selected publications
- Personalized medicine in the dish to prevent calcium leak associated with short-coupled polymorphic ventricular tachycardia in patient-derived cardiomyocytes. Stem cell research & therapy. 2023 Academic Article GET IT
- hiPSCs as a Unique Platform to Model Cardiogenesis in NOTCH1-Associated HLHS: hiPSCs to Model Complex Congenital Heart Defects. Circulation research. 2023 Editorial Article GET IT
- Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children. Science (New York, N.Y.). 2022 Academic Article GET IT
- Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2. Stem cell reports. 2021 Academic Article GET IT
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An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts.
Circulation research.
2021
Academic Article
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Times cited: 35 -
Modeling polymorphic ventricular tachycardia at rest using patient-specific induced pluripotent stem cell-derived cardiomyocytes.
EBioMedicine.
2020
Academic Article
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Times cited: 16 -
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.
Cell stem cell.
2020
Academic Article
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Times cited: 467 -
Inducible Pluripotent Stem Cell-Derived Cardiomyocytes Reveal Aberrant Extracellular Regulated Kinase 5 and Mitogen-Activated Protein Kinase Kinase 1/2 Signaling Concomitantly Promote Hypertrophic Cardiomyopathy in RAF1-Associated Noonan Syndrome.
Circulation.
2020
Academic Article
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Times cited: 40 -
Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene.
Stem cell research.
2018
Academic Article
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Times cited: 9 -
RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis.
Science signaling.
2014
Academic Article
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Times cited: 65 -
The role of the protein tyrosine phosphatase SHP2 in cardiac development and disease.
Seminars in cell & developmental biology.
2014
Information Resource
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Times cited: 34 -
β-adrenergic receptor stimulation transactivates protease-activated receptor 1 via matrix metalloproteinase 13 in cardiac cells.
Circulation.
2012
Academic Article
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Times cited: 77 -
Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease.
Nature medicine.
2011
Academic Article
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Times cited: 171 -
Cyclophilin A promotes cardiac hypertrophy in apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology.
2011
Academic Article
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Times cited: 69 -
Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy.
Circulation research.
2008
Academic Article
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Times cited: 94 -
Serotonin 5-HT(2B) receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice.
Hypertension (Dallas, Tex. : 1979).
2008
Academic Article
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Times cited: 37 -
Involvement of the serotonin 5-HT2B receptor in cardiac hypertrophy linked to sympathetic stimulation: control of interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha cytokine production by ventricular fibroblasts.
Circulation.
2004
Academic Article
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Times cited: 100 -
Overexpression of the serotonin 5-HT2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophy.
Circulation.
2003
Academic Article
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Times cited: 106