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Foreign antigens and neurologic disease:  role of the immune system

 

Autoimmune disorders result from the body’s misdirected immune response to self antigens, which can lead to tissue and organ damage.  Although the specific trigger for autoimmunity is not clear in many diseases, foreign antigens have long been suspected of having a role.  Our research is focused on understanding the link between foreign antigens, particularly bacterial and dietary proteins, and the development of an immune-mediated disease process directed at the nervous system.