Norton, Larry

Selected publications

MYBL1 rearrangements and MYB amplification in breast adenoid cystic carcinomas lacking the MYB–NFIB fusion gene. Journal of Pathology. 2018 Academic Article GET IT
3rd ESO-ESMO International Consensus Guidelines for Advanced Breast Cancer (ABC 3). Annals of Oncology. 2017 Academic Article GET IT
Times cited: 57
Breast carcinoma with an Oncotype Dx recurrence score <18: Rate of distant metastases in a large series with clinical follow-up. Cancer. 2017 Academic Article GET IT
Times cited: 4
Genetic analysis of microglandular adenosis and acinic cell carcinomas of the breast provides evidence for the existence of a low-grade triple-negative breast neoplasia family. Modern Pathology. 2017 Academic Article GET IT
Times cited: 5
Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 2017 Academic Article GET IT
Sleep problems in breast cancer survivors 1–10 years posttreatment. Palliative and Supportive Care. 2017 Academic Article GET IT
Times cited: 1
Corrigendum to “3rd ESO-ESMO international consensus guidelines for advanced breast cancer (ABC 3)” [Breast 31 (February 2017) 244–259] (S0960977616301837)(10.1016/j.breast.2016.10.001). Breast. 2017 Article GET IT
Pathologic complete response with neoadjuvant doxorubicin and cyclophosphamide followed by paclitaxel with trastuzumab and pertuzumab in patients with HER2-positive early stage breast cancer: A single center experience. Oncologist. 2017 Academic Article GET IT
Times cited: 2
3rd ESO–ESMO international consensus guidelines for Advanced Breast Cancer (ABC 3). Breast. 2017 Review GET IT
Times cited: 35
A Rare Case of S310F Somatic ERBB2 Mutation in a HER2-Nonamplified Breast Cancer. Clinical Breast Cancer. 2017 Academic Article GET IT
Dealing with the tyranny of certainty in the (medical) digital age. Psycho-Oncology. 2017 Article GET IT
The genetic landscape of breast carcinomas with neuroendocrine differentiation. Journal of Pathology. 2017 Academic Article GET IT
Times cited: 2
A pilot study of preoperative single-dose ipilimumab and/or cryoablation in women with early-stage breast cancer with comprehensive immune profiling. Clinical Cancer Research. 2016 Academic Article GET IT
Times cited: 17
A recurrent ERCC3 truncating mutation confers moderate risk for breast cancer. Cancer Discovery. 2016 Academic Article GET IT
Times cited: 8
Deep sequencing of T-cell receptor DNA as a biomarker of clonally expanded TILs in breast cancer after immunotherapy. Cancer Immunology Research. 2016 Academic Article GET IT
Times cited: 8
The genomic landscape of male breast cancers. Clinical Cancer Research. 2016 Academic Article GET IT
Times cited: 25
Biomarkers That Predict Sensitivity to Heat Shock Protein 90 Inhibitors. Clinical Breast Cancer. 2016 Academic Article GET IT
Times cited: 1
Prognostic Impact of 21-Gene Recurrence Score in Patients With Stage IV Breast Cancer: TBCRC 013. Journal of Clinical Oncology. 2016 Academic Article GET IT
Times cited: 14
Weekly paclitaxel with trastuzumab and pertuzumab in patients with HER2-overexpressing metastatic breast cancer: overall survival and updated progression-free survival results from a phase II study. Breast Cancer Research and Treatment. 2016 Academic Article GET IT
Times cited: 4
Cold thermal injury from cold caps used for the prevention of chemotherapy-induced alopecia. Breast Cancer Research and Treatment. 2016 Academic Article GET IT
Times cited: 5
Genetic alterations of triple negative breast cancer by targeted next-generation sequencing and correlation with tumor morphology. Modern Pathology. 2016 Academic Article GET IT
Times cited: 14
A Pilot Study of Dose-Dense Paclitaxel with Trastuzumab and Lapatinib for Node-negative HER2-Overexpressed Breast Cancer. Clinical Breast Cancer. 2016 Academic Article GET IT
Cardiac surveillance guidelines for trastuzumab-containing therapy in early-stage breast cancer: Getting to the heart of the matter. Journal of Clinical Oncology. 2016 Review GET IT
Times cited: 13
JAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitors. Science Signaling. 2016 Academic Article GET IT
Times cited: 17
Genome sequencing of multiple primary tumors reveals a novel PALB2 variant. Journal of Clinical Oncology. 2016 Academic Article GET IT
Times cited: 2
Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss. Genes and Development. 2016 Academic Article GET IT
Times cited: 79
Massively parallel sequencing of phyllodes tumours of the breast reveals actionable mutations, and TERT promoter hotspot mutations and TERT gene amplification as likely drivers of progression. Journal of Pathology. 2016 Academic Article GET IT
Times cited: 16
Adjuvant bisphosphonate treatment in early breast cancer: Meta-analyses of individual patient data from randomised trials. Lancet. 2015 Academic Article GET IT
Times cited: 141
Aromatase inhibitors versus tamoxifen in early breast cancer: Patient-level meta-analysis of the randomised trials. Lancet. 2015 Academic Article GET IT
Times cited: 194
Genomic landscape of adenoid cystic carcinoma of the breast. Journal of Pathology. 2015 Academic Article GET IT
Times cited: 34
The repertoire of somatic genetic alterations of acinic cell carcinomas of the breast: An exploratory, hypothesis-generating study. Journal of Pathology. 2015 Academic Article GET IT
Times cited: 19
Disabling of the erbB Pathway Followed by IFN-γ Modifies Phenotype and Enhances Genotoxic Eradication of Breast Tumors. Cell Reports. 2015 Academic Article GET IT
Times cited: 4
Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification. Genome Biology. 2015 Academic Article GET IT
Times cited: 38
Current management of lesions associated with an increased risk of breast cancer. Nature Reviews Clinical Oncology. 2015 Review GET IT
Times cited: 22
Phase II study of paclitaxel given once per week along with trastuzumab and pertuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer. Journal of Clinical Oncology. 2015 Academic Article GET IT
Times cited: 31
Metastatic breast carcinomas display genomic and transcriptomic heterogeneity. Modern Pathology. 2015 Academic Article GET IT
Times cited: 15
Recommendations for standardized pathological characterization of residual disease for neoadjuvant clinical trials of breast cancer by the BIG-NABCG collaboration. Annals of Oncology. 2015 Review GET IT
Times cited: 43
Response to dual HER2 blockade in a patient with HER3-mutant metastatic breast cancer. Annals of Oncology. 2015 Academic Article GET IT
Times cited: 9
Serum metabolomic profiles evaluated after surgery may identify patients with oestrogen receptor negative early breast cancer at increased risk of disease recurrence. Results from a retrospective study. Molecular Oncology. 2015 Academic Article GET IT
Times cited: 24
Mesothelin expression in triple negative breast carcinomas correlates significantly with basal-like phenotype, distant metastases and decreased survival. PLoS ONE. 2014 Academic Article GET IT
Times cited: 15
Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands. Nature Genetics. 2014 Academic Article GET IT
Times cited: 65
ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2)†. Annals of Oncology. 2014 Academic Article GET IT
Times cited: 199
Comparison of doxorubicin and cyclophosphamide versus single-agent paclitaxel as adjuvant therapy for breast cancer in women with 0 to 3 positive axillary nodes: CALGB 40101 (alliance). Journal of Clinical Oncology. 2014 Academic Article GET IT
Times cited: 32
Slug promotes survival during metastasis through suppression of puma-mediated apoptosis. Cancer Research. 2014 Academic Article GET IT
Times cited: 17
N-cadherin/FGFR promotes metastasis through epithelial-to-mesenchymal transition and stem/progenitor cell-like properties. Oncogene. 2014 Academic Article GET IT
Times cited: 52
Advances in managing breast cancer: A clinical update. F1000Prime Reports. 2014 Review GET IT
Times cited: 7
Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations. Genome Biology. 2014 Academic Article GET IT
Times cited: 48
Cancer log-kill revisited. American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting. 2014 Review GET IT
Times cited: 4
Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: A proof-of-principle. Annals of Oncology. 2014 Academic Article GET IT
Times cited: 116
ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2). Breast. 2014 Conference Paper GET IT
Times cited: 140
Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: Meta-analysis of individual patient data for 8135 women in 22 randomised trials. Lancet. 2014 Academic Article GET IT
Times cited: 501
The effects of soy supplementation on gene expression in breast cancer: a randomized placebo-controlled study. Journal of the National Cancer Institute. 2014 Academic Article GET IT
Times cited: 24
TGF-β-Id1 signaling opposes twist1 and promotes metastatic colonization via a mesenchymal-to-epithelial transition. Cell Reports. 2013 Academic Article GET IT
Times cited: 80
Long-term cardiac safety and outcomes of dose-dense doxorubicin and cyclophosphamide followed by paclitaxel and trastuzumab with and without lapatinib in patients with early breast cancer. Cancer. 2013 Academic Article GET IT
Times cited: 10
Acquired resistance to crizotinib from a mutation in CD74-ROS1. New England Journal of Medicine. 2013 Article GET IT
Times cited: 4
Association between Bone Mineral Density and Incidence of Breast Cancer. PLoS ONE. 2013 Academic Article GET IT
Times cited: 11
Epoetin alfa: To give or not to give. Journal of the National Cancer Institute. 2013 Article GET IT
The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis. Neoplasia. 2013 Academic Article GET IT
Times cited: 120
P21CIP1 mediates reciprocal switching between proliferation and invasion during metastasis. Oncogene. 2013 Academic Article GET IT
Times cited: 8
Living with metastatic breast cancer: A qualitative analysis of physical, psychological, and social sequelae. Breast Journal. 2013 Academic Article GET IT
Times cited: 20
Spreaders and sponges define metastasis in lung cancer: A markov chain monte carlo mathematical model. Cancer Research. 2013 Academic Article GET IT
Times cited: 30
Randomized phase II trial of weekly vs. every 2 weeks vs. every 3 weeks nanoparticle albumin-bound paclitaxel with bevacizumab as first-line chemotherapy for metastatic breast cancer. Clinical Breast Cancer. 2013 Academic Article
Times cited: 18
Frequent mutational activation of the PI3K-AKT pathway in trastuzumab-resistant breast cancer. Clinical Cancer Research. 2012 Academic Article GET IT
Times cited: 86
Reply to S. Mahesh. Journal of Clinical Oncology. 2012 Information Resource GET IT
Translating mathematical modeling of tumor growth patterns into novel therapeutic approaches for breast cancer. Journal of Mammary Gland Biology and Neoplasia. 2012 Review GET IT
Times cited: 9
Six cycles of doxorubicin and cyclophosphamide or paclitaxel are not superior to four cycles as adjuvant chemotherapy for breast cancer in women with zero to three positive axillary nodes: Cancer and leukemia group B 40101. Journal of Clinical Oncology. 2012 Academic Article GET IT
Times cited: 47
DNA mismatch repair deficiency in breast carcinoma: a pilot study of triple-negative and non-triple-negative tumors. American Journal of Surgical Pathology. 2012 Academic Article GET IT
Times cited: 4
Can we really use retrospective subset analyses and surveillance, epidemiology, and end results data to drive clinical practice?. Journal of Clinical Oncology. 2012 Article GET IT
Times cited: 3
Rare de novo germline copy-number variation in testicular cancer. American Journal of Human Genetics. 2012 Academic Article GET IT
Times cited: 12
Id4 protein is highly expressed in triple-negative breast carcinomas: Possible implications for BRCA1 downregulation. Breast Cancer Research and Treatment. 2012 Academic Article GET IT
Times cited: 21
A CXCL1 paracrine network links cancer chemoresistance and metastasis. Cell. 2012 Academic Article GET IT
Times cited: 362
Choosing the best trastuzumab- based adjuvant chemotherapy regimen: Should we abandon anthracyclines?. Journal of Clinical Oncology. 2012 Article GET IT
Times cited: 30
1st International consensus guidelines for advanced breast cancer (ABC 1). Breast. 2012 Conference Paper GET IT
Times cited: 194
Self-seeding in cancer. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer. 2012 Review GET IT
Times cited: 19
Potent induction of tumor immunity by combining tumor cryoablation with anti-CTLA-4 therapy. Cancer Research. 2012 Academic Article GET IT
Times cited: 96
Phase II trial of a novel capecitabine dosing schedule in combination with lapatinib for the treatment of patients with HER2-positive metastatic breast cancer. Breast Cancer Research and Treatment. 2012 Academic Article GET IT
Times cited: 13
Randomised trial of expressive writing for distressed metastatic breast cancer patients. Psychology and Health. 2012 Academic Article GET IT
Times cited: 25
Adjuvant trastuzumab with chemotherapy is effective in women with small, node-negative, HER2-positive breast cancer. Cancer. 2011 Academic Article GET IT
Times cited: 55
A phase I study of dasatinib and weekly paclitaxel for metastatic breast cancer. Annals of Oncology. 2011 Academic Article GET IT
Times cited: 31
Phase III double-blind, placebo-controlled, prospective randomized trial of adjuvant tamoxifen vs. tamoxifen and fenretinide in postmenopausal women with positive receptors (EB193): An intergroup trial coordinated by the Eastern Cooperative Oncology Group. Medical Oncology. 2011 Academic Article GET IT
Times cited: 5
Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: Meta-analysis of individual patient data for 10 801 women in 17 randomised trials. Lancet. 2011 Academic Article GET IT
Times cited: 1174
Phase 2 trial of a novel capecitabine dosing schedule in combination with bevacizumab for patients with metastatic breast cancer. Cancer. 2011 Academic Article GET IT
Times cited: 13
Tumor entrained neutrophils inhibit seeding in the premetastatic lung. Cancer Cell. 2011 Academic Article GET IT
Times cited: 220
HSP90 inhibition is effective in breast cancer: A phase II trial of tanespimycin (17-AAG) plus trastuzumab in patients with HER2-positive metastatic breast cancer progressing on trastuzumab. Clinical Cancer Research. 2011 Academic Article GET IT
Times cited: 260
p53 expression in node-positive breast cancer patients: Results from the cancer and leukemia group B 9344 trial (159905). Clinical Cancer Research. 2011 Academic Article GET IT
Times cited: 18
Breast cancer tumor size, nodal status, and prognosis: Biology trumps anatomy. Journal of Clinical Oncology. 2011 Article GET IT
Times cited: 22
Tumor self-seeding in breast cancer. Clinical Advances in Hematology and Oncology. 2011 Academic Article GET IT
Times cited: 1
Clinical implications of cancer self-seeding. Nature Reviews Clinical Oncology. 2011 Review GET IT
Times cited: 145
A feasibility study of bevacizumab plus dose-dense doxorubicin- cyclophosphamide (AC) followed by nanoparticle albumin-bound paclitaxel in early-stage breast cancer. Clinical Cancer Research. 2011 Academic Article GET IT
Times cited: 23
Troponin I and C-reactive protein are commonly detected in patients with breast cancer treated with dose-dense chemotherapy incorporating trastuzumab and lapatinib. Clinical Cancer Research. 2011 Academic Article GET IT
Times cited: 81
Breast cancer methylomes establish an epigenomic foundation for metastasis. Science Translational Medicine. 2011 Academic Article GET IT
Times cited: 155
MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer. Genes and Development. 2011 Academic Article GET IT
Times cited: 140
Cancer stem cells, EMT, and seeding: A rose is a rose is a rose?. ONCOLOGY. 2011 Comment
Cancer stem cells, EMT, and seeding: a rose is a rose is a rose?. ONCOLOGY. 2011 Comment
Times cited: 4
Intracystic papillary carcinoma of the breast: An in situ or invasive tumor? results of immunohistochemical analysis and clinical follow-up. American Journal of Surgical Pathology. 2011 Academic Article GET IT
Times cited: 43
Phase II trial of saracatinib (AZD0530), an oral SRC-inhibitor for the treatment of patients with hormone receptor-negative metastatic breast cancer. Clinical Breast Cancer. 2011 Academic Article GET IT
Times cited: 64
Optimizing chemotherapy dose and schedule by Norton-Simon mathematical modeling. Breast Disease. 2010 Academic Article GET IT
Times cited: 15
Capecitabine dosing is not yet optimized for breast cancer. Annals of Oncology. 2010 Article GET IT
Dose-dense doxorubicin and cyclophosphamide followed by weekly paclitaxel with trastuzumab and lapatinib in HER2/neu-overexpressed/amplified breast cancer is not feasible because of excessive diarrhea. Journal of Clinical Oncology. 2010 Academic Article GET IT
Times cited: 32
Dose-dense chemotherapy for breast cancer: what does the future hold?. Future Oncology. 2010 Review GET IT
Times cited: 8
Germline BRCA mutations denote a clinicopathologic subset of prostate cancer. Clinical Cancer Research. 2010 Academic Article GET IT
Times cited: 107
Impact of High-Dose Chemotherapy on the Ability to Deliver Subsequent Local-Regional Radiotherapy for Breast Cancer: Analysis of Cancer and Leukemia Group B Protocol 9082. International Journal of Radiation Oncology Biology Physics. 2010 Academic Article GET IT
Times cited: 3
Feasibility trial of letrozole in combination with bevacizumab in patients with metastatic breast cancer. Journal of Clinical Oncology. 2010 Academic Article GET IT
Times cited: 38
Dose dense cyclophosphamide, methotrexate, fluorouracil is feasible at 14-day intervals: A pilot study of every-14-day dosing as adjuvant therapy for breast cancer. Clinical Breast Cancer. 2010 Academic Article GET IT
Times cited: 3
Inhibitors of HSP90 block p95-HER2 signaling in Trastuzumab-resistant tumors and suppress their growth. Oncogene. 2010 Academic Article GET IT
Times cited: 80
Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast. Journal of the National Cancer Institute - Monographs. 2010 Review GET IT
Times cited: 269
Tumor Self-Seeding by Circulating Cancer Cells. Cell. 2009 Academic Article GET IT
Times cited: 640
Dose-dense adjuvant doxorubicin and cyclophosphamide is not associated with frequent short-term changes in left ventricular ejection fraction. Journal of Clinical Oncology. 2009 Academic Article GET IT
Times cited: 21
Role of anthracyclines in the treatment of early breast cancer. Journal of Clinical Oncology. 2009 Review GET IT
Times cited: 60
The 6q22.33 locus and breast cancer susceptibility. Cancer Epidemiology Biomarkers and Prevention. 2009 Review GET IT
Times cited: 21
Latent Bone Metastasis in Breast Cancer Tied to Src-Dependent Survival Signals. Cancer Cell. 2009 Academic Article GET IT
Times cited: 355
A pilot study of dose-dense adjuvant paclitaxel without growth factor support for women with early breast carcinoma. Breast Cancer Research and Treatment. 2009 Academic Article GET IT
Times cited: 9
Adjuvant chemotherapy in older women with early-stage breast cancer. New England Journal of Medicine. 2009 Academic Article GET IT
Times cited: 321
Fifteen-year median follow-up results after neoadjuvant doxorubicin, followed by mastectomy, followed by adjuvant cyclophosphamide, methotrexate, and fluorouracil (CMF) followed by radiation for stage III breast cancer: A phase II trial (CALGB 8944). Breast Cancer Research and Treatment. 2009 Academic Article GET IT
Times cited: 10
A phase II trial of erlotinib in combination with bevacizumab in patients with metastatic breast cancer. Clinical Cancer Research. 2008 Academic Article GET IT
Times cited: 78
Prolonged dose-dense epirubicin and cyclophosphamide followed by paclitaxel in breast cancer is feasible. Clinical Breast Cancer. 2008 Academic Article GET IT
Times cited: 5
Racial differences in clinical outcomes from metastatic breast cancer: A pooled analysis of CALGB 9342 and 9840 - Cancer and leukemia group B. Journal of Clinical Oncology. 2008 Academic Article GET IT
Times cited: 22
Dose-dense chemotherapy with trastuzumab is an appropriate option. Journal of Clinical Oncology. 2008 Article GET IT
Times cited: 1
Influence of activation state of ErbB-2 (HER-2) on response to adjuvant cyclophosphamide, doxorubicin, and fluorouracil for stage II, node-positive breast cancer: Study 8541 from the cancer and leukemia group B. Journal of Clinical Oncology. 2008 Academic Article GET IT
Times cited: 5
Late extended adjuvant treatment with letrozole improves outcome in women with early-stage breast cancer who complete 5 years of tamoxifen. Journal of Clinical Oncology. 2008 Academic Article GET IT
Times cited: 145
Occult axillary node metastases in breast cancer are prognostically significant: Results in 368 node-negative patients with 20-year follow-up. Journal of Clinical Oncology. 2008 Academic Article GET IT
Times cited: 119
Phase I study of a novel capecitabine schedule based on the Norton-Simon mathematical model in patients with metastatic breast cancer. Journal of Clinical Oncology. 2008 Academic Article GET IT
Times cited: 52
Randomized phase III trial of weekly compared with every-3-weeks paclitaxel for metastatic breast cancer, with trastuzumab for all HER-2 overexpressors and random assignment to trastuzumab or not in HER-2 nonoverexpressors: Final results of cancer and leukemia group B protocol 9840. Journal of Clinical Oncology. 2008 Academic Article GET IT
Times cited: 412
Pharmacokinetics and tolerability of exemestane in combination with raloxifene in postmenopausal women with a history of breast cancer. Breast Cancer Research and Treatment. 2008 Academic Article GET IT
Times cited: 21
Dose-escalation of filgrastim does not improve efficacy: Clinical tolerability and long-term follow-up on CALGB study 9141 adjuvant chemotherapy for node-positive breast cancer patients using dose-intensified doxorubicin plus cyclophosphamide followed by paclitaxel. Cancer Treatment Reviews. 2008 Academic Article GET IT
Times cited: 10
Intent-to-treat analysis of the placebo-controlled trial of letrozole for extended adjuvant therapy in early breast cancer: NCIC CTG MA.17. Annals of Oncology. 2008 Academic Article GET IT
Times cited: 48
Changing indications for surgery in patients with stage IV breast cancer: A current perspective. Cancer. 2008 Academic Article GET IT
Times cited: 15
Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33. Proceedings of the National Academy of Sciences of the United States of America. 2008 Academic Article GET IT
Times cited: 238
Risk-reducing salpingo-oophorectomy for the prevention of BRCA1- and BRCA2-associated breast and gynecologic cancer: A multicenter, prospective study. Journal of Clinical Oncology. 2008 Academic Article GET IT
Times cited: 349
The safety of dose-dense doxorubicin and cyclophosphamide followed by paclitaxel with trastuzumab in HER-2/neu overexpressed/amplified breast cancer. Journal of Clinical Oncology. 2008 Academic Article GET IT
Times cited: 38
Analysis of genetic variation in Ashkenazi Jews by high density SNP genotyping. BMC Genetics. 2008 Academic Article GET IT
Times cited: 25
SNX2112, a synthetic heat shock protein 90 inhibitor, has potent antitumor activity against HER kinase - Dependent cancers. Clinical Cancer Research. 2008 Academic Article GET IT
Times cited: 141
Cancer stem cells, self-seeding, and decremented exponential growth: Theoretical and clinical implications. Breast Disease. 2007 Academic Article GET IT
Times cited: 27
Combination of trastuzumab and tanespimycin (17-AAG, KOS-953) is safe and active in trastuzumab-refractory HER-2-overexpressing breast cancer: A phase I dose-escalation study. Journal of Clinical Oncology. 2007 Academic Article GET IT
Times cited: 278
Tumor dormancy: Separating observations from experimental science. Nature Clinical Practice Oncology. 2007 Article GET IT
Times cited: 1
American society of clinical oncology 2007 update of recommendations for the use of tumor markers in breast cancer. Journal of Clinical Oncology. 2007 Review GET IT
Times cited: 1533
American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer. Journal of Oncology Practice. 2007 Report GET IT
Antibody and CD8+ T cell responses against HER2/neu required for tumor eradication after DNA immunization with a Flt-3 ligand fusion vaccine. Clinical Cancer Research. 2007 Academic Article GET IT
Times cited: 22
HER2 and response to paclitaxel in node-positive breast cancer. New England Journal of Medicine. 2007 Academic Article GET IT
Times cited: 444
Heterogenic loss of the wild-type BRCA allele in human breast tumorigenesis. Annals of Surgical Oncology. 2007 Academic Article GET IT
Times cited: 63
Toxicity of older and younger patients treated with adjuvant chemotherapy for node-positive breast cancer: The Cancer and Leukemia Group B experience. Journal of Clinical Oncology. 2007 Academic Article GET IT
Times cited: 164
Discussion. Clinical Trials. 2007 Comment GET IT
Times cited: 1
Efficacy of letrozole extended adjuvant therapy according to estrogen receptor and progesterone receptor status of the primary tumor: National Cancer Institute of Canada Clinical Trials Group MA.17. Journal of Clinical Oncology. 2007 Academic Article GET IT
Times cited: 92
Immunization of high-risk breast cancer patients with clustered sTn-KLH conjugate plus the immunologic adjuvant QS-21. Clinical Cancer Research. 2007 Academic Article GET IT
Times cited: 65
From the guest editors. Cancer Journal. 2007 Editorial Article GET IT
Keeping faith with trial volunteers: Commentary. Nature. 2007 Article GET IT
Times cited: 14
Increased dose density is feasible: A pilot study of adjuvant epirubicin and cyclophosphamide followed by paclitaxel, at 10- or 11-day intervals with filgrastim support in women with breast cancer. Clinical Cancer Research. 2007 Academic Article GET IT
Times cited: 9
Interleukin-6, multidrug resistance protein-1 expression and response to paclitaxel in women with metastatic breast cancer: Results of cancer and leukemia group B trial 159806. Breast Cancer Research and Treatment. 2006 Academic Article GET IT
Times cited: 17
Novel patterns of genome rearrangement and their association with survival in breast cancer. Genome Research. 2006 Academic Article GET IT
Times cited: 232
Role of modeling in pharmacotherapeutics. 2006 Chapter GET IT
Times cited: 1
Nasal septum perforation in a bevacizumab-treated patient with metastatic breast cancer. Oncologist. 2006 Academic Article GET IT
Times cited: 41
Pharmacokinetics and toxicity of weekly docetaxel in older patients. Clinical Cancer Research. 2006 Academic Article GET IT
Times cited: 58
Duration of letrozole treatment and outcomes in the placebo-controlled NCIC CTG MA.17 extended adjuvant therapy trial. Breast Cancer Research and Treatment. 2006 Academic Article GET IT
Times cited: 77
Effect of adjuvant breast cancer chemotherapy on cognitive function from the older patient's perspective. Breast Cancer Research and Treatment. 2006 Academic Article GET IT
Times cited: 60
Is cancer a disease of self-seeding?. Nature Medicine. 2006 Academic Article GET IT
Times cited: 212
The Norton - Simon hypothesis: Designing more effective and less toxic chemotherapeutic regimens. Nature Clinical Practice Oncology. 2006 Review GET IT
Times cited: 94
Estrogen-receptor status and outcomes of modern chemotherapy for patients with node-positive breast cancer. JAMA - Journal of the American Medical Association. 2006 Academic Article GET IT
Times cited: 517
A phase I study of cetuximab in combination with paclitaxel in patients with advanced-stage breast cancer. Clinical Breast Cancer. 2006 Academic Article
Times cited: 72
Expression of osteoprotegerin (OPG), TNF related apoptosis inducing ligand (TRAIL), and receptor activator of nuclear factor κB ligand (RANKL) in human breast tumours. Journal of Clinical Pathology. 2006 Academic Article GET IT
Times cited: 58
Localization of breast cancer susceptibility loci by genome-wide SNP linkage disequilibrium mapping. Genetic Epidemiology. 2006 Academic Article GET IT
Times cited: 14
Use of dose-dense chemotherapy in the management of breast cancer. Clinical Advances in Hematology and Oncology. 2006 Review GET IT
Times cited: 7
Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: An overview of the randomised trials. Lancet. 2005 Report GET IT
Times cited: 2980
Comparison of HER2 status by fluorescence in situ hybridization and immunohistochemistry to predict benefit from dose escalation of adjuvant doxorubicin-based therapy in node-positive breast cancer patients. Journal of Clinical Oncology. 2005 Academic Article GET IT
Times cited: 90
Effect of creatinine clearance on patterns of toxicity in older patients receiving adjuvant chemotherapy for breast cancer. Drugs & aging.. 2005 Academic Article GET IT
Times cited: 21
Prospective, randomized comparison of high-dose chemotherapy with stem-cell support versus intermediate-dose chemotherapy after surgery and adjuvant chemotherapy in women with high-risk primary breast cancer: A report of CALGB 9082, SWOG 9114, and NCIC MA-13. Journal of Clinical Oncology. 2005 Academic Article GET IT
Times cited: 88
Systemic Treatment for Stage I and Stage II Breast Cancer. 2005 Chapter GET IT
Expression of WT1, CA 125, and GCDFP-15 as useful markers in the differential diagnosis of primary ovarian carcinomas versus metastatic breast cancer to the ovary. American Journal of Surgical Pathology. 2005 Academic Article GET IT
Times cited: 91
Phosphorylated/activated HER2 as a marker of clinical resistance to single agent taxane chemotherapy for metastatic breast cancer. Cancer Investigation. 2005 Academic Article GET IT
Times cited: 34
Incidence of chemotherapy-induced, long-term amenorrhea in patients with breast carcinoma age 40 years and younger after adjuvant anthracycline and taxane. Cancer. 2005 Academic Article GET IT
Times cited: 133
Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: Updated findings from NCIC CTG MA.17. Journal of the National Cancer Institute. 2005 Academic Article GET IT
Times cited: 858
Radiation pneumonitis in breast cancer patients treated with taxanes: Does sequential radiation therapy lower the risk?. Breast Journal. 2005 Academic Article GET IT
Times cited: 3
Risk of ovarian cancer in BRCA1 and BRCA2 mutation-negative hereditary breast cancer families. Journal of the National Cancer Institute. 2005 Academic Article GET IT
Times cited: 65
Change in cycle 1 to cycle 2 haematological counts predicts toxicity in older patients with breast cancer receiving adjuvant chemotherapy. Drugs & aging.. 2005 Report GET IT
Times cited: 9
Patterns of toxicity in older patients with breast cancer receiving adjuvant chemotherapy. Breast Cancer Research and Treatment. 2005 Academic Article GET IT
Times cited: 38
Conceptual and practical implications of breast tissue geometry: Toward a more effective, less toxic therapy. Oncologist. 2005 Academic Article GET IT
Times cited: 116
Adjuvant chemotherapy in older and younger women with lymph node-positive breast cancer. JAMA - Journal of the American Medical Association. 2005 Academic Article GET IT
Times cited: 276
A phase II trial of imatinib mesylate monotherapy in patients with metastatic breast cancer. Breast Cancer Research and Treatment. 2005 Academic Article GET IT
Times cited: 66
Dose-dense adjuvant chemotherapy for primary breast cancer. Breast Cancer Research. 2005 Academic Article GET IT
Times cited: 27
Serum HER2 extracellular domain in metastatic breast cancer patients treated with weekly trastuzumab and paclitaxel: Association with HER2 status by immunohistochemistry and fluorescence in situ hybridization and with response rate. Annals of Oncology. 2005 Academic Article GET IT
Times cited: 93
A phase II trial of gemcitabine in patients with metastatic breast cancer previously treated with an anthracycline and taxane. Clinical Breast Cancer. 2005 Academic Article
Times cited: 49
Appropriateness of breast-conserving treatment of breast carcinoma in women with germline mutations in BRCA1 or BRCA2: A clinic-based series. Cancer. 2005 Academic Article GET IT
Times cited: 102
Effect of addition of adjuvant paclitaxel on radiotherapy delivery and locoregional control of node-positive breast cancer: Cancer and Leukemia Group B 9344. Journal of Clinical Oncology. 2005 Academic Article GET IT
Times cited: 70
A tool for predicting breast carcinoma mortality in women who do not receive adjuvant therapy. Cancer. 2004 Academic Article GET IT
Times cited: 30
Current status of dose-dense chemotherapy for breast cancer. Breast Diseases. 2004 Report
Failure of higher-dose paclitaxel to improve outcome in patients with metastatic breast cancer: Cancer and leukemia group B trial 9342. Journal of Clinical Oncology. 2004 Academic Article GET IT
Times cited: 213
The NHL-15 protocol for aggressive non-Hodgkin's lymphomas: A sequential dose-dense, dose-intense regimen of doxorubicin, vincristine and high-dose cyclophosphamide. Annals of Oncology. 2004 Academic Article GET IT
Times cited: 12
Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer. New England Journal of Medicine. 2004 Academic Article GET IT
Times cited: 632
Cytokeratin-positive cells in sentinel lymph nodes in breast cancer are not random events: Experience in patients undergoing prophylactic mastectomy. Cancer. 2004 Academic Article GET IT
Times cited: 34
Phase II study of feasibility of dose-dense FEC followed by alternating weekly taxanes in high-risk, four or more node-positive breast cancer. Clinical Cancer Research. 2004 Academic Article GET IT
Times cited: 26
Phase II study of celecoxib and trastuzumab in metastatic breast cancer patients who have progressed after prior trastuzumab-based treatments. Clinical Cancer Research. 2004 Academic Article GET IT
Times cited: 51
Subcutaneously administered recombinant human interleukin-2 and interferon alfa-2a for advanced breast cancer: A Phase II study of the Cancer and Leukemia Group B (CALGB 9041). Investigational New Drugs. 2004 Academic Article GET IT
Times cited: 5
In reply. Journal of Clinical Oncology. 2003 Information Resource GET IT
Times cited: 2
A Randomized Trial of Letrozole in Postmenopausal Women after Five Years of Tamoxifen Therapy for Early-Stage Breast Cancer. New England Journal of Medicine. 2003 Academic Article GET IT
Times cited: 1486
A combined analysis of outcome following breast cancer: Differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment. Breast Cancer Research. 2003 Academic Article GET IT
Times cited: 206
Shared genetic susceptibility to breast cancer, brain tumors, and Fanconi anemia. Journal of the National Cancer Institute. 2003 Academic Article GET IT
Times cited: 122
Representational oligonucleotide microarray analysis: A high-resolution method to detect genome copy number variation. Genome Research. 2003 Academic Article GET IT
Times cited: 311
Long-term adjustment of survivors of early-stage breast carcinoma, 20 years after adjuvant chemotherapy. Cancer. 2003 Academic Article GET IT
Times cited: 213
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Utility of thyroid aspiration biopsy. Surgery. 1982 Academic Article GET IT
Times cited: 18
Diffuse malignant mesothelioma. Prospective evaluation of 69 patients. Annals of Internal Medicine. 1982 Academic Article GET IT
Times cited: 265
A lump in the breast: assessment and options for local treatment. Arizona Medicine. 1982 Academic Article GET IT
Needle aspiration biopsy of thyroid nodules. Arizona Medicine. 1981 Academic Article GET IT
Non-monotonic dose-response to chemotherapy of murine B-16 melanoma (MM). Proceedings of the American Association for Cancer Research. 1981 Academic Article
Times cited: 2
Nodular histiocytic lymphoma: An aggressive nodular lymphoma with potential for prolonged disease-free survival. Blood. 1980 Academic Article GET IT
Times cited: 38
Outcome of Operations for Upper Gastrointestinal Tract Bleeding: An Update. Archives of Surgery. 1980 Academic Article GET IT
Times cited: 9
Selective Intra-arterial Vasopressin Infusion for Upper Gastrointestinal Tract Hemorrhage: A Controlled Trial. Archives of Surgery. 1980 Academic Article GET IT
Times cited: 58
Small bowel neomucosa. Journal of Surgical Research. 1980 Academic Article GET IT
Times cited: 37
Caroli's disease: a surgical challenge. American Surgeon. 1979 Academic Article GET IT
Times cited: 3
Invited commentary. World Journal of Surgery. 1979 Academic Article GET IT
Accuracy of techniques to detect intraperitoneal abscess. Obstetrical and Gynecological Survey. 1979 Academic Article
Massive cecal dilation: Pseudoobstruction versus cecal volvulus?. American journal of surgery. 1979 Academic Article GET IT
Times cited: 24
Treatment of advanced breast cancer with a novel cyclophosphamide (C), methotrexate (M), 5-fluorouracil (F), vincristine (V) and prednisone (P) regimen. Proceedings of the American Association for Cancer Research. 1979 Academic Article
Accuracy of techniques to detect intraperitoneal abscess. Surgery. 1978 Academic Article GET IT
Times cited: 24
Lack of therapeutic synergism between vincristine and methotrexate in L1210 murine leukemia in vivo. Cancer Treatment Reports. 1978 Academic Article GET IT
Times cited: 13
Gastric ulcers following vagotomy in piglets. World Journal of Surgery. 1978 Academic Article GET IT
Times cited: 1
A new method for screening anti-cancer agents on solid tumors. Proceedings of the American Association for Cancer Research. 1978 Academic Article
Condyloma: A New Epidemic. Archives of Surgery. 1978 Academic Article GET IT
Times cited: 6
Depression of Cell-Mediated Immunity in Diabetes. Archives of Surgery. 1978 Academic Article GET IT
Times cited: 37
Immunologic studies of canine lymphosarcoma: Mixed leukocyte reactivity following chemotherapy. Clinical Immunology and Immunopathology. 1978 Academic Article GET IT
Times cited: 3
Preventing bile reflux by intussusception gastroduodenostomy. Journal of Surgical Research. 1978 Academic Article GET IT
Times cited: 1
Statistical considerations in determination of ventricular volume from echocardiographic and angiographic data. American Journal of Cardiology. 1978 Information Resource GET IT
The continuing challenge of duodenal injuries. Journal of Trauma - Injury, Infection and Critical Care. 1978 Academic Article GET IT
Times cited: 35
The treatment of combination chemotherapy‐resistant Hodgkin disease with single‐agent vinblastine. American Journal of Hematology. 1978 Academic Article GET IT
Times cited: 6
Combination chemotherapy in non-Hodgkin's lymphoma: results of long-term followup. Cancer Treatment Reports. 1977 Academic Article GET IT
Times cited: 126
Hepatic support with hepatocyte suspensions in a permeable membrane dialyzer. Surgery. 1977 Academic Article GET IT
Times cited: 46
Migration of transfused granulocytes in leukopenic dogs. Blood. 1977 Academic Article GET IT
Times cited: 18
Multiple organ failure. Surgery Gynecology and Obstetrics. 1977 Academic Article GET IT
Times cited: 240
Tumor size, sensitivity to therapy, and design of treatment schedules. Cancer Treatment Reports. 1977 Academic Article GET IT
Times cited: 375
Clinical indications and accuracy of gray scale ultrasonography in the patient with suspected biliary tract disease. American journal of surgery. 1977 Academic Article GET IT
Times cited: 18
Effect of prior radiotherapy on tolerance and response to chemotherapy in non‐hodgkin's lymphoma. American Journal of Hematology. 1977 Academic Article GET IT
Times cited: 4
Growth curve of an experimental solid tumor following radiotherapy. Journal of the National Cancer Institute. 1977 Academic Article GET IT
Times cited: 84
Depressed cellular immunity in diabetics. Surgical Forum. 1976 Academic Article GET IT
Times cited: 3
Hepatocyte perfusion within a centrifuge. Surgery Gynecology and Obstetrics. 1976 Academic Article GET IT
Times cited: 27
Predicting the course of Gompertzian growth. Nature. 1976 Academic Article GET IT
Times cited: 194
Community experience with small bowel bypass for morbid obesity. American journal of surgery. 1976 Academic Article GET IT
Times cited: 4
Morbidity of colostomy closure. American journal of surgery. 1976 Academic Article GET IT
Times cited: 57
Current management of upper gastrointestinal bleeding. Annals of Surgery. 1975 Academic Article GET IT
Times cited: 18
Growing small bowel mucosa: an experimental approach to the short bowel syndrome. Surgical Forum. 1975 Academic Article GET IT
Times cited: 7
Accuracy of Ultrasound in Diagnosing Abdominal Masses. Archives of Surgery. 1975 Academic Article GET IT
Times cited: 23
Cholecystectomy with and without surgical drainage. American journal of surgery. 1975 Academic Article GET IT
Times cited: 31
Gastric mucosal ischemia in experimental stress ulcer. Journal of Surgical Research. 1975 Academic Article GET IT
Times cited: 22
Incidental appendicectomy with laparotomy for trauma. British Journal of Surgery. 1975 Academic Article GET IT
Times cited: 8
Liver failure in the postoperative patient: The role of sepsis and immunologic deficiency. Surgery. 1975 Academic Article GET IT
Times cited: 48
Massive right upper quadrant intra-abdominal injury requiring pancreaticoduodenectomy and partial hepatectomy. Journal of Trauma - Injury, Infection and Critical Care. 1975 Academic Article GET IT
Times cited: 12
Operative Choice and Technique Following Pancreatic Injury. Archives of Surgery. 1975 Academic Article GET IT
Times cited: 37
Replacement of portal vein during pancreatectomy for carcinoma. Surgery. 1975 Academic Article GET IT
Times cited: 60
Liver injuries: Controversies about their treatment. Evaluation of 300 cases. Prensa Medica Argentina. 1974 Academic Article
Times cited: 1
Pharmacological protection against swine stress ulcer. Gastroenterology. 1974 Academic Article GET IT
Times cited: 18
The effects of brain stem compression on the heart. Surgical Neurology. 1974 Academic Article GET IT
Times cited: 3
Management of pseudo-obstruction of the colon. Surgery Gynecology and Obstetrics. 1974 Academic Article GET IT
Times cited: 40
Resident-prepared audio-visual programs for teaching operative technique. Journal of Surgical Research. 1974 Academic Article GET IT
Times cited: 1
Gastric mucosal blood flow measurement. Journal of Surgical Research. 1974 Academic Article GET IT
Times cited: 3
Near total pancreatectomy for hemorrhagic pancreatitis. American journal of surgery. 1974 Academic Article GET IT
Times cited: 42
Bile and stress ulcer. Surgery. 1973 Academic Article
Injuries associated with renal trauma. Journal of Urology. 1973 Academic Article GET IT
Times cited: 10
Liver failure in the surgical patient. BULL.SOC.INT.CHIR.. 1973 Academic Article GET IT
Reply. Surgery. 1973 Information Resource
Growth, inhibition and suppression of mouse melanoma on the isolated perfused pig spleen. Review of surgery. 1973 Academic Article GET IT
Bile reflux in experimental stress ulcer. Surgery. 1973 Academic Article GET IT
Times cited: 24
Gastric Blood Flow in Endotoxin-Induced Stress Ulcer. Archives of Surgery. 1973 Academic Article GET IT
Times cited: 47
Training foreign academicians in U.S. medical schools. Journal of Surgical Research. 1973 Academic Article GET IT
Cardiovascular effects of increased intracranial pressure. Surgical Forum. 1972 Academic Article GET IT
A swine stress ulcer model. Annals of Surgery. 1972 Academic Article GET IT
Times cited: 17
A new venous prosthesis. Surgery. 1972 Academic Article GET IT
Times cited: 193
Gastric secretory response to pressure on vagal nuclei. American journal of surgery. 1972 Academic Article GET IT
Times cited: 12
Immunologic response to melanoma of sensitized perfused bone and spleen. Journal of Surgical Oncology. 1972 Academic Article GET IT
Metabolic and immunologic studies of perfused bone in vitro. Journal of Bone and Joint Surgery - American Volume. 1972 Academic Article GET IT
Times cited: 1
Cyclic adenosine 3', monophosphate 5', thyrocalcitonin, parathyroid hormone, and the isolated perfused bone. Surgical Forum. 1971 Academic Article GET IT
Growth, inhibition and suppression of mouse melanoma on isolated perfused pig spleen. Surgical Forum. 1971 Academic Article GET IT
Times cited: 1
Prolonged experimental bone perfusion. Surgical Forum. 1970 Academic Article GET IT
Times cited: 1
Gastric Secretory Response to Head Injury. Archives of Surgery. 1970 Academic Article GET IT
Times cited: 44
THE ROLE OF SURGERY IN CARCINOMA OF THE UTERINE CERVIX. The Journal of the Kentucky Medical Association. 1964 Academic Article GET IT
Long-Term Comparison Of Vein Patch With Direct Suture: Technique of Anastomosis of Small Arteries. Archives of Surgery. 1964 Academic Article GET IT
Times cited: 11
Coronary Artery Patch Graft: Experiment with Cardiopulmonary Bypass and Hypothermia. Archives of Surgery. 1963 Academic Article GET IT
Times cited: 1

VIVO Weill Cornell Medical College

Larry Norton Professor of Medicine

Publications

Selected publications

Background

Education and Training