selected publications
- The evolution of metastatic upper tract urothelial carcinoma through genomic-transcriptomic and single-cell protein markers analysis. Nature communications. 2024 Academic Article GET IT
- Whole-Genome Sequencing Analysis of Male Breast Cancer Unveils Novel Structural Events and Potential Therapeutic Targets. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2024 Academic Article GET IT
- Cooperativity of c-MYC with Krüppel-Like Factor 6 Splice Variant 1 induces phenotypic plasticity and promotes prostate cancer progression and metastasis. 2024 GET IT
- Deciphering the origin and therapeutic targets of cancer of unknown primary: a case report that illustrates the power of integrative whole-exome and transcriptome sequencing analysis. 2024 GET IT
- NIPBL::NACC1 Fusion Hepatic Carcinoma. The American journal of surgical pathology. 2023 Academic Article GET IT
- Author Correction: Evolution of structural rearrangements in prostate cancer intracranial metastases. 2023 GET IT
- Evolution of structural rearrangements in prostate cancer intracranial metastases. NPJ precision oncology. 2023 Academic Article GET IT
- The importance of escalating molecular diagnostics in patients with low-grade pediatric brain cancer. Cold Spring Harbor molecular case studies. 2023 Academic Article GET IT
- Long-molecule scars of backup DNA repair in BRCA1- and BRCA2-deficient cancers. Nature. 2023 Academic Article GET IT
- The Immunogenomic Landscape of Neuroendocrine Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Academic Article GET IT
- Whole-genome characterization of myoepithelial carcinomas of the soft tissue. Cold Spring Harbor molecular case studies. 2022 Academic Article GET IT
- Unsupervised discovery of tissue architecture in multiplexed imaging. Nature methods. 2022 Academic Article GET IT
- GLI1-Rearranged Enteric Tumor: Expanding the Spectrum of Gastrointestinal Neoplasms with GLI1 gene fusions. The American journal of surgical pathology. 2022 Academic Article GET IT
- Identifying synergistic high-order 3D chromatin conformations from genome-scale nanopore concatemer sequencing. Nature biotechnology. 2022 Academic Article GET IT
- Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets. Science (New York, N.Y.). 2022 Academic Article GET IT
- Weakly-supervised tumor purity prediction from frozen H&E stained slides. EBioMedicine. 2022 Academic Article GET IT
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Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET-rearranged thyroid cancer.
The Journal of experimental medicine.
2022
Academic Article
GET IT
Times cited: 7 - A multidisciplinary approach to optimize primary prostate cancer biobanking. Urologic oncology. 2022 Academic Article GET IT
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RET Fusion-Positive Papillary Thyroid Cancers are Associated with a More Aggressive Phenotype.
Annals of surgical oncology.
2022
Academic Article
GET IT
Times cited: 7 - The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy. Molecular oncology. 2022 Academic Article GET IT
- Comparative genomics of primary prostate cancer and paired metastases: insights from 12 molecular case studies. The Journal of pathology. 2022 Academic Article GET IT
- Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci. JCI insight. 2022 Academic Article GET IT
- Serial ctDNA analysis predicts clinical progression in patients with advanced urothelial carcinoma. British journal of cancer. 2022 Academic Article GET IT
- Extracellular Matrix in Synthetic Hydrogel-based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 inhibitors. Advanced materials (Deerfield Beach, Fla.). 2021 Academic Article GET IT
- Molecular Evaluation of Low-grade Low-stage Endometrial Cancer With and Without Recurrence. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 2021 Academic Article GET IT
- Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis. NPJ precision oncology. 2021 Academic Article GET IT
- Functional comparison of exome capture-based methods for transcriptomic profiling of formalin-fixed paraffin-embedded tumors. NPJ genomic medicine. 2021 Academic Article GET IT
- Validation of a Circulating Tumor DNA-Based Next-Generation Sequencing Assay in a Cohort of Patients with Solid tumors: A Proposed Solution for Decentralized Plasma Testing. The oncologist. 2021 Academic Article GET IT
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Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia.
NPJ precision oncology.
2021
Academic Article
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Times cited: 19 - Incorporating cytologic adequacy assessment into precision oncology workflow using telepathology: An institutional experience. Cancer cytopathology. 2021 Academic Article GET IT
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Common germline-somatic variant interactions in advanced urothelial cancer.
Nature communications.
2020
Academic Article
GET IT
Times cited: 19 -
Performance Characteristics of a Targeted Sequencing Platform for Simultaneous Detection of Single Nucleotide Variants, Insertions/Deletions, Copy Number Alterations, and Gene Fusions in Cancer Genome.
Archives of pathology & laboratory medicine.
2020
Academic Article
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Times cited: 1 -
Feasibility of in-office MRI-targeted partial gland cryoablation for prostate cancer: an IDEAL stage 2A study.
BMJ surgery, interventions, & health technologies.
2020
Academic Article
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Times cited: 5 -
Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncology.
Translational oncology.
2020
Academic Article
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Times cited: 9 -
Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs.
Cell.
2020
Academic Article
GET IT
Times cited: 104 - Contemporary Results and Clinical Utility of Renal Mass Biopsies in the Setting of Ablative Therapy: A single center experience. Cancer treatment and research communications. 2020 Academic Article GET IT
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Molecular Profiles of Mixed Endometrial Carcinoma.
The American journal of surgical pathology.
2020
Academic Article
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Times cited: 3 -
Neuroendocrine differentiation in usual-type prostatic adenocarcinoma: Molecular characterization and clinical significance.
The Prostate.
2020
Academic Article
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Times cited: 4 -
Next-generation sequencing of residual cytologic fixative preserved DNA from pancreatic lesions: A pilot study.
Cancer cytopathology.
2020
Academic Article
GET IT
Times cited: 1 -
Fusions involving BCOR and CREBBP are rare events in infiltrating glioma.
Acta neuropathologica communications.
2020
Academic Article
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Times cited: 12 -
Adenomyoepithelial tumors of the breast: molecular underpinnings of a rare entity.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2020
Academic Article
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Times cited: 4 -
Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes.
Nature communications.
2020
Academic Article
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Times cited: 33 -
Circulating tumor DNA profile recognizes transformation to castration-resistant neuroendocrine prostate cancer.
The Journal of clinical investigation.
2020
Academic Article
GET IT
Times cited: 109 - SLFN11 Expression in Advanced Prostate Cancer and Response to Platinum-based Chemotherapy. Molecular cancer therapeutics. 2020 Academic Article GET IT
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Prostate Multiparametric Magnetic Resonance Imaging Features Following Partial Gland Cryoablation.
Urology.
2020
Academic Article
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Times cited: 2 -
Integrative Molecular Analysis of Patients With Advanced and Metastatic Cancer.
JCO precision oncology.
2019
Academic Article
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Times cited: 31 -
Clinical features of neuroendocrine prostate cancer.
European journal of cancer.
2019
Academic Article
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Times cited: 177 -
Race and prostate imaging: implications for targeted biopsy and image-based prostate cancer interventions.
BMJ surgery, interventions, & health technologies.
2019
Academic Article
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Times cited: 1 -
Cancer-Specific Thresholds Adjust for Whole Exome Sequencing-based Tumor Mutational Burden Distribution.
JCO precision oncology.
2019
Academic Article
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Times cited: 22 -
The Clinical Utility of the Genomic Prostate Score in Men with Very Low to Intermediate Risk Prostate Cancer.
The Journal of urology.
2019
Academic Article
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Times cited: 2 -
Genomic correlates of clinical outcome in advanced prostate cancer.
Proceedings of the National Academy of Sciences of the United States of America.
2019
Academic Article
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Times cited: 703 -
Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer.
Science translational medicine.
2019
Academic Article
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Times cited: 100 - Gynecologic Organ Involvement During Radical Cystectomy for Bladder Cancer: Is It Time to Routinely Spare the Ovaries?. Clinical genitourinary cancer. 2018 Academic Article GET IT
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Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate.
Molecular cancer research : MCR.
2018
Academic Article
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Times cited: 40 -
A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
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Times cited: 155 -
Patient derived organoids to model rare prostate cancer phenotypes.
Nature communications.
2018
Academic Article
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Times cited: 229 -
Bone biopsy protocol for advanced prostate cancer in the era of precision medicine.
Cancer.
2017
Academic Article
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Times cited: 38 -
SPOP mutation drives prostate neoplasia without stabilizing oncogenic transcription factor ERG.
The Journal of clinical investigation.
2017
Academic Article
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Times cited: 26 -
Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance.
Cancer cell.
2017
Academic Article
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Times cited: 49 - A Precious Diagnostic "Pearl": The Necklace Pattern in Germ Cell Tumors of the Testis. 2017 GET IT
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Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics.
Journal of translational medicine.
2017
Academic Article
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Times cited: 5 -
Molecular alterations in prostate cancer and association with MRI features.
Prostate cancer and prostatic diseases.
2017
Academic Article
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Times cited: 13 -
Next-Generation Rapid Autopsies Enable Tumor Evolution Tracking and Generation of Preclinical Models.
JCO precision oncology.
2017
Academic Article
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Times cited: 39 -
Characterization of CD34-deficient myofibroblastomas of the breast.
The breast journal.
2017
Academic Article
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Times cited: 3 -
Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations.
Cancer discovery.
2017
Academic Article
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Times cited: 84 -
Co-clinical Analysis of a Genetically Engineered Mouse Model and Human Prostate Cancer Reveals Significance of NKX3.1 Expression for Response to 5α-reductase Inhibition.
European urology.
2017
Academic Article
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Times cited: 16 -
On-site Cytology for Development of Patient-Derived Three-dimensional Organoid Cultures - A Pilot Study.
Anticancer research.
2017
Academic Article
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Times cited: 5 -
Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine.
Cancer discovery.
2017
Academic Article
GET IT
Times cited: 668 - Two cases of atypical hemolytic uremic syndrome (aHUS) and eosinophilic granulomatosis with polyangiitis (EGPA): a possible relationship. CEN case reports. 2017 Academic Article GET IT
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Clonal evolution of chemotherapy-resistant urothelial carcinoma.
Nature genetics.
2016
Academic Article
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Times cited: 217 -
N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
Cancer cell.
2016
Academic Article
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Times cited: 365 -
Characterization of the leiomyomatous variant of myofibroblastoma: a rare subset distinct from other smooth muscle tumors of the breast.
Human pathology.
2016
Academic Article
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Times cited: 4 -
Development and validation of a whole-exome sequencing test for simultaneous detection of point mutations, indels and copy-number alterations for precision cancer care.
NPJ genomic medicine.
2016
Academic Article
GET IT
Times cited: 62 -
Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer.
Nature medicine.
2016
Academic Article
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Times cited: 1046 -
Intracellular location of BRCA2 protein expression and prostate cancer progression in the Swedish Watchful Waiting Cohort.
Carcinogenesis.
2016
Academic Article
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Times cited: 6 -
Clonal evaluation of prostate cancer foci in biopsies with discontinuous tumor involvement by dual ERG/SPINK1 immunohistochemistry.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2016
Academic Article
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Times cited: 23 -
The Initial Detection and Partial Characterization of Circulating Tumor Cells in Neuroendocrine Prostate Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2015
Academic Article
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Times cited: 109 -
The Placental Gene PEG10 Promotes Progression of Neuroendocrine Prostate Cancer.
Cell reports.
2015
Academic Article
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Times cited: 135 -
Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.
JAMA oncology.
2015
Academic Article
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Times cited: 226 -
Integrative clinical genomics of advanced prostate cancer.
Cell.
2015
Academic Article
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Times cited: 2321 -
Multicenter Evaluation of the Prostate Health Index to Detect Aggressive Prostate Cancer in Biopsy Naïve Men.
The Journal of urology.
2015
Academic Article
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Times cited: 132 -
ERG induces taxane resistance in castration-resistant prostate cancer.
Nature communications.
2014
Academic Article
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Times cited: 93 -
The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer.
Nature communications.
2014
Academic Article
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Times cited: 516 -
Organoid cultures derived from patients with advanced prostate cancer.
Cell.
2014
Academic Article
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Times cited: 1065 -
Unraveling the clonal hierarchy of somatic genomic aberrations.
Genome biology.
2014
Academic Article
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Times cited: 78 -
MYB-NFIB gene fusion in adenoid cystic carcinoma of the breast with special focus paid to the solid variant with basaloid features.
Human pathology.
2014
Academic Article
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Times cited: 44 -
Evidence for molecular differences in prostate cancer between African American and Caucasian men.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2014
Academic Article
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Times cited: 127 -
Prostate cancer with Paneth cell-like neuroendocrine differentiation has recognizable histomorphology and harbors AURKA gene amplification.
Human pathology.
2014
Academic Article
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Times cited: 27 -
Proposed morphologic classification of prostate cancer with neuroendocrine differentiation.
The American journal of surgical pathology.
2014
Academic Article
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Times cited: 396 -
Recurrent prostate cancer genomic alterations predict response to brachytherapy treatment.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2014
Academic Article
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Times cited: 22 -
SPOP mutations in prostate cancer across demographically diverse patient cohorts.
Neoplasia (New York, N.Y.).
2014
Academic Article
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Times cited: 120 -
Diagnostic utility of MYC amplification and anti-MYC immunohistochemistry in atypical vascular lesions, primary or radiation-induced mammary angiosarcomas, and primary angiosarcomas of other sites.
Human pathology.
2013
Academic Article
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Times cited: 63 -
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing.
Nature biotechnology.
2013
Academic Article
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Times cited: 1611 -
Novel MIR143-NOTCH fusions in benign and malignant glomus tumors.
Genes, chromosomes & cancer.
2013
Academic Article
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Times cited: 128 -
V-ets erythroblastosis virus E26 oncogene homolog (avian)/Trefoil factor 3/high-molecular-weight cytokeratin triple immunostain: a novel tissue-based biomarker in prostate cancer with potential clinical application.
Human pathology.
2013
Academic Article
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Times cited: 5 -
Comprehensive molecular characterization of clear cell renal cell carcinoma.
Nature.
2013
Academic Article
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Times cited: 1721 -
Novel YAP1-TFE3 fusion defines a distinct subset of epithelioid hemangioendothelioma.
Genes, chromosomes & cancer.
2013
Academic Article
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Times cited: 404 -
Frequent PLAG1 gene rearrangements in skin and soft tissue myoepithelioma with ductal differentiation.
Genes, chromosomes & cancer.
2013
Academic Article
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Times cited: 108 -
Punctuated evolution of prostate cancer genomes.
Cell.
2013
Academic Article
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Times cited: 960 - Epigenomic alterations in localized and advanced prostate cancer. Neoplasia (New York, N.Y.). 2013 Academic Article GET IT
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Recurrent NCOA2 gene rearrangements in congenital/infantile spindle cell rhabdomyosarcoma.
Genes, chromosomes & cancer.
2013
Academic Article
GET IT
Times cited: 184 -
Dedifferentiation in gastrointestinal stromal tumor to an anaplastic KIT-negative phenotype: a diagnostic pitfall: morphologic and molecular characterization of 8 cases occurring either de novo or after imatinib therapy.
The American journal of surgical pathology.
2013
Academic Article
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Times cited: 80 -
Distinct ERG rearrangement prevalence in prostate cancer: higher frequency in young age and in low PSA prostate cancer.
Prostate cancer and prostatic diseases.
2013
Academic Article
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Times cited: 61 -
Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2013
Academic Article
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Times cited: 42 -
Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing.
Nature genetics.
2013
Academic Article
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Times cited: 603 -
Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer.
Neoplasia (New York, N.Y.).
2013
Academic Article
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Times cited: 198 -
Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression.
Cancer research.
2012
Academic Article
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Times cited: 152 -
Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity.
European urology.
2012
Academic Article
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Times cited: 344 -
Loss of SPINK1 expression is associated with unfavorable outcomes in urothelial carcinoma of the bladder after radical cystectomy.
Urologic oncology.
2012
Academic Article
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Times cited: 9 -
Oncogene-mediated alterations in chromatin conformation.
Proceedings of the National Academy of Sciences of the United States of America.
2012
Academic Article
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Times cited: 112 -
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer.
Nature genetics.
2012
Academic Article
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Times cited: 1199 -
Validation of a TFE3 break-apart FISH assay for Xp11.2 translocation renal cell carcinomas.
Diagnostic molecular pathology : the American journal of surgical pathology, part B.
2011
Academic Article
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Times cited: 54 -
Novel ZEB1 expression in bladder tumorigenesis.
BJU international.
2010
Academic Article
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Times cited: 45 -
Identification of the transcription factor single-minded homologue 2 as a potential biomarker and immunotherapy target in prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2009
Academic Article
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Times cited: 141 -
Expanding the spectrum of malignant progression in solitary fibrous tumors: a study of 8 cases with a discrete anaplastic component--is this dedifferentiated SFT?.
The American journal of surgical pathology.
2009
Academic Article
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Times cited: 162 -
Prevalence of TMPRSS2-ERG fusion prostate cancer among men undergoing prostate biopsy in the United States.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2009
Academic Article
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Times cited: 200 -
Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2008
Academic Article
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Times cited: 175 -
Integrative microarray analysis of pathways dysregulated in metastatic prostate cancer.
Cancer research.
2007
Academic Article
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Times cited: 60 -
TMPRSS2-ERG fusion prostate cancer: an early molecular event associated with invasion.
The American journal of surgical pathology.
2007
Academic Article
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Times cited: 336 -
Morphological features of TMPRSS2-ERG gene fusion prostate cancer.
The Journal of pathology.
2007
Academic Article
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Times cited: 103 -
TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort.
Oncogene.
2007
Academic Article
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Times cited: 515 -
TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer.
Cancer research.
2006
Academic Article
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Times cited: 417 -
Tumor gene expression and prognosis in breast cancer patients with 10 or more positive lymph nodes.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2005
Academic Article
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Times cited: 167 -
The phosphorylated form of connexin43 is up-regulated in breast hyperplasias and carcinomas and in their neoformed capillaries.
Human pathology.
2005
Academic Article
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Times cited: 14 -
Immunolocalization of the Epstein-Barr nuclear antigen-1 in conjunctival squamous carcinomas and dysplasias.
Human pathology.
2005
Academic Article
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Times cited: 8 -
Oestrogen receptors alpha and beta differ in normal human breast and breast carcinomas.
The Journal of pathology.
2002
Academic Article
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Times cited: 85 -
Antifungal triazoles and polymorphonuclear leukocytes synergize to cause increased hyphal damage to Scedosporium prolificans and Scedosporium apiospermum.
Antimicrobial agents and chemotherapy.
2002
Academic Article
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Times cited: 58