Balkrishna Kalayam   Associate Professor of Clinical Psychiatry

  • (914) 997-5809 (Clinical)

Brain Electrophysiology in Geriatric Depression

Depression is a major psychiatric disorder in the elderly that has comorbidity with dementia and sensory deficits (hearing and visual deficits). Electrophysiologic measures including evoked potentials are being used in this investigation to identify subgroups of depressed and depressed-demented patients with electrophysiologic abnormalities and sensory deficits, and examine its relationship to:

  1. Recovery from depression.
  2. The propensity for recurrences and the development of cognitive dysfunction/dementia.
  3. Medical morbidity, including its association with treatment resistance and relapse.

On-going projects in our laboratory include:

  1. The identification of lesion-sites in end organs as well as the auditory and visual pathways in brains of depressed and depressed-demented patients.
  2. Examining effects of correction of sensory deficits on mood, memory, and quality of life.
  3. Examining effects of memory enhancing drugs on electrophysiologic measures.


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  • ERPs, Cognitive Dysfunction, and Treatment Response of Geriatric Depression  awarded by National Institute of Mental Health Key Personnel 2007 - 2012
  • Research Fellowship in Geriatric Mood Disorders Key Personnel 2006 - 2011


Primary Affiliation

  • Weill Cornell Medical College, Cornell University


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  • Dr. Balkrishna Kalayam

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