Krueger, James Glenn

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Comparison of the Inflammatory Circuits in Psoriasis Vulgaris, Non-Pustular Palmoplantar Psoriasis, and Palmoplantar Pustular Psoriasis. The Journal of investigative dermatology. 2022 Academic Article GET IT
Analysis of alopecia areata surveys suggests a threshold for improved patient-reported outcomes. The British journal of dermatology. 2022 Academic Article GET IT
Interleukin-17RA blockade by brodalumab decreases inflammatory pathways in hidradenitis suppurativa skin and serum. The British journal of dermatology. 2022 Academic Article GET IT
Times cited: 20
Secukinumab improves mild-to-moderate psoriasis: A randomized, placebo-controlled exploratory clinical trial. Journal of the American Academy of Dermatology. 2022 Academic Article GET IT
Ustekinumab reduces serum protein levels associated with cardiovascular risk in psoriasis vulgaris. Experimental dermatology. 2022 Academic Article GET IT
Transcriptomic Analysis of the Major Orphan Ichthyosis Subtypes Reveals Shared Immune and Barrier Signatures. The Journal of investigative dermatology. 2022 Academic Article GET IT
Times cited: 1
Treatment Options and Goals for Patients with Generalized Pustular Psoriasis. American journal of clinical dermatology. 2022 Review GET IT
Times cited: 54
A Randomized Open Label Clinical Trial of Lipid-Lowering Therapy in Psoriasis to Reduce Vascular Endothelial Inflammation. The Journal of investigative dermatology. 2021 Academic Article GET IT
Molecular and clinical effects of selective tyrosine kinase 2 inhibition with deucravacitinib in psoriasis. The Journal of allergy and clinical immunology. 2021 Academic Article GET IT
Effect of Costimulatory Blockade With Abatacept After Ustekinumab Withdrawal in Patients With Moderate to Severe Plaque Psoriasis: The PAUSE Randomized Clinical Trial. JAMA dermatology. 2021 Academic Article GET IT
Times cited: 9
Bimekizumab for the treatment of moderate-to-severe plaque psoriasis: efficacy, safety, pharmacokinetics, pharmacodynamics and transcriptomics from a phase IIa, randomized, double-blind multicentre study. The British journal of dermatology. 2021 Academic Article GET IT
Pustular psoriasis: Molecular pathways and effects of spesolimab in generalized pustular psoriasis. The Journal of allergy and clinical immunology. 2021 Academic Article GET IT
Transcriptomic Profiling of Tape-Strips From Moderate to Severe Atopic Dermatitis Patients Treated With Dupilumab. Dermatitis : contact, atopic, occupational, drug. 2021 Academic Article GET IT
Response to 'Lack of efficacy of dupilumab in the treatment of keloid disorder' by MH Tirgan and J Uitto. Journal of the European Academy of Dermatology and Venereology : JEADV. 2021 Letter GET IT
Phase 2a randomized clinical trial of dupilumab (anti-IL-4Rα) for alopecia areata patients. Allergy. 2021 Academic Article GET IT
Times cited: 1
T_H 2 cytokines and Staphylococcus aureus cooperatively induce atopic dermatitis-like transcriptomes. Allergy. 2021 Letter GET IT
Assessing the responsiveness of sonographic biomarkers to Brodalumab therapy in Hidradenitis Suppurativa. Journal of the European Academy of Dermatology and Venereology : JEADV. 2021 Letter GET IT
The Rockefeller Team Science Leadership training program: Curriculum, standardized assessment of competencies, and impact of returning assessments. Journal of clinical and translational science. 2021 Academic Article GET IT
The inflammatory proteome of hidradenitis suppurativa skin is more expansive than that of psoriasis vulgaris. Journal of the American Academy of Dermatology. 2021 Academic Article GET IT
Capsaicin attenuates imiquimod-induced epidermal hyperplasia and cutaneous inflammation in a murine model of psoriasis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Academic Article GET IT
Times cited: 1
Large-scale serum analysis identifies unique systemic biomarkers in psoriasis and hidradenitis suppurativa. The British journal of dermatology. 2021 Academic Article GET IT
Tyrosine kinase 2 and Janus kinase‒signal transducer and activator of transcription signaling and inhibition in plaque psoriasis. Journal of the American Academy of Dermatology. 2021 Information Resource GET IT
The Busy Arena of Psoriasis Treatments: Improving the Clinician's Ability to Make the Right Therapeutic Choice. American journal of clinical dermatology. 2021 Article GET IT
The Impact of Body Mass Index Upon the Efficacy of Adalimumab in Hidradenitis Suppurativa. Frontiers in medicine. 2021 Academic Article GET IT
High inflammation in hidradenitis suppurativa extends to perilesional skin and can be subdivided by lipocalin-2 expression. The Journal of allergy and clinical immunology. 2021 Academic Article GET IT
Signalling of multiple interleukin (IL)-17 family cytokines via IL-17 receptor A drives psoriasis-related inflammatory pathways. The British journal of dermatology. 2021 Academic Article GET IT
Times cited: 2
Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement. Journal of the American Academy of Dermatology. 2021 Academic Article GET IT
Immune and barrier characterization of atopic dermatitis skin phenotype in Tanzanian patients. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2021 Academic Article GET IT
Deep learning automated pathology in ex vivo microscopy. Biomedical optics express. 2021 Academic Article GET IT
Single-cell transcriptomics applied to emigrating cells from psoriasis elucidate pathogenic versus regulatory immune cell subsets. The Journal of allergy and clinical immunology. 2021 Academic Article GET IT
Times cited: 1
Vascular inflammation in moderate-to-severe atopic dermatitis is associated with enhanced Th2 response. Allergy. 2021 Academic Article GET IT
Cardiovascular Risk in Patients With Psoriasis: JACC Review Topic of the Week. Journal of the American College of Cardiology. 2021 Information Resource GET IT
High-dimensional analysis defines multicytokine T-cell subsets and supports a role for IL-21 in atopic dermatitis. Allergy. 2021 Academic Article GET IT
In-Depth Analysis of the Hidradenitis Suppurativa Serum Proteome Identifies Distinct Inflammatory Subtypes. The Journal of investigative dermatology. 2021 Academic Article GET IT
Times cited: 30
An integrated scalp and blood biomarker approach suggests the systemic nature of alopecia areata. Allergy. 2021 Academic Article GET IT
Bimekizumab efficacy and safety in moderate to severe plaque psoriasis (BE READY): a multicentre, double-blind, placebo-controlled, randomised withdrawal phase 3 trial. Lancet (London, England). 2021 Academic Article GET IT
Times cited: 15
Epithelialized tunnels are a source of inflammation in hidradenitis suppurativa. The Journal of allergy and clinical immunology. 2021 Academic Article GET IT
Times cited: 51
The molecular features of normal and atopic dermatitis skin in infants, children, adolescents, and adults. The Journal of allergy and clinical immunology. 2021 Academic Article GET IT
Times cited: 4
The erythema Q-score, an imaging biomarker for redness in skin inflammation. Experimental dermatology. 2020 Academic Article GET IT
Times cited: 8
CCL20 in psoriasis: A potential biomarker of disease severity, inflammation, and impaired vascular health. Journal of the American Academy of Dermatology. 2020 Academic Article GET IT
International observational atopic dermatitis cohort to follow natural history and treatment course: TARGET-DERM AD study design and rationale. BMJ open. 2020 Academic Article GET IT
RNA Sequencing Keloid Transcriptome Associates Keloids With Th2, Th1, Th17/Th22, and JAK3-Skewing. Frontiers in immunology. 2020 Academic Article GET IT
Times cited: 47
Quantifying the natural variation in lesion counts over time in untreated hidradenitis suppurativa: Implications for outcome measures and trial design. JAAD international. 2020 Academic Article GET IT
Deep learning-level melanoma detection by interpretable machine learning and imaging biomarker cues. Journal of biomedical optics. 2020 Academic Article GET IT
Dermal tunnels influence time to clinical response and family history influences time to loss of clinical response in patients with hidradenitis suppurativa treated with adalimumab. Clinical and experimental dermatology. 2020 Academic Article GET IT
Times cited: 5
Mild atopic dermatitis lacks systemic inflammation and shows reduced nonlesional skin abnormalities. The Journal of allergy and clinical immunology. 2020 Academic Article GET IT
Times cited: 3
Weekly administration of brodalumab in hidradenitis suppurativa: an open-label cohort study. The British journal of dermatology. 2020 Article GET IT
Times cited: 2
A phase I, randomized, double-blind study to assess the safety, tolerability and efficacy of the topical RORC2 inverse agonist PF-06763809 in participants with mild-to-moderate plaque psoriasis. Clinical and experimental dermatology. 2020 Academic Article GET IT
Times cited: 9
Doppler ultrasound-based noninvasive biomarkers in hidradenitis suppurativa: evaluation of analytical and clinical validity. The British journal of dermatology. 2020 Academic Article GET IT
Times cited: 22
Tape-strips provide a minimally invasive approach to track therapeutic response to topical corticosteroids in atopic dermatitis patients. The journal of allergy and clinical immunology. In practice. 2020 Academic Article GET IT
Times cited: 5
SARS-CoV-2 receptor ACE2 protein expression in serum is significantly associated with age. Allergy. 2020 Article GET IT
Times cited: 24
Obesity and ethnicity alter gene expression in skin. Scientific reports. 2020 Academic Article GET IT
Tape strips from early-onset pediatric atopic dermatitis highlight disease abnormalities in nonlesional skin. Allergy. 2020 Academic Article GET IT
Times cited: 10
A Preliminary ¹⁸F-FDG-PET/MRI Study Shows Increased Vascular Inflammation in Moderate-to-Severe Atopic Dermatitis. The journal of allergy and clinical immunology. In practice. 2020 Academic Article GET IT
Times cited: 11
Tape strips detect distinct immune and barrier profiles in atopic dermatitis and psoriasis. The Journal of allergy and clinical immunology. 2020 Academic Article GET IT
Times cited: 20
Improving evaluation of drugs in atopic dermatitis by combining clinical and molecular measures. The journal of allergy and clinical immunology. In practice. 2020 Academic Article GET IT
Times cited: 3
A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue. Oncotarget. 2020 Academic Article GET IT
Times cited: 17
Response to Inhibition of Receptor-Interacting Protein Kinase 1 (RIPK1) in Active Plaque Psoriasis: A Randomized Placebo-Controlled Study. Clinical pharmacology and therapeutics. 2020 Academic Article GET IT
Times cited: 49
A systematic review and critical appraisal of metagenomic and culture studies in hidradenitis suppurativa. Experimental dermatology. 2020 Academic Article GET IT
Times cited: 17
Characterization of PCSK9 in the Blood and Skin of Psoriasis. The Journal of investigative dermatology. 2020 Academic Article GET IT
Times cited: 5
Frontal fibrosing alopecia shows robust T helper 1 and Janus kinase 3 skewing. The British journal of dermatology. 2020 Academic Article GET IT
Times cited: 9
Malignancy and infection risk during adalimumab therapy in hidradenitis suppurativa. Clinical and experimental dermatology. 2020 Academic Article GET IT
Times cited: 3
The effect of subcutaneous brodalumab on clinical disease activity in hidradenitis suppurativa: An open-label cohort study. Journal of the American Academy of Dermatology. 2020 Academic Article GET IT
Times cited: 68
NFI transcription factors provide chromatin access to maintain stem cell identity while preventing unintended lineage fate choices. Nature cell biology. 2020 Academic Article GET IT
Times cited: 46
Cross-sectional study of blood biomarkers of patients with moderate to severe alopecia areata reveals systemic immune and cardiovascular biomarker dysregulation. Journal of the American Academy of Dermatology. 2020 Academic Article GET IT
Times cited: 11
Beyond antibodies: B cells in Hidradenitis Suppurativa: Bystanders, contributors or therapeutic targets?. Experimental dermatology. 2020 Academic Article GET IT
Activated Platelets Induce Endothelial Cell Inflammatory Response in Psoriasis via COX-1. Arteriosclerosis, thrombosis, and vascular biology. 2020 Academic Article GET IT
Times cited: 47
The aging skin microenvironment dictates stem cell behavior. Proceedings of the National Academy of Sciences of the United States of America. 2020 Academic Article GET IT
Times cited: 89
Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis. The Journal of allergy and clinical immunology. 2020 Academic Article GET IT
Times cited: 43
Defining drug-free remission of skin disease in patients with plaque psoriasis. The British journal of dermatology. 2020 Article GET IT
Molecular and Cellular Responses to the TYK2/JAK1 Inhibitor PF-06700841 Reveal Reduction of Skin Inflammation in Plaque Psoriasis. The Journal of investigative dermatology. 2020 Academic Article GET IT
Times cited: 13
Short-term transcriptional response to IL-17 receptor-A antagonism in the treatment of psoriasis. The Journal of allergy and clinical immunology. 2019 Academic Article GET IT
Times cited: 8
Clinical response rates, placebo response rates, and significantly associated covariates are dependent on choice of outcome measure in hidradenitis suppurativa: A post hoc analysis of PIONEER 1 and 2 individual patient data. Journal of the American Academy of Dermatology. 2019 Academic Article GET IT
Times cited: 40
Keloid lesions show increased IL-4/IL-13 signaling and respond to Th2-targeting dupilumab therapy. Journal of the European Academy of Dermatology and Venereology : JEADV. 2019 Article GET IT
Times cited: 7
Interleukin 17C is elevated in lesional tissue of hidradenitis suppurativa. The British journal of dermatology. 2019 Article GET IT
Times cited: 26
Use of Tape Strips to Detect Immune and Barrier Abnormalities in the Skin of Children With Early-Onset Atopic Dermatitis. JAMA dermatology. 2019 Academic Article GET IT
Times cited: 113
Persistence of Inflammatory Phenotype in Residual Psoriatic Plaques in Patients on Effective Biologic Therapy. The Journal of investigative dermatology. 2019 Academic Article GET IT
Times cited: 3
Early Quantification of Systemic Inflammatory Proteins Predicts Long-Term Treatment Response to Tofacitinib and Etanercept. The Journal of investigative dermatology. 2019 Academic Article GET IT
Times cited: 5
The proteomic skin profile of moderate-to-severe atopic dermatitis patients shows an inflammatory signature. Journal of the American Academy of Dermatology. 2019 Academic Article GET IT
Times cited: 35
Evolution of pathologic T-cell subsets in patients with atopic dermatitis from infancy to adulthood. The Journal of allergy and clinical immunology. 2019 Academic Article GET IT
Times cited: 67
Increased cardiovascular and atherosclerosis markers in blood of older patients with atopic dermatitis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2019 Academic Article GET IT
Times cited: 26
Cutaneous p38 mitogen-activated protein kinase activation triggers psoriatic dermatitis. The Journal of allergy and clinical immunology. 2019 Academic Article GET IT
Times cited: 11
Oral Janus kinase/SYK inhibition (ASN002) suppresses inflammation and improves epidermal barrier markers in patients with atopic dermatitis. The Journal of allergy and clinical immunology. 2019 Academic Article GET IT
Times cited: 36
Risankizumab compared with adalimumab in patients with moderate-to-severe plaque psoriasis (IMMvent): a randomised, double-blind, active-comparator-controlled phase 3 trial. Lancet (London, England). 2019 Academic Article GET IT
Times cited: 83
IL-4Rα Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis. The Journal of investigative dermatology. 2019 Academic Article GET IT
Times cited: 139
IL-17A inhibition by secukinumab induces early clinical, histopathologic, and molecular resolution of psoriasis. The Journal of allergy and clinical immunology. 2019 Academic Article GET IT
Times cited: 31
Inter-rater reliability of phenotypes and exploratory genotype-phenotype analysis in inherited hidradenitis suppurativa. The British journal of dermatology. 2019 Academic Article GET IT
Times cited: 38
The blood proteomic signature of early-onset pediatric atopic dermatitis shows systemic inflammation and is distinct from adult long-standing disease. Journal of the American Academy of Dermatology. 2019 Academic Article GET IT
Times cited: 37
The skin as an immune organ: Tolerance versus effector responses and applications to food allergy and hypersensitivity reactions. The Journal of allergy and clinical immunology. 2019 Academic Article GET IT
Times cited: 14
Inflammasome Signaling and Impaired Vascular Health in Psoriasis. Arteriosclerosis, thrombosis, and vascular biology. 2019 Academic Article GET IT
Times cited: 64
A randomized, double-blind, placebo-controlled phase 1 study of multiple ascending doses of subcutaneous M1095, an anti-interleukin 17A/F nanobody, in moderate-to-severe psoriasis. Journal of the American Academy of Dermatology. 2019 Academic Article GET IT
Times cited: 19
Topical, systemic and biologic therapies in hidradenitis suppurativa: pathogenic insights by examining therapeutic mechanisms. Therapeutic advances in chronic disease. 2019 Information Resource GET IT
Times cited: 42
The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis. Rheumatology (Oxford, England). 2019 Information Resource GET IT
Times cited: 70
Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. The Journal of allergy and clinical immunology. 2019 Academic Article GET IT
Times cited: 40
Hyperspectral imaging in automated digital dermoscopy screening for melanoma. Lasers in surgery and medicine. 2019 Academic Article GET IT
Times cited: 27
Atopic dermatitis endotypes and implications for targeted therapeutics. The Journal of allergy and clinical immunology. 2019 Information Resource GET IT
Times cited: 65
Novel immune signatures associated with dysplastic naevi and primary cutaneous melanoma in human skin. Experimental dermatology. 2018 Academic Article GET IT
Times cited: 16
Psoriatic skin molecular and histopathologic profiles after treatment with risankizumab versus ustekinumab. The Journal of allergy and clinical immunology. 2018 Academic Article GET IT
Times cited: 26
Blood endotyping distinguishes the profile of vitiligo from that of other inflammatory and autoimmune skin diseases. The Journal of allergy and clinical immunology. 2018 Academic Article GET IT
Times cited: 18
Distinct transcriptomic profiles of early-onset atopic dermatitis in blood and skin of pediatric patients. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2018 Academic Article GET IT
Times cited: 15
Impact of Zostavax Vaccination on T-Cell Accumulation and Cutaneous Gene Expression in the Skin of Older Humans After Varicella Zoster Virus Antigen-Specific Challenge. The Journal of infectious diseases. 2018 Academic Article GET IT
Times cited: 11
Atopic dermatitis in African American patients is T_H2/T_H22-skewed with T_H1/T_H17 attenuation. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2018 Academic Article GET IT
Times cited: 67
Skin resident memory CD8⁺ T cells are phenotypically and functionally distinct from circulating populations and lack immediate cytotoxic function. Clinical and experimental immunology. 2018 Academic Article GET IT
Times cited: 24
Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis. The Journal of allergy and clinical immunology. 2018 Academic Article GET IT
Times cited: 169
Baseline IL-22 expression in patients with atopic dermatitis stratifies tissue responses to fezakinumab. The Journal of allergy and clinical immunology. 2018 Academic Article GET IT
Times cited: 65
The human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses. The Journal of experimental medicine. 2018 Academic Article GET IT
Times cited: 90
IL-17C: A Unique Epithelial Cytokine with Potential for Targeting across the Spectrum of Atopic Dermatitis and Psoriasis. The Journal of investigative dermatology. 2018 Article GET IT
Times cited: 33
Ichthyosis molecular fingerprinting shows profound T_H17 skewing and a unique barrier genomic signature. The Journal of allergy and clinical immunology. 2018 Academic Article GET IT
Times cited: 73
Early-onset pediatric atopic dermatitis is characterized by T_H2/T_H17/T_H22-centered inflammation and lipid alterations. The Journal of allergy and clinical immunology. 2018 Academic Article GET IT
Times cited: 91
The Major Orphan Forms of Ichthyosis Are Characterized by Systemic T-Cell Activation and Th-17/Tc-17/Th-22/Tc-22 Polarization in Blood. The Journal of investigative dermatology. 2018 Academic Article GET IT
Times cited: 17
Interleukin 23 in the skin: role in psoriasis pathogenesis and selective interleukin 23 blockade as treatment. Therapeutic advances in chronic disease. 2018 Academic Article GET IT
Times cited: 81
The Rockefeller University Clinical Scholars (KL2) Program 2006-2016. Journal of clinical and translational science. 2018 Academic Article GET IT
Efficacy and safety of fezakinumab (an IL-22 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by conventional treatments: A randomized, double-blind, phase 2a trial. Journal of the American Academy of Dermatology. 2018 Academic Article GET IT
Times cited: 138
Interleukin-17 alters the biology of many cell types involved in the genesis of psoriasis, systemic inflammation and associated comorbidities. Experimental dermatology. 2017 Information Resource GET IT
Times cited: 63
Alopecia areata is characterized by expansion of circulating Th2/Tc2/Th22, within the skin-homing and systemic T-cell populations. Allergy. 2017 Academic Article GET IT
Times cited: 26
Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase-induced inflammation. The Journal of allergy and clinical immunology. 2017 Academic Article GET IT
Times cited: 69
Dust mite induces multiple polar T cell axes in human skin. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2017 Academic Article GET IT
Times cited: 15
Clinically resolved psoriatic lesions contain psoriasis-specific IL-17-producing αβ T cell clones. The Journal of clinical investigation. 2017 Academic Article GET IT
Times cited: 194
Reduction of Inflammatory and Cardiovascular Proteins in the Blood of Patients with Psoriasis: Differential Responses between Tofacitinib and Etanercept after 4 Weeks of Treatment. The Journal of investigative dermatology. 2017 Academic Article GET IT
Times cited: 20
Atopic dermatitis and psoriasis: two different immune diseases or one spectrum?. Current opinion in immunology. 2017 Information Resource GET IT
Times cited: 138
Psoriasis pathogenesis and the development of novel targeted immune therapies. The Journal of allergy and clinical immunology. 2017 Information Resource GET IT
Times cited: 599
The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteins. Scientific reports. 2017 Academic Article GET IT
Identification of unique proteomic signatures in allergic and non-allergic skin disease. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2017 Academic Article GET IT
Times cited: 28
Line scanning, stage scanning confocal microscope (LSSSCM). Biomedical optics express. 2017 Academic Article GET IT
Times cited: 14
Autoantigens ADAMTSL5 and LL37 are significantly upregulated in active Psoriasis and localized with keratinocytes, dendritic cells and other leukocytes. Experimental dermatology. 2017 Academic Article GET IT
Times cited: 79
IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment. Cell. 2017 Academic Article GET IT
Times cited: 125
Nonlesional atopic dermatitis skin shares similar T-cell clones with lesional tissues. Allergy. 2017 Academic Article GET IT
Times cited: 35
Novel concepts of prevention and treatment of atopic dermatitis through barrier and immune manipulations with implications for the atopic march. The Journal of allergy and clinical immunology. 2017 Information Resource GET IT
Times cited: 126
The management of moderate-to-severe chronic plaque psoriasis. Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia. 2017 Information Resource GET IT
Times cited: 1
Systemic immune mechanisms in atopic dermatitis and psoriasis with implications for treatment. Experimental dermatology. 2017 Information Resource GET IT
Times cited: 82
Risankizumab versus Ustekinumab for Moderate-to-Severe Plaque Psoriasis. The New England journal of medicine. 2017 Academic Article GET IT
Times cited: 257
Cutting Edge: Selective Oral ROCK2 Inhibitor Reduces Clinical Scores in Patients with Psoriasis Vulgaris and Normalizes Skin Pathology via Concurrent Regulation of IL-17 and IL-10. Journal of immunology (Baltimore, Md. : 1950). 2017 Academic Article GET IT
Times cited: 63
TNF-α Antagonist and Vascular Inflammation in Patients with Psoriasis Vulgaris: A Randomized Placebo-Controlled Study. The Journal of investigative dermatology. 2017 Academic Article GET IT
Times cited: 57
Aberrant connective tissue differentiation towards cartilage and bone underlies human keloids in African Americans. Experimental dermatology. 2017 Academic Article GET IT
Times cited: 24
Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism. Nature. 2017 Academic Article GET IT
Times cited: 472
Patch testing of food allergens promotes Th17 and Th2 responses with increased IL-33: a pilot study. Experimental dermatology. 2017 Article GET IT
Times cited: 8
Digital imaging biomarkers feed machine learning for melanoma screening. Experimental dermatology. 2016 Article GET IT
Times cited: 23
Alterations in B-cell subsets in pediatric patients with early atopic dermatitis. The Journal of allergy and clinical immunology. 2016 Academic Article GET IT
Times cited: 33
An Integrated Model of Atopic Dermatitis Biomarkers Highlights the Systemic Nature of the Disease. The Journal of investigative dermatology. 2016 Academic Article GET IT
Times cited: 86
Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling. The Journal of allergy and clinical immunology. 2016 Academic Article GET IT
Times cited: 66
Palmoplantar pustular psoriasis (PPPP) is characterized by activation of the IL-17A pathway. Journal of dermatological science. 2016 Academic Article GET IT
Times cited: 16
Shrinking the Psoriasis Assessment Gap: Early Gene-Expression Profiling Accurately Predicts Response to Long-Term Treatment. The Journal of investigative dermatology. 2016 Academic Article GET IT
Times cited: 26
Cutaneous Expression of A Disintegrin-like and Metalloprotease domain containing Thrombospondin Type 1 motif-like 5 (ADAMTSL5) in Psoriasis goes beyond Melanocytes. Journal of pigmentary disorders. 2016 Academic Article GET IT
An IL-17-dominant immune profile is shared across the major orphan forms of ichthyosis. The Journal of allergy and clinical immunology. 2016 Academic Article GET IT
Efficacy and safety of ustekinumab treatment in adults with moderate-to-severe atopic dermatitis. Experimental dermatology. 2016 Academic Article GET IT
Definite regression of cutaneous melanoma metastases upon addition of topical contact sensitizer diphencyprone to immune checkpoint inhibitor treatment. Experimental dermatology. 2016 Article GET IT
Times cited: 16
Discrimination of Dysplastic Nevi from Common Melanocytic Nevi by Cellular and Molecular Criteria. The Journal of investigative dermatology. 2016 Academic Article GET IT
Times cited: 13
A prospective phase III, randomized, double-blind, placebo-controlled study of brodalumab in patients with moderate-to-severe plaque psoriasis. The British journal of dermatology. 2016 Academic Article GET IT
Times cited: 263
Cyclosporine A immunosuppression drives catastrophic squamous cell carcinoma through IL-22. JCI insight. 2016 Academic Article GET IT
Cutaneous Adverse Events in the Randomized, Double-Blind, Active-Comparator DECIDE Study of Daclizumab High-Yield Process Versus Intramuscular Interferon Beta-1a in Relapsing-Remitting Multiple Sclerosis. Advances in therapy. 2016 Academic Article GET IT
Times cited: 30
Lipoprotein Metabolism and Inflammation in Patients With Psoriasis. The American journal of cardiology. 2016 Information Resource GET IT
Times cited: 16
The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes. The Journal of investigative dermatology. 2016 Academic Article GET IT
Times cited: 28
Based on Molecular Profiling of Gene Expression, Palmoplantar Pustulosis and Palmoplantar Pustular Psoriasis Are Highly Related Diseases that Appear to Be Distinct from Psoriasis Vulgaris. PloS one. 2016 Academic Article GET IT
Times cited: 41
IL-32 induces indoleamine 2,3-dioxygenase⁺CD1c⁺ dendritic cells and indoleamine 2,3-dioxygenase⁺CD163⁺ macrophages: Relevance to mycosis fungoides progression. Oncoimmunology. 2016 Academic Article GET IT
Times cited: 24
Efficacy of Tofacitinib for the Treatment of Moderate-to-Severe Chronic Plaque Psoriasis in Patient Subgroups from Two Randomised Phase 3 Trials. Journal of drugs in dermatology : JDD. 2016 Academic Article GET IT
Times cited: 17
New therapies for psoriasis and psoriatic arthritis. Current opinion in rheumatology. 2016 Information Resource GET IT
Times cited: 57
Reply. The Journal of allergy and clinical immunology. 2016 Article GET IT
Tofacitinib attenuates pathologic immune pathways in patients with psoriasis: A randomized phase 2 study. The Journal of allergy and clinical immunology. 2016 Academic Article GET IT
Times cited: 81
Methotrexate improves pro- and anti-atherogenic genomic expression in psoriatic skin. Journal of dermatological science. 2016 Article GET IT
Times cited: 3
Biomarkers of alopecia areata disease activity and response to corticosteroid treatment. Experimental dermatology. 2016 Academic Article GET IT
Times cited: 40
A mild topical steroid leads to progressive anti-inflammatory effects in the skin of patients with moderate-to-severe atopic dermatitis. The Journal of allergy and clinical immunology. 2016 Academic Article GET IT
Tofacitinib, an oral Janus kinase inhibitor, for the treatment of chronic plaque psoriasis: Long-term efficacy and safety results from 2 randomized phase-III studies and 1 open-label long-term extension study. Journal of the American Academy of Dermatology. 2016 Academic Article GET IT
Times cited: 90
Molecular and Cellular Profiling of Scalp Psoriasis Reveals Differences and Similarities Compared to Skin Psoriasis. PloS one. 2016 Academic Article GET IT
Times cited: 35
Molecular Phenotyping Small (Asian) versus Large (Western) Plaque Psoriasis Shows Common Activation of IL-17 Pathway Genes but Different Regulatory Gene Sets. The Journal of investigative dermatology. 2016 Academic Article GET IT
Times cited: 48
The tryptophan metabolism enzyme L-kynureninase is a novel inflammatory factor in psoriasis and other inflammatory diseases. The Journal of allergy and clinical immunology. 2015 Academic Article GET IT
Times cited: 103
An autoimmune "attack" on melanocytes triggers psoriasis and cellular hyperplasia. The Journal of experimental medicine. 2015 Article GET IT
Times cited: 21
A Randomized, Placebo-Controlled Study of SRT2104, a SIRT1 Activator, in Patients with Moderate to Severe Psoriasis. PloS one. 2015 Academic Article GET IT
Times cited: 73
Tildrakizumab (MK-3222), an anti-interleukin-23p19 monoclonal antibody, improves psoriasis in a phase IIb randomized placebo-controlled trial. The British journal of dermatology. 2015 Academic Article GET IT
Times cited: 183
Reply: To PMID 25748064. The Journal of allergy and clinical immunology. 2015 Article GET IT
TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL. Science translational medicine. 2015 Academic Article GET IT
Times cited: 154
Diverse activation and differentiation of multiple B-cell subsets in patients with atopic dermatitis but not in patients with psoriasis. The Journal of allergy and clinical immunology. 2015 Academic Article GET IT
Times cited: 70
Petrolatum: Barrier repair and antimicrobial responses underlying this "inert" moisturizer. The Journal of allergy and clinical immunology. 2015 Academic Article GET IT
Times cited: 84
The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization. The Journal of allergy and clinical immunology. 2015 Academic Article GET IT
Times cited: 276
Unique microRNAs appear at different times during the course of a delayed-type hypersensitivity reaction in human skin. Experimental dermatology. 2015 Academic Article GET IT
Times cited: 17
Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing. The Journal of allergy and clinical immunology. 2015 Academic Article GET IT
Times cited: 114
First-In-Human, Phase 1, Randomized, Dose-Escalation Trial with Recombinant Anti-IL-20 Monoclonal Antibody in Patients with Psoriasis. PloS one. 2015 Academic Article GET IT
Times cited: 19
Deep Sequencing of the T-cell Receptor Repertoire Demonstrates Polyclonal T-cell Infiltrates in Psoriasis. F1000Research. 2015 Academic Article GET IT
Times cited: 38
CCL20 and IL22 Messenger RNA Expression After Adalimumab vs Methotrexate Treatment of Psoriasis: A Randomized Clinical Trial. JAMA dermatology. 2015 Academic Article GET IT
Times cited: 41
Early pediatric atopic dermatitis shows only a cutaneous lymphocyte antigen (CLA)(+) TH2/TH1 cell imbalance, whereas adults acquire CLA(+) TH22/TC22 cell subsets. The Journal of allergy and clinical immunology. 2015 Academic Article GET IT
Times cited: 166
The immunogenetics of Psoriasis: A comprehensive review. Journal of autoimmunity. 2015 Information Resource GET IT
Times cited: 404
Histological Stratification of Thick and Thin Plaque Psoriasis Explores Molecular Phenotypes with Clinical Implications. PloS one. 2015 Academic Article GET IT
Times cited: 21
A phase 2a randomized, double-blind, placebo-controlled, sequential dose-escalation study to evaluate the efficacy and safety of ASP015K, a novel Janus kinase inhibitor, in patients with moderate-to-severe psoriasis. The British journal of dermatology. 2015 Academic Article GET IT
Times cited: 57
Psoriasis is characterized by deficient negative immune regulation compared to transient delayed-type hypersensitivity reactions. F1000Research. 2015 Academic Article GET IT
Times cited: 12
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The Characterization of Varicella Zoster Virus-Specific T Cells in Skin and Blood during Aging. The Journal of investigative dermatology. 2015 Academic Article GET IT
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Laser capture microdissection followed by next-generation sequencing identifies disease-related microRNAs in psoriatic skin that reflect systemic microRNA changes in psoriasis. Experimental dermatology. 2015 Academic Article GET IT
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Patients with atopic dermatitis have attenuated and distinct contact hypersensitivity responses to common allergens in skin. The Journal of allergy and clinical immunology. 2015 Academic Article GET IT
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Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis. The Journal of allergy and clinical immunology. 2014 Academic Article GET IT
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Accumulating evidence for the association and shared pathogenic mechanisms between psoriasis and cardiovascular-related comorbidities. The American journal of medicine. 2014 Information Resource GET IT
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Cyclosporine in patients with atopic dermatitis modulates activated inflammatory pathways and reverses epidermal pathology. The Journal of allergy and clinical immunology. 2014 Academic Article GET IT
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Molecular characterization of human skin response to diphencyprone at peak and resolution phases: therapeutic insights. The Journal of investigative dermatology. 2014 Academic Article GET IT
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Guselkumab (an IL-23-specific mAb) demonstrates clinical and molecular response in patients with moderate-to-severe psoriasis. The Journal of allergy and clinical immunology. 2014 Academic Article GET IT
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Gene expression profiles normalized in psoriatic skin by treatment with brodalumab, a human anti-IL-17 receptor monoclonal antibody. Journal of immunology (Baltimore, Md. : 1950). 2014 Academic Article GET IT
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Suppression of molecular inflammatory pathways by Toll-like receptor 7, 8, and 9 antagonists in a model of IL-23-induced skin inflammation. PloS one. 2013 Academic Article GET IT
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Gene expression profiling of the leading edge of cutaneous squamous cell carcinoma: IL-24-driven MMP-7. The Journal of investigative dermatology. 2013 Academic Article GET IT
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An animal explant model for the study of human cutaneous squamous cell carcinoma. PloS one. 2013 Academic Article GET IT
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Gene profiling of narrowband UVB-induced skin injury defines cellular and molecular innate immune responses. The Journal of investigative dermatology. 2012 Academic Article GET IT
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IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis. The Journal of allergy and clinical immunology. 2012 Academic Article GET IT
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Anti-IL-17 receptor antibody AMG 827 leads to rapid clinical response in subjects with moderate to severe psoriasis: results from a phase I, randomized, placebo-controlled trial. The Journal of investigative dermatology. 2012 Article GET IT
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Anti-cytokine therapies for psoriasis. Experimental cell research. 2011 Information Resource GET IT
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A novel chimeric lysin shows superiority to mupirocin for skin decolonization of methicillin-resistant and -sensitive Staphylococcus aureus strains. Antimicrobial agents and chemotherapy. 2010 Academic Article GET IT
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Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes. The Journal of allergy and clinical immunology. 2009 Academic Article GET IT
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Double-blind, placebo-controlled, dose-escalation study to evaluate the pharmacologic effect of CP-690,550 in patients with psoriasis. The Journal of investigative dermatology. 2009 Article GET IT
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Combining several ordinal measures in clinical studies. Statistics in medicine. 2004 Academic Article GET IT
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Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells. The Journal of experimental medicine. 2000 Academic Article GET IT
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Successful in vivo blockade of CD25 (high-affinity interleukin 2 receptor) on T cells by administration of humanized anti-Tac antibody to patients with psoriasis. Journal of the American Academy of Dermatology. 2000 Academic Article GET IT
Anti-CD11a treatment for psoriasis concurrently increases circulating T-cells and decreases plaque T-cells, consistent with inhibition of cutaneous T-cell trafficking. The Journal of investigative dermatology. 2000 Academic Article GET IT
Two considerations for patients with psoriasis and their clinicians: what defines mild, moderate, and severe psoriasis? What constitutes a clinically significant improvement when treating psoriasis?. Journal of the American Academy of Dermatology. 2000 Academic Article GET IT
Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis. Journal of the American Academy of Dermatology. 2000 Academic Article GET IT
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CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: blood and skin comparisons by flow cytometry. Journal of autoimmunity. 2000 Academic Article GET IT
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Clinical clearing of psoriasis by 6-thioguanine correlates with cutaneous T-cell depletion via apoptosis: evidence for selective effects on activated T lymphocytes. Archives of dermatology. 1999 Academic Article GET IT
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Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions. The Journal of clinical investigation. 1999 Academic Article GET IT
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Identification of a novel keratinocyte mitogen derived from bovine pituitary glands. Archives of dermatological research. 1997 Academic Article GET IT
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Identification of aberrantly regulated genes in diseased skin using the cDNA differential display technique. The Journal of investigative dermatology. 1997 Academic Article GET IT
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GM-CSF activates regenerative epidermal growth and stimulates keratinocyte proliferation in human skin in vivo. The Journal of investigative dermatology. 1994 Academic Article GET IT
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Studies of the effect of cyclosporine in psoriasis in vivo: combined effects on activated T lymphocytes and epidermal regenerative maturation. The Journal of investigative dermatology. 1992 Academic Article GET IT
Times cited: 94
Role of T cell activation in the pathogenesis of psoriasis. Annals of the New York Academy of Sciences. 1991 Academic Article GET IT
Times cited: 9
Junctional epidermolysis bullosa keratinocytes in culture display adhesive, structural, and functional abnormalities. The Journal of investigative dermatology. 1991 Academic Article GET IT
Times cited: 14
Detection of cytokine-induced protein gamma-immune protein-10 (gamma-IP10) in atypical melanocytic proliferations. Journal of the American Academy of Dermatology. 1991 Academic Article GET IT
Times cited: 9
HMB-45 monoclonal antibody recognizes an inducible and reversible melanocyte cytoplasmic protein. Journal of cutaneous pathology. 1991 Academic Article GET IT
Times cited: 45
Cyclosporine in psoriasis treatment. Inhibition of keratinocyte cell-cycle progression in G1 independent of effects on transforming growth factor alpha/epidermal growth factor receptor pathways. Archives of dermatology. 1991 Academic Article GET IT
Times cited: 39
Differential expression of p62c-yes in normal, hyperplastic and neoplastic human epidermis. Oncogene. 1991 Academic Article GET IT
Times cited: 20
Increased dermal expression of platelet-derived growth factor receptors in growth-activated skin wounds and psoriasis. The Journal of investigative dermatology. 1991 Academic Article GET IT
Times cited: 46
Tigliane-type phorbols stimulate human melanocyte proliferation: potentially safer agents for melanocyte culture. The Journal of investigative dermatology. 1991 Academic Article GET IT
Synergistic effects of epidermal growth factor (EGF) and insulin-like growth factor I/somatomedin C (IGF-I) on keratinocyte proliferation may be mediated by IGF-I transmodulation of the EGF receptor. The Journal of investigative dermatology. 1991 Academic Article GET IT
Times cited: 109
Fixed drug eruptions: evidence for a cytokine-mediated process. Journal of cutaneous pathology. 1991 Academic Article GET IT
Times cited: 19
TGF-alpha and TGF-beta expression during sodium-N-butyrate-induced differentiation of human keratinocytes: evidence for subpopulation-specific up-regulation of TGF-beta mRNA in suprabasal cells. Experimental cell research. 1990 Academic Article GET IT
Times cited: 19
Detection of the interferon-gamma-induced protein 10 in psoriasiform dermatitis of acquired immunodeficiency syndrome. Archives of dermatology. 1990 Academic Article GET IT
Times cited: 22
Expression of cellular-yes protein in mammalian tissues. Oncogene. 1990 Academic Article GET IT
Times cited: 76
"Activated" keratinocyte phenotype is unifying feature in conditions which predispose to squamous cell carcinoma of the skin. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 1990 Academic Article GET IT
Times cited: 18
Recessive dystrophic epidermolysis bullosa skin displays a chronic growth-activated immunophenotype. Implications for carcinogenesis. Archives of dermatology. 1990 Academic Article GET IT
Times cited: 38
Interleukin 6 decreases cell-cell association and increases motility of ductal breast carcinoma cells. The Journal of experimental medicine. 1989 Academic Article GET IT
Times cited: 165
Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes. Proceedings of the National Academy of Sciences of the United States of America. 1989 Academic Article GET IT
Times cited: 791
Application of a unique monoclonal antibody as a marker for nonproliferating subpopulations of cells of some tissue. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 1985 Academic Article GET IT
Times cited: 52
Size-variant pp60src proteins of recovered avian sarcoma viruses interact with adhesion plaques as peripheral membrane proteins: effects on cell transformation. Molecular and cellular biology. 1984 Academic Article GET IT
Times cited: 23
Temperature-sensitive membrane association of pp60src in tsNY68-infected cells correlates with increased tyrosine phosphorylation of membrane-associated proteins. Virology. 1983 Academic Article GET IT
Times cited: 7
Only membrane-associated RSV src proteins have amino-terminally bound lipid. Nature. 1983 Academic Article GET IT
Times cited: 29
Novel localization of pp60src in Rous sarcoma virus-transformed rat and goat cells and in chicken cells transformed by viruses rescued from these mammalian cells. Virology. 1982 Academic Article GET IT
Times cited: 12
Changes in amino-terminal sequences of pp60src lead to decreased membrane association and decreased in vivo tumorigenicity. Cell. 1982 Academic Article GET IT
Times cited: 44
Differences in intracellular location of pp60src in rat and chicken cells transformed by Rous sarcoma virus. Proceedings of the National Academy of Sciences of the United States of America. 1980 Academic Article GET IT
Times cited: 46
Evidence that the src gene product of Rous sarcoma virus is membrane associated. Virology. 1980 Academic Article GET IT
Times cited: 79
Localization and characterization of the src-gene product of Rous sarcoma virus. Cold Spring Harbor symposia on quantitative biology. 1980 Academic Article GET IT
Times cited: 6

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Background

education and training

A.B., Princeton University 79
M.D., Cornell University Medical College 1985
Ph.D., The Rockefeller University 1984

Contact

full name

James Glenn Krueger

VIVO Weill Cornell Medical College

James Glenn Krueger Adjunct Assistant Professor of Dermatology

Publications

selected publications

Background

education and training

Contact

full name