Heier, Linda A

Publications

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selected publications

Central nervous system tuberculoma mimicking a brain tumor: A case report. 2023 GET IT
Assessment of Safety and Biodistribution of AAVrh.10hCLN2 Following Intracisternal Administration in Nonhuman Primates for the Treatment of CLN2 Batten Disease. Human gene therapy. 2023 Academic Article GET IT
Cerebral oxygen extraction fraction declines with ventricular enlargement in patients with normal pressure hydrocephalus. Clinical imaging. 2023 Academic Article GET IT
Times cited: 1
Complications in craniosynostosis surgery in patients with rickets: illustrative case and systematic review of literature. Journal of neurosurgery. Case lessons. 2022 Academic Article GET IT
Rapid anatomical imaging of the neonatal brain using T₂ -prepared 3D balanced steady-state free precession. Magnetic resonance in medicine. 2022 Academic Article GET IT
Peripheral neurological complications during COVID-19: A single center experience. Journal of the neurological sciences. 2021 Academic Article GET IT
Times cited: 8
Efficacy of Carboplatin and Isotretinoin in Children With High-risk Medulloblastoma: A Randomized Clinical Trial From the Children's Oncology Group. JAMA oncology. 2021 Academic Article GET IT
Times cited: 62
Evaluation of Transient Ischemic Attack and Minor Stroke: A Rapid Outpatient Model for the COVID-19 Pandemic and Beyond. The Neurohospitalist. 2021 Review GET IT
Times cited: 2
Prevalence and Outcome of Anterior and Middle Cranial Fossae Encephaloceles without Cerebrospinal Fluid Leak or Meningitis. World neurosurgery. 2021 Academic Article GET IT
Times cited: 4
Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing CLN2. Science translational medicine. 2020 Academic Article GET IT
Times cited: 35
Quantitative Whole-Body Imaging of I-124-Labeled Adeno-Associated Viral Vector Biodistribution in Nonhuman Primates. Human gene therapy. 2020 Academic Article GET IT
Times cited: 18
Olfactory Bulb Signal Abnormality in Patients with COVID-19 Who Present with Neurologic Symptoms. AJNR. American journal of neuroradiology. 2020 Academic Article GET IT
Times cited: 35
Phase II Study of Nonmetastatic Desmoplastic Medulloblastoma in Children Younger Than 4 Years of Age: A Report of the Children's Oncology Group (ACNS1221). Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2019 Academic Article GET IT
Times cited: 40
MRI Features of Histologically Diagnosed Supratentorial Primitive Neuroectodermal Tumors and Pineoblastomas in Correlation with Molecular Diagnoses and Outcomes: A Report from the Children's Oncology Group ACNS0332 Trial. AJNR. American journal of neuroradiology. 2019 Academic Article GET IT
Times cited: 12
Cerebral asymmetry during development using linear measures from MRI. Early human development. 2019 Academic Article GET IT
Times cited: 2
Functional Magnetic Resonance Imaging Detects Between-Group Differences in Neural Activation Among Men with Delayed Orgasm Compared with Normal Controls: Preliminary Report. The journal of sexual medicine. 2019 Academic Article GET IT
Times cited: 2
Grading meningiomas utilizing multiparametric MRI with inclusion of susceptibility weighted imaging and quantitative susceptibility mapping. Journal of neuroradiology = Journal de neuroradiologie. 2019 Academic Article GET IT
Times cited: 14
Beals syndrome with middle and inner ear dysplasia and encephalocele: A case report and review of imaging findings. 2018 GET IT
Extensive Molecular and Clinical Heterogeneity in Patients With Histologically Diagnosed CNS-PNET Treated as a Single Entity: A Report From the Children's Oncology Group Randomized ACNS0332 Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2018 Academic Article GET IT
Times cited: 58
Diffusion Weighted/Tensor Imaging, Functional MRI and Perfusion Weighted Imaging in Glioblastoma-Foundations and Future. Frontiers in neurology. 2018 Review GET IT
Times cited: 36
Management of Tiny Meningiomas: To Resect or Not Resect. 2017 GET IT
Prediction of Future Epilepsy in Neonates With Hypoxic-Ischemic Encephalopathy Who Received Selective Head Cooling. Journal of child neurology. 2017 Academic Article GET IT
Times cited: 12
Brain Region-Specific Degeneration with Disease Progression in Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2 Disease). AJNR. American journal of neuroradiology. 2016 Academic Article GET IT
Times cited: 18
MRI assessment of the effects of acetazolamide and external lumbar drainage in idiopathic normal pressure hydrocephalus. Fluids and barriers of the CNS. 2015 Academic Article GET IT
Times cited: 28
Treatment of chronic pain: diffusion tensor imaging identification of the ventroposterolateral nucleus confirmed with successful deep brain stimulation. Stereotactic and functional neurosurgery. 2014 Academic Article GET IT
Times cited: 10
Novel hydrogel application in minimally invasive surgical approaches to spontaneous intracranial hypotension. Report of 2 cases. 2014 GET IT
Times cited: 4
Low-dose acetazolamide reverses periventricular white matter hyperintensities in iNPH. Neurology. 2014 Academic Article GET IT
Times cited: 46
Therapeutic hypothermia in neonates and selective hippocampal injury on diffusion-weighted magnetic resonance imaging. Pediatric neurology. 2014 Academic Article GET IT
Times cited: 14
Diffusion tensor imaging of pyramidal tract reorganization after pediatric stroke. 2014 GET IT
Times cited: 16
Open-label, short-term, repetitive transcranial magnetic stimulation in patients with Alzheimer's disease with functional imaging correlates and literature review. American journal of Alzheimer's disease and other dementias. 2014 Review GET IT
Times cited: 33
Incidental parenchymal magnetic resonance imaging findings in the brains of patients with neurofibromatosis type 2. NeuroImage. Clinical. 2014 Academic Article GET IT
Times cited: 7
Impact of skull base development on endonasal endoscopic surgical corridors. Journal of neurosurgery. Pediatrics. 2013 Academic Article GET IT
Times cited: 35
Differential diagnosis of normal pressure hydrocephalus by MRI mean diffusivity histogram analysis. AJNR. American journal of neuroradiology. 2012 Academic Article GET IT
Times cited: 28
Assessment of disease severity in late infantile neuronal ceroid lipofuscinosis using multiparametric MR imaging. AJNR. American journal of neuroradiology. 2012 Academic Article GET IT
Times cited: 17
Clinical demand for chest/abdomen/pelvis anatomy following thoracic or lumbar spine CT. Emergency radiology. 2012 Academic Article GET IT
Times cited: 1
Using quantitative CT perfusion for evaluation of delayed cerebral ischemia following aneurysmal subarachnoid hemorrhage. AJNR. American journal of neuroradiology. 2011 Academic Article GET IT
Times cited: 65
Arterial spin labeling and altered cerebral blood flow patterns in the minimally conscious state. Neurology. 2011 Academic Article GET IT
Times cited: 29
A pilot study of quantitative MRI measurements of ventricular volume and cortical atrophy for the differential diagnosis of normal pressure hydrocephalus. Neurology research international. 2011 Academic Article GET IT
Times cited: 40
Primary neurosurgery for pediatric low-grade gliomas: a prospective multi-institutional study from the Children's Oncology Group. Neurosurgery. 2011 Academic Article GET IT
Times cited: 152
Dissociations between behavioural and functional magnetic resonance imaging-based evaluations of cognitive function after brain injury. Brain : a journal of neurology. 2011 Academic Article GET IT
Times cited: 236
Multimodal imaging of recovery of functional networks associated with reversal of paradoxical herniation after cranioplasty. Clinical imaging. 2011 Academic Article GET IT
Times cited: 32
Restricted diffusion in the corpus callosum in hypoxic-ischemic encephalopathy. Pediatric neurology. 2010 Academic Article GET IT
Times cited: 13
Gene therapy for late infantile neuronal ceroid lipofuscinosis: neurosurgical considerations. Journal of neurosurgery. Pediatrics. 2010 Academic Article GET IT
Times cited: 59
Acute retinal necrosis and cystic encephalomalacia in a premature neonate. Retinal cases & brief reports. 2010 Academic Article GET IT
Times cited: 1
Ventricular cerebrospinal fluid lactate is increased in chronic fatigue syndrome compared with generalized anxiety disorder: an in vivo 3.0 T (1)H MRS imaging study. NMR in biomedicine. 2009 Academic Article GET IT
Times cited: 58
Treatment of late infantile neuronal ceroid lipofuscinosis by CNS administration of a serotype 2 adeno-associated virus expressing CLN2 cDNA. Human gene therapy. 2008 Academic Article GET IT
Times cited: 295
Accurate localization of brain activity in presurgical FMRI by structure adaptive smoothing. IEEE transactions on medical imaging. 2008 Academic Article GET IT
Times cited: 10
Neurological deterioration in late infantile neuronal ceroid lipofuscinosis. Neurology. 2007 Academic Article GET IT
Times cited: 69
Assessing disease severity in late infantile neuronal ceroid lipofuscinosis using quantitative MR diffusion-weighted imaging. AJNR. American journal of neuroradiology. 2007 Academic Article GET IT
Times cited: 25
Automated analysis of 1H magnetic resonance metabolic imaging data as an aid to clinical decision-making in the evaluation of intracranial lesions. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2007 Academic Article GET IT
Times cited: 1
Diffusion changes in patients with systemic lupus erythematosus. Magnetic resonance imaging. 2006 Academic Article GET IT
Times cited: 50
Diffusion anisotropy changes in the brains of professional boxers. AJNR. American journal of neuroradiology. 2006 Academic Article GET IT
Times cited: 77
Possible axonal regrowth in late recovery from the minimally conscious state. The Journal of clinical investigation. 2006 Academic Article GET IT
Times cited: 284
Multiagent chemotherapy and deferred radiotherapy in infants with malignant brain tumors: a report from the Children's Cancer Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2005 Academic Article GET IT
Times cited: 359
Confronting the issues of therapeutic misconception, enrollment decisions, and personal motives in genetic medicine-based clinical research studies for fatal disorders. Human gene therapy. 2005 Review GET IT
Times cited: 27
Phenotypic features associated with mutations in steroidogenic acute regulatory protein. The Journal of clinical endocrinology and metabolism. 2005 Academic Article GET IT
Times cited: 40
CT angiography in the evaluation of cerebrovascular diseases. AJR. American journal of roentgenology. 2005 Review GET IT
Times cited: 11
Evidence of cerebral reorganization following perinatal stroke demonstrated with fMRI and DTI tractography. 2005 GET IT
Times cited: 39
MR quantitation of volume and diffusion changes in the developing brain. AJNR. American journal of neuroradiology. 2005 Academic Article GET IT
Times cited: 83
Safety and feasibility of using a central venous catheter for rapid contrast injection rates. AJR. American journal of roentgenology. 2004 Academic Article GET IT
Times cited: 38
Clinical protocol. Administration of a replication-deficient adeno-associated virus gene transfer vector expressing the human CLN2 cDNA to the brain of children with late infantile neuronal ceroid lipofuscinosis. Human gene therapy. 2004 Academic Article GET IT
Times cited: 100
Advances in the endoscopic management of suprasellar arachnoid cysts in children. Journal of neurosurgery. 2004 Academic Article GET IT
Times cited: 56
Endovascular management of dolichoectasia of the posterior cerebral artery report. 2004 GET IT
Times cited: 19
Toxic pediatric parkinsonism: report of a child with metabolic studies and response to treatment. 2003 GET IT
Times cited: 2
Use of fetal magnetic resonance imaging in patients electing termination of pregnancy by dilation and evacuation. American journal of obstetrics and gynecology. 2003 Academic Article GET IT
Times cited: 12
Diffusion-tensor MR imaging in children with developmental delay: preliminary findings. Radiology. 2003 Academic Article GET IT
Times cited: 62
Results of preoperative embolization for metastatic spinal neoplasms. Journal of neurosurgery. 2003 Academic Article GET IT
Times cited: 83
Developmental delay in children: assessment with proton MR spectroscopy. AJNR. American journal of neuroradiology. 2002 Academic Article GET IT
Times cited: 64
Internal auditory canal involvement of acoustic neuromas: surgical correlates to magnetic resonance imaging findings. 2001 GET IT
Times cited: 19
Hyperintense signal abnormality in subarachnoid spaces and basal cisterns on MR images of children anesthetized with propofol: new fluid-attenuated inversion recovery finding. AJNR. American journal of neuroradiology. 2001 Academic Article GET IT
Times cited: 41
Appearance of meningiomas on diffusion-weighted images: correlating diffusion constants with histopathologic findings. AJNR. American journal of neuroradiology. 2001 Academic Article GET IT
Times cited: 244
Bilateral paragangliomas with associated venous anomalies. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2001 Academic Article GET IT
Times cited: 1
Large intraosseous arteriovenous malformation of the maxilla - a case report with review of literature. International journal of pediatric otorhinolaryngology. 2000 Review GET IT
Times cited: 14
Incidental discovery of acoustic neuromas. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 1999 Academic Article GET IT
Times cited: 19
Orbital CT. Current use in the MR era. Neuroimaging clinics of North America. 1998 Review GET IT
Times cited: 8
Posterior distribution of infarcts in strokes related to cardiac operations. The Annals of thoracic surgery. 1998 Academic Article GET IT
Times cited: 65
Cogenital bony nasal cavity deformities. American journal of rhinology. 1998 Review GET IT
Times cited: 13
HIV/AIDS case histories: diagnostic problems. Varicella-zoster encephalitis. 1998 GET IT
Epithelioid sarcoma of the neck: a rare tumor mimicking metastatic carcinoma from an unknown primary. 1997 GET IT
Times cited: 11
Magnetic resonance imaging in the congenital adrenal hyperplasia population: increased frequency of white-matter abnormalities and temporal lobe atrophy. Journal of child neurology. 1997 Academic Article GET IT
Times cited: 53
The role of the cranial base in facial growth: experimental craniofacial synostosis in the rabbit. Plastic and reconstructive surgery. 1997 Academic Article GET IT
Times cited: 74
Sensorineural hearing loss and cerebellopontine angle lesions. Not always an acoustic neuroma--a pictorial essay. Clinical imaging. 1997 Review GET IT
Times cited: 7
Juvenile form of Huntington's disease: MR imaging appearance. AJR. American journal of roentgenology. 1995 Review GET IT
Times cited: 7
What are the optimal MR pulse sequences for the detection of intramedullary spinal cord lesions?. AJR. American journal of roentgenology. 1995 Academic Article GET IT
Failure of steroid replacement to consistently normalize pituitary function in congenital adrenal hyperplasia: hormonal and MRI data. Hormone research. 1995 Academic Article GET IT
Times cited: 11
Acquired stuttering after a second stroke in a two-year-old. 1994 GET IT
Times cited: 5
Landau-Kleffner syndrome: temporal lobe tumor resection results in good outcome. 1993 GET IT
Times cited: 28
Bilateral middle cerebral artery occlusions in neurocysticercosis. 1992 GET IT
Times cited: 32
Maternal cocaine abuse: the spectrum of radiologic abnormalities in the neonatal CNS. AJNR. American journal of neuroradiology. 1991 Academic Article GET IT
Times cited: 80
Detection of brain metastases: comparison of contrast-enhanced MR with unenhanced MR and enhanced CT. AJNR. American journal of neuroradiology. 1990 Academic Article GET IT
Times cited: 234
Magnetic resonance imaging of arachnoid cysts. Clinical imaging. 1989 Academic Article GET IT
Times cited: 35
Confirmation by magnetic resonance imaging of Bell's cruciate paralysis in a young child with Chiari type I malformation and minor head trauma. 1989 GET IT
Times cited: 26
Subdural and epidural empyemas: MR imaging. 1989 GET IT
Times cited: 56
Differentiation between meningeal fibrosis and chronic subdural hematoma after ventricular shunting: value of enhanced CT and MR scans. AJNR. American journal of neuroradiology. 1989 Academic Article GET IT
Times cited: 27
Large Virchow-Robin spaces: MR-clinical correlation. AJNR. American journal of neuroradiology. 1989 Academic Article GET IT
Times cited: 298
Magnetic resonance imaging in children of very low birth weight with suspected brain abnormalities. The Journal of pediatrics. 1988 Academic Article GET IT
Times cited: 6
Acute intracranial hemorrhage: intensity changes on sequential MR scans at 0.5 T. AJR. American journal of roentgenology. 1988 Academic Article GET IT
Times cited: 39
Head trauma: comparison of MR and CT--experience in 100 patients. AJNR. American journal of neuroradiology. 1988 Academic Article GET IT
Times cited: 142
Hemorrhagic neoplasms: MR mimics of occult vascular malformations. AJR. American journal of roentgenology. 1987 Academic Article GET IT
Times cited: 44
Tuboovarian abscess presenting as sciatic pain: case report. 1987 GET IT
Times cited: 12
Clinical and magnetic resonance features of primary intracranial arachnoid cysts. 1987 GET IT
Times cited: 34
A dural spinal arteriovenous malformation with epidural venous drainage: a case report. 1987 GET IT
Times cited: 20
Focal recurrent hemorrhage on magnetic resonance at 0.5 tesla. An aid to the diagnosis of cryptic cerebral vascular malformations. Acta radiologica. Supplementum. 1986 Academic Article GET IT
Times cited: 4
Value of magnetic resonance imaging in the evaluation of patients with complete and high degree block due to intracanal neoplasm. Acta radiologica. Supplementum. 1986 Academic Article GET IT
Times cited: 2
Angiographic demonstration of an aorto-left renal vein fistula. 1984 GET IT
Times cited: 5
Biliary disease in metachromatic leukodystrophy. 1983 GET IT
Times cited: 8

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Background

education and training

M.D., University of Western Ontario Faculty of Medicine (Canada) 79
B.S., University of Waterloo (Canada) 1975

Contact

full name

Linda A Heier

primary email

laheier@med.cornell.edu

webpage

Clinical Profile

VIVO Weill Cornell Medical College

Linda A Heier Professor Emerita of Clinical Radiology

Publications

selected publications

Background

education and training

Contact

full name

primary email

webpage