selected publications
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Integrative Molecular Analysis of Patients With Advanced and Metastatic Cancer.
JCO precision oncology.
2019
Academic Article
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Times cited: 31 -
Upper tract urothelial carcinoma has a luminal-papillary T-cell depleted contexture and activated FGFR3 signaling.
Nature communications.
2019
Academic Article
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Times cited: 127 -
Predicting peptide presentation by major histocompatibility complex class I: an improved machine learning approach to the immunopeptidome.
BMC bioinformatics.
2019
Academic Article
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Times cited: 34 -
Immune reprogramming via PD-1 inhibition enhances early-stage lung cancer survival.
JCI insight.
2018
Academic Article
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Times cited: 43 -
Evaluation of Compound Optical Interference in High-Content Screening.
SLAS discovery : advancing life sciences R & D.
2017
Academic Article
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Times cited: 4 -
Development and validation of a whole-exome sequencing test for simultaneous detection of point mutations, indels and copy-number alterations for precision cancer care.
NPJ genomic medicine.
2016
Academic Article
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Times cited: 63 -
Proteasome Addiction Defined in Ewing Sarcoma Is Effectively Targeted by a Novel Class of 19S Proteasome Inhibitors.
Cancer research.
2016
Academic Article
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Times cited: 36 -
Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion.
Molecular cell.
2014
Academic Article
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Times cited: 300 -
Drug discovery and repurposing at Memorial Sloan Kettering Cancer Center: chemical biology drives translational medicine.
ACS chemical biology.
2014
Academic Article
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Times cited: 5 -
Discovery of a dicer-independent, cell-type dependent alternate targeting sequence generator: implications in gene silencing & pooled RNAi screens.
PloS one.
2014
Academic Article
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Times cited: 9 - Academic screening operations: RNAi screening. Combinatorial chemistry & high throughput screening. 2014 Editorial Article GET IT
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Chemical & RNAi screening at MSKCC: a collaborative platform to discover & repurpose drugs to fight disease.
Combinatorial chemistry & high throughput screening.
2014
Academic Article
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Times cited: 2 -
Death induced by CD95 or CD95 ligand elimination.
Cell reports.
2014
Academic Article
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Times cited: 60 -
Inhibition of dengue virus replication by a class of small-molecule compounds that antagonize dopamine receptor d4 and downstream mitogen-activated protein kinase signaling.
Journal of virology.
2014
Academic Article
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Times cited: 44 - Academic screening operations: small molecule screening. Combinatorial chemistry & high throughput screening. 2014 Editorial Article GET IT
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Comparative analysis of RNAi screening technologies at genome-scale reveals an inherent processing inefficiency of the plasmid-based shRNA hairpin.
Combinatorial chemistry & high throughput screening.
2014
Academic Article
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Times cited: 7 -
A 1536-well fluorescence polarization assay to screen for modulators of the MUSASHI family of RNA-binding proteins.
Combinatorial chemistry & high throughput screening.
2014
Academic Article
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Times cited: 33 -
Modulators of the microRNA biogenesis pathway via arrayed lentiviral enabled RNAi screening for drug and biomarker discovery.
Combinatorial chemistry & high throughput screening.
2013
Academic Article
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Times cited: 4 -
Systematic analysis of RNAi reports identifies dismal commonality at gene-level and reveals an unprecedented enrichment in pooled shRNA screens.
Combinatorial chemistry & high throughput screening.
2013
Academic Article
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Times cited: 27 -
A high-content assay strategy for the identification and profiling of ABCG2 modulators in live cells.
Assay and drug development technologies.
2013
Academic Article
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Times cited: 11 -
Flaviviruses are sensitive to inhibition of thymidine synthesis pathways.
Journal of virology.
2013
Academic Article
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Times cited: 24 -
A novel high throughput 1536-well Notch1 γ -secretase AlphaLISA assay.
Combinatorial chemistry & high throughput screening.
2013
Academic Article
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Times cited: 9 -
An arrayed genome-scale lentiviral-enabled short hairpin RNA screen identifies lethal and rescuer gene candidates.
Assay and drug development technologies.
2012
Academic Article
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Times cited: 13 -
Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression.
Nature biotechnology.
2012
Academic Article
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Times cited: 193 -
An arrayed RNA interference genome-wide screen identifies candidate genes involved in the MicroRNA 21 biogenesis pathway.
Assay and drug development technologies.
2012
Academic Article
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Times cited: 6 -
A simple method for analyzing actives in random RNAi screens: introducing the "H Score" for hit nomination & gene prioritization.
Combinatorial chemistry & high throughput screening.
2012
Academic Article
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Times cited: 21 -
An image-based biosensor assay strategy to screen for modulators of the microRNA 21 biogenesis pathway.
Combinatorial chemistry & high throughput screening.
2012
Academic Article
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Times cited: 18 -
A high throughput scintillation proximity imaging assay for protein methyltransferases.
Combinatorial chemistry & high throughput screening.
2012
Academic Article
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Times cited: 20 -
A high-content biosensor-based screen identifies cell-permeable activators and inhibitors of EGFR function: implications in drug discovery.
Journal of biomolecular screening.
2012
Academic Article
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Times cited: 24 -
A high-throughput scintillation proximity-based assay for human DNA ligase IV.
Assay and drug development technologies.
2011
Academic Article
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Times cited: 10 -
High-content assay to identify inhibitors of dengue virus infection.
Assay and drug development technologies.
2010
Academic Article
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Times cited: 73