparities. Scientific reports. 2023 Academic Article GET IT
Plasma metabolomics profiling of 580 patients from an Early Detection Research Network prostate cancer cohort. Scientific data. 2023 Academic Article GET IT
Spatial transcriptomic analysis of virtual prostate biopsy reveals confounding effect of tissue heterogeneity on genomic signatures. Molecular cancer. 2023 Letter GET IT
Suppression of tumor cell lactate-generating signaling pathways eradicates murine PTEN/p53-deficient aggressive-variant prostate cancer via macrophage phagocytosis. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Metformin Overcomes the Consequences of NKX3.1 Loss to Suppress Prostate Cancer Progression. European urology. 2023 Academic Article GET IT
SPOP mutations target STING1 signaling in prostate cancer and create therapeutic vulnerabilities to PARP inhibitor-induced growth suppression. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer. Science translational medicine. 2023 Academic Article GET IT
PI-RADS 3 score: A retrospective experience of clinically significant prostate cancer detection. BJUI compass. 2023 Academic Article GET IT
Times cited: 64
The prostate stromal transcriptome in aggressive and lethal prostate cancer. Molecular cancer research : MCR. 2022 Academic Article GET IT
"Stromal cells in prostate cancer pathobiology: friends or foes?". British journal of cancer. 2022 Review GET IT
Castration-resistant prostate cancer cells are dependent on the high activity of CDK7. Journal of cancer research and clinical oncology. 2022 Academic Article GET IT
The AACR Journals: Advancing Progress Toward the AACR's 115-Year Mission. Blood cancer discovery. 2022 Academic Article GET IT
The AACR Journals: Advancing Progress Toward the AACR's 115-Year Mission. Cancer discovery. 2022 Academic Article GET IT
Druggable Metabolic Vulnerabilities Are Exposed and Masked during Progression to Castration Resistant Prostate Cancer. Biomolecules. 2022 Review GET IT
Randomized Trial of Olaparib With or Without Cediranib for Metastatic Castration-Resistant Prostate Cancer: The Results From National Cancer Institute 9984. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2022 Academic Article GET IT
A MIR17HG-derived Long Noncoding RNA Provides an Essential Chromatin Scaffold for Protein Interaction and Myeloma Growth. Blood. 2022 Academic Article GET IT
Transcriptomes of prostate cancer with TMPRSS2:ERG and other ETS fusions. Molecular cancer research : MCR. 2022 Academic Article GET IT
Circulating Cell-Free DNA in Renal Cell Carcinoma: The New Era of Precision Medicine. Cancers. 2022 Review GET IT
The prostate cancer androgen receptor cistrome in African American men associates with upregulation of lipid metabolism and immune response. Cancer research. 2022 Academic Article GET IT
Rare Germline Variants Are Associated with Rapid Biochemical Recurrence After Radical Prostate Cancer Treatment: A Pan Prostate Cancer Group Study. European urology. 2022 Academic Article GET IT
Pyruvate kinase M1 suppresses development and progression of prostate adenocarcinoma. Cancer research. 2022 Academic Article GET IT
MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets. Nature communications. 2022 Academic Article GET IT
Fatty acid synthase as a potential new therapeutic target for cervical cancer. Anais da Academia Brasileira de Ciencias. 2022 Academic Article GET IT
A multidisciplinary approach to optimize primary prostate cancer biobanking. Urologic oncology. 2022 Academic Article GET IT
Intra-epithelial non-canonical Activin A signaling safeguards prostate progenitor quiescence. EMBO reports. 2022 Academic Article GET IT
O-GlcNAc transferase couples MRE11 to transcriptionally active chromatin to suppress DNA damage. Journal of biomedical science. 2022 Academic Article GET IT
Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer. Molecular cancer research : MCR. 2022 Academic Article GET IT
Implementation of a prostate cancer-specific targeted sequencing panel for credentialing of patient-derived cell lines and genomic characterization of patient samples. The Prostate. 2022 Academic Article GET IT
Extent, impact, and mitigation of batch effects in tumor biomarker studies using tissue microarrays. eLife. 2021 Academic Article GET IT
Building tools for machine learning and artificial intelligence in cancer research: best practices and a case study with the PathML toolkit for computational pathology. Molecular cancer research : MCR. 2021 Academic Article GET IT
Inhibition of CDK9 activity compromises global splicing in prostate cancer cells. RNA biology. 2021 Academic Article GET IT
PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis. Molecular cell. 2021 Academic Article GET IT
Times cited: 11
Inflammatory metabolic profile of South African patients with prostate cancer. Cancer & metabolism. 2021 Academic Article GET IT
Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer. Nature communications. 2021 Academic Article GET IT
The New York State SARS-CoV-2 Testing Consortium: Regional Communication in Response to the COVID-19 Pandemic. Academic pathology. 2021 Academic Article GET IT
Times cited: 4
EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer. Nature cancer. 2021 Academic Article GET IT
Times cited: 110
Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions. Nature communications. 2021 Academic Article GET IT
Times cited: 81
Association of Prediagnostic Blood Metabolomics with Prostate Cancer Defined by ERG or PTEN Molecular Subtypes. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2021 Academic Article GET IT
ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer. Cancer research. 2021 Academic Article GET IT
Times cited: 7
Gene Expression Pathways in Prostate Tissue Associated with Vigorous Physical Activity in Prostate Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2021 Academic Article GET IT
Ductal adenocarcinoma of the prostate: A systematic review and meta-analysis of incidence, presentation, prognosis, and management. BJUI compass. 2021 Review GET IT
Genetic ablation of FASN attenuates the invasive potential of prostate cancer driven by Pten loss. The Journal of pathology. 2020 Academic Article GET IT
Times cited: 13
Rapid Implementation of Severe Acute Respiratory Syndrome Coronavirus 2 Emergency Use Authorization RT-PCR Testing and Experience at an Academic Medical Institution. The Journal of molecular diagnostics : JMD. 2020 Academic Article GET IT
Times cited: 3
Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and Serum. Molecular cancer research : MCR. 2020 Academic Article GET IT
Times cited: 19
Routine Laboratory Blood Tests Predict SARS-CoV-2 Infection Using Machine Learning. Clinical chemistry. 2020 Academic Article GET IT
Times cited: 72
COVID-19 Viral and Serology Testing in New York City Health Care Workers. American journal of clinical pathology. 2020 Academic Article GET IT
Times cited: 10
Exploring a role for fatty acid synthase in prostate cancer cell migration. Small GTPases. 2020 Academic Article GET IT
Association between CD8 and PD-L1 expression and outcomes after radical prostatectomy for localized prostate cancer. The Prostate. 2020 Academic Article GET IT
Times cited: 1
SARS-CoV-2 Viral Load Predicts Mortality in Patients with and without Cancer Who Are Hospitalized with COVID-19. Cancer cell. 2020 Academic Article GET IT
Times cited: 163
A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors. eLife. 2020 Academic Article GET IT
Times cited: 48
Evidence that EZH2 Deregulation is an Actionable Therapeutic Target for Prevention of Prostate Cancer. Cancer prevention research (Philadelphia, Pa.). 2020 Academic Article GET IT
Multiplex Immunofluorescence in Formalin-Fixed Paraffin-Embedded Tumor Tissue to Identify Single-Cell-Level PI3K Pathway Activation. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Academic Article GET IT
Systematic Assessment of Tumor Purity and Its Clinical Implications. JCO precision oncology. 2020 Academic Article GET IT
Times cited: 22
Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome. Blood. 2020 Academic Article GET IT
Times cited: 951
Comparison of Two High-Throughput Reverse Transcription-PCR Systems for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2. Journal of clinical microbiology. 2020 Academic Article GET IT
Times cited: 44
Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention. Advanced drug delivery reviews. 2020 Information Resource GET IT
Times cited: 289
Tumor protein expression of the DNA repair gene BRCA1 and lethal prostate cancer. Carcinogenesis. 2020 Academic Article GET IT
Inferior Cancer Survival for Men with Localized High-grade Prostate Cancer but Low Prostate-specific Antigen. European urology. 2020 Article GET IT
Inhibition of O-GlcNAc Transferase Renders Prostate Cancer Cells Dependent on CDK9. Molecular cancer research : MCR. 2020 Academic Article GET IT
Phase I study of the ¹⁷⁷Lu-DOTA⁰-Tyr³-Octreotate (lutathera) in combination with nivolumab in patients with neuroendocrine tumors of the lung. Journal for immunotherapy of cancer. 2020 Academic Article GET IT
Times cited: 44
SARS-CoV-2 antibody characterization in emergency department, hospitalized and convalescent patients by two semi-quantitative immunoassays. Clinica chimica acta; international journal of clinical chemistry. 2020 Academic Article GET IT
Times cited: 29
Lipogenic signalling modulates prostate cancer cell adhesion and migration via modification of Rho GTPases. Oncogene. 2020 Academic Article GET IT
Times cited: 38
BCL9 provides multi-cellular communication properties in colorectal cancer by interacting with paraspeckle proteins. Nature communications. 2020 Academic Article GET IT
Times cited: 29
Statin Use Is Associated with Lower Risk of PTEN-Null and Lethal Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 33
CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer. Cell reports. 2019 Academic Article GET IT
Times cited: 34
Reply to 'H-STS, L-STS and KRJ-I are not authentic GEPNET cell lines'. Nature genetics. 2019 Article GET IT
Times cited: 8
High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program. Nature communications. 2019 Academic Article GET IT
Times cited: 89
A Prospective Study of Intraprostatic Inflammation, Focal Atrophy, and Progression to Lethal Prostate Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2019 Academic Article GET IT
Times cited: 12
Family history of prostate cancer and the incidence of ERG- and phosphatase and tensin homolog-defined prostate cancer. International journal of cancer. 2019 Academic Article GET IT
Aneuploidy drives lethal progression in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 2019 Academic Article GET IT
Times cited: 79
Genomic correlates of clinical outcome in advanced prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 2019 Academic Article GET IT
Times cited: 707
When fat goes down, prostate cancer is on the ropes. Molecular & cellular oncology. 2019 Academic Article GET IT
Times cited: 4
AKT1^low quiescent cancer cells in ductal carcinoma in situ of the breast. NPJ breast cancer. 2019 Academic Article GET IT
Times cited: 3
Molecular Characterization of Prostate Cancer with Associated Gleason Score Using Mass Spectrometry Imaging. Molecular cancer research : MCR. 2019 Academic Article GET IT
Times cited: 47
Expression of IGF/insulin receptor in prostate cancer tissue and progression to lethal disease. Carcinogenesis. 2018 Academic Article GET IT
Times cited: 35
Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 2018 Academic Article GET IT
Times cited: 176
Compound Genomic Alterations of TP53, PTEN, and RB1 Tumor Suppressors in Localized and Metastatic Prostate Cancer. European urology. 2018 Academic Article GET IT
Times cited: 62
Transcriptome Deconvolution of Heterogeneous Tumor Samples with Immune Infiltration. iScience. 2018 Academic Article GET IT
Times cited: 45
Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate. Molecular cancer research : MCR. 2018 Academic Article GET IT
Times cited: 40
Re: Melissa Assel, Anders Dahlin, David Ulmert, et al. Association Between Lead Time and Prostate Cancer Grade: Evidence of Grade Progression from Long-term Follow-up of Large Population-based Cohorts Not Subject to Prostate-specific Antigen Screening. Eur Urol 2018;73:961-7. European urology. 2018 Article GET IT
Loss of PTEN Expression Detected by Fluorescence Immunohistochemistry Predicts Lethal Prostate Cancer in Men Treated with Prostatectomy. European urology oncology. 2018 Academic Article GET IT
Times cited: 8
Metabolic Vulnerabilities of Prostate Cancer: Diagnostic and Therapeutic Opportunities. Cold Spring Harbor perspectives in medicine. 2018 Information Resource GET IT
Times cited: 42
A Prospective Study of Aspirin Use and Prostate Cancer Risk by TMPRSS2:ERG Status. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2018 Academic Article GET IT
Times cited: 2
The Metabolic Landscape of Prostate Cancer. European urology oncology. 2018 Information Resource GET IT
Times cited: 25
Neoadjuvant-Intensive Androgen Deprivation Therapy Selects for Prostate Tumor Foci with Diverse Subclonal Oncogenic Alterations. Cancer research. 2018 Academic Article GET IT
Times cited: 50
Specific ¹⁸F-FDHT Accumulation in Human Prostate Cancer Xenograft Murine Models Is Facilitated by Prebinding to Sex Hormone-Binding Globulin. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2018 Academic Article GET IT
Times cited: 2
LSD1: A single target to combat lineage plasticity in lethal prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 2018 Article GET IT
Times cited: 15
Fatty Acid Synthase and Acetyl-CoA Carboxylase Are Expressed in Nodal Metastatic Melanoma But Not in Benign Intracapsular Nodal Nevi. The American Journal of dermatopathology. 2018 Academic Article GET IT
Times cited: 22
Systematic identification of functionally relevant risk alleles to stratify aggressive versus indolent prostate cancer. Oncotarget. 2018 Academic Article GET IT
Times cited: 10
Height, Obesity, and the Risk of TMPRSS2:ERG-Defined Prostate Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2017 Academic Article GET IT
Times cited: 19
MYC Overexpression at the Protein and mRNA Level and Cancer Outcomes among Men Treated with Radical Prostatectomy for Prostate Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2017 Academic Article GET IT
Times cited: 20
AKT1^low Quiescent Cancer Cells Promote Solid Tumor Growth. Molecular cancer therapeutics. 2017 Academic Article GET IT
Times cited: 16
Expression of PD-L1 in Hormone-naïve and Treated Prostate Cancer Patients Receiving Neoadjuvant Abiraterone Acetate plus Prednisone and Leuprolide. Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Academic Article GET IT
Times cited: 42
Stromal and epithelial transcriptional map of initiation progression and metastatic potential of human prostate cancer. Nature communications. 2017 Academic Article GET IT
AKT1^low quiescent cancer cells persist after neoadjuvant chemotherapy in triple negative breast cancer. Breast cancer research : BCR. 2017 Academic Article GET IT
Times cited: 19
Metformin and longevity (METAL): a window of opportunity study investigating the biological effects of metformin in localised prostate cancer. BMC cancer. 2017 Academic Article GET IT
Times cited: 20
Gene expression profiling of prostate tissue identifies chromatin regulation as a potential link between obesity and lethal prostate cancer. Cancer. 2017 Academic Article GET IT
Times cited: 11
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proceedings of the National Academy of Sciences of the United States of America. 2017 Academic Article GET IT
Times cited: 219
Interpathologist concordance in the histological diagnosis of focal prostatic atrophy lesions, acute and chronic prostatitis, PIN, and prostate cancer. Virchows Archiv : an international journal of pathology. 2017 Academic Article GET IT
Times cited: 7
Association of Tissue Abiraterone Levels and SLCO Genotype with Intraprostatic Steroids and Pathologic Response in Men with High-Risk Localized Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2017 Academic Article GET IT
Times cited: 29
Circulating Antioxidant Levels and Risk of Prostate Cancer by TMPRSS2:ERG. The Prostate. 2017 Academic Article GET IT
Times cited: 7
Metabolic Profiling in Formalin-Fixed and Paraffin-Embedded Prostate Cancer Tissues. Molecular cancer research : MCR. 2017 Academic Article GET IT
Times cited: 45
Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance. Science (New York, N.Y.). 2017 Academic Article GET IT
Times cited: 690
Pathology-Driven Comprehensive Proteomic Profiling of the Prostate Cancer Tumor Microenvironment. Molecular cancer research : MCR. 2017 Academic Article GET IT
Times cited: 9
ALK gene copy number in lung cancer: Unspecific polyploidy versus specific amplification visible as double minutes. Cancer biomarkers : section A of Disease markers. 2017 Academic Article GET IT
Times cited: 2
Loss of RasGAP Tumor Suppressors Underlies the Aggressive Nature of Luminal B Breast Cancers. Cancer discovery. 2016 Academic Article GET IT
Times cited: 43
The role of tumor metabolism as a driver of prostate cancer progression and lethal disease: results from a nested case-control study. Cancer & metabolism. 2016 Academic Article GET IT
Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer. The Journal of clinical investigation. 2016 Academic Article GET IT
Prognostic Utility of a New mRNA Expression Signature of Gleason Score. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 Academic Article GET IT
Times cited: 50
Vascular morphology differentiates prostate cancer mortality risk among men with higher Gleason grade. Cancer causes & control : CCC. 2016 Academic Article GET IT
Times cited: 6
Calcium-Sensing Receptor Tumor Expression and Lethal Prostate Cancer Progression. The Journal of clinical endocrinology and metabolism. 2016 Academic Article GET IT
Times cited: 28
Pre-diagnostic circulating sex hormone levels and risk of prostate cancer by ERG tumour protein expression. British journal of cancer. 2016 Academic Article GET IT
Times cited: 17
Risk of prostate cancer-specific death in men with baseline metabolic aberrations treated with androgen deprivation therapy for biochemical recurrence. BJU international. 2016 Academic Article GET IT
Times cited: 9
Association of Prostate Cancer Risk Variants with TMPRSS2:ERG Status: Evidence for Distinct Molecular Subtypes. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2016 Academic Article GET IT
Times cited: 20
The Proliferative Activity of Mammary Epithelial Cells in Normal Tissue Predicts Breast Cancer Risk in Premenopausal Women. Cancer research. 2016 Academic Article GET IT
Times cited: 40
Dietary lycopene intake and risk of prostate cancer defined by ERG protein expression. The American journal of clinical nutrition. 2016 Academic Article GET IT
Times cited: 65
Profiling the tumor microenvironment proteome in prostate cancer using laser capture microdissection coupled to LC⿿MS⿿A technical report. EuPA open proteomics. 2015 Academic Article GET IT
Times cited: 12
Expression Levels of DNA Damage Repair Proteins Are Associated With Overall Survival in Platinum-Treated Advanced Urothelial Carcinoma. Clinical genitourinary cancer. 2015 Academic Article GET IT
Times cited: 34
Overexpression of the Long Non-coding RNA SChLAP1 Independently Predicts Lethal Prostate Cancer. European urology. 2015 Academic Article GET IT
Times cited: 104
A Prospective Investigation of PTEN Loss and ERG Expression in Lethal Prostate Cancer. Journal of the National Cancer Institute. 2015 Academic Article GET IT
Times cited: 151
Advanced neuroendocrine prostate tumors regress to stemness. Proceedings of the National Academy of Sciences of the United States of America. 2015 Article GET IT
Times cited: 11
The Molecular Taxonomy of Primary Prostate Cancer. Cell. 2015 Academic Article GET IT
Times cited: 2119
A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men. EBioMedicine. 2015 Academic Article GET IT
Times cited: 55
Stress-Related Signaling Pathways in Lethal and Nonlethal Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 Academic Article GET IT
Times cited: 23
The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis. Nature genetics. 2015 Academic Article GET IT
Times cited: 269
MicroRNA MIR21 and T Cells in Colorectal Cancer. Cancer immunology research. 2015 Academic Article GET IT
Times cited: 30
Evaluating a 4-marker signature of aggressive prostate cancer using time-dependent AUC. The Prostate. 2015 Academic Article GET IT
Times cited: 6
Paired exome analysis of Barrett's esophagus and adenocarcinoma. Nature genetics. 2015 Academic Article GET IT
Times cited: 268
A Phase I/II Study for Analytic Validation of 89Zr-J591 ImmunoPET as a Molecular Imaging Agent for Metastatic Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 Academic Article GET IT
Times cited: 159
Detecting metastatic prostate carcinoma in pelvic lymph nodes following neoadjuvant hormone therapy: the eyes have it!. Histopathology. 2015 Academic Article GET IT
Times cited: 5
Measuring PI3K Activation: Clinicopathologic, Immunohistochemical, and RNA Expression Analysis in Prostate Cancer. Molecular cancer research : MCR. 2015 Academic Article GET IT
Times cited: 15
Integrative clinical genomics of advanced prostate cancer. Cell. 2015 Academic Article GET IT
Times cited: 2331
Dissecting the Dual Role of AMPK in Cancer: From Experimental to Human Studies. Molecular cancer research : MCR. 2015 Information Resource GET IT
Times cited: 148
Comparing Platforms for Messenger RNA Expression Profiling of Archival Formalin-Fixed, Paraffin-Embedded Tissues. The Journal of molecular diagnostics : JMD. 2015 Academic Article GET IT
Times cited: 19
Molecular differences in transition zone and peripheral zone prostate tumors. Carcinogenesis. 2015 Academic Article GET IT
Times cited: 32
Tumor expression of adiponectin receptor 2 and lethal prostate cancer. Carcinogenesis. 2015 Academic Article GET IT
Times cited: 24
DNA copy number analysis of metastatic urothelial carcinoma with comparison to primary tumors. BMC cancer. 2015 Academic Article GET IT
Times cited: 21
26th Pezcoller symposium: cancers driven by hormones. Cancer research. 2015 Conference Paper GET IT
Coordinate loss of MAP3K7 and CHD1 promotes aggressive prostate cancer. Cancer research. 2015 Academic Article GET IT
Times cited: 73
Development and clinical validation of an in situ biopsy-based multimarker assay for risk stratification in prostate cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 Academic Article GET IT
Times cited: 89
The TMPRSS2:ERG fusion and response to androgen deprivation therapy for prostate cancer. The Prostate. 2015 Academic Article GET IT
Times cited: 25
Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneity. Nature communications. 2015 Academic Article GET IT
Times cited: 224
HER2 as a target in invasive urothelial carcinoma. Cancer medicine. 2015 Academic Article GET IT
Times cited: 39
Untargeted metabolomics for profiling oncogene-specific metabolic signatures of prostate cancer. Molecular & cellular oncology. 2015 Academic Article GET IT
Times cited: 4
Role of diet in prostate cancer: the epigenetic link. Oncogene. 2014 Information Resource GET IT
Times cited: 40
A novel role for microphthalmia-associated transcription factor-regulated pigment epithelium-derived factor during melanoma progression. The American journal of pathology. 2014 Academic Article GET IT
Times cited: 17
Association of prostate cancer risk variants with gene expression in normal and tumor tissue. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2014 Academic Article GET IT
Times cited: 85
Combined MEK and PI3K inhibition in a mouse model of pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2014 Academic Article GET IT
Times cited: 104
A phase I study of everolimus and docetaxel in patients with castration-resistant prostate cancer. Clinical genitourinary cancer. 2014 Academic Article GET IT
Times cited: 31
AKT1 and MYC induce distinctive metabolic fingerprints in human prostate cancer. Cancer research. 2014 Academic Article GET IT
Times cited: 115
Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors. Clinical cancer research : an official journal of the American Association for Cancer Research. 2014 Academic Article GET IT
Times cited: 144
Intense androgen-deprivation therapy with abiraterone acetate plus leuprolide acetate in patients with localized high-risk prostate cancer: results of a randomized phase II neoadjuvant study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2014 Academic Article GET IT
Times cited: 215
⁸⁹Zr-huJ591 immuno-PET imaging in patients with advanced metastatic prostate cancer. European journal of nuclear medicine and molecular imaging. 2014 Academic Article GET IT
Times cited: 123
5α-Reductase inhibitors and risk of high-grade or lethal prostate cancer. JAMA internal medicine. 2014 Academic Article GET IT
Times cited: 32
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas. The Journal of pathology. 2014 Academic Article GET IT
Times cited: 28
Identification of proteomic biomarkers predicting prostate cancer aggressiveness and lethality despite biopsy-sampling error. British journal of cancer. 2014 Academic Article GET IT
Times cited: 107
Androgen receptor CAG repeat polymorphism and risk of TMPRSS2:ERG-positive prostate cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2014 Academic Article GET IT
Times cited: 24
Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition. Cancer discovery. 2014 Academic Article GET IT
Times cited: 80
FGFR3 expression in primary and metastatic urothelial carcinoma of the bladder. Cancer medicine. 2014 Academic Article GET IT
Times cited: 76
Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer. Nature biotechnology. 2014 Academic Article GET IT
Times cited: 459
SPINK1 protein expression and prostate cancer progression. Clinical cancer research : an official journal of the American Association for Cancer Research. 2014 Academic Article GET IT
Times cited: 61
A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis. EMBO molecular medicine. 2014 Academic Article GET IT
Times cited: 164
High-resolution array CGH and gene expression profiling of alveolar soft part sarcoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2014 Academic Article GET IT
Times cited: 29
Integrative analysis of 1q23.3 copy-number gain in metastatic urothelial carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2014 Academic Article GET IT
Times cited: 55
Dietary lycopene, angiogenesis, and prostate cancer: a prospective study in the prostate-specific antigen era. Journal of the National Cancer Institute. 2014 Academic Article GET IT
Times cited: 177
De novo fatty acid synthesis at the mitotic exit is required to complete cellular division. Cell cycle (Georgetown, Tex.). 2014 Academic Article GET IT
Times cited: 67
Modification of the association between obesity and lethal prostate cancer by TMPRSS2:ERG. Journal of the National Cancer Institute. 2013 Academic Article GET IT
Times cited: 74
Prostate-specific membrane antigen protein expression in tumor tissue and risk of lethal prostate cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2013 Academic Article GET IT
Times cited: 94
Twenty-fifth annual Pezcoller Symposium: Metabolism and tumorigenesis. Cancer research. 2013 Conference Paper GET IT
USP2a alters chemotherapeutic response by modulating redox. Cell death & disease. 2013 Academic Article GET IT
Times cited: 26
Blood levels of saturated and monounsaturated fatty acids as markers of de novo lipogenesis and risk of prostate cancer. American journal of epidemiology. 2013 Academic Article GET IT
Times cited: 46
Protein expression of PTEN, insulin-like growth factor I receptor (IGF-IR), and lethal prostate cancer: a prospective study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2013 Academic Article GET IT
Times cited: 36
Gleason grade progression is uncommon. Cancer research. 2013 Academic Article GET IT
Times cited: 65
A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer. Nature genetics. 2013 Academic Article GET IT
Times cited: 129
The fat side of prostate cancer. Biochimica et biophysica acta. 2013 Information Resource GET IT
Times cited: 219
ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients. Genes & development. 2013 Academic Article GET IT
Times cited: 138
ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer. The Journal of clinical investigation. 2013 Academic Article GET IT
Times cited: 151
Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention. Cancer discovery. 2012 Academic Article GET IT
Times cited: 43
EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent. Science (New York, N.Y.). 2012 Academic Article GET IT
Times cited: 682
A synthetic form of frizzled 8-associated antiproliferative factor enhances p53 stability through USP2a and MDM2. PloS one. 2012 Academic Article GET IT
Times cited: 8
Selenoprotein P genetic variants and mrna expression, circulating selenium, and prostate cancer risk and survival. The Prostate. 2012 Academic Article GET IT
Times cited: 26
Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 2012 Academic Article GET IT
Times cited: 87
The ubiquitin-specific protease USP2a prevents endocytosis-mediated EGFR degradation. Oncogene. 2012 Academic Article GET IT
Times cited: 50
DNA fragmentation simulation method (FSM) and fragment size matching improve aCGH performance of FFPE tissues. PloS one. 2012 Academic Article GET IT
Times cited: 27
c-Met, epidermal growth factor receptor, and insulin-like growth factor-1 receptor are important for growth in uveal melanoma and independently contribute to migration and metastatic potential. Melanoma research. 2012 Academic Article GET IT
Times cited: 37
Utility of multispectral imaging in automated quantitative scoring of immunohistochemistry. Journal of clinical pathology. 2012 Academic Article GET IT
Times cited: 48
The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer. Cell cycle (Georgetown, Tex.). 2012 Academic Article GET IT
Times cited: 69
MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer. Cancer discovery. 2012 Academic Article GET IT
Times cited: 74
Effect of dietary polyunsaturated fatty acids on castration-resistant Pten-null prostate cancer. Carcinogenesis. 2011 Academic Article GET IT
Times cited: 42
Prognostic determinants in prostate cancer. Cancer journal (Sudbury, Mass.). 2011 Information Resource GET IT
Times cited: 46
Common polymorphisms in the adiponectin and its receptor genes, adiponectin levels and the risk of prostate cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2011 Academic Article GET IT
Times cited: 56
A comprehensive analysis of PAX8 expression in human epithelial tumors. The American journal of surgical pathology. 2011 Academic Article GET IT
Times cited: 287
Vitamin D receptor protein expression in tumor tissue and prostate cancer progression. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2011 Academic Article GET IT
Times cited: 127
mRNA expression signature of Gleason grade predicts lethal prostate cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2011 Academic Article GET IT
Times cited: 125
β-Catenin is a useful adjunct immunohistochemical marker for the diagnosis of pulmonary lymphangioleiomyomatosis. American journal of clinical pathology. 2011 Academic Article GET IT
Times cited: 24
Differential expression of S6K2 dictates tissue-specific requirement for S6K1 in mediating aberrant mTORC1 signaling and tumorigenesis. Cancer research. 2011 Academic Article GET IT
Times cited: 20
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Times cited: 65
The DCC protein and colon cancer. The New England journal of medicine. 1997 Article GET IT
The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinomas. Cancer research. 1997 Academic Article GET IT
Times cited: 337
Association between sucrase-isomaltase and p53 expression in colorectal cancer. Annals of surgical oncology. 1997 Academic Article GET IT
Times cited: 2
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer research. 1997 Academic Article GET IT
Times cited: 1292
Lymph node negative invasive breast carcinoma 1 centimeter or less in size (T1a,bNOMO): clinicopathologic features and outcome. Cancer. 1997 Academic Article GET IT
Times cited: 73
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nature medicine. 1997 Academic Article GET IT
Times cited: 985
Mitogen-activated protein kinase phosphatase 1 is overexpressed in prostate cancers and is inversely related to apoptosis. Laboratory investigation; a journal of technical methods and pathology. 1997 Academic Article GET IT
Times cited: 150
The DCC protein and prognosis in colorectal cancer. The New England journal of medicine. 1996 Academic Article GET IT
Times cited: 264
Thymosin beta 15: a novel regulator of tumor cell motility upregulated in metastatic prostate cancer. Nature medicine. 1996 Academic Article GET IT
Times cited: 138
Expression of mitogen-activated protein kinase phosphatase-1 in the early phases of human epithelial carcinogenesis. The American journal of pathology. 1996 Academic Article GET IT
Times cited: 172
Mitogen-activated protein kinase and mitogen-activated kinase phosphatase-1 expression in the Noble rat model of sex hormone-induced prostatic dysplasia and carcinoma. Laboratory investigation; a journal of technical methods and pathology. 1996 Academic Article GET IT
Times cited: 39
Hepatitis C virus reinfection in orthotopic liver transplant patients with or without concomitant hepatitis B infection. Diagnostic molecular pathology : the American journal of surgical pathology, part B. 1996 Academic Article GET IT
Times cited: 9
Male breast carcinoma: an evaluation of prognostic factors contributing to a poorer outcome. Cancer. 1996 Academic Article GET IT
Times cited: 201
Cell cycle and cancer: critical events at the G1 restriction point. Critical reviews in oncogenesis. 1996 Information Resource GET IT
Times cited: 76
Detection of p53 mutations by single-strand conformation polymorphisms (SSCP) gel electrophoresis. A comparative study of radioactive and nonradioactive silver-stained SSCP analysis. Diagnostic molecular pathology : the American journal of surgical pathology, part B. 1995 Academic Article GET IT
Times cited: 59
Sucrase-isomaltase is an independent prognostic marker for colorectal carcinoma. Diseases of the colon and rectum. 1995 Academic Article GET IT
Times cited: 18
CDC25 phosphatases as potential human oncogenes. Science (New York, N.Y.). 1995 Academic Article GET IT
Times cited: 490
Cyclic adenosine monophosphate can convert epidermal growth factor into a differentiating factor in neuronal cells. The Journal of biological chemistry. 1995 Academic Article GET IT
Times cited: 55
Increased incidence of p53 mutations is associated with hepatic metastasis in colorectal neoplastic progression. Oncogene. 1995 Academic Article GET IT
Times cited: 81
Thrombopoietin receptor expression in human cancer cell lines and primary tissues. Cancer research. 1995 Academic Article GET IT
Times cited: 63
Nodular foci in parathyroid adenomas and hyperplasias: an immunohistochemical analysis of proliferative activity. Human pathology. 1994 Academic Article GET IT
Times cited: 47
The somatostatin receptor SSTR1 is coupled to phosphotyrosine phosphatase activity in CHO-K1 cells. Molecular endocrinology (Baltimore, Md.). 1994 Academic Article GET IT
Times cited: 84
Androgen receptor immunohistochemistry on paraffin-embedded tissue. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 1994 Academic Article GET IT
Times cited: 26
N-myc gene amplification/expression in localized stroma-rich neuroblastoma (ganglioneuroblastoma). Human pathology. 1993 Academic Article GET IT
Times cited: 22
p53 gene mutations in medulloblastoma. Immunohistochemistry, gel shift analysis, and sequencing. Diagnostic molecular pathology : the American journal of surgical pathology, part B. 1993 Academic Article GET IT
Large-cell medulloblastomas. A distinct variant with highly aggressive behavior. The American journal of surgical pathology. 1992 Academic Article GET IT
Times cited: 151
Quantitative DNA analysis and proliferation in breast carcinomas. A comparison between image analysis and flow cytometry. Pathology, research and practice. 1992 Academic Article GET IT
Times cited: 16
p53 gene expression in medulloblastoma by quantitative polymerase chain reaction. Diagnostic molecular pathology : the American journal of surgical pathology, part B. 1992 Academic Article GET IT
Times cited: 8
DNA ploidy, proliferation, and neu-oncogene protein overexpression in breast carcinoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 1992 Academic Article GET IT
Times cited: 38
Detection of K-ras mutations in pancreatic and hepatic neoplasms by non-isotopic mismatched polymerase chain reaction. Oncogene. 1991 Academic Article GET IT
Times cited: 88
Prognosis and survival as determined by visceral amino acid clearance in severe trauma. The Journal of trauma. 1985 Academic Article GET IT
Times cited: 44
Tumor-associated metabolism in the rat is a unique physiologic entity. The Journal of surgical research. 1985 Academic Article GET IT
Times cited: 10
Amino acid clearance and prognosis in surgical patients with cirrhosis. Surgery. 1984 Academic Article GET IT
Times cited: 47
Induction of hepatic protein synthesis by a peptide in blood plasma of patients with sepsis and trauma. Surgery. 1984 Academic Article GET IT
Times cited: 21
Encephalopathy, oxygen consumption, visceral amino acid clearance, and mortality in cirrhotic surgical patients. American journal of surgery. 1984 Academic Article GET IT
Times cited: 16

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Research

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Co-investigator Network

Funding awarded

Targeting lipid metabolism and diet in patients with locally advanced prostate cancer awarded by Prostate Cancer Foundation Principal Investigator 2023 - 2023

Untangle The Role of Tumor Microenvironment in Prostate Cancer Initiation, Progression, and Metastatization With Single-Cell Analysis Technologies awarded by American Italian Cancer Foundation Co-Principal Investigator 2024 - 2025

Characterizing 3''-UTR biology as a mechanism of therapy response in high risk prostate cancer. awarded by United States Department of Defense Key Personnel 2024 - 2027
Loss of Stromal Androgen Receptor (AR) Signaling Contributes to Progression in Prostate Cancer awarded by American Italian Cancer Foundation Key Personnel 2023 - 2024
Colorectal Cancer (CRC) Cellular Heterogeneity, Metastasis, and a Spatially-resolved Molecular Atlas for Colon awarded by Gastro-Intestinal Research Foundation Key Personnel 2022 - 2024
Deciphering the role of androgen receptor in spatially resolved mesenchymal populations in prostate cancer awarded by Fondazione AIRC per la Ricerca sul Cancro Key Personnel 2022 - 2024

Investigating cell-intrinsic and extrinsic interactions in prostate cancer at the single cell level ("Core A: Pathobiology") awarded by National Institute of Mental Health Principal Investigator Subaward 2022 - 2027
Genomic Diversity of Prostate Cancer Across the African Diaspora awarded by National Cancer Institute Principal Investigator Subaward 2022 - 2026
High-risk prostate cancer in southern Africa, unravelling the genome and exposome (TARGET Africa) awarded by United States Department of Defense Principal Investigator Subaward 2022 - 2025
Neuronal function and incurable prostate cancer (DOD W81XWH-21-PCRP-IDA) awarded by New York Genome Center Inc. Principal Investigator Subaward 2022 - 2025

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Background

education and training

M.D., University of Milan Faculty of Medicine and Surgery (Italy) 1980

Contact

full name

Massimo Loda

primary email

mloda@med.cornell.edu

webpage

Clinical Profile

VIVO Weill Cornell Medical College

Massimo Loda Chair of Pathology and Laboratory Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage

Phone

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage