Laibaik Park   Assistant Professor of Research in Neuroscience

Cerebrovascular regulation.

Dr. Park is interested in understanding the regulatory mechanisms of cerebrovascular microcirculation that insure a constant supply of blood to the brain at all times. To study the regulatory mechanisms in normal and diseased brain, Dr. Park employs a combination of in vivo and in vitro techniques, including craniotomy, electrophysiology, immunofluorescence, molecular biological techniques, and behavioral analysis. The brain is highly dependent on a well-regulated blood supply in order to function normally. Abnormalities in the mechanisms are implicated in various cerebrovascular diseases, including stroke and Alzheimer’s disease. Dr. Park's research focuses on a role of vascular factors, such as ß-amyloid and tissue plasminogen activator, in the mechanisms of cerebrovascular regulation and the cellular and molecular mechanisms of cerebrovascular alterations leading to behavioral abnormalities. For more information, please visit our website at:http://www.cornellneurology.org/neurobiology

Publications

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Research

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Grants awarded

  • tPA Deficiency and Neurovascular Dysfunction in Models of Alzheimer's Disease  awarded by American Heart Association Principal Investigator 2009 - 2013
  • Experimental Neurogenic Hypertension Program  awarded by National Heart, Lung, & Blood Institute Key Personnel 2004 - 2009
  • Overexpression of APP and Cerebrovascular Regulation  awarded by National Institute of Neurological Disorders & Stroke Key Personnel 2012 -
  • Stalled Capillary Flow: A Novel Mechanism for Hypoperfusion in Alzheimer Disease  awarded by National Institute on Aging Principal Investigator Subaward 2015 -

Background

Contact

Primary Email

  • lap2003@med.cornell.edu

Other

Primary Affiliation

  • Weill Cornell Medical College, Cornell University