Selected publications
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Dose, schedule, safety, and efficacy of guadecitabine in relapsed or refractory acute myeloid leukemia.
Cancer.
2018
Academic Article
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Times cited: 1 - Validation of a post-hypomethylating agent failure prognostic model in myelodysplastic syndromes patients treated in a randomized controlled phase III trial of rigosertib vs. Best supportive care. Blood Cancer Journal. 2017 Information Resource GET IT
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Guadecitabine (SGI-110) in treatment-naive patients with acute myeloid leukaemia: Phase 2 results from a multicentre, randomised, phase 1/2 trial.
The lancet oncology.
2017
Academic Article
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Times cited: 6 -
Phase 2, randomized, double-blind study of pracinostat in combination with azacitidine in patients with untreated, higher risk myelodysplastic syndromes.
Cancer.
2017
Academic Article
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Times cited: 10 - Randomized phase 2 study of low-dose decitabine vs low-dose azacitidine in lower-risk MDS and MDS/MPN. Blood. 2017 Academic Article GET IT
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Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia.
Blood.
2017
Academic Article
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Times cited: 48 - Practical implications of the 2016 revision of the world health organization classification of lymphoid and myeloid neoplasms and acute leukemia. Journal of Clinical Oncology. 2017 Review GET IT
- Selection and characterization of antibody clones are critical for accurate flow cytometry-based monitoring of CD123 in acute myeloid leukemia. Leukemia and Lymphoma. 2017 Academic Article GET IT
- CD25 expression and outcomes in older patients with acute myelogenous leukemia treated with plerixafor and decitabine. Leukemia and Lymphoma. 2017 Academic Article GET IT
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The effect of initial molecular profile on response to recombinant interferon-α (rIFNα) treatment in early myelofibrosis.
Cancer.
2017
Academic Article
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Times cited: 5 -
Minimal Residual Disease Monitoring of Acute Myeloid Leukemia by Massively Multiplex Digital PCR in Patients with NPM1 Mutations.
Journal of Molecular Diagnostics.
2017
Academic Article
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Times cited: 5 -
Comparison of clinical outcomes and prognostic utility of risk stratification tools in patients with therapy-related vs de novo myelodysplastic syndromes: A report on behalf of the MDS Clinical Research Consortium.
Leukemia.
2017
Academic Article
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Times cited: 6 -
Outcome of lower-risk patients with myelodysplastic syndromes without 5q deletion after failure of erythropoiesis-stimulating agents.
Journal of Clinical Oncology.
2017
Academic Article
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Times cited: 5 -
Differential response to hypomethylating agents based on sex: a report on behalf of the MDS Clinical Research Consortium (MDS CRC)*.
Leukemia and Lymphoma.
2016
Academic Article
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Times cited: 2 - The application of mass spectrometry to leukemia drug discovery. Expert Opinion on Drug Discovery. 2016 Academic Article GET IT
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A multi-institution phase i trial of ruxolitinib in patients with chronic myelomonocytic leukemia (CMML).
Clinical Cancer Research.
2016
Academic Article
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Times cited: 23 - Are we ready for precision medicine in acute myeloid leukemia?. Clinical Advances in Hematology and Oncology. 2016 Article GET IT
- Are we ready for precision medicine in acute myeloid leukemia?. Clinical Advances in Hematology and Oncology. 2016 Comment
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Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Nature Medicine.
2016
Academic Article
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Times cited: 52 -
The efficacy of current prognostic models in predicting outcome of patients with myelodysplastic syndromes at the time of hypomethylating agent failure.
Haematologica.
2016
Article
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Times cited: 10 - Clofarabine as a bridge to hematopoietic stem cell transplant. Leukemia and Lymphoma. 2016 Article GET IT
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Allogeneic Transplantation for Patients with Advanced Myelofibrosis: Splenomegaly and High Serum LDH are Adverse Risk Factors for Successful Engraftment.
Clinical Lymphoma, Myeloma and Leukemia.
2016
Academic Article
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Times cited: 2 -
Comparison of risk stratification tools in predicting outcomes of patients with higher-risk myelodysplastic syndromes treated with azanucleosides.
Leukemia.
2016
Academic Article
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Times cited: 18 -
MSI2 is required for maintaining activated myelodysplastic syndrome stem cells.
Nature Communications.
2016
Academic Article
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Times cited: 8 -
Design of the randomized, Phase III, QUAZAR AML Maintenance trial of CC-486 (oral azacitidine) maintenance therapy in acute myeloid leukemia.
Future Oncology.
2016
Academic Article
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Times cited: 4 -
Outcomes of patients with myelodysplastic syndromes who achieve stable disease after treatment with hypomethylating agents.
Leukemia Research.
2016
Academic Article
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Times cited: 5 -
Rigosertib versus best supportive care for patients with high-risk myelodysplastic syndromes after failure of hypomethylating drugs (ONTIME): A randomised, controlled, phase 3 trial.
The lancet oncology.
2016
Academic Article
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Times cited: 35 -
The epichaperome is an integrated chaperome network that facilitates tumour survival.
Nature.
2016
Academic Article
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Times cited: 26 -
In vivo targeting of leukemia stem cells by directing parthenolide-loaded nanoparticles to the bone marrow niche.
Leukemia.
2015
Article
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Times cited: 6 -
A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species.
Cell Reports.
2015
Academic Article
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Times cited: 9 -
Comparing the prognostic value of risk stratifying models for patients with lower-risk myelodysplastic syndromes: Is one model better?.
American Journal of Hematology.
2015
Academic Article
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Times cited: 9 - Evolving treatments in acute myeloid leukemia. Clinical Advances in Hematology and Oncology. 2015 Academic Article
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Phase I dose escalation study of lestaurtinib in patients with myelofibrosis.
Leukemia and Lymphoma.
2015
Academic Article
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Times cited: 9 -
Phase i trial of SAR103168, a novel multi-kinase inhibitor, in patients with refractory/relapsed acute leukemia or high-risk myelodysplastic syndrome.
Leukemia and Lymphoma.
2015
Academic Article
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Times cited: 2 -
Safety and tolerability of guadecitabine (SGI-110) in patients with myelodysplastic syndrome and acute myeloid leukaemia: A multicentre, randomised, dose-escalation phase 1 study.
The lancet oncology.
2015
Academic Article
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Times cited: 84 - Single-cell mass cytometry reveals intracellular survival/proliferative signaling in FLT3-ITD-mutated AML stem/progenitor cells. Cytometry Part A. 2015 Academic Article GET IT
- Single-cell mass cytometry reveals intracellular survival/proliferative signaling in FLT3-ITD-mutated AML stem/progenitor cells. Cytometry Part A. 2015 Academic Article GET IT
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Vosaroxin plus cytarabine versus placebo plus cytarabine in patients with first relapsed or refractory acute myeloid leukaemia (VALOR): A randomised, controlled, double-blind, multinational, phase 3 study.
The lancet oncology.
2015
Academic Article
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Times cited: 53 -
Prevalence, management, and clinical consequences of QT interval prolongation during treatment with arsenic trioxide.
Journal of Clinical Oncology.
2014
Academic Article
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Times cited: 19 -
International randomized phase III study of elacytarabine versus investigator choice in patients with relapsed/refractory acute myeloid leukemia.
Journal of Clinical Oncology.
2014
Academic Article
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Times cited: 45 -
Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia.
Science Translational Medicine.
2014
Academic Article
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Times cited: 646 -
Epigenetic targeting and personalized approaches for AML.
Hematology. American Society of Hematology. Education Program.
2014
Review
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Times cited: 6 -
Open-label study of oral CEP-701 (lestaurtinib) in patients with polycythaemia vera or essential thrombocythaemia with JAK2-V617F mutation.
British Journal of Haematology.
2014
Academic Article
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Times cited: 16 -
Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: A novel potential strategy in acute myelogenous leukemia.
Molecular Cancer Therapeutics.
2014
Academic Article
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Times cited: 19 - Treating relapsed/refractory all in older patients: Case presentations. Clinical Advances in Hematology and Oncology. 2014 Comment
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Standardizing the initial evaluation for myelodysplastic syndromes.
Current Hematologic Malignancy Reports.
2013
Review
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Times cited: 2 -
Decitabine in patients with newly diagnosed and relapsed acute myeloid leukemia.
Leukemia and Lymphoma.
2013
Academic Article
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Times cited: 57 -
A Phase I Study of CPX-351 in Combination with Busulfan and Fludarabine Conditioning and Allogeneic Stem Cell Transplantation in Adult Patients with Refractory Acute Leukemia.
Biology of Blood and Marrow Transplantation.
2013
Academic Article
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Times cited: 8 -
Emergence of carbapenem-resistant Enterobacteriaceae as causes of bloodstream infections in patients with hematologic malignancies.
Leukemia and Lymphoma.
2013
Academic Article
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Times cited: 53 -
A randomized controlled trial of romiplostim in patients with low-or intermediate-risk myelodysplastic syndrome receiving decitabine.
Leukemia and Lymphoma.
2013
Academic Article
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Times cited: 38 -
Pregnancy in a woman with chronic neutrophilic leukemia.
Obstetrics and Gynecology.
2013
Academic Article
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Times cited: 1 -
Proposed criteria for response assessment in patients treated in clinical trials for myeloproliferative neoplasms in blast phase (MPN-BP): Formal recommendations from the post-myeloproliferative neoplasm acute myeloid leukemia consortium.
Leukemia Research.
2012
Review
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Times cited: 18 -
Current treatment of acute myeloid leukemia.
Current Opinion in Oncology.
2012
Review
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Times cited: 68 -
RBC-transfusion guidelines update.
Leukemia Research.
2012
Article
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Times cited: 5 -
Are low-intensity induction strategies better for older patients with acute myeloid leukemia?.
Leukemia Research.
2012
Academic Article
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Times cited: 6 -
Multi-institutional phase 2 clinical and pharmacogenomic trial of tipifarnib plus etoposide for elderly adults with newly diagnosed acute myelogenous leukemia.
Blood.
2012
Academic Article
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Times cited: 18 -
Novel approaches to the treatment of acute myeloid leukemia.
Hematology. American Society of Hematology. Education Program.
2011
Review
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Times cited: 56 -
Phase 1 study of epigenetic priming with decitabine prior to standard induction chemotherapy for patients with AML.
Blood.
2011
Academic Article
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Times cited: 70 -
Arsenic trioxide and low-dose cytarabine for patients with intermediate-2 and high-risk myelodysplastic syndrome.
Leukemia Research.
2011
Academic Article
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Times cited: 7 -
First-in-man study of CPX-351: A liposomal carrier containing cytarabine and daunorubicin in a fixed 5:1 molar ratio for the treatment of relapsed and refractory acute myeloid leukemia.
Journal of Clinical Oncology.
2011
Academic Article
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Times cited: 116 -
What are RBC-transfusion-dependence and -independence?.
Leukemia Research.
2011
Article
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Times cited: 38 -
Levels of care: Defining best supportive care in elderly patients with acute myeloid leukemia.
Current Hematologic Malignancy Reports.
2010
Review
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Times cited: 5 -
Acute myeloid leukemia stem cells: Seek and destroy.
Expert Review of Hematology.
2009
Review
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Times cited: 26 -
Complete remissions observed in acute myeloid leukemia following prolonged exposure to lintuzumab: A phase 1 trial.
Leukemia and Lymphoma.
2009
Academic Article
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Times cited: 29 -
A pharmacodynamic study of the FLT3 inhibitor KW-2449 yields insight into the basis for clinical response.
Blood.
2009
Academic Article
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Times cited: 109 -
Active oral regimen for elderly adults with newly diagnosed acute myelogenous leukemia: A preclinical and phase 1 trial of the farnesyltransferase inhibitor tipifarnib (R115777, Zarnestra) combined with etoposide.
Blood.
2009
Academic Article
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Times cited: 47 -
Pomalidomide is active in the treatment of anemia associated with myelofibrosis.
Journal of Clinical Oncology.
2009
Academic Article
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Times cited: 156 -
Dasatinib in the treatment of chronic myeloid leukemia in accelerated phase after imatinib failure: The START a trial.
Journal of Clinical Oncology.
2009
Academic Article
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Times cited: 142 - Chemotherapy Foundation Symposium XXVI: Innovative cancer therapy for tomorrow - Voreloxin for acute myelogenous leukemia. P and T. 2008 Conference Paper
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Arsenic trioxide and low-dose cytarabine in older patients with untreated acute myeloid leukemia, excluding acute promyelocytic leukemia.
Cancer.
2008
Academic Article
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Times cited: 38 -
On the use of lonafarnib in myelodysplastic syndrome and chronic myelomonocytic leukemia.
Leukemia.
2008
Academic Article
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Times cited: 42 -
Arsenic and Old Lace: Novel Approaches in Elderly Patients With Acute Myeloid Leukemia.
Seminars in Hematology.
2008
Review
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Times cited: 5 -
Therapy-related myelodysplastic syndrome and acute myeloid leukemia following initial treatment with chemotherapy plus radioimmunotherapy for indolent non-Hodgkin lymphoma.
Leukemia Research.
2007
Academic Article
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Times cited: 15 -
Therapy-related myelodysplastic syndrome and acute myeloid leukemia following initial treatment with chemotherapy plus radioimmunotherapy for indolent non-Hodgkin lymphoma.
Leukemia Research.
2007
Academic Article
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Times cited: 8 -
PTK787/ZK 222584, a small molecule tyrosine kinase receptor inhibitor of vascular endothelial growth factor (VEGF), has modest activity in myelofibrosis with myeloid metaplasia.
Leukemia Research.
2007
Academic Article
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Times cited: 19 -
Dasatinib induces significant hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in accelerated phase.
Blood.
2007
Academic Article
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Times cited: 302 -
Treatment of acute myeloid leukemia in older patients.
Expert Review of Anticancer Therapy.
2007
Review
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Times cited: 21 -
Cloretazine (VNP40101M), a novel sulfonylhydrazine alkylating agent, in patients age 60 years or older with previously untreated acute myeloid leukemia.
Journal of Clinical Oncology.
2007
Academic Article
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Times cited: 66 -
Phase I/II study of continuous-infusion troxacitabine in refractory acute myeloid leukemia.
Journal of Clinical Oncology.
2007
Academic Article
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Times cited: 20 -
A phase II study of cloretazine (VNP40101M), a novel sulfonylhydrazine alkylating agent, in patients with very high risk relapsed acute myeloid leukemia.
Leukemia Research.
2006
Article
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Times cited: 24 - Treatment strategies for acute myeloid leukemia and myelodysplastic syndromes in the elderly population. P and T. 2006 Conference Paper
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Phase I study of bryostatin 1 and fludarabine in patients with chronic lymphocytic leukemia and indolent (non-Hodgkin's) lymphoma.
Clinical Cancer Research.
2006
Academic Article
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Times cited: 38 -
A Study of a Reduced-Intensity Conditioning Regimen Followed by Allogeneic Stem Cell Transplantation for Patients with Hematologic Malignancies Using Campath-1H as Part of a Graft-versus-Host Disease Strategy.
Biology of Blood and Marrow Transplantation.
2006
Academic Article
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Times cited: 8 -
Phase 1 study of PTK787/ZK 222584, a small molecule tyrosine kinase receptor inhibitor, for the treatment of acute myeloid leukemia and myelodysplastic syndrome.
Leukemia.
2006
Academic Article
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Times cited: 69 -
Phase III randomized multicenter study of a humanized anti-CD33 monoclonal antibody, lintuzumab, in combination with chemotherapy, versus chemotherapy alone in patients with refractory or first-relapsed acute myeloid leukemia.
Journal of Clinical Oncology.
2005
Academic Article
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Times cited: 130 -
Phase II study of troxacitabine, a novel dioxolane nucleoside analog, in patients with untreated or imatinib mesylate-resistant chronic myelogenous leukemia in blastic phase.
Leukemia Research.
2003
Academic Article
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Times cited: 20 -
The emergence of Ph-, trisomy -8+ cells in patients with chronic myeloid leukemia treated with imatinib mesylate.
Experimental Hematology.
2003
Academic Article
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Times cited: 36 -
Efficacy and safety of gemtuzumab ozogamicin in patients with poor-prognosis acute myeloid leukemia.
Leukemia and Lymphoma.
2002
Academic Article
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Times cited: 21 -
Phase I trial and correlative laboratory studies of bryostatin 1 (NSC 339555) and high-dose 1-B-D-arabinofuranosylcytosine in patients with refractory acute leukemia.
Clinical Cancer Research.
2002
Academic Article
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Times cited: 25 -
Pentostatin based non-myeloablative conditioning regimen in patients with high-risk hematologic malignancy.
Blood.
2000
Academic Article
Times cited: 1 -
Arsenic trioxide induces dose- and time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis.
Blood.
2000
Academic Article
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Times cited: 242 -
Interleukin-5 and the regulation of eosinophil production.
Current opinion in hematology.
1999
Academic Article
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Times cited: 46 - HIV/AIDS case histories: Diagnostic problems. AIDS Patient Care and STDs. 1999 Academic Article GET IT
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Hepatitis C and B-cell lymphoma.
AIDS Patient Care and STDs.
1998
Review
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Times cited: 6 -
Epidermal growth factor and basic fibroblast growth factor have independent actions on mesencephalic dopamine neurons in culture.
Journal of Neurochemistry.
1994
Academic Article
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Times cited: 39