selected publications
- Cancer cells hijack physiological metabolic signals to seed liver metastasis. Cancer research. 2024 Academic Article GET IT
- Mouse Models of Metastasis and Dormancy. Cold Spring Harbor perspectives in medicine. 2023 Academic Article GET IT
- Metastatic well differentiated serotonin-producing pancreatic neuroendocrine tumor with carcinoid heart disease: a case report. 2023 GET IT
- Progressive plasticity during colorectal cancer metastasis. 2023 GET IT
- Micro-engineering and nano-engineering approaches to investigate tumour ecosystems. Nature reviews. Cancer. 2023 Review GET IT
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Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures.
Blood.
2023
Academic Article
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Times cited: 9 -
Metastasis.
Cell.
2023
Review
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Times cited: 78 -
STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma.
Nature.
2023
Academic Article
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Times cited: 10 - Uncoupling Metastasis from Tumorigenesis. The New England journal of medicine. 2023 Comment GET IT
- Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers. Nature communications. 2023 Academic Article GET IT
- Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer. Nature medicine. 2022 Academic Article GET IT
- Characteristics of Mismatch Repair Deficient Colon Cancer in Relation to MMR Protein Loss, Hypermethylation Silencing, and Constitutional and Biallelic Somatic MMR Gene Pathogenic Variants. Diseases of the colon and rectum. 2022 Academic Article GET IT
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Lymphatics act as a signaling hub to regulate intestinal stem cell activity.
Cell stem cell.
2022
Academic Article
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Times cited: 43 - The Role of the TP53 Pathway in Predicting Response to Neoadjuvant Therapy in Esophageal Adenocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2022 Academic Article GET IT
- Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients. Cell. 2022 Academic Article GET IT
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Optimizing immunotherapy for colorectal cancer.
Nature reviews. Gastroenterology & hepatology.
2022
Review
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Times cited: 30 - Breaking up MTDH-SND1 to break down metastasis. Nature cancer. 2022 Comment GET IT
- A Comprehensive Comparison of Early-Onset and Average-Onset Colorectal Cancers. Journal of the National Cancer Institute. 2021 Academic Article GET IT
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The joys and challenges of being a physician-scientist.
Nature reviews. Gastroenterology & hepatology.
2021
Academic Article
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Times cited: 3 - Tumor-Infiltrating Lymphocytes, Tumor Mutational Burden, and Genetic Alterations in Microsatellite Unstable, Microsatellite Stable, or Mutant POLE/POLD1 Colon Cancer. JCO precision oncology. 2021 Academic Article GET IT
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Initial evaluation of dual-energy computed tomography as an imaging biomarker for hepatic metastases from neuroendocrine tumor of the gastrointestinal tract.
Quantitative imaging in medicine and surgery.
2021
Academic Article
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Times cited: 1 -
Metastasis-Initiating Cells and Ecosystems.
Cancer discovery.
2021
Review
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Times cited: 118 -
Phase II Single-arm Study of Durvalumab and Tremelimumab with Concurrent Radiotherapy in Patients with Mismatch Repair-proficient Metastatic Colorectal Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2021
Academic Article
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Times cited: 4 -
Targeting metastatic cancer.
Nature medicine.
2021
Review
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Times cited: 422 -
Characterization and Clinical Outcomes of DNA Mismatch Repair-deficient Small Bowel Adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2020
Academic Article
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Times cited: 21 -
Lineage Reversion Drives WNT Independence in Intestinal Cancer.
Cancer discovery.
2020
Academic Article
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Times cited: 42 -
Plasticity in Motion: Shape-Shifting Lgr5-Cells Initiate Colorectal Cancer Metastasis.
Cell stem cell.
2020
Comment
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Times cited: 3 -
L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer.
Nature cancer.
2020
Academic Article
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Times cited: 123 -
Coaltered Ras/B-raf and TP53 Is Associated with Extremes of Survivorship and Distinct Patterns of Metastasis in Patients with Metastatic Colorectal Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2019
Academic Article
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Times cited: 55 -
A rectal cancer organoid platform to study individual responses to chemoradiation.
Nature medicine.
2019
Academic Article
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Times cited: 300 -
Colorectal carcinoma with double somatic mismatch repair gene inactivation: clinical and pathological characteristics and response to immune checkpoint blockade.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2019
Academic Article
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Times cited: 12 -
Immunotherapy in colorectal cancer: rationale, challenges and potential.
Nature reviews. Gastroenterology & hepatology.
2019
Information Resource
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Times cited: 962 -
Assessment of a Watch-and-Wait Strategy for Rectal Cancer in Patients With a Complete Response After Neoadjuvant Therapy.
JAMA oncology.
2019
Academic Article
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Times cited: 347 -
Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization.
eLife.
2019
Academic Article
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Times cited: 42 -
Author Correction: Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization.
2019
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Times cited: 3 -
SMAD4 Loss in Colorectal Cancer Patients Correlates with Recurrence, Loss of Immune Infiltrate, and Chemoresistance.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
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Times cited: 67 -
Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization.
Nature cell biology.
2018
Academic Article
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Times cited: 166 -
Quantitative self-assembly prediction yields targeted nanomedicines.
Nature materials.
2018
Academic Article
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Times cited: 136 -
Clinical and genetic determinants of ovarian metastases from colorectal cancer.
Cancer.
2016
Academic Article
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Times cited: 48 -
CTNNBL1 facilitates the association of CWC15 with CDC5L and is required to maintain the abundance of the Prp19 spliceosomal complex.
Nucleic acids research.
2015
Academic Article
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Times cited: 11 -
Structural and mutational analysis reveals that CTNNBL1 binds NLSs in a manner distinct from that of its closest armadillo-relative, karyopherin α.
FEBS letters.
2013
Academic Article
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Times cited: 5